Choledocholithiasis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: CHL039 MIFTS: 37	Choledocholithiasis Categories: Gastrointestinal diseases, Liver diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Choledocholithiasis

MalaCards integrated aliases for Choledocholithiasis:

Name: Choledocholithiasis ¹² ⁵⁶ ⁴⁵ ¹⁵ ¹⁷ ⁷⁴

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases Liver diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:11755

MeSH ⁴⁵ D042883

SNOMED-CT ⁶⁹ 49910001

EFO ¹⁷ EFO_1000865

UMLS ⁷⁴ C0701818

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Summaries for Choledocholithiasis

MalaCards based summary : Choledocholithiasis is related to cholelithiasis and cholecystolithiasis. An important gene associated with Choledocholithiasis is GPT (Glutamic--Pyruvic Transaminase), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. The drugs Midazolam and Meperidine have been mentioned in the context of this disorder. Affiliated tissues include liver, testes and lung.

Wikipedia : ⁷⁷ Common bile duct stone, also known as choledocholithiasis, is the presence of gallstones in the common... more...

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Related Diseases for Choledocholithiasis

Diseases related to Choledocholithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 110)

#	Related Disease	Score	Top Affiliating Genes
1	cholelithiasis	30.7	ABCB4 ALB GPT UGT1A1
2	cholecystolithiasis	30.5	ABCB4 STK10
3	cholangitis	30.5	ABCB4 ALB F2 GPT
4	cholecystitis	30.4	ABCB4 ALB F2 GPT
5	extrahepatic cholestasis	30.4	ABCB4 GPT
6	hepatitis	30.1	F2 GPT SLC17A5
7	sickle cell anemia	29.9	F2 UGT1A1
8	ascending cholangitis	29.9	ALB F2
9	biliary dyskinesia	29.8	SOBP STK10
10	liver cirrhosis	29.8	ALB F2 GPT SLC17A5
11	sclerosing cholangitis	29.8	ABCB4 ALB
12	cholangitis, primary sclerosing	29.7	ABCB4 ALB GPT
13	cholestasis	29.7	ABCB4 ALPP F2 GPT
14	portal hypertension	29.7	ALB F2 GPT
15	obstructive jaundice	29.6	ALB ALPP F2 GPT SLC17A5
16	infantile liver failure syndrome 1	29.4	ALB F2 GPT SLC17A5
17	pancreatitis	10.5
18	acute cholangitis	10.4
19	paraquat poisoning	10.3	GPT SLC17A5
20	pyridoxine deficiency	10.3	GPT SLC17A5
21	degos 'en cocarde' erythrokeratoderma	10.3
22	fatty liver disease, nonalcoholic 1	10.3	GPT SLC17A5
23	scrub typhus	10.3	GPT SLC17A5
24	hepatoportal sclerosis	10.3	F2 GPT
25	hepatitis d	10.2	F2 GPT
26	cholangiocarcinoma	10.2
27	legionnaires' disease	10.2	ALB SLC17A5
28	primary hepatic neuroendocrine carcinoma	10.1	ALPP GPT
29	protein-energy malnutrition	10.1	ALB GPT
30	antipyrine metabolism	10.1	ALB F2
31	non-a-e hepatitis	10.1	ALB F2
32	kernicterus	10.1	ALB UGT1A1
33	epstein-barr virus hepatitis	10.1	ALB F2
34	fournier gangrene	10.1	ALB F2
35	meningoencephalitis	10.1	ALB SLC17A5
36	abdominal tuberculosis	10.1	ALB F2
37	gallbladder disease	10.1	ABCB4 UGT1A1
38	splenic disease	10.1	ALB F2
39	esophageal varix	10.1	ALB F2
40	nonalcoholic steatohepatitis	10.1	F2 GPT SLC17A5
41	hypersplenism	10.1	ALB F2
42	hepatorenal syndrome	10.1	ALB F2
43	hepatic vascular disease	10.1	ALB F2
44	hellp syndrome	10.1	F2 GPT SLC17A5
45	pulmonary artery disease	10.1	ALB F2
46	acute pancreatitis	10.1
47	dysfibrinogenemia	10.1	ALB F2
48	vein disease	10.0	ALB F2
49	intermittent claudication	10.0	ALB F2
50	typhoid fever	10.0	ALB F2

Graphical network of the top 20 diseases related to Choledocholithiasis:

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Symptoms & Phenotypes for Choledocholithiasis

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Drugs & Therapeutics for Choledocholithiasis

Drugs for Choledocholithiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 49)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Midazolam

Approved, Illicit

Phase 4,Not Applicable

59467-70-8

4192

Meperidine

Approved

Phase 4,Not Applicable

57-42-1

4058

Etomidate

Approved

Phase 4

33125-97-2

36339 667484

Ursodeoxycholic acid

Approved, Investigational

Phase 4

128-13-2

31401

Anesthetics

Phase 4,Not Applicable

Central Nervous System Depressants

Phase 4

Peripheral Nervous System Agents

Phase 4

Analgesics, Opioid

Phase 4

Psychotropic Drugs

Phase 4

Neurotransmitter Agents

Phase 4

Anesthetics, Intravenous

Phase 4

Narcotics

Phase 4

Anti-Anxiety Agents

Phase 4

Adjuvants, Anesthesia

Phase 4

GABA Modulators

Phase 4

Analgesics

Phase 4

Anesthetics, General

Phase 4

GABA Agents

Phase 4

Hypnotics and Sedatives

Phase 4

Tranquilizing Agents

Phase 4

Gastrointestinal Agents

Phase 4

Cholagogues and Choleretics

Phase 4

Pharmaceutical Solutions

Phase 3

Glucagon

Approved

Not Applicable

16941-32-5

Chlorhexidine

Approved, Vet_approved

Not Applicable

55-56-1

2713 9552079

Scopolamine

Approved, Investigational

Not Applicable

6533-68-2, 51-34-3

5184

Indomethacin

Approved, Investigational

Not Applicable

53-86-1

3715

Pancrelipase

Approved, Investigational

Not Applicable

53608-75-6

Cefoxitin

Approved

Not Applicable

35607-66-0

441199

Cefotaxime

Approved

Not Applicable

63527-52-6

456256 5742673

Vitamin A

Approved, Nutraceutical, Vet_approved

Not Applicable

22737-96-8, 68-26-8, 11103-57-4

9904001 445354

Plasminogen Inactivators

Early Phase 1

Tissue Plasminogen Activator

Early Phase 1

Plasminogen

Early Phase 1

Plasminogen Activator Inhibitor 1

Early Phase 1

Glucagon-Like Peptide 1

Not Applicable

Anti-Infective Agents, Local

Not Applicable

Chlorhexidine gluconate

Not Applicable

Anti-Infective Agents

Not Applicable

Disinfectants

Not Applicable

Anti-Bacterial Agents

,Not Applicable

Antibiotics, Antitubercular

,Not Applicable

Butylscopolammonium Bromide

Not Applicable

pancreatin

Not Applicable

retinol

Not Applicable

Retinol palmitate

Not Applicable

Antitubercular Agents

Not Applicable

Cephalosporins

Not Applicable

Liver Extracts

Not Applicable

Interventional clinical trials:

(show top 50) (show all 53)

