MCID: CHL067
MIFTS: 58

Cholecystitis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Cholecystitis

MalaCards integrated aliases for Cholecystitis:

Name: Cholecystitis 12 77 54 30 56 6 45 15 74
Acute Cholecystitis 12 56 15 74
Chronic Cholecystitis 12 56 74
Acute and Chronic Cholecystitis 12 74
Acalculous Cholecystitis 54 74
Calculus of Gallbladder with Cholecystitis 74
Acute on Chronic Cholecystitis 12
Gallstone Cholecystitis 54
Cholecystitis, Acute 17

Classifications:



External Ids:

Disease Ontology 12 DOID:1949
ICD9CM 36 575.10
MeSH 45 D002764
NCIt 51 C34465
SNOMED-CT 69 76581006

Summaries for Cholecystitis

Disease Ontology : 12 A cholangitis that is characterized_by an inflammation that is located in the gallbladder.

MalaCards based summary : Cholecystitis, also known as acute cholecystitis, is related to cholecystolithiasis and cholelithiasis. An important gene associated with Cholecystitis is ABCB4 (ATP Binding Cassette Subfamily B Member 4), and among its related pathways/superpathways are Pathways in cancer and Bladder cancer. The drugs Nefopam and Ketamine have been mentioned in the context of this disorder. Affiliated tissues include liver, breast and b cells, and related phenotypes are cellular and homeostasis/metabolism

Wikipedia : 77 Cholecystitis is inflammation of the gallbladder. Symptoms include right upper abdominal pain, nausea,... more...

Related Diseases for Cholecystitis

Diseases related to Cholecystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 470)
# Related Disease Score Top Affiliating Genes
1 cholecystolithiasis 32.7 ABCB4 CCK
2 cholelithiasis 32.1 ABCB4 ALB CCK CCKAR GPT
3 choledocholithiasis 30.6 ABCB4 ALB F2 GPT
4 hepatitis a 30.6 ALB F2 GPT
5 cholangitis 30.6 ABCB4 ALB F2 GPT HP
6 obstructive jaundice 30.4 ALB F2 GPT
7 gallbladder cancer 30.4 CDH1 CDKN2A MUC1 TP53
8 cholestasis 30.3 ABCB4 F2 GPT
9 cholangitis, primary sclerosing 30.3 ABCB4 ALB GPT
10 infantile liver failure syndrome 1 30.2 ALB F2 GPT
11 biliary tract disease 30.1 ABCB4 ALB CCK F2
12 hellp syndrome 30.0 F2 GPT HP
13 portal hypertension 30.0 ALB F2 GPT
14 adenocarcinoma 29.9 CDH1 CDKN2A MUC1 TP53
15 bilirubin metabolic disorder 29.9 ALB F2 GPT HP
16 ascending cholangitis 29.8 ALB CCK F2
17 acute liver failure 29.8 ALB F2 GPT
18 hepatitis e 29.8 ALB F2 GPT
19 gallbladder disease 29.7 ABCB4 CCK CCKAR
20 viral hepatitis 29.7 ALB F2 GPT KRT18
21 papillary adenocarcinoma 29.6 CDH1 MUC1 TP53
22 liver disease 29.4 ABCB4 ALB F2 GPT KRT18
23 liver cirrhosis 29.3 ALB F2 GPT KRT18
24 squamous cell carcinoma 29.2 CDH1 CDKN2A DAPK1 MUC1 TP53
25 clear cell renal cell carcinoma 28.9 CDH1 MUC1 RASSF1 TP53
26 small cell cancer of the lung 28.8 CDKN2A KRT18 RASSF1 TP53
27 esophageal cancer 28.8 ALB CDH1 CDKN2A MUC1 TP53
28 hepatocellular carcinoma 28.8 ALB CDH1 CDKN2A F2 RASSF1 TP53
29 pancreatic cancer 28.7 CCK CCKAR CDH1 CDKN2A MUC1 TP53
30 bladder cancer 28.5 CDH1 CDKN2A DAPK1 KRT18 RASSF1 TP53
31 cervical cancer 28.5 CDH1 CDKN2A DAPK1 RASSF1 TP53
32 cholangiocarcinoma 27.9 CDH1 CDKN2A DAPK1 KRT18 MUC1 RASSF1
33 acalculous cholecystitis 12.6
34 emphysematous cholecystitis 12.6
35 xanthogranulomatous cholecystitis 12.4
36 gallbladder disease 1 12.0
37 mirizzi syndrome 11.4
38 erythrocytosis, familial, 8 11.1
39 duodenal atresia 11.1
40 dicrocoeliasis 11.1
41 opisthorchiasis 11.1
42 pancreatitis 10.5
43 cerebral convexity meningioma 10.4 CDH1 TP53
44 hepatoportal sclerosis 10.4 F2 GPT
45 antipyrine metabolism 10.4 ALB F2
46 non-a-e hepatitis 10.4 ALB F2
47 epstein-barr virus hepatitis 10.4 ALB F2
48 hepatitis 10.4
49 fournier gangrene 10.4 ALB F2
50 abdominal tuberculosis 10.3 ALB F2

