MCID: CHL067
MIFTS: 57

Cholecystitis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Cholecystitis

MalaCards integrated aliases for Cholecystitis:

Name: Cholecystitis 12 74 52 54 43 15 71 32
Acute Cholecystitis 12 54 15 71 32
Chronic Cholecystitis 12 54 71 32
Acute and Chronic Cholecystitis 12 71
Acalculous Cholecystitis 52 71
Calculus of Gallbladder with Cholecystitis 71
Acute on Chronic Cholecystitis 12
Gallstone Cholecystitis 52
Cholecystitis, Acute 17

Classifications:



External Ids:

Disease Ontology 12 DOID:1949
ICD9CM 34 575.10
MeSH 43 D002764
NCIt 49 C34465
SNOMED-CT 67 76581006
UMLS 71 C0008325 C0085694 C0149520 more

Summaries for Cholecystitis

Disease Ontology : 12 A cholangitis that is characterized by an inflammation that is located in the gallbladder.

MalaCards based summary : Cholecystitis, also known as acute cholecystitis, is related to emphysematous cholecystitis and acalculous cholecystitis. An important gene associated with Cholecystitis is CCK (Cholecystokinin), and among its related pathways/superpathways are Innate Immune System and Gastric cancer. The drugs Ketamine and Nefopam have been mentioned in the context of this disorder. Affiliated tissues include gallbladder, liver and testes, and related phenotypes are Reduced mammosphere formation and cellular

Wikipedia : 74 Cholecystitis is inflammation of the gallbladder. Symptoms include right upper abdominal pain, nausea,... more...

Related Diseases for Cholecystitis

Diseases related to Cholecystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 883)
# Related Disease Score Top Affiliating Genes
1 emphysematous cholecystitis 34.9 GPT F2 CCK
2 acalculous cholecystitis 34.3 GPT F2 CCKAR CCK ALB
3 cholelithiasis 32.9 HP GPT CCKAR CCK ALB
4 gallbladder disease 32.5 TP53 GPT EGFR CDH1 CCKAR CCK
5 choledocholithiasis 31.7 GPT F2 ALB
6 appendicitis 31.3 TLR4 S100A9 ALB
7 acute cholangitis 31.3 MUC5AC GPT F2 ALB
8 obstructive jaundice 31.2 TLR4 GPT F2 ALB
9 cholangitis 31.2 TP53 TLR4 HP GPT F2 ALB
10 pancreatitis 31.2 TP53 CDKN2A CCKAR CCK ALB
11 typhoid fever 31.2 TLR4 GPT F2 ALB
12 peptic ulcer disease 31.1 TP53 MUC5AC CAT ALB
13 biliary tract disease 31.1 TP53 GPT F2 CCK ALB
14 acute pancreatitis 31.1 TLR4 GPT CCKAR CCK ALB
15 pyelonephritis 31.0 TLR4 GPT ALB
16 gallbladder cancer 31.0 TP53 MUC1 EGFR EGF CDKN2A CDH1
17 hepatitis a 31.0 TLR4 GPT F2 ALB
18 duodenal ulcer 31.0 TLR4 EGF CCK CAT
19 cholestasis 30.9 GPT F2 CP CCK ALB
20 bilirubin metabolic disorder 30.8 HP GPT F2 ALB
21 diverticulitis 30.8 S100A9 MUC5AC ALB
22 gastroenteritis 30.8 CP CDH1 CAT ALB
23 cholangitis, primary sclerosing 30.7 TLR4 GPT F2 ALB
24 ascending cholangitis 30.7 GPT F2 ALB
25 gastritis 30.7 TP53 TLR4 MUC6 CDH1 CAT
26 exanthem 30.7 GPT F2 EGFR ALB
27 cystitis 30.6 TP53 TLR4 EGF CDH1
28 aspiration pneumonia 30.6 GPT F2 ALB
29 endocarditis 30.6 F2 CAT ALB
30 pericardial effusion 30.6 GPT F2 ALB
31 paralytic ileus 30.6 GPT F2 ALB
32 schistosomiasis 30.5 TP53 GPT F2 ALB
33 acute kidney failure 30.5 HP GPT F2 EGF CAT ALB
34 sclerosing cholangitis 30.5 TP53 TLR4 HP GPT F2 ALB
35 fascioliasis 30.5 GPT CP ALB
36 salmonellosis 30.5 TLR4 GPT ALB
37 respiratory failure 30.4 TLR4 MUC5AC GPT F2 CAT ALB
38 hepatic infarction 30.4 GPT F2 ALB
39 hepatic coma 30.4 GPT F2 ALB
40 portal hypertension 30.4 TLR4 GPT F2 ALB
41 dengue hemorrhagic fever 30.4 GPT F2 ALB
42 crohn's disease 30.4 TLR4 S100A9 HP ALB
43 hepatorenal syndrome 30.4 GPT F2 ALB
44 constipation 30.4 GPT CCK CAT ALB
45 hepatitis e 30.3 GPT F2 ALB
46 intestinal perforation 30.3 TLR4 GPT ALB
47 papillary adenocarcinoma 30.3 TP53 MUC1 CDH1
48 hydrops of gallbladder 30.3 GPT CP ALB
49 diarrhea 30.3 TLR4 GPT EGFR CDH1 CCK ALB
50 intrahepatic cholangiocarcinoma 30.3 TP53 MUC5AC MUC1 EGFR CDH1 ALB

