MCID: CHL039
MIFTS: 39

Choledocholithiasis

Categories: Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Choledocholithiasis

MalaCards integrated aliases for Choledocholithiasis:

Name: Choledocholithiasis 12 54 43 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11755
MeSH 43 D042883
SNOMED-CT 67 49910001
UMLS 71 C0701818

Summaries for Choledocholithiasis

MalaCards based summary : Choledocholithiasis is related to cholecystitis and peritonitis. An important gene associated with Choledocholithiasis is GPT (Glutamic--Pyruvic Transaminase), and among its related pathways/superpathways is Folate Metabolism. The drugs Midazolam and Meperidine have been mentioned in the context of this disorder. Affiliated tissues include liver, testes and heart.

Wikipedia : 74 Common bile duct stone, also known as choledocholithiasis, is the presence of gallstones in the common... more...

Related Diseases for Choledocholithiasis

Diseases related to Choledocholithiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 337)
# Related Disease Score Top Affiliating Genes
1 cholecystitis 31.2 GPT F2 CCK ALB
2 peritonitis 31.0 F2 CRP ALB
3 acute pancreatitis 30.6 GPT CRP CCK ALB
4 hepatic coma 30.6 GPT F2 ALB
5 liver cirrhosis 30.4 SLC17A5 GPT GGT1 F2 ALB
6 extrahepatic cholestasis 30.4 GPT GGT1 ALPP ABCB4
7 sickle cell anemia 30.4 UGT1A1 F2 ALB
8 hepatic encephalopathy 30.4 SLC17A5 GPT F2 ALB
9 pancreatitis 30.3 SLC17A5 GGT1 CRP CCK
10 drug-induced hepatitis 30.3 UGT1A1 GPT ALB
11 obstructive jaundice 30.3 SLC17A5 GPT GGT1 F2 CRP ALPP
12 acute kidney failure 30.3 GPT F2 ALB
13 cholelithiasis 30.2 UGT1A1 GPT GGT1 CRP CCK ALB
14 portal hypertension 30.2 GPT F2 ALB
15 suppurative cholangitis 30.1 GPT GGTLC3 GGT2 CRP ABCB4
16 thrombophlebitis 30.1 F2 CRP ALB
17 biliary dyskinesia 30.0 GPT CCK
18 cholecystolithiasis 30.0 GPT GGTLC3 CRP CEACAM5 CCK
19 klatskin's tumor 30.0 GPT CEACAM5 ALB
20 bronchopneumonia 29.9 GUSB GPT CRP ALB
21 acute cystitis 29.9 GPT F2 CRP ALB
22 pulmonary embolism 29.9 F2 CRP ALB
23 autoimmune hepatitis 29.8 SLC17A5 GPT GGT1 F2 ALB
24 hyperthyroidism 29.8 GPT CRP ALPP ALB
25 ascending cholangitis 29.8 GPT GGTLC3 GGT2 F2 CRP ALB
26 respiratory failure 29.7 GPT F2 CRP ALB
27 ileus 29.7 F2 CRP CCK
28 fatty liver disease 29.6 SLC17A5 GPT GGT1 CRP ALB
29 intestinal obstruction 29.6 GPT CRP CEACAM5 ALB
30 cholestasis 29.6 SLC17A5 GPT GGT1 F2 CCK ALPP
31 bile duct cysts 29.5 GPT GGTLC3 GGT2 GGT1 CEACAM5 ABCB4
32 acute cholangitis 29.5 GPT GGTLC3 GGT2 GGT1 F2 CRP
33 leptin deficiency or dysfunction 29.4 GPT CRP CCK ALB
34 cholangitis 29.3 SLC17A5 MIR222 GPT GGT1 F2 CRP
35 alcohol use disorder 29.3 SLC17A5 GPT GGTLC3 GGT2 GGT1 ALB
36 deficiency anemia 29.3 GGTLC3 GGT2 GGT1 CRP ALB
37 primary biliary cirrhosis 29.3 SLC17A5 GPT GGT1 F2 ALPP ALB
38 alcohol dependence 29.0 SLC17A5 GPT GGT1 CCK
39 sclerosing cholangitis 29.0 MIR222 GPT GGT1 F2 CEACAM5 ALB
40 liver disease 29.0 UGT1A1 SLC17A5 GPT GGT1 F2 ALPP
41 bilirubin metabolic disorder 28.8 UGT1A1 SLC17A5 GPT GGTLC3 GGT2 GGT1
42 cholangitis, primary sclerosing 28.5 MIR222 GPT GGTLC3 GGT2 GGT1 F2
43 biliary tract disease 27.5 MIR222 GPT GGTLC3 GGT2 GGT1 F2
44 gallbladder disease 27.1 UGT1A1 MIR222 GPT GGTLC3 GGT2 GGT1
45 bile duct disease 26.9 MIR222 GPT GGTLC3 GGT2 GGT1 F2
46 gallbladder disease 1 10.8
47 paraquat poisoning 10.6 SLC17A5 GPT
48 hepatoportal sclerosis 10.6 GPT F2
49 dipetalonemiasis 10.6 GPT ALB
50 non-a-e hepatitis 10.5 F2 ALB

