MCID: CHR033
MIFTS: 31

Chordoid Glioma

Categories: Bone diseases, Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Chordoid Glioma

MalaCards integrated aliases for Chordoid Glioma:

Name: Chordoid Glioma 12 58 15
Chordoid Glioma of the Third Ventricle 70

Characteristics:

Orphanet epidemiological data:

58
chordoid glioma
Age of onset: Adult; Age of death: adult;

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:3774
NCIt 50 C5592
SNOMED-CT 67 128789002
ICD10 via Orphanet 33 C71.9
Orphanet 58 ORPHA251674
UMLS 70 C1322252

Summaries for Chordoid Glioma

MalaCards based summary : Chordoid Glioma, also known as chordoid glioma of the third ventricle, is related to third ventricle chordoid glioma and obstructive hydrocephalus. An important gene associated with Chordoid Glioma is PRKCA (Protein Kinase C Alpha), and among its related pathways/superpathways are Neuroscience and Spinal Cord Injury. Affiliated tissues include brain, eye and thyroid, and related phenotypes are Increased proliferation and neoplasm

Related Diseases for Chordoid Glioma

Diseases related to Chordoid Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 473)
# Related Disease Score Top Affiliating Genes
1 third ventricle chordoid glioma 32.9 NKX2-1 GFAP
2 obstructive hydrocephalus 30.5 SYP NF2 GFAP
3 benign ependymoma 30.4 SYP NF2 GFAP
4 hydrocephalus 30.4 TP53 SYP S100B GFAP
5 secretory meningioma 30.4 NF2 MUC1 KRT7
6 astroblastoma 30.1 SYP MUC1 GFAP
7 cellular ependymoma 29.9 SYP S100B NF2 MUC1 GFAP
8 gliomatosis cerebri 29.8 TP53 SYP GFAP
9 chordoma 29.8 TP53 S100B MUC1 KRT7 GFAP
10 chordoid meningioma 29.6 SYP S100B NF2 MUC1 GFAP
11 oncocytoma 29.6 SYP NKX2-1 MUC1 KRT7
12 central nervous system cancer 29.4 TP53 SYP NF2 GFAP
13 meningioma, familial 28.7 TP53 SYP S100B PGR NF2 MUC1
14 glioma 10.9
15 glial tumor 10.9
16 rare tumor 10.5
17 diabetes insipidus 10.4
18 sclerosing perineurioma 10.4 S100B MUC1
19 localized hypertrophic neuropathy 10.4 S100B MUC1
20 reticular perineurioma 10.3 S100B MUC1
21 aggressive digital papillary adenocarcinoma 10.3 S100B MUC1
22 meningeal melanocytoma 10.3 S100B MUC1
23 cerebral primitive neuroectodermal tumor 10.3 S100B MUC1
24 non-functioning pituitary adenoma 10.3 S100B MUC1
25 epithelioid malignant peripheral nerve sheath tumor 10.3 S100B MUC1
26 ossifying fibromyxoid tumor 10.3 S100B MUC1
27 polymorphous low-grade adenocarcinoma 10.3 S100B MUC1
28 lung sarcomatoid carcinoma 10.3 NKX2-1 MUC1
29 esophageal neuroendocrine tumor 10.3 SYP MUC1
30 sinonasal undifferentiated carcinoma 10.3 SYP MUC1
31 papillary tumor of the pineal region 10.3 SYP MUC1
32 intracranial meningioma 10.3
33 lymphoplasmacyte-rich meningioma 10.3
34 vulvar eccrine porocarcinoma 10.3 SYP MUC1
35 dendritic cell tumor 10.3 S100B MUC1
36 primary hepatic neuroendocrine carcinoma 10.3 SYP S100B
37 posterior pituitary gland neoplasm 10.3 NKX2-1 GFAP
38 hypoganglionosis 10.3 SYP S100B
39 rosette-forming glioneuronal tumor 10.2 SYP S100B
40 scrotum paget's disease 10.2 MUC1 KRT7
41 traumatic brain injury 10.2 S100B GFAP
42 brain injury 10.2 S100B GFAP
43 extraventricular neurocytoma 10.2 SYP GFAP
44 gallbladder signet ring cell adenocarcinoma 10.2 MUC1 KRT7
45 malignant peritoneal mesothelioma 10.2 NF2 MUC1
46 desmoplastic infantile ganglioglioma 10.2 SYP GFAP
47 cerebral neuroblastoma 10.2 SYP GFAP
48 lung combined type small cell carcinoma 10.2 SYP GFAP
49 urinary bladder villous adenoma 10.2 MUC1 KRT7
50 mucinous intrahepatic cholangiocarcinoma 10.2 MUC1 KRT7