Comorbidity relations with Cholecystitis via Phenotypic Disease Network (PDN): (show all 11)


Acute Cystitis Acute Pancreatitis
Cholangitis Cholestasis
Deficiency Anemia Esophagitis
Familial Atrial Fibrillation Heart Disease
Hypertension, Essential Paralytic Ileus
Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Cholecystitis:



Diseases related to Cholecystitis

Symptoms & Phenotypes for Cholecystitis

GenomeRNAi Phenotypes related to Cholecystitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 ALB CCKAR CDH1 EGFR KRT18 MUC5AC

MGI Mouse Phenotypes related to Cholecystitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.22 ALB CAT CCKAR CDH1 CDKN2A CP
2 homeostasis/metabolism MP:0005376 10.2 ALB CAT CCK CCKAR CDH1 CDKN2A
3 digestive/alimentary MP:0005381 10.07 ALB CCKAR CDH1 CDKN2A EGF EGFR
4 immune system MP:0005387 10.03 ALB CDH1 CDKN2A CP EGF EGFR
5 liver/biliary system MP:0005370 9.81 ALB CCKAR CDKN2A CP EGFR HP
6 neoplasm MP:0002006 9.56 ALB CAT CDH1 CDKN2A EGFR HP
7 renal/urinary system MP:0005367 9.23 ALB CCK CCKAR DAPK1 EGFR HP

Drugs & Therapeutics for Cholecystitis

Drugs for Cholecystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 150)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
2
Nefopam Approved, Investigational Phase 4 13669-70-0
3
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
4
Metronidazole Approved Phase 4 443-48-1 4173
5
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
6
Ceftriaxone Approved Phase 4 73384-59-5 5361919 5479530
7
Tigecycline Approved Phase 4 220620-09-7 5282044
8 Hydrotalcite Approved, Experimental, Investigational Phase 4 12304-65-3
9
Sucralfate Approved Phase 4 54182-58-0
10
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
11
Remifentanil Approved Phase 4 132875-61-7 60815
12
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
13
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
14
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
15
tannic acid Approved Phase 4 1401-55-4
16
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337
17
Fosaprepitant Approved Phase 4 172673-20-0 219090
18
Palonosetron Approved, Investigational Phase 4 135729-56-5, 119904-90-4 148211
19
Aprepitant Approved, Investigational Phase 4 170729-80-3 6918365 151165
20
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
21
Sultamicillin Approved, Investigational Phase 4 76497-13-7
22
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
23
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
24
Aspartic acid Approved, Nutraceutical Phase 4 56-84-8 5960
25 Hemostatics Phase 4
26 Anesthetics, Intravenous Phase 4
27 Excitatory Amino Acid Antagonists Phase 4
28 Anesthetics, Dissociative Phase 4
29 Anti-Bacterial Agents Phase 4
30 Anti-Infective Agents Phase 4
31 Vitamins Phase 4
32 Antiprotozoal Agents Phase 4
33 Antiparasitic Agents Phase 4
34 Trace Elements Phase 4
35 Antioxidants Phase 4
36 Nutrients Phase 4
37 Micronutrients Phase 4
38 Protective Agents Phase 4
39 Analgesics, Opioid Phase 4
40 Antacids Phase 4
41 Anti-Ulcer Agents Phase 4
42 Adrenergic alpha-Agonists Phase 4
43 Hypnotics and Sedatives Phase 4
44 Adrenergic Agents Phase 4
45 Adrenergic Agonists Phase 4
46 Cyclooxygenase 2 Inhibitors Phase 4
47 Cyclooxygenase Inhibitors Phase 4
48 Antirheumatic Agents Phase 4
49 Anti-Inflammatory Agents, Non-Steroidal Phase 4
50 Ulipristal acetate Phase 4 126784-99-4