Graphical network of the top 20 diseases related to Choledocholithiasis:



Diseases related to Choledocholithiasis

Symptoms & Phenotypes for Choledocholithiasis

Drugs & Therapeutics for Choledocholithiasis

Drugs for Choledocholithiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 57)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
2
Meperidine Approved Phase 4 57-42-1 4058
3
Etomidate Approved Phase 4 33125-97-2 36339 667484
4
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
5
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
6
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
7
Ofloxacin Approved Phase 4 82419-36-1 4583
8 Anti-Anxiety Agents Phase 4
9 Tranquilizing Agents Phase 4
10 Neurotransmitter Agents Phase 4
11 Narcotics Phase 4
12 Adjuvants, Anesthesia Phase 4
13 GABA Agents Phase 4
14 Analgesics, Opioid Phase 4
15 Anesthetics, General Phase 4
16 GABA Modulators Phase 4
17 Psychotropic Drugs Phase 4
18 Hypnotics and Sedatives Phase 4
19 Anesthetics, Intravenous Phase 4
20 Central Nervous System Depressants Phase 4
21 Analgesics Phase 4
22 Gastrointestinal Agents Phase 4
23 Cholagogues and Choleretics Phase 4
24 Antibiotics, Antitubercular Phase 4
25 Antitubercular Agents Phase 4
26 Anti-Bacterial Agents Phase 4
27 Anti-Infective Agents Phase 4
28 Renal Agents Phase 4
29 Cytochrome P-450 Enzyme Inhibitors Phase 4
30 Topoisomerase Inhibitors Phase 4
31 Anti-Infective Agents, Urinary Phase 4
32 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
33 Pharmaceutical Solutions Phase 3
34
Glucagon Approved 16941-32-5
35
Indomethacin Approved, Investigational 53-86-1 3715
36
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
37
Cefotaxime Approved 63527-52-6 456256 5742673
38
Cefoxitin Approved 35607-66-0 441199
39
Scopolamine Approved, Investigational 51-34-3, 6533-68-2 5184
40
Pancrelipase Approved, Investigational 53608-75-6
41
Vitamin A Approved, Nutraceutical, Vet_approved 68-26-8, 11103-57-4, 22737-96-8 445354 9904001
42 Plasminogen Activator Inhibitor 1 Early Phase 1
43 Plasminogen Inactivators Early Phase 1
44 Plasminogen Early Phase 1
45 Tissue Plasminogen Activator Early Phase 1
46 Chlorhexidine gluconate
47 Disinfectants
48 Anti-Infective Agents, Local
49 Glucagon-Like Peptide 1
50 Anesthetics

Interventional clinical trials:

(show top 50) (show all 66)
# Name Status NCT ID Phase Drugs
1 Endoscopic Treatment of Difficult Bile Duct Stones: Use of Direct Visualization System ("Spyglass Direct Visualization System") Associated With Electrohydraulic Lithotripsy (EHL) X Hydrostatic Balloon Dilation of the Major Duodenal Papilla Unknown status NCT02703077 Phase 4
2 Etomidate With Meperidine vs Midazolam With Meperidine for Sedation During Endodscopic Retrograde Cholangiopancreatogram (ERCP) Completed NCT02027311 Phase 4 Etomidate;Midazolam;Meperidine
3 Studie Naar De Effectiviteit Van Ursodeoxycholzuur Ter Preventie Van Galsteen-Gerelateerde Klachten Bij patiënten in Afwachting Van Een Cholecystectomie Completed NCT00161083 Phase 4 ursodeoxycholic acid
4 Randomized Trial of Short Antibiotic Course to Decrease Post ERCP Cholangitis Recruiting NCT03087656 Phase 4 Ceftriaxone;Levofloxacin
5 Effect of Saline Irrigation to Decrease Rate of Residual Common Bile Duct Stones Unknown status NCT01425177 Phase 3
6 Endoscopic Sphincterotomy Plus Large-Balloon Dilatation (ESLBD) Versus Conventional Endoscopic Treatment for Removal of Large Common Bile Duct Stones : A Prospective Comparative Multi Center Randomized Study Completed NCT02592811 Phase 3
7 Magnetic Resonance Cholangiopancreatography Versus Endoscopic Retrograde Cholangiopancreatography in the Approach to Patients With Suspected Biliary Obstruction Terminated NCT01424657 Phase 3
8 The Clinical Characteristics of the Patients With Choledocholithiasis Without Cholangitis Showing the High Level of Aminotransferase and the Establishment of New Nomenclature ; Gallstone Hepatitis Unknown status NCT02647593
9 Laparoendoscopic Rendez Vous (Intraoperative ERCP) vs Two Stage Approach (Preoperative ERCP Followed by Laparoscopic Cholecystectomy) for the Management of Cholelithiasis/Choledocholithiasis Unknown status NCT00416234
10 Comparison of Endoscopic Papillary Balloon Dilatation and Sphincterotomy for CBD Stones With Difficult Sphincterotomy or Distal CBD Tapering Unknown status NCT00329888
11 A Prospective Randomized Multicenter Study Comparing Different Dilation Durations During Endoscopic Papillary Balloon Dilatation for Bile Duct Stones. Unknown status NCT00451581
12 Initial Cholecystectomy With Intraoperative Cholangiography for Patients at Intermediate Risk of Common Bile Duct Stone Migration : Prospective Validation and Analysis Unknown status NCT02461147
13 Clinical Study of Abdominal Drainage in Laparoscopic Common Bile Duct Exploration With Primary Closure Unknown status NCT03120754
14 Prospective Study of Bacteremia and Infection Rates Following Cholangioscopy With the Spyglass Cholangioscope Unknown status NCT01414400
15 Direct Peroral Cholangioscopy by Using an Ultra-slim Upper Endoscope Unknown status NCT02276157
16 Prospective Randomized Clinical Study for Timing of Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiography for Acute Biliary Pancreatitis Unknown status NCT01687959 Early Phase 1
17 Endoscopic Retrograde Cholangiopancreatography, Endoscopic Ultrasound and Interventional Endoscopy in Pancreatico-biliary, Gastrointestinal and Esophageal Disorders Unknown status NCT01438385
18 Prospective Evaluation of the Ability of Spyglass Cholangioscopy to Facilitate Radiation Free ERCP Completed NCT03074201
19 Study of Endoscopic Sphincterotomy With Needle Knife Papillotome in Patients of Ampullary Impacted Stone Completed NCT00173368
20 A Randomized Controlled Trial Comparing Post-operative Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy Completed NCT01824186
21 Prospective Study of the Risk of Bacteremia in Directed Cholangioscopic Examination of the CBD Completed NCT01673269
22 Preoperative Versus Intraoperative Endoscopic Sphincterotomy for Management of Choledocholithiasis and Cholecystolithiasis Completed NCT01046552
23 Effect of 8.5 F Plastic Stent Without Proximal Flap on Prevention of Post-ERCP Cholangitis on Patients With choledocholithiasis--a Prospective Randomized Trial Completed NCT02594891
24 Loop-tipped Guidewire in Selective Biliary Cannulation: a Prospective, Randomized, Controlled Trial Completed NCT02028845
25 Inmediate Feeding Tolerance in Patients With Mild and Acute Biliary Pancreatitis vs Early Feeding Completed NCT03354065