#	Name	Status	NCT ID	Phase	Drugs
1	Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla	Unknown status	NCT02703077	Phase 4
2	Etomidate vs. Midazolam for Sedation During ERCP	Completed	NCT02027311	Phase 4	Etomidate;Midazolam;Meperidine
3	UDCA for Symptomatic Gallstone Disease	Completed	NCT00161083	Phase 4	ursodeoxycholic acid
4	Effect of Saline Irrigation to DEcrease Rate Of Residual Common Bile Duct Stones	Unknown status	NCT01425177	Phase 3
5	Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones	Completed	NCT02592811	Phase 3
6	Magnetic Resonance Cholangiopancreatography Versus Endoscopic Retrograde Cholangiopancreatography in the Approach to Patients With Suspected Biliary Obstruction	Terminated	NCT01424657	Phase 3
7	Laparoendoscopic Rendez Vous Versus Standard Two Stage Approach for the Management of Cholelithiasis/Choledocholithiasis	Unknown status	NCT00416234	Not Applicable
8	The Clinical Characteristics of the Patients With Choledocholithiasis Without Cholangitis	Unknown status	NCT02647593
9	A Prospective Randomized Study Comparing Different Dilation Durations for Endoscopic Papillary Balloon Dilatation	Unknown status	NCT00451581	Not Applicable
10	Comparison of Papillary Balloon Dilatation Vs.Sphincterotomy for Lithotripsy in Difficult Sphincterotomy or Distal CBD Tapering	Unknown status	NCT00329888
11	Direct Peroral Cholangioscopy by Using an Ultra-slim Upper Endoscope	Unknown status	NCT02276157
12	Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography).	Unknown status	NCT01414400	Not Applicable
13	Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration	Unknown status	NCT02461147
14	Timing of Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiography for Acute Biliary Pancreatitis	Unknown status	NCT01687959	Early Phase 1
15	Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders	Unknown status	NCT01438385
16	Los Angeles Prospective GI Biliary and EUS Series	Unknown status	NCT02196935
17	Laser Versus Mechanical Lithotripsy of Bile Duct Stones	Completed	NCT01759979	Not Applicable
18	Prospective Evaluation of the Ability of Spyglass Cholangioscopy to Facilitate Radiation Free ERCP	Completed	NCT03074201	Not Applicable
19	Randomized Trial of ERCP Then Laparoscopic Cholecystectomy vs. Laparoscopic Cholecystectomy Plus Laparoscopic Common Bile Duct Exploration in Patients With Likely Choledocholithiasis	Completed	NCT00807729	Not Applicable
20	EUS Guided ERCP in Bile Duct Stone Removal	Completed	NCT02870686	Not Applicable
21	Left Lateral Position and Prone Position for Endoscopic Retrograde Cholangiopancreatography	Completed	NCT02594475	Not Applicable
22	Effect of 8.5 F Plastic Stent Without Proximal Flap on Prevention of Post-ERCP Cholangitis	Completed	NCT02594891	Not Applicable
23	Study of Endoscopic Sphincterotomy With Needle Knife Papillotome in Patients of Ampullary Impacted Stone	Completed	NCT00173368
24	Laryngeal Mask Airway Supreme Versus the Tracheal Tube as an Airway Device in Elective Laparoscopic Cholecystectomy	Completed	NCT02037958	Not Applicable
25	Comparison Between Pre and Intraoperative ERCP in Treatment of Common Bile Duct Stones	Completed	NCT01046552	Not Applicable
26	Prospective Study of the Risk of Bacteremia in Directed Cholangioscopic Examination of the CBD	Completed	NCT01673269	Not Applicable
27	Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures and Gall Stones	Completed	NCT01683240	Not Applicable
28	Prospective Evaluation of Residual Bile Duct Stone by Peroral Cholangioscopy After Conventional ERCP	Completed	NCT03482375
29	Loop-tipped Guidewire in Selective Biliary Cannulation	Completed	NCT02028845	Not Applicable
30	ERCP in Super-aged Patients Considering Difficult Cannulation: Challenges and Adverse Events	Completed	NCT03771547
31	Early EUS in Acute Biliary Pancreatitis	Completed	NCT02430285	Not Applicable
32	Routine Bile Collection for Microbiological Analysis During Cholangiography	Completed	NCT01003782
33	Cytological Evaluation of Biliary Epithelium After Endoscopic Sphincterotomy	Completed	NCT01135732
34	Acute Biliary Pancreatitis - Optimal Time for Cholecystectomy	Completed	NCT03085407	Not Applicable
35	Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy	Completed	NCT01824186	Not Applicable
36	Incidence and Risk Factor of Post-ERCP Pancreatitis in Chronic Pancreatitis	Completed	NCT02781987
37	Role of EUS in High Risk of Choledocholithiasis	Recruiting	NCT03250286	Not Applicable
38	Comparison of LCBDE vs ERCP + LC for Choledocholithiasis	Recruiting	NCT02515474	Not Applicable
39	"Endoscopy First" or "Laparoscopic Cholecystectomy First" for Patients With Intermediate Risk of Choledocholithiasis	Recruiting	NCT03658863	Not Applicable
40	The Comparisons of One-stage and Two-stage Stone Removal in Moderate Cholangitis	Recruiting	NCT03754491	Not Applicable
41	Cholangiography Using Carbon Dioxide Versus Iodinated Contrast in ERCP	Recruiting	NCT02611453	Not Applicable
42	Papillary Balloon Dilation Versus Laser Lithotripsy	Recruiting	NCT03536247	Not Applicable
43	Microbiomes in Patients of Recurrent Common Bile Duct Stones	Recruiting	NCT03102281
44	Long-duration EPBD vs EST for Removal of Biliary Stones	Recruiting	NCT03683485	Not Applicable
45	Effectiveness of Prophylactic Antibiotics to Prevent Post Endoscopic Retrograde Cholangio Pancreatography Bacteremia in Biliary Obstruction Patient	Recruiting	NCT02958059	Not Applicable
46	Non-Complex Biliary Stones DSC vs ERC	Recruiting	NCT03421340	Not Applicable
47	Chinese Registry Study on Treatment of Cholecysto-Choledocholithiasis	Active, not recruiting	NCT02554097
48	A Prospective Study of Treating Duodenal Papillary Sphincter in Different Ways During ERCP	Enrolling by invitation	NCT03416205	Not Applicable
49	Early MRI in Acute GallstonE Disease	Not yet recruiting	NCT03709030	Not Applicable
50	Study Investigating the Best Method of Treatment of Bile Duct Stones in Higher Risk Patients	Terminated	NCT00612846	Not Applicable

