MCID: CHL067
MIFTS: 58

Cholecystitis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Cholecystitis

MalaCards integrated aliases for Cholecystitis:

Name: Cholecystitis 12 76 53 29 55 6 44 15 73
Acute Cholecystitis 12 55 15 73
Chronic Cholecystitis 12 55 73
Acute and Chronic Cholecystitis 12 73
Acalculous Cholecystitis 53 73
Calculus of Gallbladder with Cholecystitis 73
Acute on Chronic Cholecystitis 12
Gallstone Cholecystitis 53

Classifications:



External Ids:

Disease Ontology 12 DOID:1949
ICD9CM 35 575.10
MeSH 44 D002764
NCIt 50 C34465
SNOMED-CT 68 76581006

Summaries for Cholecystitis

Disease Ontology : 12 A cholangitis that is characterized_by an inflammation that is located in the gallbladder.

MalaCards based summary : Cholecystitis, also known as acute cholecystitis, is related to cholecystolithiasis and cholelithiasis. An important gene associated with Cholecystitis is ABCB4 (ATP Binding Cassette Subfamily B Member 4), and among its related pathways/superpathways are Pathways in cancer and Diseases of glycosylation. The drugs Amoxicillin and Nefopam have been mentioned in the context of this disorder. Affiliated tissues include liver, b cells and breast, and related phenotypes are cellular and cardiovascular system

Wikipedia : 76 Cholecystitis is inflammation of the gallbladder. Symptoms include right upper abdominal pain, nausea,... more...

Related Diseases for Cholecystitis

Diseases related to Cholecystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 444)
# Related Disease Score Top Affiliating Genes
1 cholecystolithiasis 32.4 ABCB4 CCK
2 cholelithiasis 32.3 ABCB4 ALB CCK GPT
3 cholangitis 30.5 ABCB4 ALB F2 GPT HP
4 choledocholithiasis 30.5 ABCB4 ALB F2 GPT
5 hepatitis a 30.3 ALB F2 GPT
6 hemorrhagic fever 30.2 ALB F2 GPT
7 obstructive jaundice 30.2 ALB F2 GPT
8 gallbladder cancer 30.2 CDH1 CDKN2A MUC1 MUC2 TP53
9 cholangitis, primary sclerosing 30.1 ABCB4 ALB GPT
10 cholestasis 30.0 ABCB4 F2 GPT
11 adenocarcinoma 30.0 CDH1 CDKN2A MUC1 TP53
12 biliary tract disease 30.0 ABCB4 ALB CCK F2
13 hellp syndrome 29.9 F2 GPT HP
14 ascending cholangitis 29.6 ALB CCK F2
15 infantile liver failure syndrome 1 29.6 ALB F2 GPT
16 analbuminemia 29.6 ALB F2 GPT
17 acute liver failure 29.6 ALB F2 GPT
18 hepatitis e 29.6 ALB F2 GPT
19 portal hypertension 29.6 ALB F2 GPT
20 duodenum adenocarcinoma 29.5 MUC2 MUC6
21 celiac disease 1 29.5 ALB CCK HP
22 gallbladder disease 29.4 ABCB4 CCK MUC2 TP53
23 bilirubin metabolic disorder 29.4 ALB F2 GPT HP
24 squamous cell carcinoma 29.4 CDH1 CDKN2A DAPK1 MUC1 TP53
25 cystadenoma 29.3 MUC1 MUC2 MUC6
26 viral hepatitis 29.3 ALB F2 GPT KRT18
27 liver cirrhosis 29.3 ALB F2 GPT KRT18
28 papillary adenocarcinoma 29.3 CDH1 MUC1 MUC2 TP53
29 liver disease 29.2 ABCB4 ALB F2 GPT KRT18
30 hepatocellular carcinoma 29.1 ALB CDH1 CDKN2A F2 RASSF1 TP53
31 small cell cancer of the lung 29.1 CDKN2A KRT18 RASSF1 TP53
32 clear cell renal cell carcinoma 29.1 CDH1 MUC1 RASSF1 TP53
33 cholangiocarcinoma 28.6 CDH1 DAPK1 KRT18 MUC1 MUC2 RASSF1
34 bladder cancer 28.2 CDH1 CDKN2A DAPK1 KRT18 MUC2 RASSF1
35 acalculous cholecystitis 12.5
36 emphysematous cholecystitis 12.5
37 xanthogranulomatous cholecystitis 12.3
38 gallbladder disease 1 11.9
39 mirizzi syndrome 11.4
40 bisphosphoglycerate mutase deficiency 11.0
41 duodenal atresia 11.0
42 dicrocoeliasis 11.0
43 opisthorchiasis 11.0
44 pancreatitis 10.4
45 anterior cranial fossa meningioma 10.3 F2 TP53
46 viral infectious disease 10.3
47 hepatitis 10.3
48 acute cholangitis 10.3
49 cerebral convexity meningioma 10.3 CDH1 TP53
50 hepatoportal sclerosis 10.2 F2 GPT