26 The Laryngeal Mask Airway Supreme (TM) is an Effective Alternative to Laryngoscope-guided Tracheal Intubation for Patients Undergoing Elective Laparoscopic Cholecystectomy-- A Prospective Randomized Controlled Trial Completed NCT02037958
27 Routine Bile Collection for Microbiological Analysis During Cholangiography and Its Impact on Management of Cholangitis: Results of a Prospective Study Completed NCT01003782
28 Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures and Gall Stones Completed NCT01683240
29 Role of Complete Blood Picture in Predicting the Etiology of Extrahepatic Cholestasis Completed NCT03237247
30 Laparoscopy-Assisted Transgastric Endoscopic Retrograde Cholangiopancreatography for Choledocholithiasis After Roux-en-Y Gastric Bypass Completed NCT03925766
31 Success of Routine Intraoperative Cholangiography Completed NCT04052633
32 Prospective Evaluation of Residual Bile Duct Stone Detection by Peroral Cholangioscopy That Is Missed With Conventional ERCP and Cholangiogram Completed NCT03482375
33 A Prospective Randomized Trial Comparing EUS Guided ERCP Without Fluoroscopy With Standard ERCP in Common Bile Duct Stone Removal Completed NCT02870686
34 A Prospective, Randomized Study Comparing Efficacy and Safety Between Left Lateral Position and Prone Position for Endoscopic Retrograde Cholangiopancreatography Completed NCT02594475
35 ERCP in Super-aged Patients Considering Difficult Cannulation: Challenges and Adverse Events Completed NCT03771547
36 Early Endoscopic Ultrasound (EUS) in Acute Biliary Pancreatitis: a Prospective Pilot Study Completed NCT02430285
37 Prospective Randomized Trial of Laparoscopic Cholecystectomy Plus Laparoscopic Common Bile Duct Exploration (LC + LCBDE) Versus Endoscopic Retrograde Cholangiopancreatography Sphincterotomy Plus Laparoscopic Cholecystectomy (ERCP/S + LC) for Common Bile Duct Stone Disease Completed NCT00807729
38 Common Bile Duct Stone Management: What Have we Learned? Completed NCT02155244
39 Randomized Trial of Combination of Cholangioscopic Guided Laser Lithotripsy and Conventional Mechanical Versus Conventional Mechanical Methods for the Endoscopic Removal of Large Bile Duct Stones Completed NCT01759979
40 Cytological Evaluation of Biliary Epithelium After Previous Endoscopic Sphincterotomy for Benign Disease Completed NCT01135732
41 Role of EUS in High Risk of Choledocholithiasis Recruiting NCT03250286
42 Division of Hepato-gastroenterology; Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung,Taiwan Recruiting NCT03754491
43 Endosonography Versus Magnetic Resonance Cholangiopancreatography for Choledocholithiasis for Intermediate Risk of Choledocholithiasis (as Per European Society of Gastrointestinal Endoscopy Guidelines )- Randomized Controlled Trial Recruiting NCT04173624
44 Comparison of Two Management Strategies, "Endoscopy First" and "Laparoscopic Cholecystectomy First", for Patients With Gallbladder Stones and Intermediate Risk for Choledocholithiasis Recruiting NCT03658863
45 Effect of Intermittent Saline Irrigation in Reducing Choledocholithiasis Recurrence After ERCP Recruiting NCT03937037
46 CO2 Cholangiography as an Alternative to Iodinated Contrast in Endoscopic Retrograde Cholangiopancreatography Recruiting NCT02611453
47 Effectiveness of Prophylactic Antibiotics to Prevent Post Endoscopic Retrograde Cholangio Pancreatography Bacteremia in Biliary Obstruction Patient Recruiting NCT02958059
48 Prospective Randomized Trial of Cholangioscopy Guided Intraductal Lithotripsy Versus Papillary Balloon Dilation for the Endoscopic Treatment of Large Bile Duct Stones Recruiting NCT03536247
49 Prospective, Multi-center, Randomized Controlled Study Comparing Endoscopic Clearance of Non-Complex Biliary Stones Using Fluoroscopy/Radiation-Free Direct Solitary Cholangioscopy (DSC) to Standard of Care Endoscopic Retrograde Cholangiography (ERC) Recruiting NCT03421340
50 A Long Term Complications Comparison of Laparoscopic Common Bile Duct Exploration and Cholecystectomy Versus Sequential ERCP Followed by Laparoscopic Cholecystectomy for Choledocholithiasis: a Multicenter Randomized Controlled Study Recruiting NCT02515474