Comorbidity relations with Cholecystitis via Phenotypic Disease Network (PDN): (show all 13)


Acute Cystitis Acute Pancreatitis
Cholangitis Cholestasis
Chronic Myocardial Ischemia Deficiency Anemia
Esophagitis Familial Atrial Fibrillation
Heart Disease Hypertension, Essential
Ischemic Heart Disease Paralytic Ileus
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Cholecystitis:



Diseases related to Cholecystitis

Symptoms & Phenotypes for Cholecystitis

MGI Mouse Phenotypes related to Cholecystitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.06 ABCB4 ALB CCKAR CDH1 CDKN2A DAPK1
2 homeostasis/metabolism MP:0005376 10 ABCB4 ALB CCK CCKAR CDH1 CDKN2A
3 digestive/alimentary MP:0005381 9.97 ABCB4 ALB CCKAR CDH1 CDKN2A F2
4 endocrine/exocrine gland MP:0005379 9.92 ABCB4 ALB CCK CCKAR CDH1 CDKN2A
5 liver/biliary system MP:0005370 9.76 ABCB4 ALB CCKAR CDKN2A HP KRT18
6 neoplasm MP:0002006 9.5 ABCB4 ALB CDH1 CDKN2A HP RASSF1
7 renal/urinary system MP:0005367 9.1 ALB CCK CCKAR DAPK1 HP TP53

Drugs & Therapeutics for Cholecystitis

Drugs for Cholecystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 212)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nefopam Approved, Investigational Phase 4 13669-70-0
2
Ketamine Approved, Vet_approved Phase 4,Not Applicable 6740-88-1 3821
3
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
4
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
5
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613
6
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
7
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
8
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
9
Metronidazole Approved Phase 4 443-48-1 4173
10
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
11
Tigecycline Approved Phase 4 220620-09-7 5282044
12
Ceftriaxone Approved Phase 4,Phase 2 73384-59-5 5479530 5361919
13
Ursodeoxycholic acid Approved, Investigational Phase 4,Not Applicable 128-13-2 31401
14
tannic acid Approved Phase 4,Not Applicable 1401-55-4
15
Benzocaine Approved, Investigational Phase 4,Not Applicable 1994-09-7, 94-09-7 2337
16
Aprepitant Approved, Investigational Phase 4 170729-80-3 6918365 151165
17
Palonosetron Approved, Investigational Phase 4 135729-61-2, 135729-56-5, 119904-90-4 148211
18
Fosaprepitant Approved Phase 4 172673-20-0 219090
19
Acetaminophen Approved Phase 4 103-90-2 1983
20
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
21
Vitamin C Approved, Nutraceutical Phase 4,Not Applicable 50-81-7 54670067 5785
22 Hemostatics Phase 4
23 Coagulants Phase 4
24 Analgesics Phase 4,Phase 2,Not Applicable
25 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable
26 Anesthetics, Intravenous Phase 4,Not Applicable
27 Excitatory Amino Acids Phase 4,Not Applicable
28 Excitatory Amino Acid Antagonists Phase 4,Not Applicable
29 Anesthetics, Dissociative Phase 4,Not Applicable
30 Analgesics, Non-Narcotic Phase 4,Phase 2
31 Anesthetics, General Phase 4,Not Applicable
32 Central Nervous System Depressants Phase 4,Not Applicable
33 Neurotransmitter Agents Phase 4,Not Applicable
34 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
35 Vitamins Phase 4,Phase 2,Not Applicable
36 Trace Elements Phase 4,Phase 2,Not Applicable
37 Nutrients Phase 4,Phase 2,Not Applicable
38 Protective Agents Phase 4,Phase 2,Not Applicable
39 Antioxidants Phase 4,Not Applicable
40 Micronutrients Phase 4,Phase 2,Not Applicable
41 Hypnotics and Sedatives Phase 4,Not Applicable
42 Gastrointestinal Agents Phase 4,Phase 2,Not Applicable
43 Antiemetics Phase 4,Phase 2,Not Applicable
44 Autonomic Agents Phase 4,Phase 2,Not Applicable
45 Neuromuscular Agents Phase 4,Not Applicable
46 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
47 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
48 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
49 Analgesics, Opioid Phase 4,Not Applicable
50 Adrenergic Agonists Phase 4