Comorbidity relations with Cholecystitis via Phenotypic Disease Network (PDN): (show all 13)


Acute Cystitis Acute Pancreatitis
Cholangitis Cholestasis
Chronic Myocardial Ischemia Deficiency Anemia
Esophagitis Familial Atrial Fibrillation
Heart Disease Hypertension, Essential
Ischemic Heart Disease Paralytic Ileus
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Cholecystitis:



Diseases related to Cholecystitis

Symptoms & Phenotypes for Cholecystitis

MGI Mouse Phenotypes related to Cholecystitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.02 ABCB4 ALB CDH1 CDKN2A DAPK1 HP
2 cardiovascular system MP:0005385 10.01 ABCB4 CDH1 CDKN2A F2 HP MUC2
3 digestive/alimentary MP:0005381 9.92 ABCB4 ALB CDH1 CDKN2A F2 MUC2
4 homeostasis/metabolism MP:0005376 9.9 ABCB4 ALB CCK CDH1 CDKN2A DAPK1
5 endocrine/exocrine gland MP:0005379 9.86 ABCB4 ALB CCK CDH1 CDKN2A MUC2
6 liver/biliary system MP:0005370 9.5 ABCB4 ALB CDKN2A HP KRT18 RASSF1
7 neoplasm MP:0002006 9.23 ABCB4 ALB CDH1 CDKN2A HP MUC2

