MCID: CHL003
MIFTS: 15

Childhood Spinal Cord Tumor

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Childhood Spinal Cord Tumor

MalaCards integrated aliases for Childhood Spinal Cord Tumor:

Name: Childhood Spinal Cord Tumor 12
Childhood Spinal Cord Neoplasm 12
Childhood Spinal Cord Tumors 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3637
NCIt 50 C9234
UMLS 73 C1134515

Summaries for Childhood Spinal Cord Tumor

MalaCards based summary : Childhood Spinal Cord Tumor, is also known as childhood spinal cord neoplasm. The drugs Prednisone and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and liver.

Related Diseases for Childhood Spinal Cord Tumor

Symptoms & Phenotypes for Childhood Spinal Cord Tumor

Drugs & Therapeutics for Childhood Spinal Cord Tumor

Drugs for Childhood Spinal Cord Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 121)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
2
Vincristine Approved, Investigational Phase 3,Phase 1,Not Applicable 57-22-7, 2068-78-2 5978
3
Methotrexate Approved Phase 3 59-05-2, 1959-05-2 126941
4
leucovorin Approved Phase 3 58-05-9 6006 143
5
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
6
Cisplatin Approved Phase 3,Phase 1 15663-27-1 2767 441203 84093
7
Levoleucovorin Approved, Investigational Phase 3 68538-85-2
8
Lomustine Approved, Investigational Phase 3,Phase 2 13010-47-4 3950
9
Etoposide Approved Phase 3,Phase 1,Phase 2,Not Applicable 33419-42-0 36462
10
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
11
Dacarbazine Approved, Investigational Phase 2, Phase 3,Phase 1,Not Applicable 4342-03-4 5351166
12
Temozolomide Approved, Investigational Phase 2, Phase 3,Phase 1,Not Applicable 85622-93-1 5394
13
Bevacizumab Approved, Investigational Phase 2, Phase 3 216974-75-3
14
Vorinostat Approved, Investigational Phase 2, Phase 3,Phase 1 149647-78-9 5311
15
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
16
Isophosphamide mustard Phase 3,Phase 1,Phase 2 0
17 Hormone Antagonists Phase 3,Phase 1
18 Antirheumatic Agents Phase 3,Phase 1
19 Nucleic Acid Synthesis Inhibitors Phase 3
20 Antimetabolites Phase 3
21 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1,Not Applicable
22 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Phase 1
23 Hormones Phase 3,Phase 1
24 Immunologic Factors Phase 3,Phase 2,Phase 1,Not Applicable
25 Calcium, Dietary Phase 3
26 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 1
27 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1,Not Applicable
28 Immunosuppressive Agents Phase 3,Phase 1
29 Folic Acid Antagonists Phase 3
30 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1,Not Applicable
31 Vitamin B9 Phase 3
32 Alkylating Agents Phase 3,Phase 2,Phase 1,Not Applicable
33 Vitamin B Complex Phase 3
34 Anti-Inflammatory Agents Phase 3,Phase 1
35 Etoposide phosphate Phase 3,Phase 1,Phase 2,Not Applicable
36 Antimitotic Agents Phase 3,Phase 1,Not Applicable
37 Folate Phase 3
38 glucocorticoids Phase 3,Phase 1
39 Antimetabolites, Antineoplastic Phase 3
40 Dermatologic Agents Phase 3,Phase 2
41 Histone Deacetylase Inhibitors Phase 2, Phase 3,Phase 1
42 Antibodies Phase 2, Phase 3
43 Immunoglobulins Phase 2, Phase 3
44 Angiogenesis Modulating Agents Phase 2, Phase 3
45 Endothelial Growth Factors Phase 2, Phase 3
46 Angiogenesis Inhibitors Phase 2, Phase 3
47 Immunoglobulin G Phase 2, Phase 3
48 Antibodies, Monoclonal Phase 2, Phase 3
49 Mitogens Phase 2, Phase 3
50
Irinotecan Approved, Investigational Phase 2 100286-90-6, 97682-44-5 60838

Interventional clinical trials:

(show all 24)
# Name Status NCT ID Phase Drugs
1 Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas Unknown status NCT00278278 Phase 3 cisplatin;etoposide;ifosfamide;lomustine;methotrexate;prednisone;vincristine sulfate
2 Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma Completed NCT01236560 Phase 2, Phase 3 Temozolomide;Vorinostat
3 Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas Unknown status NCT00100802 Phase 2 lomustine;temozolomide
4 Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma Completed NCT00028795 Phase 2 temozolomide
5 Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma Completed NCT00381797 Phase 2 Irinotecan Hydrochloride
6 Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment Completed NCT00066248 Phase 2 cyproheptadine hydrochloride;megestrol acetate
7 Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma Completed NCT00124657 Phase 1, Phase 2 Erlotinib hydrochloride
8 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
9 Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma Completed NCT00363272 Phase 1 ispinesib
10 AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors Completed NCT00326664 Phase 1 Cediranib Maleate
11 FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia Completed NCT00053963 Phase 1 romidepsin
12 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
13 ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors Completed NCT00946335 Phase 1 veliparib;temozolomide
14 Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors Completed NCT00107458 Phase 1 valproic acid
15 Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors Completed NCT00003141 Phase 1 carboplatin;cisplatin;cyclophosphamide;etoposide;thiotepa;vincristine sulfate
16 SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors Completed NCT00015899 Phase 1 lonafarnib
17 PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors Completed NCT01158300 Phase 1 VEGF inhibitor PTC299
18 Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone
19 MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer Terminated NCT00572182 Phase 1 MK-0752
20 Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment Withdrawn NCT00458744 Phase 1 talotrexin
21 Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer Unknown status NCT00349024 Not Applicable polyvinylpyrrolidone-sodium hyaluronate gel
22 Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma Completed NCT00077207 Not Applicable carboplatin;temozolomide;vincristine sulfate
23 Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain Completed NCT00452868 Early Phase 1 Donepezil
24 Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas Completed NCT00276640 Not Applicable vincristine, carboplatin;vincristine, carboplatin, etoposide

Search NIH Clinical Center for Childhood Spinal Cord Tumor

Genetic Tests for Childhood Spinal Cord Tumor

Anatomical Context for Childhood Spinal Cord Tumor

MalaCards organs/tissues related to Childhood Spinal Cord Tumor:

41
Spinal Cord, Brain, Liver

Publications for Childhood Spinal Cord Tumor

Variations for Childhood Spinal Cord Tumor

Expression for Childhood Spinal Cord Tumor

Search GEO for disease gene expression data for Childhood Spinal Cord Tumor.

Pathways for Childhood Spinal Cord Tumor

GO Terms for Childhood Spinal Cord Tumor

Sources for Childhood Spinal Cord Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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