MCID: CHL013
MIFTS: 40

Cholecystolithiasis

Categories: Gastrointestinal diseases

Aliases & Classifications for Cholecystolithiasis

MalaCards integrated aliases for Cholecystolithiasis:

Name: Cholecystolithiasis 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11151
MeSH 44 D041761
NCIt 50 C34443
UMLS 73 C0947622

Summaries for Cholecystolithiasis

MalaCards based summary : Cholecystolithiasis is related to choledocholithiasis and cholecystitis. An important gene associated with Cholecystolithiasis is UVRAG (UV Radiation Resistance Associated), and among its related pathways/superpathways are Immune response IFN gamma signaling pathway and Wnt / Hedgehog / Notch. The drugs Benzocaine and Propofol have been mentioned in the context of this disorder. Affiliated tissues include skin, pancreas and liver.

Wikipedia : 76 A gallstone is a stone formed within the gallbladder out of bile components. The term cholelithiasis may... more...

Related Diseases for Cholecystolithiasis

Diseases related to Cholecystolithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 52)
# Related Disease Score Top Affiliating Genes
1 choledocholithiasis 30.4 ABCB4 STK10
2 cholecystitis 29.9 ABCB4 CCK
3 gallbladder disease 1 10.9
4 kidney hypertrophy 10.6 CTGF TGFB1
5 stiff skin syndrome 10.6 CTGF TGFB1
6 gingival disease 10.5 CTGF TGFB1
7 scleroderma, familial progressive 10.5 BMP6 CTGF
8 localized scleroderma 10.5 CTGF TGFB1
9 nephrogenic systemic fibrosis 10.5 CTGF TGFB1
10 ureteral disease 10.5 CTGF TGFB1
11 sialolithiasis 10.5 CTGF TGFB1
12 tuberculoid leprosy 10.5 BMP6 TGFB1
13 nephrosclerosis 10.5 CTGF TGFB1
14 hypertrophic scars 10.5 BMP6 TGFB1
15 ocular cicatricial pemphigoid 10.5 CTGF TGFB1
16 dupuytren contracture 10.5 BMP6 TGFB1
17 vitreoretinopathy, neovascular inflammatory 10.4 CTGF TGFB1
18 urinary tract obstruction 10.4 CTGF TGFB1
19 carpal tunnel syndrome 10.3 CTGF TGFB1
20 ascending cholangitis 10.3 CCK TGFB1
21 crouzon syndrome 10.3 BMP6 TGFB1
22 gingival overgrowth 10.3 CTGF TGFB1
23 rasmussen encephalitis 10.2 BMP6 CCK
24 biliary dyskinesia 10.2 CCK STK10
25 ureteral obstruction 10.2 BMP6 TGFB1
26 common bile duct disease 10.2 CCK STK10
27 biliary atresia 10.2 CTGF TGFB1
28 microvascular complications of diabetes 3 10.1 BMP6 CTGF TGFB1
29 renal fibrosis 10.1 BMP6 CTGF TGFB1
30 gingival fibromatosis 10.1 CTGF TGFB1
31 pulmonary fibrosis, idiopathic 10.1 BMP6 CTGF TGFB1
32 idiopathic interstitial pneumonia 10.0 CTGF TGFB1
33 bile duct disease 9.9 ABCB4 CCK
34 biliary tract disease 9.9 ABCB4 CCK
35 liver disease 9.9
36 duodenitis 9.9
37 cholelithiasis 9.8 ABCB4 CCK
38 dubin-johnson syndrome 9.8
39 aging 9.8
40 helicobacter pylori infection 9.8
41 hepatitis 9.8
42 liver cirrhosis 9.8
43 mucositis 9.8
44 ascending colon cancer 9.8
45 dyspepsia 9.8
46 bile duct carcinoma 9.8
47 pancreatitis 9.8
48 situs inversus 9.8
49 dextrocardia with situs inversus 9.8
50 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.8

Graphical network of the top 20 diseases related to Cholecystolithiasis:



Diseases related to Cholecystolithiasis

Symptoms & Phenotypes for Cholecystolithiasis

Drugs & Therapeutics for Cholecystolithiasis

Drugs for Cholecystolithiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 236)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
2
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
3
Remifentanil Approved Phase 4 132875-61-7 60815
4
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
5
Droperidol Approved, Vet_approved Phase 4 548-73-2 3168
6
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
7
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
8
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
9
Flurbiprofen Approved, Investigational Phase 4 5104-49-4 3394
10
Ropivacaine Approved Phase 4,Not Applicable 84057-95-4 71273 175805
11
Tramadol Approved, Investigational Phase 4,Not Applicable 27203-92-5 33741
12
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
13
Acetaminophen Approved Phase 4 103-90-2 1983
14
Clonidine Approved Phase 4 4205-90-7 2803
15 Nefopam Approved, Investigational Phase 4 13669-70-0
16
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
17
Ursodeoxycholic acid Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 128-13-2 31401
18
Ondansetron Approved Phase 4 99614-02-5 4595
19
Bupivacaine Approved, Investigational Phase 4,Not Applicable 2180-92-9, 38396-39-3 2474
20
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
21
Granisetron Approved, Investigational Phase 4 109889-09-0 3510
22
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
23
Ephedrine Approved Phase 4 299-42-3 9294
24
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
25
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
26
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
27
Morphine Approved, Investigational Phase 4 57-27-2 5288826
28
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
29
Pseudoephedrine Approved Phase 4 90-82-4 7028
30
Etomidate Approved Phase 4 33125-97-2 36339 667484
31
Meperidine Approved Phase 4,Not Applicable 57-42-1 4058
32
Midazolam Approved, Illicit Phase 4,Not Applicable 59467-70-8 4192
33
chenodeoxycholic acid Approved Phase 4,Phase 2 474-25-9 10133
34
Tauroursodeoxycholic acid Approved, Investigational Phase 4 14605-22-2 12443252
35
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
36
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
37
Sulbactam Approved Phase 4 68373-14-8
38 Sultamicillin Approved, Investigational Phase 4 76497-13-7
39 tannic acid Approved, Nutraceutical Phase 4
40 Analgesics Phase 4,Not Applicable
41 Analgesics, Opioid Phase 4,Not Applicable
42 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
43 Anesthetics, General Phase 4,Not Applicable
44 Anesthetics, Intravenous Phase 4
45 Central Nervous System Depressants Phase 4,Phase 1,Not Applicable
46 Hypnotics and Sedatives Phase 4,Phase 1
47 Narcotics Phase 4,Not Applicable
48 Peripheral Nervous System Agents Phase 4,Phase 1,Not Applicable
49 Adjuvants, Anesthesia Phase 4
50 Anesthetics, Dissociative Phase 4

Interventional clinical trials:

(show top 50) (show all 281)
# Name Status NCT ID Phase Drugs
1 Closed-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy Unknown status NCT02114437 Phase 4
2 Optimal Multimodal Analgesia in Laparoscopic Cholecystectomy Unknown status NCT00209885 Phase 4 Gabapentin;S-ketamine;Lidocaine;Droperidol
3 Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies Unknown status NCT00792389 Phase 4
4 Laparo-endoscopic Single Site (LESS) Cholecystectomy Versus Standard LAP-CHOLE Unknown status NCT01339325 Phase 4
5 Day-care Versus Overnight-stay Laparoscopic Cholecystectomy Randomized Controlled Trial. Unknown status NCT01052727 Phase 4
6 Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla Unknown status NCT02703077 Phase 4
7 Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial Unknown status NCT02300480 Phase 4
8 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis Unknown status NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
9 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
10 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4 ursodeoxycholic acid
11 Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy Completed NCT01211743 Phase 4
12 Dual-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy (DLTCI) Completed NCT02116985 Phase 4
13 Effect of Acupuncture on Postoperative Nausea and Vomiting Completed NCT00674713 Phase 4 Ondansetron;Physiological saline solution;Ondansetron;Physiological saline solution
14 Robotic Assisted Versus Laparoscopic Cholecystectomy - Outcome and Cost Analyses of a Case-Matched Control Study Completed NCT00562900 Phase 4
15 Endovenous Lidocaine and Serum Cytokines Concentration Completed NCT02363699 Phase 4 Lidocaine;Saline solution
16 Pain Reduction After Cholecystectomy Completed NCT01199406 Phase 4 Levobupivacaine
17 Granisetron Effect on Hemodynamic Changes in Laparoscopic Cholecystectomy Completed NCT03180229 Phase 4 Granisetron 1 Mg/mL Intravenous Solution
18 Multi-Port Versus Single-port Cholecystectomy Completed NCT01104727 Phase 4
19 Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy Completed NCT02327923 Phase 4 Lidocaine;Esmolol;Paracetamol;Lidocaine;Propofol;Fentanyl;Vecuronium;Atropine;Ephedrine;Morphine;Ketorolac;Ondansetron;Bupivacaine;Tramadol;Neostigmine;Glycopyrrolate
20 Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction Completed NCT02909595 Phase 4
21 Minilaparoscopic Versus Conventional Laparoscopic Cholecystectomy Completed NCT01397565 Phase 4
22 Levobupivacaine During Cholecystectomy Completed NCT00836316 Phase 4 levobupivacaine
23 LaGRA Trial in Laparoscopic Cholecystectomy Completed NCT03394807 Phase 4 Levobupivacaine;Placebo
24 Cholecyst- Versus Cystic Duct Cholangiography During Laparoscopic Cholecystectomy Completed NCT01103570 Phase 4
25 Effect of Intraperitoneal and Intravenous Lignocaine on Pain Relief Following Laparoscopic Cholecystectomy Completed NCT01717222 Phase 4 Intraperitoneal Lignocaine;Intravenous Lignocaine
26 Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain Completed NCT03265223 Phase 4 0.2% ropivacaine
27 Effect of Rowachol on Prevention of Postcholecystectomy Syndrome Completed NCT01765465 Phase 4 Rowachol;Placebo
28 Etomidate vs. Midazolam for Sedation During ERCP Completed NCT02027311 Phase 4 Etomidate;Midazolam;Meperidine
29 Contrastive Study for Minimally Invasive Cholecystolithotomy With Gallbladder Reservation and Laparoscopic Cholecystectomy Recruiting NCT01822262 Phase 4
30 The Discovery of the Double Sphincter in Gallbladder Recruiting NCT01998451 Phase 4 Tauroursodeoxycholic acid
31 Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy Recruiting NCT03168555 Phase 4 chenodeoxycholic acid
32 Antibiotic Prophylaxis in Laparoscopic Cholecystectomy Suspended NCT01888822 Phase 4 Ciprofloxacin;Ampicillin-sulbactam;Placebo
33 The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders Terminated NCT02472509 Phase 4 Ursodeoxycholic Acid
34 Lithotripsy for the Treatment of Gallstones Terminated NCT00042549 Phase 4 ursodiol
35 Outcome of IV Acetaminophen Use in Laparoscopic Cholecystectomies in Patients at Risk of OSA Withdrawn NCT02056678 Phase 4 acetaminophen, IV preparation
36 Effect of Saline Irrigation to DEcrease Rate Of Residual Common Bile Duct Stones Unknown status NCT01425177 Phase 3
37 Safety and Efficacy Study of Transumbilical Laparoendoscopic Single Site Cholecystectomy Unknown status NCT01383031 Phase 2, Phase 3
38 Single Port Access (SPA) Cholecystectomy Versus Standard Laparoscopic Cholecystectomy Unknown status NCT00904865 Phase 2, Phase 3
39 Renalof in the Treatment of Elderly Patients With Gallstones Completed NCT01099319 Phase 3
40 Compare Combined Sphincterotomy and Balloon Dilation (ESBD) Versus Standard Sphincterotomy (ES) in Removing Biliary Stones Completed NCT00164853 Phase 3
41 Laparoscopic Cholecystectomy vs Hybrid Natural Orifice Translumenal Surgery Completed NCT00835250 Phase 3
42 Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease Completed NCT00370344 Phase 2, Phase 3
43 Single Incision Laparoscopic Surgery vs Flexible Single Incision Surgery for Cholecystectomy Completed NCT01558414 Phase 3
44 Digital SpyGlass Confirmed Common Bile Duct Stones Clearance Without Fluoroscopy Completed NCT02967926 Phase 3
45 Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy Completed NCT00447304 Phase 3 moxifloxacin
46 Pentoxifylline Treatment in Acute Pancreatitis (AP) Completed NCT02487225 Phase 3 Pentoxifylline;Placebo
47 Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones Completed NCT02592811 Phase 3
48 A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383) Completed NCT02550288 Phase 3 Ezetimibe 10 mg;Atorvastatin 10 mg;Placebo for Ezetimibe 10 mg tablet;Placebo for Atorvastatin 10 mg capsule
49 A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384) Completed NCT02460159 Phase 3 EZ 10 mg/Atorva 20 mg FDC;EZ 10 mg/Atorva 10 mg FDC
50 A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832) Completed NCT02741245 Phase 3 Ezetimibe 10 mg;Rosuvastatin 2.5 mg;Placebo for Ezetimibe;Placebo for Rosuvastatin

Search NIH Clinical Center for Cholecystolithiasis

Cochrane evidence based reviews: cholecystolithiasis

Genetic Tests for Cholecystolithiasis

Anatomical Context for Cholecystolithiasis

MalaCards organs/tissues related to Cholecystolithiasis:

41
Skin, Pancreas, Liver, Kidney, Bone, Colon

Publications for Cholecystolithiasis

Articles related to Cholecystolithiasis:

(show top 50) (show all 89)
# Title Authors Year
1
Cavernous Transformation of the Portal Vein Secondary to Cholecystolithiasis. ( 29786056 )
2018
2
Minilaparoscopic versus single incision cholecystectomy for the treatment of cholecystolithiasis: a meta-analysis and systematic review. ( 28830403 )
2017
3
Minimally Invasive Cholecystolithotomy to Treat Cholecystolithiasis in Children: A Single-center Experience With 23 Cases. ( 28614174 )
2017
4
A Review of 7 Cases of Laparoscopic Cholecystectomy for Pediatric Cholecystolithiasis. ( 28904273 )
2017
5
Preoperative hypoalbuminemia is an independent risk factor for conversion from laparoscopic to open cholecystectomy in patients with cholecystolithiasis. ( 27283337 )
2016
6
Single-stage management with combined tri-endoscopic approach for concomitant cholecystolithiasis and choledocholithiasis. ( 27126621 )
2016
7
Intraoperative endoscopic nasobiliary drainage over primary closure of the common bile duct for choledocholithiasis combined with cholecystolithiasis: a cohort study of 211 cases. ( 27864721 )
2016
8
Endoscopic-Laparoscopic Cholecystolithotomy in Treatment of Cholecystolithiasis Compared With Traditional Laparoscopic Cholecystectomy. ( 27579981 )
2016
9
Endoscopic minimal invasive cholecystolithotomy vs laparoscopic cholecystectomy in treatment of cholecystolithiasis in China: a meta-analysis. ( 25527194 )
2015
10
Prospective multicentre cohort study of patient-reported outcomes after cholecystectomy for uncomplicated symptomatic cholecystolithiasis. ( 26201942 )
2015
11
Abdominal regional fat distribution on MRI correlates with cholecystolithiasis. ( 25310024 )
2014
12
Single-incision laparoscopic cholecystectomy for cholecystolithiasis coinciding with cavernous transformation of the portal vein: report of a case. ( 23578019 )
2013
13
Meta-analysis of laparoscopic versus open cholecystectomy for patients with liver cirrhosis and symptomatic cholecystolithiasis. ( 23034741 )
2013
14
The predictive value of pre-operative symptoms including upper gastrointestinal endoscopy before laparoscopic cholecystectomy for elective symptomatic cholecystolithiasis. ( 24899324 )
2013
15
A new strategy of minimally invasive surgery for cholecystolithiasis: calculi removal and gallbladder preservation. ( 24481280 )
2013
16
Symptomatic cholecystolithiasis after cholecystectomy. ( 23362056 )
2013
17
Dubin-Johnson syndrome with cholecystolithiasis and choledocholithiasis. ( 23708305 )
2013
18
Cholecystolithiasis after gastric bypass: a clinical, biochemical, and ultrasonographic 3-year follow-up study. ( 22767176 )
2012
19
Tiny cystine stones in the gallbladder of a patient with cholecystolithiasis complicating acute cholecystitis: a case report. ( 22472465 )
2012
20
Heterotopic pancreas in gall bladder associated with chronic cholecystolithiasis. ( 23776830 )
2012
21
Development of a real-time PCR assay for the detection of Clonorchis sinensis DNA in gallbladder bile and stone samples from patients with cholecystolithiasis. ( 22669695 )
2012
22
Cholecystolithiasis is associated with Clonorchis sinensis infection. ( 22905137 )
2012
23
Long-term outcome of endoscopic papillotomy for choledocholithiasis with cholecystolithiasis. ( 20447201 )
2010
24
Open, small-incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato-Biliary Group reviews. ( 20091665 )
2010
25
Systematic review: open, small-incision or laparoscopic cholecystectomy for symptomatic cholecystolithiasis. ( 19035965 )
2009
26
Randomized clinical trial of small-incision and laparoscopic cholecystectomy in patients with symptomatic cholecystolithiasis: primary and clinical outcomes. ( 18427025 )
2008
27
Prevalence of cholecystolithiasis and its management among kidney/pancreas-transplanted type 1 (insulin-dependent) diabetic patients. ( 18499558 )
2008
28
Effect of Lidan Granule on bile lithogenesis in patients with choledocholithiasis combined with cholecystolithiasis. ( 18679607 )
2008
29
Gastric emptying before and after cholecystectomy in patients with cholecystolithiasis. ( 18705281 )
2008
30
Anaesthesiological considerations in small-incision and laparoscopic cholecystectomy in symptomatic cholecystolithiasis: implications for pulmonary function. A randomized clinical trial. ( 17697302 )
2007
31
Behavior of the common bile duct diameter before and 12 years after choledochostomy for cholecystolithiasis and choledocholithiasis. A prospective study. ( 17682828 )
2007
32
Laparoscopic versus small-incision cholecystectomy for patients with symptomatic cholecystolithiasis. ( 17054284 )
2006
33
Laparoscopic versus open cholecystectomy for patients with symptomatic cholecystolithiasis. ( 17054285 )
2006
34
Small-incision versus open cholecystectomy for patients with symptomatic cholecystolithiasis. ( 17054215 )
2006
35
Relation of gallbladder function and Helicobacter pylori infection to gastric mucosa inflammation in patients with symptomatic cholecystolithiasis. ( 16641551 )
2006
36
Gallstone disease: Surgical aspects of symptomatic cholecystolithiasis and acute cholecystitis. ( 17127186 )
2006
37
Current status of laparoscopic therapy of cholecystolithiasis and common bile duct stones. ( 16352891 )
2005
38
Bouveret's syndrome: a rare complication of cholecystolithiasis. ( 16174186 )
2005
39
Transforming growth factor-beta pathway is activated in cholecystolithiasis. ( 15702358 )
2005
40
Somatosensory changes in the referred pain area in patients with cholecystolithiasis. ( 16003137 )
2005
41
Detection of nanobacteria in serum, bile and gallbladder mucosa of patients with cholecystolithiasis. ( 15780215 )
2005
42
Short- versus long-sequence MRI cholangiography for the preoperative imaging of the common bile duct in patients with cholecystolithiasis. ( 16021379 )
2005
43
Segmental adenomyomatosis of the gallbladder predisposes to cholecystolithiasis. ( 15549435 )
2004
44
Medical image. Magnetic resonance cholangiopancreatography (MRCP) demonstrating cholecystolithiasis and aberrant pancreatic duct anatomy. ( 15326512 )
2004
45
Symptomatic cholecystolithiasis after laparoscopic cholecystectomy. ( 15106630 )
2004
46
Predictions and associations of cholecystectomy in patients with cholecystolithiasis treated with extracorporeal shock wave lithotripsy. ( 15628729 )
2004
47
Is drip infusion cholecystocholangiography (DIC) an acceptable modality at cholecystectomy for cholecystolithiasis, considering the frequency of bile duct maljunction and intraoperative bile duct injury? ( 15127278 )
2004
48
Timing of laparoscopic cholecystectomy for acute cholecystitis with cholecystolithiasis. ( 15086155 )
2004
49
Bouveret's syndrome as a rare complication of cholecystolithiasis: report of a case. ( 12560912 )
2003
50
Relationship between cholecystolithiasis and polypoid gallbladder. ( 12958726 )
2003