Drugs & Therapeutics for Cholecystitis

Drugs for Cholecystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 206)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613
2 Nefopam Approved, Investigational Phase 4 13669-70-0
3
Ketamine Approved, Vet_approved Phase 4,Not Applicable 6740-88-1 3821
4
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
5
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
6
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
7
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
8
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
9
Metronidazole Approved Phase 4 443-48-1 4173
10
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
11
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
12
Tigecycline Approved Phase 4 220620-09-7 5282044
13
Ceftriaxone Approved Phase 4,Phase 2 73384-59-5 5479530 5361919
14
Ursodeoxycholic acid Approved, Investigational Phase 4,Not Applicable 128-13-2 31401
15
Benzocaine Approved, Investigational Phase 4,Not Applicable 94-09-7, 1994-09-7 2337
16 tannic acid Approved Phase 4,Not Applicable
17
Acetaminophen Approved Phase 4 103-90-2 1983
18
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
19
Aprepitant Approved, Investigational Phase 4 170729-80-3 6918365 151165
20
Palonosetron Approved, Investigational Phase 4 119904-90-4, 135729-61-2, 135729-56-5 148211
21
Fosaprepitant Approved Phase 4 172673-20-0 219090
22
Vitamin C Approved, Nutraceutical Phase 4,Not Applicable 50-81-7 5785 54670067
23
Substance P Investigational Phase 4 33507-63-0 44359816
24 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
25 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
26 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
27 Coagulants Phase 4
28 Hemostatics Phase 4
29 Anesthetics, Dissociative Phase 4,Not Applicable
30 Neurotransmitter Agents Phase 4,Phase 2,Not Applicable
31 Central Nervous System Depressants Phase 4,Not Applicable
32 Analgesics, Non-Narcotic Phase 4,Phase 2
33 Excitatory Amino Acids Phase 4,Not Applicable
34 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
35 Excitatory Amino Acid Antagonists Phase 4,Not Applicable
36 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable
37 Anesthetics, Intravenous Phase 4,Not Applicable
38 Analgesics Phase 4,Phase 2,Not Applicable
39 Anesthetics, General Phase 4,Not Applicable
40 Micronutrients Phase 4,Phase 2,Not Applicable
41 Trace Elements Phase 4,Phase 2,Not Applicable
42 Vitamins Phase 4,Phase 2,Not Applicable
43 Protective Agents Phase 4,Phase 2,Not Applicable
44 Antioxidants Phase 4,Not Applicable
45 Anti-Arrhythmia Agents Phase 4,Not Applicable
46 Anesthetics, Local Phase 4,Not Applicable
47 Diuretics, Potassium Sparing Phase 4,Not Applicable
48 Sodium Channel Blockers Phase 4,Not Applicable
49 Anti-Inflammatory Agents Phase 4,Phase 2,Not Applicable
50 Gastrointestinal Agents Phase 4,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 143)
# Name Status NCT ID Phase Drugs
1 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis Unknown status NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
2 Efficacy and Safety of Floseal for the Haemostasis During Laparoscopic Cholecystectomy in Acute Cholecystitis (GLA) Unknown status NCT01126281 Phase 4
3 Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia Unknown status NCT02493231 Phase 4 Nefopam;Ketamine;Saline
4 Uncovered Self-expandable Metal Stent Versus Double Layer Plastic Stent for Malignant Hilar Stricture Unknown status NCT01125865 Phase 4
5 Vitamin C Efficacy in Reducing Post Operative Pain Completed NCT01322061 Phase 4 Ascorbic Acid
6 Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy Completed NCT01833819 Phase 4 Dexmedetomidine and lidocaine;Remifentanil
7 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study Completed NCT01744847 Phase 4
8 Pain Post Abdominal Laparoscopy Prevention With Arcoxia Completed NCT00565682 Phase 4 etoricoxib 120 mg
9 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
10 Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction Completed NCT00280709 Phase 4
11 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4 ursodeoxycholic acid
12 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
13 Covered vs. Uncovered SEMS for Occluded Biliary Metal Stents Completed NCT01315522 Phase 4
14 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Enrolling by invitation NCT02812186 Phase 4 Rocuronium
15 PALONOSETRON X FOSAPREPITANT IN PONV Not yet recruiting NCT03586817 Phase 4 Palonosetron;Fosaprepitant
16 Outcome of IV Acetaminophen Use in Laparoscopic Cholecystectomies in Patients at Risk of OSA Withdrawn NCT02056678 Phase 4 acetaminophen, IV preparation