Search NIH Clinical Center for Choledocholithiasis

Cochrane evidence based reviews: choledocholithiasis

Genetic Tests for Choledocholithiasis

Anatomical Context for Choledocholithiasis

MalaCards organs/tissues related to Choledocholithiasis:

40
Liver, Testes, Heart, Pancreas, Kidney, Bone, Colon

Publications for Choledocholithiasis

Articles related to Choledocholithiasis:

(show top 50) (show all 3783)
# Title Authors PMID Year
1
Role of liver function tests in predicting common bile duct stones in acute calculous cholecystitis. 54 61
16078299 2005
2
Marked elevation in serum transaminases: an atypical presentation of choledocholithiasis. 54 61
15667485 2005
3
[Usefulness of endoscopic cholangiography and sphincterotomy in patients with biliary lithiasis]. 54 61
15765973 2004
4
[Predictors of choledocholithiasis in patients sustaining gallstones]. 54 61
15286869 2004
5
Lipopolysaccharides and beta-glucuronidase activity in choledochal bile in relation to choledocholithiasis. 54 61
9383634 1997
6
Increased intercellular adhesion molecule-1 serum concentration in cholestasis. 54 61
9007716 1996
7
Predicting the presence of choledocholithiasis in patients with symptomatic cholelithiasis. 54 61
8677945 1996
8
Jaundice. 54 61
1543099 1992
9
A Simple Risk Score to Predict Clavien-Dindo Grade IV and V Complications After Non-elective Cholecystectomy. 61
32030602 2020
10
Evaluation of serum MUC5AC in combination with CA19-9 for the diagnosis of pancreatic cancer. 61
32028958 2020
11
Precut fistulotomy for choledocholithiasis: what about long-term efficacy? 61
32016158 2020
12
Novel retrieval basket for the extraction of choledocholithiasis. 61
31434156 2020
13
Laparoscopic common bile duct exploration for elderly patients with choledocholithiasis: a systematic review and meta-analysis. 61
32016517 2020
14
Laparoscopic cholecystectomy in acute mild gallstone pancreatitis: how early is safe? 61
32009229 2020
15
Management of Choledocholithiasis in a 5-Month-Old Male Postprimary Repair of Esophageal Atresia with Tracheoesophageal Fistula. 61
31896899 2020
16
Partial protection with a chimeric tetraspanin-leucine aminopeptidase subunit vaccine against Opisthorchis viverrini infection in hamsters. 61
31991114 2020
17
Tailored access to the hepatobiliary system in post-bariatric patients: a tertiary care bariatric center experience. 61
31993808 2020
18
[A case of hemobilia due to the rupture of pancreaticoduodenal artery aneurysm with choledocholithiasis]. 61
31941863 2020
19
Endoscopic treatment for choledocholithiasis in asymptomatic patients. 61
31334888 2020
20
Primary closure after laparoscopic common bile duct exploration is feasible for elderly patients: 5-Year experience at a single institution. 61
31047771 2020
21
Percutaneous transhepatic laser lithotripsy for intrahepatic cholelithiasis: A technical report. 61
31545020 2019
22
Single-stage approach for the management of choledocolithiasis with concomitant cholelithiasis. Implementation of a protocol in a secondary hospital. 61
30704859 2019
23
Safety of Endoscopy and Its Outcome in Pregnancy. 61
31938593 2019
24
A novel pathogenic variant of ATP-binding cassette subfamily B member 4 causing gallstones in a young adult. 61
31115781 2019
25
Attendance to a "normal delivery" of choledocholithiasis. 61
31854316 2019
26
Clinical Efficacy Analysis of the Combination of the Laparoscope and Preoperative or Intraoperative Duodenoscope in the Treatment of Cholecystolithiasis with Choledocholithiasis: A Retrospective Study. 61
31647359 2019
27
Liver fluke-induced choledocholithiasis with biliary ductal obstruction. 61
31641397 2019
28
The rendezvous technique: An increasingly more acceptable option for choledocholithiasis treatment. 61
31421803 2019
29
Laparoscopic cholecystectomy after endoscopic treatment of choledocholithiasis: a retrospective comparative study. 61
30644060 2019
30
Laparoscopic common bile duct exploration with primary closure is safe for management of choledocholithiasis in elderly patients. 61
31474445 2019
31
Comparison on the Efficacy of Three Duct Closure Methods after Laparoscopic Common Bile Duct Exploration for Choledocholithiasis. 61
31857570 2019
32
Needle-knife fistulotomy vs. standard biliary sphincterotomy for choledocholithiasis: common bile duct stone recurrence and complication rate. 61
31828210 2019
33
Multidisciplinary Approach to Treating Severe Acute Pancreatitis in a Low-Volume Hospital. 61
31440777 2019
34
Drain in laparoscopic cholecystectomy in acute calculous cholecystitis: a randomised controlled study. 61
31871250 2019
35
Cholangiolithiasis postliver transplantation: Successful treatment utilizing percutaneous transhepatic cholangioscopy and laser lithotripsy. 61
31641393 2019
36
Acute cholangitis: Diagnosis and management. 61
31248783 2019
37
Outcomes of laparoscopic-assisted ERCP in gastric bypass patients at a community hospital center. 61
31823046 2019
38
A pictorial review of gall stones and its associated complications. 61
31931279 2019
39
Combined gastroscopic and choledochoscopic transabdominal nasobiliary drainage. 61
31595731 2019
40
Protocol for the CREST Choles (Chinese REgistry Study on Treatment of Cholecysto-Choledocholithiasis) study: an ambispective, multicenter, observational, open-cohort study. 61
31767583 2019
41
Predicting common bile duct stones by non-invasive parameters. 61
31810810 2019
42
More Is Less: The Advantages of Performing Concurrent Laparoscopic Cholecystectomy and Endoscopic Retrograde Cholangiopancreatography for Pediatric Choledocholithiasis. 61
31566486 2019
43
Postoperative rendezvous endoscopic retrograde cholangiopancreaticography as an option in the management of choledocholithiasis. 61
31768727 2019
44
A rescue approach using a neo papilla for choledocholithiasis in patient with benign duodenal stricture. 61
31163494 2019
45
Early-stage T1b adenocarcinoma arising in the remnant cystic duct after laparoscopic cholecystectomy: a case report and literature review. 61
31783817 2019
46
Choledocholithiasis with spontaneous resolution in infants. 61
31694765 2019
47
Surgical outcomes of ERCP-guided transpapillary gallbladder drainage versus percutaneous cholecystostomy as bridging therapies for acute cholecystitis followed by interval cholecystectomy. 61
31685380 2019
48
Biliary sphincterotomy reduces the risk of acute gallstone pancreatitis recurrence in non-candidates for cholecystectomy. 61
31151894 2019
49
Acute obstructive cholangitis due to fishbone in the common bile duct: a case report and review of the literature. 61
31699035 2019
50
Screening acute cholangitis patients for sepsis. 61
31566288 2019

Variations for Choledocholithiasis

Expression for Choledocholithiasis

Search GEO for disease gene expression data for Choledocholithiasis.

Pathways for Choledocholithiasis

Pathways related to Choledocholithiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.35 GGT2 GGT1 F2 CRP ALB

GO Terms for Choledocholithiasis

Cellular components related to Choledocholithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.61 GUSB GPT GGTLC3 GGT2 GGT1 F2
2 extracellular space GO:0005615 9.28 MIRLET7F2 MIR222 GUSB GPT GGT1 F2

Biological processes related to Choledocholithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 9.43 UGT1A1 F2 CRP
2 zymogen activation GO:0031638 9.37 GGT2 GGT1
3 regulation of immune system process GO:0002682 9.32 GGT2 GGT1
4 peptide modification GO:0031179 9.16 GGT2 GGT1
5 leukotriene D4 biosynthetic process GO:1901750 9.13 GGTLC3 GGT2 GGT1
6 glutathione catabolic process GO:0006751 8.8 GGTLC3 GGT2 GGT1

Molecular functions related to Choledocholithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyltransferase activity GO:0000048 8.96 GGT2 GGT1
2 glutathione hydrolase activity GO:0036374 8.8 GGTLC3 GGT2 GGT1

Sources for Choledocholithiasis

3 CDC
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10 dbSNP
11 DGIdb
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28 GO
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32 ICD10
33 ICD10 via Orphanet
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35 IUPHAR
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44 MESH via Orphanet
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48 NCI
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53 NINDS
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56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
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72 UMLS via Orphanet
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