Graphical network of the top 20 diseases related to Chordoid Glioma:



Diseases related to Chordoid Glioma

Symptoms & Phenotypes for Chordoid Glioma

GenomeRNAi Phenotypes related to Chordoid Glioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 TP53

MGI Mouse Phenotypes related to Chordoid Glioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.35 NF2 NKX2-1 PGR PRKCA TP53
2 normal MP:0002873 9.1 GFAP NKX2-1 PGR S100B SYP TP53

Drugs & Therapeutics for Chordoid Glioma

Search Clinical Trials , NIH Clinical Center for Chordoid Glioma

Genetic Tests for Chordoid Glioma

Anatomical Context for Chordoid Glioma

MalaCards organs/tissues related to Chordoid Glioma:

40
Brain, Eye, Thyroid, Pineal, Hypothalamus

Publications for Chordoid Glioma

Articles related to Chordoid Glioma:

(show top 50) (show all 115)
# Title Authors PMID Year
1
Chordoid Glioma With Dot-Like Immunoreactivity for Synaptophysin. 61
33786244 2021
2
One of a kind-chordoid glioma in the fourth ventricle: a case report and literature review. 61
33403125 2020
3
PRKCA D463H Mutation in Chordoid Glioma of the Third Ventricle: A Cohort of 16 Cases, Including Two Cases Harboring BRAFV600E Mutation. 61
33085976 2020
4
Intracranial chordoid glioma: A clinical, radiological and pathological study of 14 cases. 61
33099359 2020
5
Chordoid glioma: an entity occurring not exclusively in the third ventricle. 61
31422571 2020
6
A Rare Instance of Chordoid Glioma With Large Calcification Mimicking Craniopharyngioma. 61
31895860 2020
7
Chordoid Glioma of the Third Ventricle: A Case Report and a Treatment Strategy to This Rare Tumor. 61
32328466 2020
8
Chordoid Glioma Infiltrating Optic Structures. 61
30829943 2019
9
Chordoid Glioma of the Third Ventricle. 61
31512680 2019
10
Chordoid Glioma as a Differential Diagnosis of Anterior Third Ventricle Tumours: A Rare Case Report and Five-Year Follow-Up. 61
31871814 2019
11
MRI of intracranial intraventricular lesions. 61
30138862 2018
12
Chordoid Glioma with Psychosis: Case Report. 61
30188563 2018
13
Epithelial differentiation with microlumen formation in meningioma: diagnostic utility of NHERF1/EBP50 immunohistochemistry. 61
29983887 2018
14
Letter to the editor regarding "The trans-laminar terminalis approach reduces mortalities associated with chordoid glioma resections: A case report and a review of 20 years of literature". 61
29605280 2018
15
A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas. 61
29915258 2018
16
Gross Total Resection of Chordoid Glioma of the Third Ventricle via Anterior Interhemispheric Transcallosal Transforaminal Approach at Two Stages. 61
29588902 2018
17
A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. 61
29476136 2018
18
The trans-laminar terminalis approach reduces mortalities associated with chordoid glioma resections: A case report and a review of 20 years of literature. 61
29066234 2018
19
Usefulness of neuroimaging and immunohistochemical study for accurate diagnosis of chordoid glioma of the third ventricle: A case report and review of the literature. 61
30533273 2018
20
Suprasellar chordoid glioma: a report of two cases. 61
30624507 2018
21
[Lateral Ventricular Chordoid Glioma in a Pediatric Patient: a Case Report]. 61
29262517 2017
22
Management in chordoid glioma: Avoiding the pitfalls in this rare and challenging entity. 61
28681757 2017
23
Chordoid Glioma: A Neoplasm Found in the Anterior Part of the Third Ventricle. 61
28708638 2017
24
Chordoid glioma: A new paradigm of hypothalamic dysfunction? 61
27798757 2017
25
Chordoid glioma of the third ventricle: report of a rapidly progressive case. 61
28315998 2017
26