17 Drainage is Not Necessary Procedure After Laparoscopic Cholecystectomy Due to Severe Acute Cholecystitis Unknown status NCT01625247 Phase 3
18 Single Port Access (SPA) Cholecystectomy Versus Standard Laparoscopic Cholecystectomy Unknown status NCT00904865 Phase 2, Phase 3
19 Piperacllin Versus Placebo in Patients Undergoing Surgery for Acute Cholecystitis Completed NCT02619149 Phase 3 Piperacillin-tazobactam combination product;Saline solution
20 Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy Completed NCT00447304 Phase 3 moxifloxacin
21 Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis Completed NCT01015417 Phase 3 Amoxicillin clavulanic acid
22 Doripenem in the Treatment of Complicated Intra-Abdominal Infections Completed NCT00229060 Phase 3 doripenem
23 Doripenem in the Treatment of Complicated Intra-Abdominal Infections Completed NCT00210938 Phase 3 Doripenem
24 Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease Completed NCT00370344 Phase 2, Phase 3
25 Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO) Completed NCT00495651 Phase 3 Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis;Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis
26 Surgery Or Lifestyle Intervention for Type 2 Diabetes (SOLID) Completed NCT01040468 Phase 3
27 A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA Completed NCT01686776 Phase 3
28 Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones Completed NCT02592811 Phase 3
29 A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383) Completed NCT02550288 Phase 3 Ezetimibe 10 mg;Atorvastatin 10 mg;Placebo for Ezetimibe 10 mg tablet;Placebo for Atorvastatin 10 mg capsule
30 A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384) Completed NCT02460159 Phase 3 EZ 10 mg/Atorva 20 mg FDC;EZ 10 mg/Atorva 10 mg FDC
31 A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832) Completed NCT02741245 Phase 3 Ezetimibe 10 mg;Rosuvastatin 2.5 mg;Placebo for Ezetimibe;Placebo for Rosuvastatin
32 BDD With UDCA Therapy After Laparoscopic Cholecystectomy Recruiting NCT03578055 Phase 3 BDD with UDCA;Placebo
33 A Randomized Controlled Trial on EGBD vs PC for Acute Cholecystitis. Active, not recruiting NCT02212717 Phase 2, Phase 3
34 Natural Orifice Transgastric Endoscopic Surgical Removal of the Gallbladder Unknown status NCT01174069 Phase 1, Phase 2
35 Does it Make Sense to Give Postoperative Antibiotics to Patients With an Uncomplicated Acute Cholecystitis Completed NCT00323648 Phase 2 Whether or not giving postoperatively antibiotics to patients with an uncomplicated acute cholecystitis
36 Comparisons of Intravenous Ceftriaxone With Intravenous Moxifloxacin in ERCP Completed NCT02098486 Phase 2 Moxifloxacin;ceftriaxone
37 Prospective Evaluation of the Ablation Therapy With Bipolar Radio Frequency for Nonresectable Bile Duct Cancer Recruiting NCT03679338 Phase 2
38 Yttrium-90 Radioembolization With Glass Microspheres (TheraSphere) for Patients With Hepatocellular Carcinoma Terminated NCT01290523 Phase 2
39 Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis Terminated NCT00298272 Phase 2 Placebo;Methotrexate;Etanercept;Adalimumab;Methylprednisolone
40 Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy -- Use in Acute Cholecystitis Sub-Study Completed NCT02070627 Phase 1 Indocyanine Green (ICG)
41 Transvaginal Cholecystectomy Using Endoscopic Assistance Withdrawn NCT00815438 Phase 1
42 Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study Unknown status NCT02130245 Not Applicable
43 Prediction of Postoperative Pain by Injection Pain of Propofol Unknown status NCT03021447
44 Transient ECG Changes in Patients With Acute Biliary Disease Unknown status NCT01706068
45 Comparison of Effect on Quality of Recovery Outcome Between Systemic Lidocaine and Dexamethasone in Patients Undergoing Laparoscopic Cholecystectomy Unknown status NCT02224170 Not Applicable Lidocaine;Dexamethasone
46 Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy Unknown status NCT02553551 Not Applicable Vitamin C;Placebo
47 Role of the Right Portal Pedicle and Rouviere's Sulcus as an Anatomic Landmark in Laparoscopic Cholecystectomy Unknown status NCT02133027 Not Applicable
48 Exploration of Standard Surgical Indication in Gallbladder Benign Disease Unknown status NCT02951169
49 Efficacy of Proficiency-based Versus Free Laparoscopic Training in Cholecystectomy on a Virtual Reality Simulator Unknown status NCT01615549 Not Applicable
50 Comparison of Single Trocar Cholecystectomy to Standard Laparoscopic Cholecystectomy Unknown status NCT00732550 Not Applicable

