MCID: CHL067
MIFTS: 58

Cholecystitis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Cholecystitis

MalaCards integrated aliases for Cholecystitis:

Name: Cholecystitis 12 74 52 29 54 43 15 71 32
Acute Cholecystitis 12 54 15 71 32
Chronic Cholecystitis 12 54 71 32
Acute and Chronic Cholecystitis 12 71
Acalculous Cholecystitis 52 71
Calculus of Gallbladder with Cholecystitis 71
Acute on Chronic Cholecystitis 12
Gallstone Cholecystitis 52
Cholecystitis, Acute 17

Classifications:



External Ids:

Disease Ontology 12 DOID:1949
ICD9CM 34 575.10
MeSH 43 D002764
NCIt 49 C34465
SNOMED-CT 67 76581006
UMLS 71 C0008325 C0085694 C0149520 more

Summaries for Cholecystitis

Disease Ontology : 12 A cholangitis that is characterized by an inflammation that is located in the gallbladder.

MalaCards based summary : Cholecystitis, also known as acute cholecystitis, is related to emphysematous cholecystitis and acalculous cholecystitis. An important gene associated with Cholecystitis is CCK (Cholecystokinin), and among its related pathways/superpathways are Innate Immune System and Gastric cancer. The drugs Ketamine and Nefopam have been mentioned in the context of this disorder. Affiliated tissues include gallbladder, liver and heart, and related phenotypes are homeostasis/metabolism and cellular

Wikipedia : 74 Cholecystitis is inflammation of the gallbladder. Symptoms include right upper abdominal pain, nausea,... more...

Related Diseases for Cholecystitis

Diseases related to Cholecystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 864)
# Related Disease Score Top Affiliating Genes
1 emphysematous cholecystitis 34.9 GPT F2
2 acalculous cholecystitis 34.3 GPT F2 CCKAR CCK ALB
3 cholelithiasis 32.9 HP GPT CCKAR CCK ALB
4 dicrocoeliasis 32.5 GPT ALB
5 gallbladder disease 32.5 TP53 GPT EGFR CDH1 CCKAR CCK
6 choledocholithiasis 31.6 GPT F2 CCK ALB
7 pancreatitis 31.4 TP53 CDKN2A CCKAR CCK
8 acute cholangitis 31.3 MUC5AC GPT F2 ALB
9 obstructive jaundice 31.2 TLR4 GPT F2 ALB
10 cholangitis 31.2 TP53 TLR4 HP GPT F2 ALB
11 typhoid fever 31.2 TLR4 GPT F2 ALB
12 biliary tract disease 31.1 TP53 GPT F2 CCK ALB
13 acute pancreatitis 31.1 TLR4 GPT CCKAR CCK ALB
14 appendicitis 31.1 TLR4 S100A9 S100A8 ALB
15 pyelonephritis 31.0 TLR4 GPT ALB
16 gallbladder cancer 30.9 TP53 MUC1 EGFR EGF CDKN2A CDH1
17 bilirubin metabolic disorder 30.8 HP GPT F2 ALB
18 volvulus of midgut 30.8 GPT F2 ALB
19 cholestasis 30.8 GPT F2 CP CCK ALB
20 diverticulitis 30.8 S100A9 MUC5AC ALB
21 ascending cholangitis 30.7 GPT F2 ALB
22 exanthem 30.7 GPT F2 EGFR ALB
23 peptic ulcer disease 30.7 TP53 S100A8 MUC5AC CAT ALB
24 hepatitis a 30.7 TLR4 HP GPT F2 ALB
25 respiratory failure 30.7 MUC5AC GPT F2 CAT ALB
26 gastroenteritis 30.7 CP CDH1 CAT ALB
27 duodenitis 30.7 S100A8 CCK ALB
28 sclerosing cholangitis 30.6 TLR4 HP GPT F2 ALB
29 cystitis 30.6 TP53 TLR4 EGF CDH1
30 aspiration pneumonia 30.6 GPT F2 ALB
31 duodenal ulcer 30.6 TLR4 S100A8 EGF CCK CAT
32 endocarditis 30.6 F2 CAT ALB
33 pericardial effusion 30.6 GPT F2 ALB
34 paralytic ileus 30.6 GPT F2 ALB
35 liver cirrhosis 30.5 HP GPT F2 CP ALB
36 schistosomiasis 30.5 TP53 GPT F2 ALB
37 acute kidney failure 30.5 HP GPT F2 EGF CAT ALB
38 diarrhea 30.5 TLR4 GPT EGFR CCK ALB
39 hepatic infarction 30.4 GPT F2 ALB
40 dengue hemorrhagic fever 30.4 GPT F2 ALB
41 hepatic coma 30.4 GPT F2 ALB
42 fascioliasis 30.4 GPT CP ALB
43 portal hypertension 30.4 TLR4 GPT F2 ALB
44 hepatorenal syndrome 30.4 GPT F2 ALB
45 splenic infarction 30.4 HP GPT F2
46 papillary adenocarcinoma 30.3 TP53 MUC1 CDH1
47 intrahepatic cholangiocarcinoma 30.3 TP53 MUC5AC MUC1 EGFR CDH1 ALB
48 gastritis 30.3 TP53 TLR4 S100A8 MUC6 CDH1 CAT
49 end stage renal failure 30.3 MUC1 CP CAT ALB
50 cystadenocarcinoma 30.2 TP53 MUC5AC MUC1