Interventional clinical trials:

(show top 50) (show all 148)
# Name Status NCT ID Phase Drugs
1 Efficacy and Safety of Floseal for the Haemostasis During Laparoscopic Cholecystectomy in Acute Cholecystitis (GLA) Unknown status NCT01126281 Phase 4
2 Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia Unknown status NCT02493231 Phase 4 Nefopam;Ketamine;Saline
3 Uncovered Self-expandable Metal Stent Versus Double Layer Plastic Stent for Malignant Hilar Stricture Unknown status NCT01125865 Phase 4
4 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis Completed NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
5 Vitamin C Efficacy in Reducing Post Operative Pain Completed NCT01322061 Phase 4 Ascorbic Acid
6 Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy Completed NCT01833819 Phase 4 Dexmedetomidine and lidocaine;Remifentanil
7 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study Completed NCT01744847 Phase 4
8 Pain Post Abdominal Laparoscopy Prevention With Arcoxia Completed NCT00565682 Phase 4 etoricoxib 120 mg
9 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
10 Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction Completed NCT00280709 Phase 4
11 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4 ursodeoxycholic acid
12 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
13 Covered vs. Uncovered SEMS for Occluded Biliary Metal Stents Completed NCT01315522 Phase 4
14 PALONOSETRON X FOSAPREPITANT IN PONV Recruiting NCT03586817 Phase 4 Palonosetron;Fosaprepitant
15 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Enrolling by invitation NCT02812186 Phase 4 Rocuronium
16 Outcome of IV Acetaminophen Use in Laparoscopic Cholecystectomies in Patients at Risk of OSA Withdrawn NCT02056678 Phase 4 acetaminophen, IV preparation
17 Drainage is Not Necessary Procedure After Laparoscopic Cholecystectomy Due to Severe Acute Cholecystitis Unknown status NCT01625247 Phase 3
18 Single Port Access (SPA) Cholecystectomy Versus Standard Laparoscopic Cholecystectomy Unknown status NCT00904865 Phase 2, Phase 3
19 Piperacllin Versus Placebo in Patients Undergoing Surgery for Acute Cholecystitis Completed NCT02619149 Phase 3 Piperacillin-tazobactam combination product;Saline solution
20 Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy Completed NCT00447304 Phase 3 moxifloxacin
21 Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis Completed NCT01015417 Phase 3 Amoxicillin clavulanic acid
22 Doripenem in the Treatment of Complicated Intra-Abdominal Infections Completed NCT00229060 Phase 3 doripenem
23 Doripenem in the Treatment of Complicated Intra-Abdominal Infections Completed NCT00210938 Phase 3 Doripenem
24 Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease Completed NCT00370344 Phase 2, Phase 3
25 Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO) Completed NCT00495651 Phase 3 Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis;Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis
26 Surgery Or Lifestyle Intervention for Type 2 Diabetes (SOLID) Completed NCT01040468 Phase 3
27 A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA Completed NCT01686776 Phase 3