Search NIH Clinical Center for Choledocholithiasis

Cochrane evidence based reviews: choledocholithiasis

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Genetic Tests for Choledocholithiasis

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Anatomical Context for Choledocholithiasis

MalaCards organs/tissues related to Choledocholithiasis:

⁴²

Liver, Testes, Lung, Colon, Heart, Thyroid

Sources

Publications for Choledocholithiasis

Articles related to Choledocholithiasis:

(show top 50) (show all 959)

#	Title	Authors	Year
1	COMPARATIVE EVALUATION OF MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY AND PERIOPERATIVE CHOLANGIOGRAPHY IN PATIENTS WITH SUSPECT CHOLEDOCHOLITHIASIS. ( 30624525 )	Perales SR...Crema E	2019
2	Single-Stage Endoscopic Stone Extraction and Cholecystectomy during the Same Hospitalization: What is the Optimal Strategy for Patients with Choledocholithiasis and Cholelithiasis? ( 30625266 )	Lee TY	2019
3	External Validation of Different Scoring Systems for Suspected Choledocholithiasis. ( 30636244 )	Tamini N...Gianotti L	2019
4	Laparoscopic cholecystectomy after endoscopic treatment of choledocholithiasis: a retrospective comparative study. ( 30644060 )	Trejo-?vila M...Valenzuela-Salazar C	2019
5	Combination of serum gamma-glutamyltransferase and alkaline phosphatase in predicting the diagnosis of asymptomatic choledocholithiasis secondary to cholecystolithiasis. ( 30705891 )	Mei Y...Jia JH	2019
6	Use of intraoperative cholangiography in patients diagnosed with choledocholithiasis with preoperative imaging or endoscopic study. ( 30768067 )	D?az-Osuna JJ...Ch?vez-P?rez CE	2019
7	Role of Cholecystectomy in Choledocholithiasis Patients Underwent Endoscopic Retrograde Cholangiopancreatography. ( 30778100 )	Wang CC...Lin CC	2019
8	Sphincterotomy plus balloon dilation versus sphincterotomy alone for choledocholithiasis: a meta-analysis. ( 30786316 )	Dong SQ...Wang HL	2019
9	Choledocholithiasis treated with a pediatric duodenoscope in a neonate. ( 30803055 )	Kida A...Sakai A	2019
10	Epidemiology and disease characteristics of symptomatic choledocholithiasis in Sri Lanka. ( 30863806 )	De Silva WSL...De Silva MM	2019
11	Pancreaticopleural fistula associated with choledocholithiasis: An infrequent complication of acute pancreatitis. ( 29530342 )	CarriA^n-MartA-n L....BaA+ares R.	2018
12	Laparoscopic common bile duct exploration versus endoscopic retrograde cholangiopancreatography for choledocholithiasis found at time of laparoscopic cholecystectomy. ( 29477230 )	Al-Musawi J....Martinez-Isla A.	2018
13	Performance of the Choledocholithiasis Diagnostic Score in Patients with Acute Cholecystitis. ( 29457047 )	Gouveia C....Cravo M.	2018
14	Gallstone Pancreatitis and Choledocholithiasis: Using Imaging and Laboratory Trends to Predict the Likelihood of Persistent Stones at Cholangiography. ( 29626246 )	Panda N....Dante Yeh D.	2018
15	Laparoscopic Common Bile Duct Exploration for Choledocholithiasis: Analysis of Practice Patterns of Intermountain HealthCare. ( 29518526 )	Gilsdorf D....Price R.	2018
16	Physicians infrequently miss choledocholithiasis prior to cholecystectomy in the United States. ( 29208548 )	Kruger A.J....Krishna S.G.	2018
17	Successful endoscopic sphincterotomy for choledocholithiasis in a patient with severe hemophilia A and inhibitors. ( 29396835 )	Sugiura R....Sakamoto N.	2018
18	Outcomes Associated With Timing of ERCP in Acute Cholangitis Secondary to Choledocholithiasis. ( 29356786 )	Parikh M.P....Sanaka M.R.	2018
19	The Safety and Efficacy of Laparoscopic Common Bile Duct Exploration Combined with Cholecystectomy for the Management of Cholecysto-choledocholithiasis: An Up-to-date Meta-analysis. ( 29533266 )	Pan L....Cai X.	2018
20	Risk assessment of choledocholithiasis prior to laparoscopic cholecystectomy and its management options. ( 29774157 )	Aleknaite A....Strupas K.	2018
21	Impact of Jaundice on Outcomes Following Emergency Laparoscopic Cholecystectomy in Patients with Choledocholithiasis. ( 29541824 )	Poh B.R....Croagh D.G.	2018
22	Cholelithiasis and choledocholithiasis in children; risk factors for development. ( 29763444 )	Frybova B....Keil R.	2018
23	Electrohydraulic lithotripsy under double-balloon endoscope-assistedA direct cholangioscopy for treatmentA ofA choledocholithiasis in a patient with Roux-en-YA gastrectomy. ( 29916492 )	Sato T....Koike K.	2018
24	Hemodialysis is a strong risk factor for post-endoscopic sphincterotomy bleeding in patients with choledocholithiasis. ( 29756014 )	Nakaji S....Harasawa H.	2018
