MCID: CHN009
MIFTS: 30

Chondroid Chordoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Chondroid Chordoma

MalaCards integrated aliases for Chondroid Chordoma:

Name: Chondroid Chordoma 12 15 17 72

Classifications:



External Ids:

Disease Ontology 12 DOID:4152
NCIt 50 C6902
UMLS 72 C1266173

Summaries for Chondroid Chordoma

Disease Ontology : 12 A chordoma that histologically derives from chordoma, derives from chondroma, and derives from chondrosarcoma.

MalaCards based summary : Chondroid Chordoma is related to chordoma and giant cell tumor. An important gene associated with Chondroid Chordoma is VIM (Vimentin), and among its related pathways/superpathways are Cytoskeletal Signaling and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include bone, pituitary and brain.

Related Diseases for Chondroid Chordoma

Diseases related to Chondroid Chordoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 chordoma 31.6 VIM SMARCB1 S100A1 MUC1 CEACAM3
2 giant cell tumor 30.9 VIM SERPINA3 MUC1
3 extraosseous chondrosarcoma 30.7 SMARCB1 ENO2
4 clivus chondroid chordoma 12.9
5 hidradenoma 10.8 VIM MUC1
6 malignant peritoneal mesothelioma 10.7 VIM MUC1
7 syringocystadenoma papilliferum 10.7 VIM MUC1
8 secretory meningioma 10.7 VIM MUC1
9 intravascular papillary endothelial hyperplasia 10.7 VIM SERPINA3
10 parachordoma 10.7 VIM MUC1
11 chordoid meningioma 10.7 VIM MUC1
12 fibrous meningioma 10.7 VIM MUC1
13 eccrine porocarcinoma 10.7 VIM MUC1
14 epulis 10.7 VIM ENO2
15 biphasic synovial sarcoma 10.7 VIM MUC1
16 pilomatrix carcinoma 10.7 MUC1 ENO2
17 intracranial cysts 10.7 MUC1 ENO2
18 endometrial mucinous adenocarcinoma 10.7 VIM MUC1
19 primitive neuroectodermal tumor of the cervix uteri 10.6 VIM ENO2
20 bednar tumor 10.6 VIM ENO2
21 monophasic synovial sarcoma 10.6 VIM MUC1
22 middle ear adenoma 10.6 MUC1 ENO2
23 myxopapillary ependymoma 10.6 VIM MUC1
24 chondrosarcoma 10.6
25 malignant ectomesenchymoma 10.6 S100A1 ENO2
26 clear cell meningioma 10.6 VIM MUC1
27 adenofibroma 10.6 VIM MUC1
28 proliferative fasciitis 10.6 SMARCB1 SERPINA3
29 gallbladder small cell carcinoma 10.6 ENO2 CEACAM3
30 microcystic adenoma 10.6 MUC1 ENO2
31 rhabdoid meningioma 10.6 VIM SMARCB1
32 reticulum cell sarcoma 10.6 VIM S100A1 MUC1
33 syringoma 10.6 VIM MUC1
34 cavernous hemangioma 10.6 VIM S100A1 MUC1
35 malignant fibroxanthoma 10.6 VIM SERPINA3 MUC1
36 astroblastoma 10.5 VIM ENO2
37 large cell carcinoma with rhabdoid phenotype 10.5 SMARCB1 ENO2
38 sinonasal undifferentiated carcinoma 10.5 MUC1 ENO2 CEACAM3
39 ossifying fibromyxoid tumor 10.5 VIM MUC1 ENO2
40 clear cell ependymoma 10.5 VIM MUC1 ENO2
41 ependymoma 10.5 VIM MUC1 ENO2
42 desmoplastic small round cell tumor 10.5 VIM MUC1 ENO2
43 extraskeletal ewing sarcoma 10.5 VIM MUC1 ENO2
44 pleomorphic liposarcoma 10.5 VIM MUC1
45 cerebral primitive neuroectodermal tumor 10.5 VIM MUC1 ENO2
46 cerebellum cancer 10.5 MAP2 ENO2
47 granulosa cell tumor of the ovary 10.5 VIM ENO2 CEACAM3
48 leiomyosarcoma 10.5 VIM S100A1 ENO2
49 epithelioid leiomyosarcoma 10.5 VIM SERPINA3 ENO2
50 epithelioid sarcoma 10.5 VIM SMARCB1 MUC1

Graphical network of the top 20 diseases related to Chondroid Chordoma:



Diseases related to Chondroid Chordoma

Symptoms & Phenotypes for Chondroid Chordoma

Drugs & Therapeutics for Chondroid Chordoma

Search Clinical Trials , NIH Clinical Center for Chondroid Chordoma

Genetic Tests for Chondroid Chordoma

Anatomical Context for Chondroid Chordoma

MalaCards organs/tissues related to Chondroid Chordoma:

41
Bone, Pituitary, Brain, Skin

Publications for Chondroid Chordoma

Articles related to Chondroid Chordoma:

(show top 50) (show all 119)
# Title Authors PMID Year
1
Trends in Primary Brain Tumors: A 5-Year Retrospective Histologically Confirmed Study in Tabriz, Iran, 2011-2016. 38
31143257 2019
2
A unique case of eyelid metastasis from chondroid chordoma. 38
30971557 2019
3
Clival Chondroid Chordoma: A Case Report and Review of the Literature. 38
30519520 2018
4
Clinicopathologic characteristics of poorly differentiated chordoma. 38
29483606 2018
5
Endoscopic transnasal surgery of clival lesions: our experience. 38
29520496 2018
6
Prognostic Factors in Skull Base Chordoma: A Systematic Literature Review and Meta-Analysis. 38
29045855 2018
7
Osteochondroma Presenting as a Calcified Mass in the Sellar Region and Review of the Literature. 38
27903019 2017
8
Chondroblastic osteosarcoma: Cytomorphologic characteristics and differential diagnosis on FNA. 38
26999748 2016
9
A unique case of distant skin metastasis from chondroid chordoma. 38
27051831 2016
10
Nasopharyngeal Masses Arising from Embryologic Remnants of the Clivus: A Case Series. 38
26623237 2015
11
Chondroid chordoma of the sella turcica mimicking a pituitary adenoma. 38
26535833 2015
12
Arrested pneumatization of the sphenoid sinus mimicking intraosseous lesions of the skull base. 38
25793186 2015
13
Skull base chondroid chordoma: atypical case manifesting as intratumoral hemorrhage and literature review. 38
25070287 2014
14
Chondrosarcomas of the head and neck. 38
24213203 2014
15
Sacrococcygeal chordoma presenting as a retro rectal tumour. 38
25201478 2014
16
Chordomas of the upper cervical spine: clinical characteristics and surgical management of a series of 21 patients. 38
25146609 2014
17
Chondroid chordoma in an atypical location. 38
23791243 2013
18
[A case of clivus chordoma with first appearance of sudden deafness]. 38
23002653 2012
19
Maxillary surgical seeding of a clival chordoma. 38
21899379 2012
20
Endoscopic management of a lower clival chondroid chordoma: case report. 38
22274986 2012
21
Chondroid chordoma and nasal adenocarcinoma: an exceptional association. 38
23024872 2012
22
Cervical chondroid chordoma in a standard dachshund: a case report. 38
22017812 2011
23
Endonasal endoscopic approach for the resection of chondroid chordoma with skull base involvement. 38
21959419 2011
24
Intrasellar chondroid chordoma: a case report. 38
22500242 2011
25
Chondroid chordoma of the skull base: immunohistochemical and ultrastructural study of two cases with special reference to microtubules within rough-surfaced endoplasmic reticulum. 38
21267702 2010
26
[Answer September to e-quid. Chondroid chordoma]. 38
21178885 2010
27
Adjuvant radiation therapy and chondroid chordoma subtype are associated with a lower tumor recurrence rate of cranial chordoma. 38
19953297 2010
28
Intradural suprasellar chondroid chordoma. 38
20074956 2010
29
Dumbbell-shaped thoracic chondroid chordoma mimicking a neurinoma. 38
19415177 2010
30
Clinical and histopathologic features of chordomas in children and young adults. 38
19348512 2010
31
Differential diagnosis of dumbbell lesions associated with spinal neural foraminal widening: imaging features. 38
18485652 2009
32
[A case of sacro-coccygeal chondroid chordoma]. 38
19927793 2009
33
Thoracic chordoma: review and role of FDG-PET. 38
18946438 2008
34
A case of coccygeal chondroid chordoma in a cat: morphological and immunohistochemical features. 38
18776111 2008
35
Cervical chondroid chordoma in a Shetland sheep dog. 38
18374350 2008
36
Chondroid chordoma of petrous temporal bone with extensive recurrence and pulmonary metastases. 38
18688126 2008
37
Chondromyxoid fibroma of the temporal bone: case report and review of the literature. 38
18217512 2007
38
Chordoma and chondrosarcoma: similar, but quite different, skull base tumors. 38
17894390 2007
39
Chondroid chordoma of the thoracic spine: case report. 38
17454766 2007
40
Chondroid chordoma of the L5 spinous process and lamina: a case report. 38
15895260 2005
41
[Endoscopic resection of benign and malignant tumors in the nasal cavity and paranasal sinus]. 38
16107047 2005
42
Craniospinal dissemination of clival chondroid chordoma. 38
16333198 2005
43
Radiosurgery for cranial base chordomas and chondrosarcomas. 38
15792516 2005
44
Cytogenetic analysis of three variants of clival chordoma. 38
15474147 2004
45
Chondroid chordoma at the jugular foramen causing retrolabyrinthine lesions in both the cochlear and vestibular branches of the eighth cranial nerve. 38
14763580 2004
46
Primary chondroid chordoma of the petrous part of the temporal bone. 38
14524492 2003
47
Chondroid chordoma of the nasal septum. 38
12578458 2003
48
Petro-cavernous chondroma. CT and MRI features. 38
23648987 2003
49
Chondroid chordoma of the cervical spine. 38
12382136 2002
50
[Pathology of myxoid bone tumors of the skull base]. 38
12410148 2002

Variations for Chondroid Chordoma

Expression for Chondroid Chordoma

Search GEO for disease gene expression data for Chondroid Chordoma.

Pathways for Chondroid Chordoma

GO Terms for Chondroid Chordoma

Cellular components related to Chondroid Chordoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 microtubule GO:0005874 9.56 TUBB4B TUBB2A MTA1 MAP2
2 apical plasma membrane GO:0016324 9.46 PDPN MUC1 EPCAM CEACAM5
3 extracellular exosome GO:0070062 9.28 VIM TUBB4B TUBB2A SERPINA3 MUC1 MFGE8
4 extracellular vesicle GO:1903561 9.13 TUBB4B TUBB2A MFGE8

Biological processes related to Chondroid Chordoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cartilage condensation GO:0001502 9.26 SOX9 ACAN
2 chondrocyte development GO:0002063 9.16 SOX9 ACAN
3 microtubule cytoskeleton organization GO:0000226 9.13 TUBB4B TUBB2A MAP2
4 positive regulation of histone H4 acetylation GO:0090240 8.62 SMARCB1 MUC1

Molecular functions related to Chondroid Chordoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.8 VIM TUBB4B TUBB2A

Sources for Chondroid Chordoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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