28 Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones Completed NCT02592811 Phase 3
29 A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383) Completed NCT02550288 Phase 3 Ezetimibe 10 mg;Atorvastatin 10 mg;Placebo for Ezetimibe 10 mg tablet;Placebo for Atorvastatin 10 mg capsule
30 A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384) Completed NCT02460159 Phase 3 EZ 10 mg/Atorva 20 mg FDC;EZ 10 mg/Atorva 10 mg FDC
31 A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832) Completed NCT02741245 Phase 3 Ezetimibe 10 mg;Rosuvastatin 2.5 mg;Placebo for Ezetimibe;Placebo for Rosuvastatin
32 BDD With UDCA Therapy After Laparoscopic Cholecystectomy Recruiting NCT03578055 Phase 3 BDD with UDCA;Placebo
33 A Randomized Controlled Trial on EGBD vs PC for Acute Cholecystitis. Active, not recruiting NCT02212717 Phase 2, Phase 3
34 Natural Orifice Transgastric Endoscopic Surgical Removal of the Gallbladder Unknown status NCT01174069 Phase 1, Phase 2
35 Does it Make Sense to Give Postoperative Antibiotics to Patients With an Uncomplicated Acute Cholecystitis Completed NCT00323648 Phase 2 Whether or not giving postoperatively antibiotics to patients with an uncomplicated acute cholecystitis
36 Comparisons of Intravenous Ceftriaxone With Intravenous Moxifloxacin in ERCP Completed NCT02098486 Phase 2 Moxifloxacin;ceftriaxone
37 Prospective Evaluation of the Ablation Therapy With Bipolar Radio Frequency for Nonresectable Bile Duct Cancer Recruiting NCT03679338 Phase 2
38 Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis Terminated NCT00298272 Phase 2 Placebo;Methotrexate;Etanercept;Adalimumab;Methylprednisolone
39 Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy -- Use in Acute Cholecystitis Sub-Study Completed NCT02070627 Phase 1 Indocyanine Green (ICG)
40 Transvaginal Cholecystectomy Using Endoscopic Assistance Withdrawn NCT00815438 Phase 1
41 Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study Unknown status NCT02130245 Not Applicable
42 Prediction of Postoperative Pain by Injection Pain of Propofol Unknown status NCT03021447
43 Transient ECG Changes in Patients With Acute Biliary Disease Unknown status NCT01706068
44 Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy Unknown status NCT02553551 Not Applicable Vitamin C;Placebo
45 Role of the Right Portal Pedicle and Rouviere's Sulcus as an Anatomic Landmark in Laparoscopic Cholecystectomy Unknown status NCT02133027 Not Applicable
46 Exploration of Standard Surgical Indication in Gallbladder Benign Disease Unknown status NCT02951169
47 Efficacy of Proficiency-based Versus Free Laparoscopic Training in Cholecystectomy on a Virtual Reality Simulator Unknown status NCT01615549 Not Applicable
48 Comparison of Single Trocar Cholecystectomy to Standard Laparoscopic Cholecystectomy Unknown status NCT00732550 Not Applicable
49 A Comparison of Robot-assisted Single Site and Laparoscopic Single-incision Cholecystectomy for Benign Gallbladder Unknown status NCT02485392 Not Applicable
50 Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration Unknown status NCT02461147