Search NIH Clinical Center for Cholecystitis

Cochrane evidence based reviews: cholecystitis

Genetic Tests for Cholecystitis

Genetic tests related to Cholecystitis:

# Genetic test Affiliating Genes
1 Cholecystitis 29 ABCB4

Anatomical Context for Cholecystitis

MalaCards organs/tissues related to Cholecystitis:

41
Liver, B Cells, Breast, Testes, Lung, Pancreas, Neutrophil

The Foundational Model of Anatomy Ontology organs/tissues related to Cholecystitis:

19
The Gallbladder

Publications for Cholecystitis

Articles related to Cholecystitis:

(show top 50) (show all 2506)
# Title Authors Year
1
Derivation and validation of a practical Bedside Score for the diagnosis of cholecystitis. ( 29724580 )
2019
2
Helicobacter Pylori infection of the gallbladder and the risk of chronic cholecystitis and cholelithiasis: A systematic review and meta-analysis. ( 29266548 )
2018
3
Panparietal cholesterolosis: xantho-granulomatous cholecystitis precursor? ( 29307148 )
2018
4
Evaluation of the Safety and Efficacy of Percutaneous Transhepatic Gallbladder Drainage Combined with Laparoscopic Cholecystectomy for Treating Acute Complicated Cholecystitis. ( 29428040 )
2018
5
Performance of the Choledocholithiasis Diagnostic Score in Patients with Acute Cholecystitis. ( 29457047 )
2018
6
A Rare Pathology of Difficult Laparoscopic Cholecystectomy: Xanthogranulomatous Cholecystitis. ( 29615182 )
2018
7
Utility of Drinking Water in Hepatobiliary Scintigraphy When Possible Acute Cholecystitis Was Considered. ( 29916920 )
2018
8
Evidence-based Reviews in Surgery: Early Cholecystectomy for Cholecystitis. ( 29916874 )
2018
9
Response to Re: Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis. ( 29878697 )
2018
10
Surgical outcomes of laparoscopic cholecystectomy for acute cholecystitis in elderly patients. ( 29931750 )
2018
11
Tokyo Guidelines 2018: management bundles for acute cholangitis and cholecystitis. ( 29090868 )
2018
12
Schistosomiasis as a cause of acute cholecystitis. ( 29968897 )
2018
13
Tokyo Guidelines 2018: antimicrobial therapy for acute cholangitis and cholecystitis. ( 29090866 )
2018
14
Percutaneous cholecystostomy for severe (Tokyo 2013 stage III) acute cholecystitis. ( 29372265 )
2018
15
Conservative management of acute calculous cholecystitis complicated by pancreatitis in an elderly woman: A case report. ( 29924043 )
2018
16
Total bilirubin trend as a predictor of common bile duct stones in acute cholecystitis and symptomatic cholelithiasis. ( 29929909 )
2018
17
Efficacy of Superb Microvascular Imaging for Diagnosing Acute Cholecystitis: Comparison with Conventional Ultrasonography. ( 29936027 )
2018
18
Acute acalculous cholecystitis of an intrahepatic gallbladder causing Mirizzi's syndrome. ( 29654105 )
2018
19
A Hybrid procedure combining endoscopic gallbladder lavage and internal drainage with elective cholecystectomy for acute cholecystitis: a prospective pilot study (The BLADE study). ( 29399891 )
2018
20
Successful treatment of<i>Providencia rettgeri</i>cholecystitis and neutrophilic cholangitis in a cat. ( 29399368 )
2018
21
Tokyo Guidelines 2018: updated Tokyo Guidelines for the management of acute cholangitis/acute cholecystitis. ( 29334699 )
2018
22
Acute Acalculous Cholecystitis in Hospitalized Patients With Hematologic Malignancies and Prognostic Importance of Gallbladder Ultrasound Findings. ( 29708270 )
2018
23
Conservative Management of Acalculous Cholecystitis in a Seven-year-old Child. ( 29564197 )
2018
24
Managing acute cholecystitis among Medicaid insured in New York State: opportunities to optimize care. ( 29435753 )
2018
25
Acute acalculous cholecystitis: A new safety risk for patients with MS treated with alemtuzumab. ( 29602912 )
2018
26
An acute acalculous cholecystitis in a returned travel couple. ( 29518083 )
2018
27
Diagnostic accuracy of MDCT in differentiating gallbladder cancer from acute and xanthogranulomatous cholecystitis. ( 29679780 )
2018
28
Surgeon-Performed Ultrasound in Diagnosing Acute Cholecystitis and Appendicitis. ( 29882098 )
2018
29
Eosinophilic cholecystitis: a retrospective study spanning a fourteen-year period. ( 29898861 )
2018
30
Diffuse Xanthogranulomatous Cholecystitis: Master of Disguise. ( 29922533 )
2018
31
Metastatic Gallbladder Melanoma Presenting as Acute Emphysematous Cholecystitis. ( 29853906 )
2018
32
Acute Acalculous Cholecystitis in the Setting of Negative Ultrasound and Computed Tomography Scan of the Abdomen. ( 29719745 )
2018
33
Xanthogranulomatous cholecystitis shows overlapping histological features with IgG4-related cholecystitis. ( 29023932 )
2018
34
Unusual Manifestation of Live <i>Staphylococcus saprophyticus, Corynebacterium urinapleomorphum</i>, and <i>Helicobacter pylori</i> in the Gallbladder with Cholecystitis. ( 29933576 )
2018
35
Acute Acalculous Cholecystitis in Burns: A Review. ( 29931066 )
2018
36
An observational study of the timing of surgery, use of laparoscopy and outcomes for acute cholecystitis in the USA and UK. ( 29313126 )
2018
37
Anatomic Feasibility of Percutaneous Cholecystoenteric Fistula Creation and Stent Insertion in Acute Cholecystitis. ( 29909734 )
2018
38
Percutaneous cholecystostomy: A simple bridge to surgery or an alternative option for the management of acute cholecystitis? ( 29429546 )
2018
39
Evaluation of management and surgical outcomes in pregnancies complicated by acute cholecystitis. ( 29369817 )
2018
40
In response to the article entitled &amp;quot;The Parkland grading scale for cholecystitis&amp;quot; by Madni etA al. In Madni TD, Leshikar DE, Minshall CT, Nakonezny PA, Cornelius CC, Imran JB, Clark AT, Williams BH, Eastman AL, Minei JP, Phelan HA. The Parkland grading scale for cholecystitis. In Am J Surg; 2017 Jun 6. doi.org/10.1016/j.amjsurg.2017.05.017. ( 29397886 )
2018
41
Infectious mononucleosis - not always a benign condition: a case report of infectious mononucleosis-associated acute acalculous cholecystitis. ( 29490709 )
2018
42
Validation of the AAST EGS acute cholecystitis grade and comparison with the Tokyo guidelines. ( 29325783 )
2018
43
Meta-analysis of outcomes of endoscopic ultrasound-guided gallbladder drainage versus percutaneous cholecystostomy for the management of acute cholecystitis. ( 29404731 )
2018
44
<i>Salmonella</i> Enteritidis cholecystitis with chronic granulomatous disease. ( 29942748 )
2018
45
Eosinophilic Granulomatosis with Polyangiitis Manifested by Cholecystitis and Mononeuritis Multiplex: A Case Report. ( 29892153 )
2018
46
Hemorrhagic Cholecystitis after Warfarin Use for Deep Vein Thrombosis. ( 29922722 )
2018
47
Riddle Me This: Acalculous Cholecystitis as an Unusual Complication of Immunoglobulin M Negative Mononucleosis. ( 29930883 )
2018
48
A Case of Melioidosis Presenting as Acalculous Cholecystitis. ( 30148016 )
2018
49
Correction to: Acute acalculous cholecystitis determining Mirizzi syndrome: case report and literature review. ( 30165833 )
2018
50
A case of multi-drug resistant ESBL-producing Shigella sonnei acute acalculous cholecystitis and gastroenteritis in a returned traveller. ( 30169854 )
2018

