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MCID: CHS002
MIFTS: 25

Chiasmal Syndrome

Categories: Eye diseases, Neuronal diseases
Genes Tissues Related diseases Publications
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Aliases & Classifications for Chiasmal Syndrome

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MalaCards integrated aliases for Chiasmal Syndrome:

Name: Chiasmal Syndrome 12 15
Disorder of Optic Chiasm 12
Optic Chiasm Disorder 70
Chiasma Syndrome 12

Classifications:

MalaCards categories:
Anatomical: Eye diseases Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:5655
ICD9CM 34 377.5
SNOMED-CT 67 70476006
ICD10 32 H47.4
UMLS 70 C0155307
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Summaries for Chiasmal Syndrome

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Disease Ontology : 12 An optic nerve disease that is characterized by lesions of the optic chiasm, manifesting as various impairments of the sufferer's visual field according to the location of the lesion along the optic nerve.

MalaCards based summary : Chiasmal Syndrome, also known as disorder of optic chiasm, is related to pituitary adenoma and pituitary tumors. An important gene associated with Chiasmal Syndrome is SPESP1 (Sperm Equatorial Segment Protein 1). Affiliated tissues include pituitary, eye and thyroid.

Wikipedia : 73 Chiasmal syndrome is the set of signs and symptoms that are associated with lesions of the optic chiasm,... more...

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Related Diseases for Chiasmal Syndrome

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Diseases related to Chiasmal Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)
# Related Disease Score Top Affiliating Genes
1 pituitary adenoma 30.3 SST POMC
2 pituitary tumors 30.2 SST POMC
3 pituitary gland disease 30.0 SST POMC
4 hyperprolactinemia 29.8 SST POMC
5 acromegaly 29.6 SST POMC
6 diabetes insipidus 10.3
7 adenoma 10.2
8 yemenite deaf-blind hypopigmentation syndrome 10.1
9 hypopituitarism 10.1
10 optic nerve disease 10.1
11 scotoma 10.1
12 head injury 10.1
13 bronchial adenomas/carcinoids childhood 10.1 SST POMC
14 functionless pituitary adenoma 10.1 SST POMC
15 acidophil adenoma 10.1 SST POMC
16 ectopic cushing syndrome 10.1 SST POMC
17 tsh producing pituitary tumor 10.1 SST POMC
18 pituitary infarct 10.1 SST POMC
19 colon neuroendocrine neoplasm 10.1 SST POMC
20 pituitary-dependent cushing's disease 10.1 SST POMC
21 hormone producing pituitary cancer 10.1 SST POMC
22 nelson syndrome 10.1 SST POMC
23 pituitary apoplexy 10.1 SST POMC
24 hyperpituitarism 10.1 SST POMC
25 pituitary carcinoma 10.0 SST POMC
26 thyroid gland medullary carcinoma 10.0 SST POMC
27 functioning pituitary adenoma 10.0 SST POMC
28 acth-secreting pituitary adenoma 10.0 SST POMC
29 growth hormone secreting pituitary adenoma 10.0 SST POMC
30 gastrinoma 10.0 SST POMC
31 adrenal gland disease 10.0 SST POMC
32 ileus 10.0 SST POMC
33 carney complex variant 10.0 SST POMC
34 thyroid carcinoma, familial medullary 10.0 SST POMC
35 irritable bowel syndrome 10.0 SST POMC
36 thyroid gland disease 10.0 SST POMC
37 endocrine organ benign neoplasm 10.0 SST POMC
38 pituitary hormone deficiency, combined, 2 10.0
39 meningioma, familial 10.0
40 intracranial meningioma 10.0
41 chromophobe adenoma 10.0
42 secretory meningioma 10.0
43 lymphoplasmacyte-rich meningioma 10.0
44 exophthalmos 10.0
45 pituitary adenoma, prolactin-secreting 10.0 SST POMC
46 small cell cancer of the lung 10.0 SST POMC
47 adrenal carcinoma 10.0 SST POMC
48 multiple endocrine neoplasia 10.0 SST POMC
49 hyperthyroidism 9.9 SST POMC
50 multiple endocrine neoplasia, type i 9.9 SST POMC

Graphical network of the top 20 diseases related to Chiasmal Syndrome:



Diseases related to Chiasmal Syndrome
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Symptoms & Phenotypes for Chiasmal Syndrome

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Drugs & Therapeutics for Chiasmal Syndrome

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Search Clinical Trials , NIH Clinical Center for Chiasmal Syndrome

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Genetic Tests for Chiasmal Syndrome

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Anatomical Context for Chiasmal Syndrome

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MalaCards organs/tissues related to Chiasmal Syndrome:

40
Pituitary, Eye, Thyroid, Colon, Lung, Adrenal Gland
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Publications for Chiasmal Syndrome

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Articles related to Chiasmal Syndrome:

(show top 50) (show all 117)
# Title Authors PMID Year
1
Ischemic chiasmal syndrome associated with posterior communicating artery (PCoA) and tuberothalamic artery (TA) infarction: a case report. 61
33205375 2021
2
[Chiasmatic syndrome]. 61
33183775 2021
3
Neuro-Ophthalmic Manifestations of Intracranial Malignancies. 61
32282510 2020
4
Wilbrand's Knee: To Be or Not to Be a Knee? 61
32796340 2020
5
Sudden bilateral vision loss due to third ventricular cavernous angioma with intratumoral hemorrhage - case report. 61
31842792 2019
6
Pituitary abscess: two case reports. 61
31759391 2019
7
Infundibuloneurohypophysitis associated with autoimmune thrombocytopenia and chiasmal syndrome: a case report. 61
30128677 2019
8
Pituitary Tuberculoma. 61
29866234 2018
9
A multidisciplinary approach for the treatment of young patients with suprasellar osteochondroma. 61
29067502 2018
10
Traumatic chiasmal syndrome: A meta-analysis. 61
29577103 2018
11
Chiasmal syndrome: Clinical characteristics in patients attending an ophthalmological center. 61
29234224 2017
12
Isolated bitemporal hemianopsia due to traumatic chiasmal syndrome. 61
27135085 2016
13
Traumatic Chiasmal Syndrome: A Midline Axonal Injury. 61
27928365 2015
14
Cavernous malformation of the optic chiasm: An uncommon location. 61
25949848 2015
15
Early morphological recovery of the optic chiasm is associated with excellent visual outcome in patients with compressive chiasmal syndrome caused by pituitary tumors. 61
24938320 2015
16
Isolated complete bitemporal hemianopia in traumatic chiasmal syndrome. 61
25116786 2014
17
Neuro-ophthalmologic features of chordoid glioma. 61
24113763 2014
18
Isolated complete bitemporal hemianopia in traumatic chiasmal syndrome. 61
24212216 2013
19
Localized bi-nasal macular edema in optic chiasmal syndrome. 61
23548317 2013
20
Traumatic chiasmal syndrome. 61
22524411 2012
21
Optical coherence tomography documenting retinal nerve fiber loss in traumatic optic chiasmal syndrome. 61
21401907 2012
22
Acute, monocular vision loss from Rathke's cleft cyst. 61
22336223 2012
23
Syphilitic chorioretinitis mimicking an anterior chiasmal syndrome. 61
25389748 2012
24
Relationship between visual field sensitivity loss and quadrantic macular thickness measured with Stratus-Optical coherence tomography in patients with chiasmal syndrome. 61
21225123 2010
25
[Case of traumatic chiasmal syndrome]. 61
20593659 2010
26
Recurrent, transformed non-Hodgkin's lymphoma presenting as chiasmal syndrome with hyperprolactinemia and hypopituitarism. 61
20827870 2010
27
[Pituitary apoplexy and severe bilateral visual loss: a case report]. 61
19616868 2009
28
Suprasellar pneumatocele causing a distal optic nerve and optic chiasmal syndrome. 61
17718683 2007
29
[Visual functional changes in patients with pituitary adenoma: results of transnasal-transsphenoidal tumor removal]. 61
16826780 2006
30
A traumatic bitemporal hemianopia with macular sparing. 61
16681064 2005
31
[Optochiasmal cavernoma: a rare cause of unilateral visual loss]. 61
16106818 2005
32
Clinical features associated with lesions other than pituitary adenoma in patients with an optic chiasmal syndrome: a new perspective. 61
15734029 2005
33
Non-functioning pituitary adenomas. 61
16625856 2005
34
Clinical features associated with lesions other than pituitary adenoma in patients with an optic chiasmal syndrome. 61
15126157 2004
35
A rare primary sellar melanoma. Case report. 61
15137611 2004
36
Chiasmal syndromes. 61
14615635 2003
37
Traumatic chiasmal syndrome: a series of 19 patients. 61
12121368 2002
38
[A case of traumatic chiasmal syndrome presenting with bitemporal upper quadrantanopsia]. 61
11993180 2002
39
[Delayed radiation-induced optic neuropathy in patients with tumors in the chiasmal-sellar area after radiation therapy]. 61
11845703 2001
40
Absent relative afferent pupillary defect in an asymptomatic case of lateral chiasmal syndrome from cerebral aneurysm. 61
11349927 2001
41
Orbital drainage from cerebral arteriovenous malformations. 61
10764254 2000
42
[Endoscopic fenestration of median supratentorial cerebrospinal fluid cysts]. 61
10696675 1999
43
Regression of a large solid papillary craniopharyngioma following fractionated external radiotherapy. 61
10359146 1999
44
[Basic and clinical aspects of modern perimetry]. 61
10025112 1998
45
Traumatic chiasmal syndrome presenting with bitemporal hemianopsia. 61
9464782 1998
46
[Bitemporal hemianopsia after skull base fracture]. 61
9387167 1997
47
Wilbrand's knee of the primate optic chiasm is an artefact of monocular enucleation. 61
9440188 1997
48
Traumatic chiasmal syndrome: a feature photograph. 61
8893943 1996
49
Pituitary enlargement on magnetic resonance imaging in congenital hypothyroidism. 61
8646313 1996
50
Chiasmal syndrome. 61
7490416 1995
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Variations for Chiasmal Syndrome

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Expression for Chiasmal Syndrome

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Search GEO for disease gene expression data for Chiasmal Syndrome.
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Pathways for Chiasmal Syndrome

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GO Terms for Chiasmal Syndrome

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Molecular functions related to Chiasmal Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 SST POMC
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Sources for Chiasmal Syndrome

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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