Search NIH Clinical Center for Cholecystitis

Cochrane evidence based reviews: cholecystitis

Genetic Tests for Cholecystitis

Genetic tests related to Cholecystitis:

# Genetic test Affiliating Genes
1 Cholecystitis 30 ABCB4

Anatomical Context for Cholecystitis

MalaCards organs/tissues related to Cholecystitis:

42
Liver, Breast, B Cells, Pancreas, Bone, Lung, Testes

The Foundational Model of Anatomy Ontology organs/tissues related to Cholecystitis:

20
The Gallbladder

Publications for Cholecystitis

Articles related to Cholecystitis:

(show top 50) (show all 3829)
# Title Authors Year
1
Infectious mononucleosis - not always a benign condition: a case report of infectious mononucleosis-associated acute acalculous cholecystitis. ( 29490709 )
2019
2
Acute Acalculous Cholecystitis in Hospitalized Patients With Hematologic Malignancies and Prognostic Importance of Gallbladder Ultrasound Findings. ( 29708270 )
2019
3
Chronic Acalculous Cholecystitis in Children With Biliary Symptoms: Usefulness of Hepatocholescintigraphy. ( 30256266 )
2019
4
Rare case report of acalculous cholecystitis: Gallbladder torsion resulting in rupture. ( 30719303 )
2019
5
Limy bile syndrome presenting as acute acalculous cholecystitis. ( 30948398 )
2019
6
Efficacy and safety of early cholecystectomy for comorbid acute cholecystitis and acute cholangitis: Retrospective cohort study. ( 30581570 )
2019
7
American Association for the Surgery of Trauma emergency general surgery guideline summaries 2018: acute appendicitis, acute cholecystitis, acute diverticulitis, acute pancreatitis, and small bowel obstruction. ( 31058240 )
2019
8
An Unusual Case of Acute Cholecystitis with Amyloidosis: A Case Report and Literature Review. ( 30449804 )
2019
9
Risk for appendicitis, cholecystitis, or diverticulitis in patients with psoriasis. ( 31039227 )
2019
10
Incomplete duodenal obstruction caused by cholecystitis in an extensive burn patient. ( 30882470 )
2019
11
Clinical and Survival Outcomes Using Percutaneous Cholecystostomy Tube Alone or Subsequent Interval Cholecystectomy to Treat Acute Cholecystitis. ( 30887298 )
2019
12
Management of Acute Cholecystitis During Pregnancy: A Single Center Experience. ( 30892681 )
2019
13
Delayed laparoscopic cholecystectomy in a case of acute cholecystitis and intestinal malrotation type I. ( 30906513 )
2019
14
Sonography of Acute Cholecystitis and Its Mimics. ( 30928076 )
2019
15
Which Is the Best Option to Relieve Symptoms of Cholecystitis in High-Risk Cirrhotic Patients? ( 30928450 )
2019
16
Natural Course of Acute Cholecystitis in Patients Treated With Percutaneous Transhepatic Gallbladder Drainage Without Elective Cholecystectomy. ( 30945085 )
2019
17
Prophylactic drainage after laparoscopic cholecystectomy for acute cholecystitis: a systematic review and meta-analysis. ( 30945148 )
2019
18
Follicular cholecystitis: Clinicopathologic associations ( 30946935 )
2019
19
Optimum timing of emergency cholecystectomy for acute cholecystitis in England: population-based cohort study. ( 30949811 )
2019
20
Laparoscopic cholecystectomy for acute cholecystitis in a patient with left-sided gallbladder: a case report. ( 30953262 )
2019
21
Meta-analysis of the cost-effectiveness of early versus delayed cholecystectomy for acute cholecystitis. ( 30957060 )
2019
22
Acalculous acute cholecystitis during the course of an enteroviral infection. ( 30975776 )
2019
23
A successful combined laparoscopic cholecystectomy and laparoscopic exploration of common bile duct for acute gangrenous cholecystitis and choledocholithiasis during pregnancy: A case report. ( 30991195 )
2019
24