Variations for Cholecystitis

ClinVar genetic disease variations for Cholecystitis:

6 (show all 16)
# Gene Variation Type Significance SNP ID Assembly Location
1 ABCB4 NM_000443.3(ABCB4): c.959C> T (p.Ser320Phe) single nucleotide variant Conflicting interpretations of pathogenicity rs72552778 GRCh37 Chromosome 7, 87076396: 87076396
2 ABCB4 NM_000443.3(ABCB4): c.959C> T (p.Ser320Phe) single nucleotide variant Conflicting interpretations of pathogenicity rs72552778 GRCh38 Chromosome 7, 87447080: 87447080
3 ABCB4 NM_000443.3(ABCB4): c.523A> G (p.Thr175Ala) single nucleotide variant Conflicting interpretations of pathogenicity rs58238559 GRCh37 Chromosome 7, 87082273: 87082273
4 ABCB4 NM_000443.3(ABCB4): c.523A> G (p.Thr175Ala) single nucleotide variant Conflicting interpretations of pathogenicity rs58238559 GRCh38 Chromosome 7, 87452957: 87452957
5 ABCB4 NM_018849.2(ABCB4): c.3502C> T (p.Pro1168Ser) single nucleotide variant Uncertain significance rs121918442 GRCh37 Chromosome 7, 87035609: 87035609
6 ABCB4 NM_018849.2(ABCB4): c.3502C> T (p.Pro1168Ser) single nucleotide variant Uncertain significance rs121918442 GRCh38 Chromosome 7, 87406293: 87406293
7 ABCB4 NM_018849.2(ABCB4): c.1328_1329delAGinsCAA (p.Gln443Profs) indel Pathogenic rs387906528 GRCh37 Chromosome 7, 87072662: 87072663
8 ABCB4 NM_018849.2(ABCB4): c.1328_1329delAGinsCAA (p.Gln443Profs) indel Pathogenic rs387906528 GRCh38 Chromosome 7, 87443346: 87443347
9 ABCB4 NM_000443.3(ABCB4): c.1769G> A (p.Arg590Gln) single nucleotide variant Conflicting interpretations of pathogenicity rs45575636 GRCh37 Chromosome 7, 87060844: 87060844
10 ABCB4 NM_000443.3(ABCB4): c.1769G> A (p.Arg590Gln) single nucleotide variant Conflicting interpretations of pathogenicity rs45575636 GRCh38 Chromosome 7, 87431528: 87431528
11 ABCB4 NM_018849.2(ABCB4): c.1633C> G (p.Arg545Gly) single nucleotide variant Pathogenic rs397514620 GRCh37 Chromosome 7, 87069081: 87069081
12 ABCB4 NM_018849.2(ABCB4): c.1633C> G (p.Arg545Gly) single nucleotide variant Pathogenic rs397514620 GRCh38 Chromosome 7, 87439765: 87439765
13 ABCB4 NM_018849.2(ABCB4): c.3629C> G (p.Ser1210Ter) single nucleotide variant Pathogenic rs748842753 GRCh37 Chromosome 7, 87032476: 87032476
14 ABCB4 NM_018849.2(ABCB4): c.3629C> G (p.Ser1210Ter) single nucleotide variant Pathogenic rs748842753 GRCh38 Chromosome 7, 87403160: 87403160
15 ABCB4 NM_018849.2(ABCB4): c.1015delT (p.Ser339Glnfs) deletion Pathogenic rs753104429 GRCh38 Chromosome 7, 87444966: 87444966
16 ABCB4 NM_018849.2(ABCB4): c.1015delT (p.Ser339Glnfs) deletion Pathogenic rs753104429 GRCh37 Chromosome 7, 87074282: 87074282

Expression for Cholecystitis

Search GEO for disease gene expression data for Cholecystitis.

Pathways for Cholecystitis

GO Terms for Cholecystitis

Cellular components related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.56 ABCB4 ALB CDH1 F2 GPT HP
2 blood microparticle GO:0072562 9.33 ALB F2 HP
3 Golgi lumen GO:0005796 8.92 F2 MUC1 MUC2 MUC6

Biological processes related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell cycle arrest GO:0007050 9.61 CDKN2A RASSF1 TP53
2 positive regulation of protein oligomerization GO:0032461 9.4 CCK TP53
3 maintenance of gastrointestinal epithelium GO:0030277 9.37 MUC2 MUC6
4 Ras protein signal transduction GO:0007265 9.33 CDKN2A RASSF1 TP53
5 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.32 MUC1 TP53
6 replicative senescence GO:0090399 9.26 CDKN2A TP53
7 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.13 MUC1 MUC2 MUC6
8 O-glycan processing GO:0016266 8.8 MUC1 MUC2 MUC6

Sources for Cholecystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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