Interventional clinical trials:

(show top 50) (show all 201)
# Name Status NCT ID Phase Drugs
1 THE USE OF FLOSEAL GELATIN MATRIX FOR THE HAEMOSTASIS DURING LAPAROSCOPIC CHOLECYSTECTOMY FOR ACUTE CHOLECYSTITIS; EFFICACY AND SAFETY EVALUATED IN A MULTICENTER, PROSPECTIVE, OPEN LABEL TRIAL WITH AN HISTORICAL CONTROL GROUP. (G.L.A. STUDY: GELATIN Matrix in Laparoscopic Cholecystectomy for Acute Cholecystitis) Unknown status NCT01126281 Phase 4
2 DOLCE Study: Day-care Versus Overnight-stay Laparoscopic Cholecystectomy Randomized, Controlled Trial Unknown status NCT01052727 Phase 4
3 Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia Unknown status NCT02493231 Phase 4 Nefopam;Ketamine;Saline
4 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy Due to Acute Cholecystitis. Is it Necessary? Completed NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
5 A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
6 Studie Naar De Effectiviteit Van Ursodeoxycholzuur Ter Preventie Van Galsteen-Gerelateerde Klachten Bij patiënten in Afwachting Van Een Cholecystectomie Completed NCT00161083 Phase 4 ursodeoxycholic acid
7 The Role of a Single Oral Dose (2g) of Vitamin C in Reducing Intensity of Pain and Opioids Consumption in Patients Undergoing Laparoscopic Cholecystectomy. A Randomized, Double-blinded, Placebo-controlled Study Completed NCT01322061 Phase 4 Ascorbic Acid
8 A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment: Randomized Trial Completed NCT03635372 Phase 4 Alginate;Sucralfate;Hydrotalcite
9 Opioid-free Total Intravenous Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy; Comparison With Propofol, Remifentanil Infusions Completed NCT01833819 Phase 4 Dexmedetomidine and lidocaine;Remifentanil
10 Pain Post Abdominal Laparoscopy Prevention With Arcoxia Completed NCT00565682 Phase 4 etoricoxib 120 mg
11 Covered Versus Uncovered Metal Stents for Management of Distal Malignant Biliary Obstruction? Results of a Randomized Prospective Study. Completed NCT00280709 Phase 4
12 A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
13 Effect of Deep Versus Moderate Neuromuscular Blockade on Peak Airway Pressures During Elective Laparoscopic Surgery Completed NCT02812186 Phase 4 Rocuronium
14 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Randomized Multi-center Study Completed NCT01744847 Phase 4
15 Multi-Port vs. Single-port Cholecystectomy Completed NCT01104727 Phase 4
16 COMPARATIVE STUDY BETWEEN PALONOSETRON AND FOSAPREPITANT IN THE PROFILAXIA OF POSTOPERATIVE NAUSEA AND VOMITING IN WOMEN SUBMITTED TO VIDEOLAPAROSCOPIC COLECISTECTOMIES Recruiting NCT03586817 Phase 4 Palonosetron;Fosaprepitant
17 Is an Antibiotic Prescription Required After Laparoscopic Cholecystectomy for Acute Calculous Cholecystitis? Not yet recruiting NCT04290104 Phase 4 1gr oral ampicillin/sulbactam group
18 The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders Terminated NCT02472509 Phase 4 Ursodeoxycholic Acid
19 Use of IV Acetaminophen Intraoperatively in Obese Patients at Risk for Obstructive Sleep Apnea Undergoing Laparoscopic Cholecystectomy Withdrawn NCT02056678 Phase 4 acetaminophen, IV preparation
20 Drainage is Not Necessary Procedure After Laparoscopic Cholecystectomy Due to Severe Acute Cholecystitis Unknown status NCT01625247 Phase 3
21 Single Port Access Cholecystectomy Versus Standard Laparoscopic Cholecystectomy - Randomized Study Unknown status NCT00904865 Phase 2, Phase 3
22 Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy = ACDC-study Completed NCT00447304 Phase 3 moxifloxacin
23 Endosonography-guided Gallbladder Drainage (EGBD) Versus Percutaneous Cholecystostomy (PC) in Patients Suffering From Acute Cholecystitis That Are Unsuitable for Surgery. A Randomized Controlled Trial. Completed NCT02212717 Phase 2, Phase 3
24 Piperacllin Versus Placebo in Patients Undergoing Surgery for Acute Cholecystitis Completed NCT02619149 Phase 3 Piperacillin-tazobactam combination product;Saline solution
25 Antibiotic Treatment Versus no Antibiotics in the Postoperative Acute Cholecystitis Low and Moderately Severe Completed NCT01015417 Phase 3 Amoxicillin clavulanic acid