Hemorrhagic Cholecystitis: A Case of Expedited Diagnosis by Point-of-Care Ultrasound in the Emergency Department. ( 31000429 )
2019
25
Hemorrhagic cholecystitis causing hemobilia and common bile duct obstruction. ( 31001409 )
2019
26
First in-Human Gallbladder Cryoablation in a Patient with Acute Calculous Cholecystitis Initially Treated with a Cholecystostomy Tube. ( 31003847 )
2019
27
The delta neutrophil index is an early predictive marker of severe acute cholecystitis. ( 31010742 )
2019
28
Management of acute cholecystitis in high-risk patients. ( 31012980 )
2019
29
A deceptive case of emphysematous cholecystitis complicated with retroperitoneal gangrene and emphysematous pancreatitis: clinical and computed tomography features. ( 31019593 )
2019
30
Successful endoscopic ultrasound-guided gallbladder drainage through the mesh of a duodenal stent for cholecystitis in a patient with pancreatic cancer. ( 31025762 )
2019
31
Bedside ultrasonography by surgeons: a new diagnostic adjunct for cholecystitis and gallstone disease. ( 31034148 )
2019
32
Case series of cancer patients who developed cholecystitis related to immune checkpoint inhibitor treatment. ( 31053161 )
2019
33
EUS-guided gallbladder drainage with a lumen-apposing metal stent versus endoscopic transpapillary gallbladder drainage for the treatment of acute cholecystitis (with videos). ( 31054909 )
2019
34
Point-of-care Ultrasound Diagnosis of Cholecystitis vs. Adenomyomatosis. ( 31061976 )
2019
35
The Effect of Leucocytosis, Gender Difference, and Ultrasound in the Diagnosis of Acute Cholecystitis in the Elderly Population. ( 31065386 )
2019
36
Acute necrotizing cholecystitis as a rare cause of mechanical small bowel obstruction. ( 31069908 )
2019
37
Acute cholecystitis in patients with stroke. ( 31085856 )
2019
38
Necrohaemorrhagic cholecystitis after renal replacement therapy. ( 31109704 )
2019
39
A resected case of gallbladder metastasis with symptoms of acute cholecystitis in multiple metastatic ductal carcinoma of the breast. ( 30109570 )
2019
40
Neutrophils injure gallbladder interstitial Cajal-like cells in a guinea pig model of acute cholecystitis. ( 30146704 )
2019
41
Three-way comparative study of endoscopic ultrasound-guided transmural gallbladder drainage using lumen-apposing metal stents versus endoscopic transpapillary drainage versus percutaneous cholecystostomy for gallbladder drainage in high-risk surgical patients with acute cholecystitis: clinical outcomes and success in an International, Multicenter Study. ( 30209610 )
2019
42
EUS-guided cholecystostomy versus endoscopic transpapillary cholecystostomy for acute cholecystitis in high-risk surgical patients. ( 30213575 )
2019
43
Cholecystectomy Vs. Cholecystostomy for the Management of Acute Cholecystitis in Elderly Patients. ( 30225792 )
2019
44
Percutaneous Cholecystostomy for Severe Acute Cholecystitis: A Useful Procedure in High-Risk Patients for Surgery. ( 30227774 )
2019
45
Early percutaneous cholecystostomy versus antibiotic treatment for mild and moderate acute cholecystitis: A retrospective cohort study. ( 30293928 )
2019
46
Antibiotic administration after cholecystectomy for acute mild-moderate cholecystitis: a PRISMA-compliant meta-analysis. ( 30327917 )
2019
47
Spontaneous Hepatic Hemorrhage Caused by Emphysematous Cholecystitis: A Case Report and Literature Review. ( 30351236 )
2019
48
Emphysematous cholecystitis and cholecystocolic fistula. ( 30371144 )
2019
49
Percutaneous Cholecystostomy Versus Conservative Treatment for Acute Cholecystitis: a Cohort Study. ( 30390182 )
2019
50
A comparison of cholecystitis grading scales. ( 30399131 )
2019

