MCID: CHL037
MIFTS: 16

Childhood Cerebellar Astrocytic Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Childhood Cerebellar Astrocytic Neoplasm

MalaCards integrated aliases for Childhood Cerebellar Astrocytic Neoplasm:

Name: Childhood Cerebellar Astrocytic Neoplasm 12
Pediatric Astrocytoma of Cerebellum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6286
NCIt 51 C6286
UMLS 74 C0278594

Summaries for Childhood Cerebellar Astrocytic Neoplasm

MalaCards based summary : Childhood Cerebellar Astrocytic Neoplasm, is also known as pediatric astrocytoma of cerebellum. The drugs Mechlorethamine and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include brain, cerebellum and bone.

Related Diseases for Childhood Cerebellar Astrocytic Neoplasm

Symptoms & Phenotypes for Childhood Cerebellar Astrocytic Neoplasm

Drugs & Therapeutics for Childhood Cerebellar Astrocytic Neoplasm

Drugs for Childhood Cerebellar Astrocytic Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 204)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1 51-75-2 4033
2
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
3
Lomustine Approved, Investigational Phase 3,Phase 1 13010-47-4 3950
4
leucovorin Approved Phase 3,Phase 2 58-05-9 143 6006
5
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
6
Vincristine Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 2068-78-2, 57-22-7 5978
7
Levoleucovorin Approved, Investigational Phase 3,Phase 2 68538-85-2
8
Etoposide Approved Phase 3,Phase 1,Phase 2,Not Applicable 33419-42-0 36462
9
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
10
Methotrexate Approved Phase 3,Phase 2 1959-05-2, 59-05-2 126941
11
Carboplatin Approved Phase 3,Phase 2,Phase 1,Not Applicable 41575-94-4 10339178 38904 498142
12
Lenograstim Approved, Investigational Phase 3,Phase 1,Phase 2 135968-09-1
13
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
14
Temozolomide Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 85622-93-1 5394
15
Thiotepa Approved, Investigational Phase 3,Phase 2,Phase 1 52-24-4 5453
16
Isotretinoin Approved Phase 3 4759-48-2 5282379 5538
17
Sargramostim Approved, Investigational Phase 3,Phase 2,Phase 1 123774-72-1, 83869-56-1
18
Procarbazine Approved, Investigational Phase 3,Phase 2,Phase 1 671-16-9 4915
19
Thioguanine Approved Phase 3 154-42-7 2723601
20
Ondansetron Approved Phase 3 99614-02-5 4595
21
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
22
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
23
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 1177-87-3
24
Histamine Approved, Investigational Phase 3,Phase 2 51-45-6 774
25
Cyproheptadine Approved Phase 3,Phase 2 129-03-3 2913
26
Calcium Approved, Nutraceutical Phase 3,Phase 2 7440-70-2 271
27
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
28
Tretinoin Approved, Investigational, Nutraceutical Phase 3 302-79-4 444795 5538
29 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
30 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
31 Hormone Antagonists Phase 3,Phase 2,Phase 1
32 glucocorticoids Phase 3,Phase 2,Phase 1
33 Folate Phase 3,Phase 2,Phase 1
34 Calcium, Dietary Phase 3,Phase 2
35 Vitamin B Complex Phase 3,Phase 2,Phase 1
36 Antimitotic Agents Phase 3,Phase 2,Phase 1,Not Applicable
37 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
38 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Phase 1,Not Applicable
39 Alkylating Agents Phase 3,Phase 2,Phase 1,Not Applicable
40
Isophosphamide mustard Phase 3,Phase 1,Phase 2 0
41 Antirheumatic Agents Phase 3,Phase 2,Phase 1
42 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1,Not Applicable
43 Dermatologic Agents Phase 3,Phase 2,Phase 1
44 Hormones Phase 3,Phase 2,Phase 1
45 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
46 Antimetabolites Phase 3,Phase 2,Phase 1
47 Immunologic Factors Phase 3,Phase 2,Phase 1,Not Applicable
48 Etoposide phosphate Phase 3,Phase 1,Phase 2,Not Applicable
49 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1,Not Applicable
50 Vitamin B9 Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 95)
# Name Status NCT ID Phase Drugs
1 Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas Unknown status NCT00278278 Phase 3 cisplatin;etoposide;ifosfamide;lomustine;methotrexate;prednisone;vincristine sulfate
2 Carboplatin Plus Vincristine in Treating Children and Adolescents With Low Grade Glioma Unknown status NCT00003015 Phase 3 carboplatin;vincristine sulfate
3 Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors Unknown status NCT00392886 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide;methotrexate;temozolomide;thiotepa;vincristine sulfate
4 High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas Completed NCT00078988 Phase 3 carboplatin;etoposide;isotretinoin;thiotepa
5 Combination Chemotherapy in Treating Children With Progressive Brain Tumors Completed NCT00002944 Phase 3 carboplatin;lomustine;procarbazine hydrochloride;thioguanine;vincristine sulfate
6 Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
7 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
8 Thiotepa and Radiation Therapy in Treating Young Patients With Newly Diagnosed Malignant Brain Tumors Unknown status NCT00313521 Phase 2 thiotepa
9 Cisplatin and Temozolomide in Treating Young Patients With Malignant Glioma Unknown status NCT00360945 Phase 2 cisplatin;temozolomide
10 Radiation Therapy in Treating Young Patients With Gliomas Unknown status NCT00238264 Phase 2
11 Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors Unknown status NCT00281905 Phase 2 carboplatin;cisplatin;cyclophosphamide;methotrexate;vincristine sulfate
12 Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor Completed NCT00004068 Phase 2 irinotecan hydrochloride;temozolomide
13 Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma Completed NCT01462695 Phase 2 Sunitinib Malate
14 Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma Completed NCT00070525 Phase 2 tipifarnib
15 Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy Completed NCT00679354 Phase 2 cilengitide
16 Carboplatin in Patients With Progressive Gliomas Completed NCT00002749 Phase 2 carboplatin
17 Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment Completed NCT00091182 Phase 2 oxaliplatin
18 Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment Completed NCT00066248 Phase 2 cyproheptadine hydrochloride;megestrol acetate
19 Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors Completed NCT00005952 Phase 1, Phase 2 temozolomide
20 Irinotecan in Treating Children With Refractory Solid Tumors Completed NCT00004078 Phase 2 irinotecan hydrochloride
21 Lobradimil and Carboplatin in Treating Children With Brain Tumors Completed NCT00019422 Phase 2 carboplatin;lobradimil
22 Vinorelbine in Treating Children With Recurrent or Refractory Cancers Completed NCT00003234 Phase 2 vinorelbine tartrate
23 Phenylacetate in Treating Children With Recurrent or Progressive Brain Tumors Completed NCT00003241 Phase 2 phenylacetate
24 Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma Completed NCT00124657 Phase 1, Phase 2 Erlotinib hydrochloride
25 Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors Completed NCT00002463 Phase 2 MOPP Regimen;Leucovorin Calcium;Mechlorethamine Hydrochloride;Methotrexate;Prednisone;Procarbazine Hydrochloride;Vincristine Sulfate
26 Docetaxel in Treating Children With Recurrent Solid Tumors Completed NCT00002825 Phase 2 docetaxel
27 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers Completed NCT00002752 Phase 1, Phase 2
28 Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma Completed NCT00008008 Phase 2 cyclophosphamide;thiotepa
29 Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma Completed NCT00006102 Phase 2 becatecarin
30 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
31 Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors Completed NCT00002608 Phase 2 cisplatin;doxorubicin hydrochloride;tamoxifen citrate
32 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
33 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
34 Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma Unknown status NCT00360854 Phase 1 erlotinib hydrochloride
35 Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors Unknown status NCT00002647 Phase 1 verteporfin
36 Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma Completed NCT00357253 Phase 1 capecitabine
37 Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors Completed NCT00019630 Phase 1 doxorubicin HCl liposome
38 Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas Completed NCT00012181 Phase 1 alvocidib
39 Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors Completed NCT00077454 Phase 1 erlotinib hydrochloride;temozolomide
40 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
41 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1 vorinostat;bortezomib
42 ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors Completed NCT00946335 Phase 1 veliparib;temozolomide
43 Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma Completed NCT00363272 Phase 1 ispinesib
44 AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors Completed NCT00326664 Phase 1 Cediranib Maleate
45 Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas Completed NCT00101270 Phase 1 irinotecan hydrochloride;oxaliplatin
46 Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors Completed NCT00100880 Phase 1 lenalidomide
47 Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors Completed NCT00005796 Phase 1 lomustine;procarbazine hydrochloride;vincristine sulfate
48 Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor Completed NCT00069940 Phase 1
49 DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas Completed NCT00004212 Phase 1 exatecan mesylate
50 Cilengitide in Treating Children With Refractory Primary Brain Tumors Completed NCT00063973 Phase 1 cilengitide

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Genetic Tests for Childhood Cerebellar Astrocytic Neoplasm

Anatomical Context for Childhood Cerebellar Astrocytic Neoplasm

MalaCards organs/tissues related to Childhood Cerebellar Astrocytic Neoplasm:

42
Brain, Cerebellum, Bone, Spinal Cord, Liver, Bone Marrow, T Cells

Publications for Childhood Cerebellar Astrocytic Neoplasm

Variations for Childhood Cerebellar Astrocytic Neoplasm

Expression for Childhood Cerebellar Astrocytic Neoplasm

Search GEO for disease gene expression data for Childhood Cerebellar Astrocytic Neoplasm.

Pathways for Childhood Cerebellar Astrocytic Neoplasm

GO Terms for Childhood Cerebellar Astrocytic Neoplasm

Sources for Childhood Cerebellar Astrocytic Neoplasm

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