26 A Multicenter, Double-Blind, Randomized, Phase 3 Study of Doripenem Versus Comparator Antibiotic in the Treatment of Complicated Intra-Abdominal Infections Completed NCT00210938 Phase 3 Doripenem
27 A Multicenter, Double-Blind, Randomized, Phase 3 Study of Doripenem Versus Comparator Antibiotic in the Treatment of Complicated Intra-Abdominal Infections Completed NCT00229060 Phase 3 doripenem
28 Dexamethasone Improves Postoperative Symptoms in Patients Undergoing Elective Laparoscopic Cholecystectomy: A Randomised Clinical Trial. Completed NCT01030614 Phase 3 Dexamethasone;placebo
29 Prospective Randomized Clinical Trial Comparing Single Incision Laparoscopic Surgery vs Flexible Single Incision Surgery on Cholecystectomy Completed NCT01558414 Phase 3
30 Residual Gastric Volume Measured by Upper Digestive Endoscopy 2h After the Ingestion of a Beverage Containing Carbohydrates Plus Whey Protein. A Controlled, Randomized Clinical Trial Completed NCT01828645 Phase 2, Phase 3
31 An Expertise-based Randomized Controlled Trial Comparing Minilaparotomy Cholecystectomy and Laparoscopic Cholecystectomy Completed NCT00370344 Phase 2, Phase 3
32 Prospective Study for the Effects of Biphenyl Dimethyl Dicarboxylate and Ursodeoxycolic Acid Therapy on Liver Function and Quality of Life After Laparoscopic Cholecystectomy Recruiting NCT03578055 Phase 3 BDD with UDCA;Placebo
33 Does it Make Sense to Give Postoperative Antibiotics to Patients With an Uncomplicated Acute Cholecystitis Completed NCT00323648 Phase 2 Whether or not giving postoperatively antibiotics to patients with an uncomplicated acute cholecystitis
34 Antibiotic Prophylaxis for ERCP: a Comparison of Intravenous Ceftriaxone With Intravenous Moxifloxacin in the Prophylaxis of Cholangitis Completed NCT02098486 Phase 2 Moxifloxacin;ceftriaxone
35 Efficacy and Safety of Dengue Vaccine in Healthy Children Aged 4 to 11 Years in Thailand Completed NCT00842530 Phase 2
36 MANAGEMENT OF THE PATIENT WITH ACUTE ABDOMEN SUBMITTED TO URGENT ABDOMINAL SURGERY: a Pilot Randomized Multicentre Study Completed NCT01911702 Phase 2
37 Pilot Study to Assess Safety and Efficacy Of An Endoscopic Bipolar Radiofrequency Probe (EndoHPB) In the Management of Unresectable Bile Duct and Pancreatic Cancer Unknown status NCT02042859 Phase 1
38 Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy Sub-Study Completed NCT02070627 Phase 1 Indocyanine Green (ICG)
39 Pilot Study to Assess the Safety and Pharmacokinetics of 70-150μm Drug Eluting Beads Loaded With Irinotecan (DEBIRI) in the Treatment of Hepatic Colorectal Metastases Completed NCT02350400 Phase 1
40 Prospective Single-Arm Pilot Study for CT-Guided, Temporary Celiac Ganglion Block as a Test Before Celiac Ganglion Resection for Dysautonomia-Related Bowel Dysmotility Recruiting NCT04121338 Phase 1 Liposomal bupivacaine
41 Phase I Clinical Trial on Intra-tumoral Ipilimumab Plus Intravenous Nivolumab Following the Resection of Recurrent Glioblastoma Recruiting NCT03233152 Phase 1 Ipilimumab (YervoyTM, 50 mg/10 mL solution);Nivolumab (OpdivoTM, 40 mg/4mL solution)
42 Laparoscopic Cholecystectomy Using Transvaginal Endoscopic Assistance Withdrawn NCT00815438 Phase 1
43 Percutaneous Drainage in a Setting of Acute Cholecystitis Severity Grade III and Correlation With Clinical Outcomes Unknown status NCT03087747
44 Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study Unknown status NCT02130245
45 Laparoscopic Cholecystectomy for Management of Acute Calculous Cholecystitis Within and After 3 Days of Disease Onset Unknown status NCT03477253
46 Transient ECG Changes in Patients With Acute Biliary Disease Unknown status NCT01706068
47 A Comparison of Robot-assisted Single Site and Laparoscopic Single-incision Cholecystectomy for Benign Gallbladder Unknown status NCT02485392
48 Prediction of Postoperative Pain by Injection Pain of Propofol Unknown status NCT03021447
49 Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy; a A Prospective Randomized Controlled Trial Unknown status NCT02553551 Vitamin C;Placebo
50 Efficacy of Hemopatch in Reducing of Postoperative Bleeding After Laparoscopic Cholecystectomy: Prosective and Multicenter Study Unknown status NCT02777307