Comorbidity relations with Cholecystitis via Phenotypic Disease Network (PDN): (show all 11)


Acute Cystitis Acute Pancreatitis
Cholangitis Cholestasis
Deficiency Anemia Esophagitis
Familial Atrial Fibrillation Heart Disease
Hypertension, Essential Paralytic Ileus
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Cholecystitis:



Diseases related to Cholecystitis

Symptoms & Phenotypes for Cholecystitis

MGI Mouse Phenotypes related to Cholecystitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.2 ALB CAT CCK CCKAR CDH1 CDKN2A
2 cellular MP:0005384 10.18 ALB CAT CCKAR CDH1 CDKN2A CP
3 digestive/alimentary MP:0005381 10.07 ALB CCKAR CDH1 CDKN2A EGF EGFR
4 immune system MP:0005387 10.03 ALB CDH1 CDKN2A CP EGF EGFR
5 liver/biliary system MP:0005370 9.76 ALB CCKAR CDKN2A CP EGFR HP
6 neoplasm MP:0002006 9.56 ALB CAT CDH1 CDKN2A EGFR HP
7 renal/urinary system MP:0005367 9.23 ALB CCK CCKAR DAPK1 EGFR HP

Drugs & Therapeutics for Cholecystitis

Drugs for Cholecystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 174)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
2
Nefopam Approved, Investigational Phase 4 13669-70-0
3
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
4
Metronidazole Approved Phase 4 443-48-1 4173
5
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
6
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
7
Tigecycline Approved Phase 4 220620-09-7 5282044
8 Hydrotalcite Approved, Experimental, Investigational Phase 4 12304-65-3
9
Aluminum hydroxide Approved, Investigational Phase 4 21645-51-2
10
Magnesium hydroxide Approved, Investigational Phase 4 1309-42-8
11
Sucralfate Approved Phase 4 54182-58-0
12
Remifentanil Approved Phase 4 132875-61-7 60815
13
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
14
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
15
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
16
tannic acid Approved Phase 4 1401-55-4
17
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
18
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
19
Fosaprepitant Approved Phase 4 172673-20-0 219090
20
Aprepitant Approved, Investigational Phase 4 170729-80-3 151165 6918365
21
Palonosetron Approved, Investigational Phase 4 135729-61-2, 135729-56-5, 119904-90-4 148211
22
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
23
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
24
Aspartic acid Approved, Nutraceutical Phase 4 56-84-8 5960
25 Hemostatics Phase 4
26 Coagulants Phase 4
27 Anesthetics, Dissociative Phase 4
28 Excitatory Amino Acid Antagonists Phase 4
29 Excitatory Amino Acids Phase 4
30 Antibiotics, Antitubercular Phase 4
31 Anti-Bacterial Agents Phase 4
32 Anti-Infective Agents Phase 4
33 Vitamins Phase 4
34 Trace Elements Phase 4
35 Micronutrients Phase 4
36 Antioxidants Phase 4
37 Nutrients Phase 4
38 Protective Agents Phase 4
39 Hypnotics and Sedatives Phase 4
40 Anesthetics, General Phase 4
41 Analgesics, Opioid Phase 4
42 Anesthetics, Intravenous Phase 4
43 Antiparasitic Agents Phase 4
44 Antiprotozoal Agents Phase 4
45 Anti-Ulcer Agents Phase 4
46 Adjuvants, Immunologic Phase 4
47 Almagate Phase 4
48 Antacids Phase 4
49 Immunologic Factors Phase 4
50 Adrenergic Agonists Phase 4