Variations for Cholecystolithiasis

Expression for Cholecystolithiasis

Search GEO for disease gene expression data for Cholecystolithiasis.

Pathways for Cholecystolithiasis

Pathways related to Cholecystolithiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.56 BMP6 CTGF TGFB1
2 11.39 BMP6 CTGF TGFB1
3 11.13 BMP6 TGFB1
4 11.06 CTGF TGFB1
5 10.99 BMP6 CTGF TGFB1
6 10.86 CTGF TGFB1

GO Terms for Cholecystolithiasis

Cellular components related to Cholecystolithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.02 BMP6 CCK CRISP2 CTGF TGFB1

Biological processes related to Cholecystolithiasis according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.71 BMP6 CCK CTGF TGFB1
2 regulation of apoptotic process GO:0042981 9.7 BMP6 STK10 TGFB1
3 regulation of signaling receptor activity GO:0010469 9.62 BMP6 CCK CTGF TGFB1
4 positive regulation of epithelial cell proliferation GO:0050679 9.57 BMP6 TGFB1
5 SMAD protein signal transduction GO:0060395 9.56 BMP6 TGFB1
6 cell development GO:0048468 9.55 BMP6 TGFB1
7 regulation of MAPK cascade GO:0043408 9.54 BMP6 TGFB1
8 positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 9.51 BMP6 TGFB1
9 positive regulation of protein secretion GO:0050714 9.49 BMP6 TGFB1
10 positive regulation of bone mineralization GO:0030501 9.48 BMP6 TGFB1
11 cellular response to dexamethasone stimulus GO:0071549 9.46 ABCB4 TGFB1
12 positive regulation of collagen biosynthetic process GO:0032967 9.43 CTGF TGFB1
13 response to organic cyclic compound GO:0014070 9.43 ABCB4 CTGF TGFB1
14 response to vitamin D GO:0033280 9.37 ABCB4 TGFB1
15 receptor catabolic process GO:0032801 9.16 TGFB1 UVRAG
16 positive regulation of SMAD protein signal transduction GO:0060391 8.96 BMP6 TGFB1
17 response to estradiol GO:0032355 8.8 ABCB4 CTGF TGFB1

Molecular functions related to Cholecystolithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transforming growth factor beta receptor binding GO:0005160 9.16 BMP6 TGFB1
2 growth factor activity GO:0008083 9.13 BMP6 CTGF TGFB1
3 BMP receptor binding GO:0070700 8.62 BMP6 TGFB1

Sources for Cholecystolithiasis

3 CDC
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34 ICD10 via Orphanet
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45 MESH via Orphanet
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
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74 UMLS via Orphanet
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