Search NIH Clinical Center for Cholecystitis

Cochrane evidence based reviews: cholecystitis

Genetic Tests for Cholecystitis

Anatomical Context for Cholecystitis

The Foundational Model of Anatomy Ontology organs/tissues related to Cholecystitis:

19
Gallbladder

MalaCards organs/tissues related to Cholecystitis:

40
Liver, Testes, Pancreas, Heart, Colon, Lung, Kidney

Publications for Cholecystitis

Articles related to Cholecystitis:

(show top 50) (show all 14039)
# Title Authors PMID Year
1
Gallbladder carcinoma manifesting as acute cholecystitis: clinical and computed tomographic features. 61 54
19744453 2009
2
Acute transient hepatocellular injury in cholelithiasis and cholecystitis without evidence of choledocholithiasis. 54 61
19673021 2009
3
Usefulness of fatty meal-stimulated cholescintigraphy in the diagnosis and treatment of chronic acalculous cholecystitis. 61 54
19225936 2009
4
Liver enzyme elevation and normal pulmonary function in an adult with a declining forced expiratory volume in 1 second. 54 61
18534093 2008
5
Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder. 54 61
18182589 2008
6
Effect of sequential administration of an opioid and cholecystokinin on gallbladder ejection fraction: brief communication. 61 54
16954554 2006
7
Stimulation with fatty meal (Lipomul) to assess gallbladder emptying in children with chronic acalculous cholecystitis. 54 61
12883305 2003
8
Bradykinin B2 receptors mediate contraction in the normal and inflamed human gallbladder in vitro. 54 61
12851878 2003
9
Influence of cholecystitis state on pharmacological response to cholecystokinin of isolated human gallbladder with gallstones. 54 61
12772786 2003
10
Gallbladder ejection fraction: an accurate evaluation of symptomatic acalculous gallbladder disease. 61 54
12872903 2003
11
Mechanisms of impaired gallbladder contractile response in chronic acalculous cholecystitis. 54 61
12022997 2002
12
Cholecystokinin cholescintigraphy: victim of its own success? 61 54
10616884 1999
13
Chronic acalculous cholecystitis: reproduction of pain with cholecystokinin and relief of symptoms with cholecystectomy. 54 61
10388344 1999
14
The clinical utility of quantitative cholescintigraphy: the significance of gallbladder dysfunction. 54 61
9596151 1998
15
Acute cholecystitis in AIDS patients: correlation of Tc-99m hepatobiliary scintigraphy with histopathologic laboratory findings and CD4 counts. 61 54
9554194 1998
16
Pharmacologic intervention for the diagnosis of acute cholecystitis: cholecystokinin pretreatment or morphine, or both? 61 54
9098218 1997
17
Cholecystokinin and morphine pharmacological intervention during 99mTc-HIDA cholescintigraphy: a rational approach. 61 54
8623048 1996
18
Abnormal gallbladder nuclear ejection fraction predicts success of cholecystectomy in patients with biliary dyskinesia. 54 61
8273847 1993
19
Cholecystokinin cholescintigraphy: detection of abnormal gallbladder motor function in patients with chronic acalculous gallbladder disease. 54 61
1880571 1991
20
[The blood level of cobalamin as an indicator of the functional status of the liver in jaundice of different etiologies]. 54 61
1721943 1991
21
Chronic right upper quadrant pain without gallstones: does HIDA scan predict outcome after cholecystectomy? 61 54
2375327 1990
22
[Sonographic criteria of acute acalculous cholecystitis.Critical observation of the clinical records of sedated, ventilated and parenterally nourished patients]. 54 61
2121670 1990
23
Cholecystokinin sonography: lack of utility in diagnosis of acute acalculous cholecystitis. 54 61
2183285 1990
24
Laparoscopic management of gall bladder perforation secondary to typhoid-induced acalculous cholecystitis: A rare entity. 61
31793452 2020
25
Concomitant laparoscopic cholecystectomy and antegrade wire, rendezvous cannulation of the biliary tree may reduce post-ERCP pancreatitis events. 61
31489502 2020
26
Agenesis of the gall bladder, an unexpected finding during laparoscopy; case report. 61
32461806 2020
27
Comparison of laparoscopic cholecystectomy and delayed laparoscopic cholecystectomy in aged acute calculous cholecystitis: a cohort study. 61
31463722 2020
28
Identification of a new genetic variant associated with cholecystitis: A multicenter genome-wide association study. 61
32118827 2020
29
Early cholecystectomy (≤ 8 weeks) following percutaneous cholecystostomy tube placement is associated with higher morbidity. 61
31372890 2020
30
Early cholecystectomy (< 72 h) is associated with lower rate of complications and bile duct injury: a study of 109,862 cholecystectomies in the state of New York. 61
31376010 2020
31
Kidney-Sparing Surgery for Renal Subcapsular Abscess Caused by Staphylococcus pseudintermedius in a Dog. 61
32412340 2020
32
Cholecystitis on gallbladder duplication: A case report and literature review. 61
32563831 2020
33
Effectiveness of near-infrared fluorescent cholangiography in the identification of cystic duct-common hepatic duct anatomy in comparison to magnetic resonance cholangio-pancreatography: a preliminary study. 61
31598878 2020
34
An Important Gallbladder Pathology Mimicking Gallbladder Carcinoma: Xanthogranulomatous Cholecystitis: A Single Tertiary Center Experience. 61
32187090 2020
35
Ventriculoperitoneal shunt malfunction due to chronic cholecystitis: A case report. 61
32569180 2020
36
True single-port cholecystectomy with ICG cholangiography through a single 15-mm trocar using the new surgical platform "symphonX": first human case study with a commercially available device. 61
31659506 2020
37
Acute cholecystitis and residual choledocholithiasis in a situs inversus patient, successful laparoscopic approach and ERCP a case report from Ecuador. 61
32426127 2020
38
Acute cholecystitis during COVID-19 pandemic: a multisocietary position statement. 61
32513287 2020
39
Abdominal Surgery in Patients with a Ventricular Assist Device: A Single Center Experience in Israel. 61
32558443 2020
40
Partially Cystic Lumbar Schwannoma with Atypical Histopathologic Features. 61
32251817 2020
41
A patient with cystic duct remnant calculus treated by laparoscopic surgery combined with near-infrared fluorescence cholangiography. 61
32577857 2020
42
INTRAOPERATIVE CHOLANGIOGRAPHY DURING CHOLECYSTECTOMY RESULTS IN LOW EXPOSURE TO RADIATION: A RETROSPECTIVE COHORT STUDY. 61
31730694 2020
43
An alternative percutaneous technique for gallbladder drainage using lumen-apposing metal stents. 61
31392512 2020
44
Antibiotics in the Biliary Tract: A Review of the Pharmacokinetics and Clinical Outcomes of Antibiotics Penetrating the Bile and Gallbladder Wall. 61
32485056 2020
45
Remnant Cystic Duct Disease After Cholecystectomy: A Case Series. 61
32496345 2020
46
A metagenomic study of biliary microbiome change along the cholecystitis-carcinoma sequence. 61
32526082 2020
47
Timing of cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis: a nationwide inpatient database study. 61
31732466 2020
48
Gallstone Disease and Microbiome. 61
32498344 2020
49
Utility of ultrasound after a negative CT abdomen and pelvis in the emergency department. 61
32563722 2020
50
Xanthogranulomatous Cholecystitis: Is Surgery Difficult? Is Laparoscopic Surgery Recommended? 61
32559394 2020

Variations for Cholecystitis

Expression for Cholecystitis

Search GEO for disease gene expression data for Cholecystitis.

Pathways for Cholecystitis

Pathways related to Cholecystitis according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.88 TP53 TLR4 S100A9 MUC6 MUC5AC MUC1
2
Show member pathways
12.6 TP53 EGFR EGF CDKN2A CDH1
3
Show member pathways
12.49 TP53 EGFR EGF CDKN2A CDH1
4
Show member pathways
12.27 TLR4 KRT18 EGFR CDH1
5
Show member pathways
12.23 TP53 MUC1 EGFR EGF CDH1
6 12.22 TP53 F2 EGFR EGF DAPK1 CDKN2A
7
Show member pathways
12.16 TP53 F2 CAT ALB
8
Show member pathways
12.11 MUC1 EGFR EGF CDH1
9 11.77 TP53 TLR4 EGFR EGF CDH1
10 11.6 TP53 EGFR EGF CDKN2A
11 11.36 TP53 EGFR CDKN2A
12 11.18 EGFR EGF CDH1
13 10.99 EGFR EGF CDH1
14 10.96 TP53 EGFR EGF DAPK1 CDKN2A CDH1
15 10.36 MUC6 CCK
16
Show member pathways
10.03 EGFR EGF

GO Terms for Cholecystitis

Cellular components related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 10.18 TLR4 S100A9 MUC6 MUC5AC MUC1 F2
2 extracellular exosome GO:0070062 9.93 S100A9 MUC5AC MUC1 KRT18 HP GPT
3 extracellular region GO:0005576 9.77 S100A9 MUC6 MUC5AC MUC1 HP F2
4 blood microparticle GO:0072562 9.62 HP F2 CP ALB
5 Golgi lumen GO:0005796 9.56 MUC6 MUC5AC MUC1 F2
6 extracellular space GO:0005615 9.4 S100A9 MUC5AC MUC1 HP GPT F2

Biological processes related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell growth GO:0030307 9.58 S100A9 F2 EGFR
2 O-glycan processing GO:0016266 9.43 MUC6 MUC5AC MUC1
3 negative regulation of apoptotic process GO:0043066 9.43 TP53 KRT18 EGFR DAPK1 CAT ALB
4 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 9.37 TP53 EGFR
5 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.32 TP53 MUC1
6 negative regulation of ERBB signaling pathway GO:1901185 9.16 EGFR EGF
7 cellular oxidant detoxification GO:0098869 8.92 S100A9 HP CAT ALB

Molecular functions related to Cholecystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 copper ion binding GO:0005507 9.13 TP53 CP ALB
2 antioxidant activity GO:0016209 8.92 S100A9 HP CAT ALB

Sources for Cholecystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
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43 MeSH
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50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
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61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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