Interventional clinical trials:

(show top 50) (show all 182)
# Name Status NCT ID Phase Drugs
1 THE USE OF FLOSEAL GELATIN MATRIX FOR THE HAEMOSTASIS DURING LAPAROSCOPIC CHOLECYSTECTOMY FOR ACUTE CHOLECYSTITIS; EFFICACY AND SAFETY EVALUATED IN A MULTICENTER, PROSPECTIVE, OPEN LABEL TRIAL WITH AN HISTORICAL CONTROL GROUP. (G.L.A. STUDY: GELATIN Matrix in Laparoscopic Cholecystectomy for Acute Cholecystitis) Unknown status NCT01126281 Phase 4
2 DOLCE Study: Day-care Versus Overnight-stay Laparoscopic Cholecystectomy Randomized, Controlled Trial Unknown status NCT01052727 Phase 4
3 Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia Unknown status NCT02493231 Phase 4 Nefopam;Ketamine;Saline
4 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy Due to Acute Cholecystitis. Is it Necessary? Completed NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
5 A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
6 Studie Naar De Effectiviteit Van Ursodeoxycholzuur Ter Preventie Van Galsteen-Gerelateerde Klachten Bij patiënten in Afwachting Van Een Cholecystectomie Completed NCT00161083 Phase 4 ursodeoxycholic acid
7 The Role of a Single Oral Dose (2g) of Vitamin C in Reducing Intensity of Pain and Opioids Consumption in Patients Undergoing Laparoscopic Cholecystectomy. A Randomized, Double-blinded, Placebo-controlled Study Completed NCT01322061 Phase 4 Ascorbic Acid
8 A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment: Randomized Trial Completed NCT03635372 Phase 4 Alginate;Sucralfate;Hydrotalcite
9 Opioid-free Total Intravenous Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy; Comparison With Propofol, Remifentanil Infusions Completed NCT01833819 Phase 4 Dexmedetomidine and lidocaine;Remifentanil
10 Pain Post Abdominal Laparoscopy Prevention With Arcoxia Completed NCT00565682 Phase 4 etoricoxib 120 mg
11 Covered Versus Uncovered Metal Stents for Management of Distal Malignant Biliary Obstruction? Results of a Randomized Prospective Study. Completed NCT00280709 Phase 4
12 A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
13 Effect of Deep Versus Moderate Neuromuscular Blockade on Peak Airway Pressures During Elective Laparoscopic Surgery Completed NCT02812186 Phase 4 Rocuronium
14 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Randomized Multi-center Study Completed NCT01744847 Phase 4
15 Multi-Port vs. Single-port Cholecystectomy Completed NCT01104727 Phase 4
16 COMPARATIVE STUDY BETWEEN PALONOSETRON AND FOSAPREPITANT IN THE PROFILAXIA OF POSTOPERATIVE NAUSEA AND VOMITING IN WOMEN SUBMITTED TO VIDEOLAPAROSCOPIC COLECISTECTOMIES Recruiting NCT03586817 Phase 4 Palonosetron;Fosaprepitant
17 The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders Terminated NCT02472509 Phase 4 Ursodeoxycholic Acid
18 Use of IV Acetaminophen Intraoperatively in Obese Patients at Risk for Obstructive Sleep Apnea Undergoing Laparoscopic Cholecystectomy Withdrawn NCT02056678 Phase 4 acetaminophen, IV preparation
19 Drainage is Not Necessary Procedure After Laparoscopic Cholecystectomy Due to Severe Acute Cholecystitis Unknown status NCT01625247 Phase 3
20 Single Port Access Cholecystectomy Versus Standard Laparoscopic Cholecystectomy - Randomized Study Unknown status NCT00904865 Phase 2, Phase 3
21 Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy = ACDC-study Completed NCT00447304 Phase 3 moxifloxacin
22 Endosonography-guided Gallbladder Drainage (EGBD) Versus Percutaneous Cholecystostomy (PC) in Patients Suffering From Acute Cholecystitis That Are Unsuitable for Surgery. A Randomized Controlled Trial. Completed NCT02212717 Phase 2, Phase 3
23 Piperacllin Versus Placebo in Patients Undergoing Surgery for Acute Cholecystitis Completed NCT02619149 Phase 3 Piperacillin-tazobactam combination product;Saline solution
24 Antibiotic Treatment Versus no Antibiotics in the Postoperative Acute Cholecystitis Low and Moderately Severe Completed NCT01015417 Phase 3 Amoxicillin clavulanic acid
25 A Multicenter, Double-Blind, Randomized, Phase 3 Study of Doripenem Versus Comparator Antibiotic in the Treatment of Complicated Intra-Abdominal Infections Completed NCT00210938 Phase 3 Doripenem
26 A Multicenter, Double-Blind, Randomized, Phase 3 Study of Doripenem Versus Comparator Antibiotic in the Treatment of Complicated Intra-Abdominal Infections Completed NCT00229060 Phase 3 doripenem
27 Dexamethasone Improves Postoperative Symptoms in Patients Undergoing Elective Laparoscopic Cholecystectomy: A Randomised Clinical Trial. Completed NCT01030614 Phase 3 Dexamethasone;placebo
28 Prospective Randomized Clinical Trial Comparing Single Incision Laparoscopic Surgery vs Flexible Single Incision Surgery on Cholecystectomy Completed NCT01558414 Phase 3
29 Residual Gastric Volume Measured by Upper Digestive Endoscopy 2h After the Ingestion of a Beverage Containing Carbohydrates Plus Whey Protein. A Controlled, Randomized Clinical Trial Completed NCT01828645 Phase 2, Phase 3
30 An Expertise-based Randomized Controlled Trial Comparing Minilaparotomy Cholecystectomy and Laparoscopic Cholecystectomy Completed NCT00370344 Phase 2, Phase 3
31 Prospective Study for the Effects of Biphenyl Dimethyl Dicarboxylate and Ursodeoxycolic Acid Therapy on Liver Function and Quality of Life After Laparoscopic Cholecystectomy Recruiting NCT03578055 Phase 3 BDD with UDCA;Placebo
32 Does it Make Sense to Give Postoperative Antibiotics to Patients With an Uncomplicated Acute Cholecystitis Completed NCT00323648 Phase 2 Whether or not giving postoperatively antibiotics to patients with an uncomplicated acute cholecystitis
33 Antibiotic Prophylaxis for ERCP: a Comparison of Intravenous Ceftriaxone With Intravenous Moxifloxacin in the Prophylaxis of Cholangitis Completed NCT02098486 Phase 2 Moxifloxacin;ceftriaxone
34 Efficacy and Safety of Dengue Vaccine in Healthy Children Aged 4 to 11 Years in Thailand Completed NCT00842530 Phase 2
35 MANAGEMENT OF THE PATIENT WITH ACUTE ABDOMEN SUBMITTED TO URGENT ABDOMINAL SURGERY: a Pilot Randomized Multicentre Study Completed NCT01911702 Phase 2
36 Pilot Study to Assess Safety and Efficacy Of An Endoscopic Bipolar Radiofrequency Probe (EndoHPB) In the Management of Unresectable Bile Duct and Pancreatic Cancer Unknown status NCT02042859 Phase 1
37 Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy Sub-Study Completed NCT02070627 Phase 1 Indocyanine Green (ICG)
38 Pilot Study to Assess the Safety and Pharmacokinetics of 70-150μm Drug Eluting Beads Loaded With Irinotecan (DEBIRI) in the Treatment of Hepatic Colorectal Metastases Completed NCT02350400 Phase 1
39 Prospective Single-Arm Pilot Study for CT-Guided, Temporary Celiac Ganglion Block as a Test Before Celiac Ganglion Resection for Dysautonomia-Related Bowel Dysmotility Recruiting NCT04121338 Phase 1 Liposomal bupivacaine
40 Phase I Clinical Trial on Intra-tumoral Ipilimumab Plus Intravenous Nivolumab Following the Resection of Recurrent Glioblastoma Recruiting NCT03233152 Phase 1 Ipilimumab (YervoyTM, 50 mg/10 mL solution);Nivolumab (OpdivoTM, 40 mg/4mL solution)
41 Laparoscopic Cholecystectomy Using Transvaginal Endoscopic Assistance Withdrawn NCT00815438 Phase 1
42 Percutaneous Drainage in a Setting of Acute Cholecystitis Severity Grade III and Correlation With Clinical Outcomes Unknown status NCT03087747
43 Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study Unknown status NCT02130245
44 Transient ECG Changes in Patients With Acute Biliary Disease Unknown status NCT01706068
45 A Comparison of Robot-assisted Single Site and Laparoscopic Single-incision Cholecystectomy for Benign Gallbladder Unknown status NCT02485392
46 Prediction of Postoperative Pain by Injection Pain of Propofol Unknown status NCT03021447
47 Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy; a A Prospective Randomized Controlled Trial Unknown status NCT02553551 Vitamin C;Placebo
48 Efficacy of Hemopatch in Reducing of Postoperative Bleeding After Laparoscopic Cholecystectomy: Prosective and Multicenter Study Unknown status NCT02777307
49 Comparison of Single Trocar Cholecystectomy to Standard Laparoscopic Cholecystectomy Unknown status NCT00732550
50 A Randomized Controlled Trial Comparing a Solo and Non-solo Approach for Laparoscopic Cholecystectomy Unknown status NCT02978989