Variations for Cholecystitis

ClinVar genetic disease variations for Cholecystitis:

6 (show all 20)
# Gene Variation Type Significance SNP ID Assembly Location
1 ABCB4 NM_000443.3(ABCB4): c.959C> T (p.Ser320Phe) single nucleotide variant Conflicting interpretations of pathogenicity rs72552778 GRCh37 Chromosome 7, 87076396: 87076396
2 ABCB4 NM_000443.3(ABCB4): c.959C> T (p.Ser320Phe) single nucleotide variant Conflicting interpretations of pathogenicity rs72552778 GRCh38 Chromosome 7, 87447080: 87447080
3 ABCB4 NM_000443.3(ABCB4): c.523A> G (p.Thr175Ala) single nucleotide variant Conflicting interpretations of pathogenicity rs58238559 GRCh37 Chromosome 7, 87082273: 87082273
4 ABCB4 NM_000443.3(ABCB4): c.523A> G (p.Thr175Ala) single nucleotide variant Conflicting interpretations of pathogenicity rs58238559 GRCh38 Chromosome 7, 87452957: 87452957
5 ABCB4 NM_018849.2(ABCB4): c.3502C> T (p.Pro1168Ser) single nucleotide variant Uncertain significance rs121918442 GRCh37 Chromosome 7, 87035609: 87035609
6 ABCB4 NM_018849.2(ABCB4): c.3502C> T (p.Pro1168Ser) single nucleotide variant Uncertain significance rs121918442 GRCh38 Chromosome 7, 87406293: 87406293
7 ABCB4 NM_018849.2(ABCB4): c.1328_1329delAGinsCAA (p.Gln443Profs) indel Pathogenic rs387906528 GRCh37 Chromosome 7, 87072662: 87072663
8 ABCB4 NM_018849.2(ABCB4): c.1328_1329delAGinsCAA (p.Gln443Profs) indel Pathogenic rs387906528 GRCh38 Chromosome 7, 87443346: 87443347
9 ABCB4 NM_000443.3(ABCB4): c.1769G> A (p.Arg590Gln) single nucleotide variant Conflicting interpretations of pathogenicity rs45575636 GRCh37 Chromosome 7, 87060844: 87060844
10 ABCB4 NM_000443.3(ABCB4): c.1769G> A (p.Arg590Gln) single nucleotide variant Conflicting interpretations of pathogenicity rs45575636 GRCh38 Chromosome 7, 87431528: 87431528
11 ABCB4 NM_018849.2(ABCB4): c.1633C> G (p.Arg545Gly) single nucleotide variant Pathogenic rs397514620 GRCh37 Chromosome 7, 87069081: 87069081
12 ABCB4 NM_018849.2(ABCB4): c.1633C> G (p.Arg545Gly) single nucleotide variant Pathogenic rs397514620 GRCh38 Chromosome 7, 87439765: 87439765
13 ABCB4 NM_018849.2(ABCB4): c.101C> T (p.Thr34Met) single nucleotide variant Uncertain significance rs142794414 GRCh37 Chromosome 7, 87101971: 87101971
14 ABCB4 NM_018849.2(ABCB4): c.101C> T (p.Thr34Met) single nucleotide variant Uncertain significance rs142794414 GRCh38 Chromosome 7, 87472655: 87472655
15 ABCB4 NM_018849.2(ABCB4): c.217C> G (p.Leu73Val) single nucleotide variant Uncertain significance rs8187788 GRCh37 Chromosome 7, 87092143: 87092143
16 ABCB4 NM_018849.2(ABCB4): c.217C> G (p.Leu73Val) single nucleotide variant Uncertain significance rs8187788 GRCh38 Chromosome 7, 87462827: 87462827
17 ABCB4 NM_018849.2(ABCB4): c.3136C> T (p.Arg1046Ter) single nucleotide variant Pathogenic GRCh37 Chromosome 7, 87037496: 87037496
18 ABCB4 NM_018849.2(ABCB4): c.3136C> T (p.Arg1046Ter) single nucleotide variant Pathogenic GRCh38 Chromosome 7, 87408180: 87408180
19 ABCB4 NM_018849.2(ABCB4): c.2932T> C (p.Ser978Pro) single nucleotide variant Likely pathogenic GRCh37 Chromosome 7, 87038701: 87038701
20 ABCB4 NM_018849.2(ABCB4): c.2932T> C (p.Ser978Pro) single nucleotide variant Likely pathogenic GRCh38 Chromosome 7, 87409385: 87409385

Expression for Cholecystitis

Search GEO for disease gene expression data for Cholecystitis.

Pathways for Cholecystitis

Pathways related to Cholecystitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.28 CDH1 CDKN2A DAPK1 RASSF1 TP53
2 10.88 CDH1 CDKN2A DAPK1 RASSF1 TP53
3 10.66 CDKN2A TP53
4
Show member pathways
10.6 CDKN2A TP53
5 9.8 CCK MUC6

GO Terms for Cholecystitis

Cellular components related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 9.33 ALB F2 HP
2 extracellular exosome GO:0070062 9.23 ABCB4 ALB CDH1 F2 GPT HP
3 Golgi lumen GO:0005796 9.13 F2 MUC1 MUC6

Biological processes related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell cycle arrest GO:0007050 9.5 CDKN2A RASSF1 TP53
2 positive regulation of protein oligomerization GO:0032461 9.26 CCK TP53
3 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.16 MUC1 TP53
4 replicative senescence GO:0090399 8.96 CDKN2A TP53
5 Ras protein signal transduction GO:0007265 8.8 CDKN2A RASSF1 TP53

Sources for Cholecystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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