[A case report of chordoid glioma with unusual features: Immunohistochemical and molecular findings and differential diagnoses]. 61
28285812 2017
27
Concurrence of chordoid gliomas with Rosai-Dorfman component: report of two rare cases. 61
31966479 2017
28
Expanded Endoscopic Transnasal Approach to the Chordoid Glioma of the Third Ventricle : The First Case Ever Reported. 61
27847580 2016
29
Neurogenic fever in a patient with a chordoid glioma. 61
27856533 2016
30
Chordoid Glioma of Third Ventricle With an Epidermoid Cyst: Coexistence or Common Histogenesis? 61
27194402 2016
31
Chordoid glioma of the third ventricle: a patient presenting with SIADH and a review of this rare tumor. 61
26879322 2016
32
[Clinicopathologic study of chordoid glioma of third ventricle: a report of 5 cases]. 61
27510786 2016
33
Corrigendum to "The radiological findings of chordoid glioma: report of two cases, one case with MR spectroscopy" [Clin Imaging 39 (2015) 1086-1089]. 61
27133706 2016
34
Chordoid Glioma with Intraventricular Dissemination: A Case Report with Perfusion MR Imaging Features. 61
26798226 2016
35
Rare glial tumors. 61
26948368 2016
36
Chordoid glioma. 61
26668411 2015
37
The radiological findings of chordoid glioma: report of two cases, one case with MR spectroscopy. 61
26275847 2015
38
Chordoid glioma of the third ventricle. 61
26543291 2015
39
Chordoid gliomas of the third ventricle share TTF-1 expression with organum vasculosum of the lamina terminalis. 61
25786084 2015
40
Suprasellar chordoid neoplasm with expression of thyroid transcription factor 1: evidence that chordoid glioma of the third ventricle and pituicytoma may form part of a spectrum of lineage-related tumors of the basal forebrain. 61
25934249 2015
41
Chordoid glioma: a rare radiologically, histologically, and clinically mystifying lesion. 61
26018908 2015
42
Chordoid glioma: Case report and review of the literature. 61
25648470 2015
43
Expression of thyroid transcription factor 1 in a chordoid glioma. 61
25248954 2014
44
Neuro-ophthalmologic features of chordoid glioma. 61
24113763 2014
45
Anterior callosal section is useful for the removal of large tumors invading the dorsal part of the anterior third ventricle: operative technique and results. 61
23568695 2013
46
Chordoid glioma of the third ventricle: four cases including one case with papillary features. 61
22716306 2013
47
Molecular characterization of circumventricular organs and third ventricle ependyma in the rat: potential markers for periventricular tumors. 61
22537279 2013
48
From the radiologic pathology archives: intraventricular neoplasms: radiologic-pathologic correlation. 61
23322825 2013
49
Therapeutic approach to chordoid glioma of the third ventricle. 61
23615418 2013
50
[The MRI findings in chordoid glioma of the third ventricle]. 61
23660212 2013

Variations for Chordoid Glioma

Expression for Chordoid Glioma

Search GEO for disease gene expression data for Chordoid Glioma.

Pathways for Chordoid Glioma

Pathways related to Chordoid Glioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 SYP S100B NKX2-1 NF2 GFAP
2 11.51 TP53 PRKCA GFAP
3
Show member pathways
11.37 S100B PGR GFAP
4 11.03 SYP S100B GFAP

GO Terms for Chordoid Glioma

Biological processes related to Chordoid Glioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.96 TP53 MUC1
2 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 8.62 TP53 MUC1

Molecular functions related to Chordoid Glioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 8.92 TP53 PRKCA PGR NKX2-1

Sources for Chordoid Glioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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