Search NIH Clinical Center for Cholecystitis

Cochrane evidence based reviews: cholecystitis

Genetic Tests for Cholecystitis

Genetic tests related to Cholecystitis:

# Genetic test Affiliating Genes
1 Cholecystitis 29

Anatomical Context for Cholecystitis

The Foundational Model of Anatomy Ontology organs/tissues related to Cholecystitis:

19
Gallbladder

MalaCards organs/tissues related to Cholecystitis:

40
Liver, Heart, Testes, Pancreas, Kidney, Colon, Lung

Publications for Cholecystitis

Articles related to Cholecystitis:

(show top 50) (show all 13850)
# Title Authors PMID Year
1
Gallbladder carcinoma manifesting as acute cholecystitis: clinical and computed tomographic features. 54 61
19744453 2009
2
Acute transient hepatocellular injury in cholelithiasis and cholecystitis without evidence of choledocholithiasis. 54 61
19673021 2009
3
Usefulness of fatty meal-stimulated cholescintigraphy in the diagnosis and treatment of chronic acalculous cholecystitis. 54 61
19225936 2009
4
Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder. 54 61
18182589 2008
5
Liver enzyme elevation and normal pulmonary function in an adult with a declining forced expiratory volume in 1 second. 54 61
18534093 2008
6
Effect of sequential administration of an opioid and cholecystokinin on gallbladder ejection fraction: brief communication. 54 61
16954554 2006
7
Stimulation with fatty meal (Lipomul) to assess gallbladder emptying in children with chronic acalculous cholecystitis. 54 61
12883305 2003
8
Bradykinin B2 receptors mediate contraction in the normal and inflamed human gallbladder in vitro. 54 61
12851878 2003
9
Influence of cholecystitis state on pharmacological response to cholecystokinin of isolated human gallbladder with gallstones. 54 61
12772786 2003
10
Gallbladder ejection fraction: an accurate evaluation of symptomatic acalculous gallbladder disease. 54 61
12872903 2003
11
Mechanisms of impaired gallbladder contractile response in chronic acalculous cholecystitis. 54 61
12022997 2002
12
Cholecystokinin cholescintigraphy: victim of its own success? 54 61
10616884 1999
13
Chronic acalculous cholecystitis: reproduction of pain with cholecystokinin and relief of symptoms with cholecystectomy. 54 61
10388344 1999
14
The clinical utility of quantitative cholescintigraphy: the significance of gallbladder dysfunction. 54 61
9596151 1998
15
Acute cholecystitis in AIDS patients: correlation of Tc-99m hepatobiliary scintigraphy with histopathologic laboratory findings and CD4 counts. 54 61
9554194 1998
16
Pharmacologic intervention for the diagnosis of acute cholecystitis: cholecystokinin pretreatment or morphine, or both? 54 61
9098218 1997
17
Cholecystokinin and morphine pharmacological intervention during 99mTc-HIDA cholescintigraphy: a rational approach. 54 61
8623048 1996
18
Abnormal gallbladder nuclear ejection fraction predicts success of cholecystectomy in patients with biliary dyskinesia. 54 61
8273847 1993
19
Cholecystokinin cholescintigraphy: detection of abnormal gallbladder motor function in patients with chronic acalculous gallbladder disease. 54 61
1880571 1991
20
[The blood level of cobalamin as an indicator of the functional status of the liver in jaundice of different etiologies]. 54 61
1721943 1991
21
Chronic right upper quadrant pain without gallstones: does HIDA scan predict outcome after cholecystectomy? 54 61
2375327 1990
22