25	Role of Cholecystectomy After Endoscopic Sphincterotomy in the Management of Choledocholithiasis in High-risk Patients: A Systematic Review and Meta-Analysis. ( 29912758 )	Khan M.A....Wilcox C.M.	2018
26	Nonsurgical management of an extensive spontaneous spinal epidural hematoma causing quadriplegia and respiratory distress in a choledocholithiasis patient: A case report: Erratum. ( 29369212 )		2018
27	Predictors for choledocholithiasis in patients undergoing endoscopic ultrasound. ( 29979088 )	Quispel R....Bruno M.J.	2018
28	Pearl-White Gallstones Causing Choledocholithiasis. ( 29392151 )	Stoner P....Draganov P.	2018
29	Single-stage laparoscopic management of choledocholithiasis: An analysis after implementation of a mastery learning resident curriculum. ( 29191675 )	Schwab B....Hungness E.S.	2018
30	Various approaches of laparoscopic common bile duct exploration plus primary duct closure for choledocholithiasis: A systematic review and meta-analysis. ( 29627156 )	He M.Y....Ren W.W.	2018
31	Micro-Incision of the Cystic Duct Confluence in Laparoscopic Common Bile Duct Exploration for Elderly Patients with Choledocholithiasis. ( 29973752 )	Niu X....Wei J.	2018
32	Management of endoscopic biliary stenting for choledocholithiasis: Evaluation of stent-exchange intervals. ( 29375741 )	Tohda G....Dochin M.	2018
33	Safety and Efficacy of Endoscopic Retrograde Cholangiopancreatography for Choledocholithiasis in Long-Term Dialysis: A Propensity Score Analysis. ( 29767390 )	Kim S.B....Kim T.N.	2018
34	Human fibrin sealant reduces post-operative bile leakage of primary closure after laparoscopic common bile duct exploration in patients with choledocholithiasis. ( 29974875 )	Zhang X....Sun Y.	2018
35	The added value of tomosynthesis in endoscopic retrograde cholangiography with radiography for the detection of choledocholithiasis. ( 29630390 )	Suyama Y....Ogawa K.	2018
36	Catheter probe extraductal ultrasound (EDUS) exploration of the common bile duct is safe in elderly patients with suspicion of choledocholithiasis after distal gastrectomy. ( 29600432 )	Togliani T....Fusaroli P.	2018
37	Efficacy and Safety of Single-Session Endoscopic Stone Removal for Acute Cholangitis Associated with Choledocholithiasis. ( 30175087 )	Sato J...Itoh F	2018
38	Diagnostic value of elevated serum carbohydrate antigen 199 level in acute cholangitis secondary to choledocholithiasis. ( 30294608 )	Mei Y...Jia JH	2018
39	Preoperative predictors of choledocholithiasis in patients presenting with acute calculous cholecystitis. ( 30465770 )	Chisholm PR...Prabhu A	2018
40	Two Cases of Acute Cholecystitis and Symptomatic Choledocholithiasis in Two Women Less than 40-Years-of-Age with Hormonal Intrauterine Devices. ( 30584481 )	Shields HM...Sidhu H	2018
41	Inpatient Choledocholithiasis Requiring ERCP and Cholecystectomy: Outcomes of a Combined Single Inpatient Procedure Versus Separate-Session Procedures. ( 28971298 )	Passi M...Trindade AJ	2018
42	Comparative Study of Three Bile Duct Closure Methods Following Laparoscopic Common Bile Duct Exploration for Choledocholithiasis. ( 28976804 )	Parra-Membrives P...Jim?nez-Riera G	2018
43	Choledocholithiasis in Roux-en-Y gastric bypass patients. ( 29453381 )	Alkhatib AA...Alasadi M	2018
44	Once upon a Time a Guideline Was Used for the Evaluation of Suspected Choledocholithiasis: A Fairy Tale or a Nightmare? ( 29457044 )	Canena J	2018
45	Association Between Juxtapapillary Duodenal Diverticula and Risk of Choledocholithiasis: a Systematic Review and Meta-analysis. ( 30022443 )	Wijarnpreecha K...Ungprasert P	2018
46	In-Hospital Pediatric ERCP is Associated with Shorter Hospitalization for Children with Choledocholithiasis. ( 30044307 )	Bonasso PC...Dassinger MS	2018
47	Single-stage management of cholelithiasis and choledocholithiasis: Laparoscopic cholecystectomy and intra-operative endoscopic sphincterotomy (with video). ( 30072276 )	Dumange Chapuis-Roux E...Regimbeau JM	2018
48	Self-expandable metal stents for choledocholithiasis in Billroth II gastrectomy patients. ( 30126827 )	Han MG...Park SY	2018
49	The reasonable drainage option after laparoscopic common bile duct exploration for the treatment of choledocholithiasis. ( 30145281 )	Xiao LK...Xie W	2018
50	Percutaneous Transcholecystic Management of Choledocholithiasis: A Next Horizon for Interventional Radiologists? ( 30226458 )	vanSonnenberg E...Panchanathan R	2018

