MCID: CHL054
MIFTS: 12

Childhood Pleomorphic Rhabdomyosarcoma

Categories: Cancer diseases, Muscle diseases

Aliases & Classifications for Childhood Pleomorphic Rhabdomyosarcoma

MalaCards integrated aliases for Childhood Pleomorphic Rhabdomyosarcoma:

Name: Childhood Pleomorphic Rhabdomyosarcoma 12
Pleomorphic Childhood Rhabdomyosarcoma 73
Childhood Anaplastic Rhabdomyosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7463
NCIt 50 C7959
UMLS 73 C0279614

Summaries for Childhood Pleomorphic Rhabdomyosarcoma

MalaCards based summary : Childhood Pleomorphic Rhabdomyosarcoma, is also known as pleomorphic childhood rhabdomyosarcoma. The drugs Carboplatin and Dactinomycin have been mentioned in the context of this disorder. Affiliated tissues include bone.

Related Diseases for Childhood Pleomorphic Rhabdomyosarcoma

Symptoms & Phenotypes for Childhood Pleomorphic Rhabdomyosarcoma

Drugs & Therapeutics for Childhood Pleomorphic Rhabdomyosarcoma

Drugs for Childhood Pleomorphic Rhabdomyosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 54)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carboplatin Approved Phase 3,Phase 2 41575-94-4 10339178 38904 498142
2
Dactinomycin Approved, Investigational Phase 3,Phase 2 50-76-0 457193 2019
3
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
4
Cyclophosphamide Approved, Investigational Phase 3,Phase 2 6055-19-2, 50-18-0 2907
5
Vincristine Approved, Investigational Phase 3,Phase 2 57-22-7, 2068-78-2 5978
6
Ifosfamide Approved Phase 3,Phase 2 3778-73-2 3690
7
Epirubicin Approved Phase 3,Phase 2 56420-45-2 41867
8
Histamine Approved, Investigational Phase 3 51-45-6, 75614-87-8 774
9
Cyproheptadine Approved Phase 3 129-03-3 2913
10 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
11
Isophosphamide mustard Phase 3,Phase 2 0
12 Antineoplastic Agents, Phytogenic Phase 3,Phase 2
13 Immunologic Factors Phase 3,Phase 2
14 Anti-Infective Agents Phase 3,Phase 2
15 Alkylating Agents Phase 3,Phase 2
16 Antineoplastic Agents, Alkylating Phase 3,Phase 2
17 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
18 Etoposide phosphate Phase 3,Phase 2
19 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
20 Antimitotic Agents Phase 3,Phase 2
21 Antirheumatic Agents Phase 3,Phase 2
22 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
23 Immunosuppressive Agents Phase 3,Phase 2
24 Serotonin Agents Phase 3
25 Anti-Allergic Agents Phase 3
26 Serotonin Antagonists Phase 3
27 Histamine H1 Antagonists Phase 3
28
Histamine Phosphate Phase 3 51-74-1 65513
29 Antipruritics Phase 3
30 Neurotransmitter Agents Phase 3
31 Dermatologic Agents Phase 3
32 Histamine Antagonists Phase 3
33 Gastrointestinal Agents Phase 3
34
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
35
Vinblastine Approved Phase 2 865-21-4 241903 13342
36
Sirolimus Approved, Investigational Phase 2 53123-88-9 46835353 6436030 5284616
37
Bevacizumab Approved, Investigational Phase 2 216974-75-3
38
Everolimus Approved Phase 2 159351-69-6 6442177
39
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
40
Vinorelbine Approved, Investigational Phase 2 71486-22-1 60780 44424639
41
Lenograstim Approved, Investigational Phase 2 135968-09-1
42
Doxorubicin Approved, Investigational Phase 2,Phase 1 23214-92-8 31703
43
Doxil Approved June 1999 Phase 2,Phase 1 31703
44 Antibodies Phase 2,Phase 1
45 Immunoglobulin G Phase 2
46 Angiogenesis Modulating Agents Phase 2
47 Antifungal Agents Phase 2
48 Immunoglobulins Phase 2,Phase 1
49 Antibodies, Monoclonal Phase 2,Phase 1
50 Mitogens Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3 carboplatin;cyclophosphamide;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
2 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
3 Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma Completed NCT01222715 Phase 2 Cyclophosphamide;Temsirolimus;Vinorelbine Tartrate
4 Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma Completed NCT00031915 Phase 2 imatinib mesylate
5 Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors Completed NCT00025441 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
6 Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma Completed NCT00720174 Phase 1 Doxorubicin Hydrochloride
7 DNA Tests in Detecting Disseminated Disease in Tumor, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma Completed NCT01419509

Search NIH Clinical Center for Childhood Pleomorphic Rhabdomyosarcoma

Genetic Tests for Childhood Pleomorphic Rhabdomyosarcoma

Anatomical Context for Childhood Pleomorphic Rhabdomyosarcoma

MalaCards organs/tissues related to Childhood Pleomorphic Rhabdomyosarcoma:

41
Bone

Publications for Childhood Pleomorphic Rhabdomyosarcoma

Variations for Childhood Pleomorphic Rhabdomyosarcoma

Expression for Childhood Pleomorphic Rhabdomyosarcoma

Search GEO for disease gene expression data for Childhood Pleomorphic Rhabdomyosarcoma.

Pathways for Childhood Pleomorphic Rhabdomyosarcoma

GO Terms for Childhood Pleomorphic Rhabdomyosarcoma

Sources for Childhood Pleomorphic Rhabdomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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