[Sonographic criteria of acute acalculous cholecystitis.Critical observation of the clinical records of sedated, ventilated and parenterally nourished patients]. 54 61
2121670 1990
23
Cholecystokinin sonography: lack of utility in diagnosis of acute acalculous cholecystitis. 54 61
2183285 1990
24
Histopathological Examination of Gallbladder Specimens in Kumaon Region of Uttarakhand. 61
30847742 2020
25
Endoscopic ultrasound-guided gallbladder drainage, transpapillary drainage, or percutaneous drainage in high risk acute cholecystitis patients: a systematic review and comparative meta-analysis. 61
31645067 2020
26
Effect of hospital teaching status on endoscopic retrograde cholangiopancreatography mortality and complications in the USA. 61
32030551 2020
27
Efficacy of combined bland embolization and chemoembolization for huge (≥10 cm) hepatocellular carcinoma. 61
32031474 2020
28
Cholecystectomy during esophagectomy is safe but unnecessary. 61
30618322 2020
29
Carcinosarcoma (adenocarcinoma, neuroendocrine carcinoma, undifferentiated carcinoma and chondrosarcoma) of the gallbladder. 61
31264080 2020
30
Percutaneous gallbladder drainage as a bridge to concomitant coronary artery bypass grafting and laparoscopic cholecystectomy. 61
31730718 2020
31
A Simple Risk Score to Predict Clavien-Dindo Grade IV and V Complications After Non-elective Cholecystectomy. 61
32030602 2020
32
Improved outcomes for index cholecystectomy for acute cholecystitis following a dedicated emergency surgery and trauma service (ESAT). 61
32020247 2020
33
Evaluation of the CT Scan as the First Examination for the Diagnosis and Therapeutic Strategy for Acute Cholecystitis. 61
32030439 2020
34
Antibiotic use in patients with acute cholecystitis after percutaneous cholecystostomy. 61
31868860 2020
35
An Uncommon Cause of Cholecystitis. 61
31562848 2020
36
DRESS Masquerading as Acute Cholecystitis. 61
31421066 2020
37
Seasonal Variation in Acute Cholecystitis: An Analysis of Cholecystectomies Spanning Three Decades. 61
31562989 2020
38
Outcomes of Patients Treated With Upfront Cholecystostomy for Severe Acute Cholecystitis. 61
31876887 2020
39
Antibiotic Resistance in Community-Acquired Intra-Abdominal Infections: Diabetes Mellitus as a Risk Factor. 61
31441705 2020
40
Limy bile syndrome in a dog. 61
29752730 2020
41
Fluorescent Cholangiography in Laparoscopic Cholecystectomy: An Updated Canadian Experience. 61
31744398 2020
42
ERRα promotes gallbladder cancer development by enhancing the transcription of Nectin-4. 61
32030850 2020
43
Dieulafoy lesion of the gallbladder: A rare cause of hemobilia and acute pancreatitis - Case report. 61
31865234 2020
44
Clinical outcomes of acute pancreatitis in patients with cirrhosis. 61
31734110 2020
45
Luschka Ducts of the Gallbladder in Adults: Case Series Report and Review of the Medical Literature. 61
31983263 2020
46
EUS-guided gallbladder drainage: a learning curve modified by technical progress. 61
31921991 2020
47
A Rare Fatal Bile Peritonitis after Malposition of Endoscopic Ultrasound-Guided 5-Fr Naso-Gallbladder Drainage. 61
31476845 2020
48
Are the recommendations for post-operative antibiotics in patients with grade I or II acute calculous cholecystitis being applied in clinical practice? 61
31974047 2020
49
Pediatric cystic artery pseudoaneurysm embolization. 61
31982705 2020
50
Laparoscopic management of intra-hepatic gallbladder perforation. 61
30618436 2020

Variations for Cholecystitis

Expression for Cholecystitis

Search GEO for disease gene expression data for Cholecystitis.

Pathways for Cholecystitis

Pathways related to Cholecystitis according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.83 TP53 TLR4 S100A9 S100A8 MUC6 MUC5AC
2
Show member pathways
12.6 TP53 EGFR EGF CDKN2A CDH1
3
Show member pathways
12.49 TP53 EGFR EGF CDKN2A CDH1
4 12.22 TP53 F2 EGFR EGF DAPK1 CDKN2A
5
Show member pathways
12.16 TP53 F2 CAT ALB
6
Show member pathways
12.15 TP53 MUC1 EGFR EGF CDH1
7 11.77 TP53 TLR4 EGFR EGF CDH1
8 11.67 TP53 EGFR EGF CDKN2A
9 11.36 TP53 EGFR CDKN2A
10 11.18 EGFR EGF CDH1
11 11.04 EGFR EGF CDH1
12 10.96 TP53 EGFR EGF DAPK1 CDKN2A CDH1
13 10.36 MUC6 CCK
14
Show member pathways
10.03 EGFR EGF

GO Terms for Cholecystitis

Cellular components related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 10.17 TLR4 S100A9 S100A8 MUC6 MUC5AC MUC1
2 extracellular exosome GO:0070062 9.93 S100A9 S100A8 MUC5AC MUC1 HP GPT
3 extracellular region GO:0005576 9.8 S100A9 S100A8 MUC6 MUC5AC MUC1 HP
4 blood microparticle GO:0072562 9.67 HP F2 CP ALB
5 Golgi lumen GO:0005796 9.56 MUC6 MUC5AC MUC1 F2
6 extracellular space GO:0005615 9.44 S100A9 S100A8 MUC5AC MUC1 HP GPT

Biological processes related to Cholecystitis according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.99 TP53 S100A9 S100A8 DAPK1 CDKN2A CCK
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.76 TLR4 S100A9 S100A8 CAT
3 regulation of inflammatory response GO:0050727 9.75 TLR4 S100A9 S100A8
4 O-glycan processing GO:0016266 9.71 MUC6 MUC5AC MUC1
5 toll-like receptor signaling pathway GO:0002224 9.65 TLR4 S100A9 S100A8
6 positive regulation of intrinsic apoptotic signaling pathway GO:2001244 9.58 TP53 S100A9 S100A8
7 positive regulation of protein oligomerization GO:0032461 9.57 TP53 CCK
8 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 9.56 TP53 EGFR
9 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.56 S100A9 S100A8 CDKN2A CCK
10 leukocyte migration involved in inflammatory response GO:0002523 9.55 S100A9 S100A8
11 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.52 TP53 MUC1
12 negative regulation of ERBB signaling pathway GO:1901185 9.49 EGFR EGF
13 positive regulation of inflammatory response GO:0050729 9.46 TLR4 S100A9 S100A8 EGFR
14 sequestering of zinc ion GO:0032119 9.43 S100A9 S100A8
15 chemokine production GO:0032602 9.37 S100A9 S100A8
16 neutrophil aggregation GO:0070488 9.32 S100A9 S100A8
17 cellular oxidant detoxification GO:0098869 9.26 S100A9 HP CAT ALB
18 positive regulation of cell growth GO:0030307 8.92 S100A9 S100A8 F2 EGFR

Molecular functions related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.87 TP53 TLR4 EGFR DAPK1 CDH1 CAT
2 copper ion binding GO:0005507 9.43 TP53 CP ALB
3 RAGE receptor binding GO:0050786 9.37 S100A9 S100A8
4 arachidonic acid binding GO:0050544 9.16 S100A9 S100A8
5 Toll-like receptor 4 binding GO:0035662 8.96 S100A9 S100A8
6 antioxidant activity GO:0016209 8.92 S100A9 HP CAT ALB

Sources for Cholecystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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