Sources

Genes for Choledocholithiasis

Genes related to Choledocholithiasis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	GPT	Glutamic--Pyruvic Transaminase	Protein Coding	28.29	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	15765973 15286869 15667485
2	SLC17A5	Solute Carrier Family 17 Member 5	Protein Coding	24.18	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	15667485 8677945
3	GUSB	Glucuronidase Beta	Protein Coding	21.81	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	9383634
4	ABCB4	ATP Binding Cassette Subfamily B Member 4	Protein Coding	21.23	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	UGT1A1	UDP Glucuronosyltransferase Family 1 Member A1	Protein Coding	20.27	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	F2	Coagulation Factor II, Thrombin	Protein Coding	20.22	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	ALB	Albumin	Protein Coding	20.21	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	ALPP	Alkaline Phosphatase, Placental	Protein Coding	19.85	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	STK10	Serine/Threonine Kinase 10	Protein Coding	15.65	DISEASES inferred ¹⁵
10	SOBP	Sine Oculis Binding Protein Homolog	Protein Coding	14.96	DISEASES inferred ¹⁵

Sources

Variations for Choledocholithiasis

Sources

Expression for Choledocholithiasis

Search GEO for disease gene expression data for Choledocholithiasis.

Sources

Pathways for Choledocholithiasis

Pathways related to Choledocholithiasis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	FOXA2 and FOXA3 transcription factor networks ¹	10.27	ALB F2

Sources

GO Terms for Choledocholithiasis

Cellular components related to Choledocholithiasis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular exosome	GO:0070062	9.1	ABCB4 ALB F2 GPT GUSB STK10

Biological processes related to Choledocholithiasis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	acute-phase response	GO:0006953	8.62	F2 UGT1A1

Molecular functions related to Choledocholithiasis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	pyridoxal phosphate binding	GO:0030170	8.62	ALB GPT

Sources

Sources for Choledocholithiasis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia