MCID: CHR055
MIFTS: 32

Chordoid Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Chordoid Meningioma

MalaCards integrated aliases for Chordoid Meningioma:

Name: Chordoid Meningioma 12 15 73
Meningioma, Chordoid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8368
NCIt 50 C6908
SNOMED-CT 68 399709001 57606003
UMLS 73 C1370510

Summaries for Chordoid Meningioma

MalaCards based summary : Chordoid Meningioma, also known as meningioma, chordoid, is related to chordoma and myxopapillary ependymoma. An important gene associated with Chordoid Meningioma is SYP (Synaptophysin), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Trabectedin and Alkylating Agents have been mentioned in the context of this disorder. Affiliated tissues include pineal and lung.

Related Diseases for Chordoid Meningioma

Diseases related to Chordoid Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 224)
# Related Disease Score Top Affiliating Genes
1 chordoma 28.9 GFAP MUC1 S100B VIM
2 myxopapillary ependymoma 28.7 GFAP MUC1 S100B VIM
3 tuberous sclerosis 28.0 GFAP S100B SYP VIM
4 ependymoma 27.3 GFAP MUC1 S100B SYP VIM
5 cutaneous leiomyosarcoma 10.6 GFAP MUC1
6 malignant peritoneal mesothelioma 10.5 MUC1 VIM
7 malignant mixed mullerian tumor 10.5 MUC1 VIM
8 nodular hidradenoma 10.5 MUC1 VIM
9 endometrial mucinous adenocarcinoma 10.5 MUC1 VIM
10 biphasic synovial sarcoma 10.5 MUC1 VIM
11 adenofibroma 10.4 MUC1 VIM
12 primitive neuroectodermal tumor of the cervix uteri 10.4 GFAP VIM
13 hidradenoma 10.4 MUC1 VIM
14 reticulum cell sarcoma 10.4 MUC1 VIM
15 mucinous cystadenocarcinoma 10.4 MUC1 VIM
16 mesenchymal chondrosarcoma 10.4 MUC1 VIM
17 ependymoblastoma 10.4 GFAP VIM
18 chondroid chordoma 10.4 MUC1 VIM
19 localized hypertrophic neuropathy 10.4 MUC1 S100B
20 sclerosing perineurioma 10.4 MUC1 S100B
21 reticular perineurioma 10.4 MUC1 S100B
22 non-functioning pituitary adenoma 10.4 MUC1 S100B
23 benign mesothelioma 10.3 MUC1 VIM
24 signet ring cell adenocarcinoma 10.3 CHGA MUC1
25 tubular adenocarcinoma 10.3 CHGA MUC1
26 aggressive digital papillary adenocarcinoma 10.3 MUC1 S100B
27 papillary adenocarcinoma 10.3 MUC1 VIM
28 secretory meningioma 10.3 MUC1 VIM
29 pericardial mesothelioma 10.3 MUC1 VIM
30 osteofibrous dysplasia 10.3 MUC1 VIM
31 fasciitis 10.3 MUC1 VIM
32 gemistocytic astrocytoma 10.3 GFAP S100B
33 epithelioid sarcoma 10.3 MUC1 VIM
34 functioning pituitary adenoma 10.3 MUC1 S100B
35 syndrome of inappropriate antidiuretic hormone 10.3 CHGA VIM
36 meningeal melanocytoma 10.3 MUC1 S100B
37 pneumothorax 10.3 MUC1 VIM
38 angiosarcoma 10.2 MUC1 VIM
39 endodermal sinus tumor 10.2 CHGA VIM
40 hydromyelia 10.2 S100B VIM
41 bednar tumor 10.2 S100B VIM
42 intraneural perineurioma 10.2 MUC1 S100B
43 cystadenocarcinoma 10.2 MUC1 VIM
44 traumatic brain injury 10.2 GFAP S100B
45 juvenile xanthogranuloma 10.2 S100B VIM
46 pilomatrixoma 10.2 MUC1 S100B
47 cutaneous fibrous histiocytoma 10.2 S100B VIM
48 odontogenic myxoma 10.1 S100B VIM
49 sinonasal undifferentiated carcinoma 10.1 MUC1 SYP
50 embryonal sarcoma 10.1 S100B VIM

Graphical network of the top 20 diseases related to Chordoid Meningioma:



Diseases related to Chordoid Meningioma

Symptoms & Phenotypes for Chordoid Meningioma

Drugs & Therapeutics for Chordoid Meningioma

Drugs for Chordoid Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Trabectedin Approved, Investigational Phase 2 114899-77-3 108150
2 Alkylating Agents Phase 2
3 Antineoplastic Agents, Alkylating Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Trabectedin for Recurrent Grade II/III Meningioma Active, not recruiting NCT02234050 Phase 2 Trabectedin
2 Oncological Care for Patients With Meningioma Not yet recruiting NCT02973256

Search NIH Clinical Center for Chordoid Meningioma

Genetic Tests for Chordoid Meningioma

Anatomical Context for Chordoid Meningioma

MalaCards organs/tissues related to Chordoid Meningioma:

41
Pineal, Lung

Publications for Chordoid Meningioma

Articles related to Chordoid Meningioma:

(show top 50) (show all 76)
# Title Authors Year
1
A thoracic extradural chordoid meningioma: a unique case report and literature review. ( 29355032 )
2018
2
Chordoid meningioma: a clinico-pathological study of an uncommon variant of meningioma. ( 29380221 )
2018
3
Chromosomal aberrations in chordoid meningioma - An analysis. ( 29322978 )
2018
4
Innate immunity may play a role in growth and relapse of chordoid meningioma. ( 28885077 )
2017
5
Chordoid Meningioma - A Case Report: Clinicopathological Features and Differential Diagnosis of an Uncommon Tumor. ( 24715552 )
2016
6
Expanded Endoscopic Transclival Approach for Resection of a Chordoid Meningioma Without Dural Attachment (MWODA) Located in the Prepontine Cistern. ( 27155376 )
2016
7
Clinical features, treatment and prognostic factors of chordoid meningioma. ( 27060511 )
2016
8
Dedifferentiated chordoid meningioma with rhabdomyosarcomatous differentiation on the middle cranial fossa. ( 27910213 )
2016
9
Utility of diff-quik stained smears in the cytologic diagnosis of chordoid meningioma. ( 27534736 )
2016
10
Spinal chordoid meningioma in a child: A case report and review of the literature. ( 26788198 )
2015
11
Predictors of recurrence in the management of chordoid meningioma. ( 26409888 )
2015
12
Chordoid Meningioma: Differentiating a Rare World Health Organization Grade II Tumor from Other Meningioma Histologic Subtypes Using MRI. ( 25882286 )
2015
13
Chordoid meningioma: A diagnostic dilemma. ( 26458690 )
2015
14
Chordoid meningioma in a pediatric patient with tuberous sclerosis complex. ( 25214863 )
2014
15
Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: case report and literature review. ( 22784446 )
2013
16
Chordoid meningioma in an adult patient presenting with chronic fatigue and systemic inflammation. ( 24635333 )
2013
17
Chordoid meningioma: a retrospective series of seven consecutive cases. ( 23595544 )
2013
18
Clinical features and treatment of intracranial chordoid meningioma: a report of 30 cases. ( 23617629 )
2013
19
Chordoid meningioma, part of a multiple intracranial meningioma: a case report & review. ( 24044003 )
2013
20
Chordoid meningioma: a retrospective study of 17 cases at a single institution. ( 23422207 )
2013
21
Intraparenchymal chordoid meningioma: a case report and review of the literature. ( 22689613 )
2012
22
A clinicopathological study of the significance of the proportion of choroid morphology in chordoid meningioma. ( 22516546 )
2012
23
Intraventricular chordoid meningioma in a child: fever of unknown origin, clinical course, and response to treatment. ( 23061820 )
2012
24
Chordoid meningioma in a patient with lymphangioleiomyomatosis. ( 21643986 )
2011
25
Primary chordoid meningioma of the lung. ( 20634760 )
2011
26
Report of two cases of chordoid meningioma in patients with Castleman syndrome. ( 21136280 )
2011
27
Chordoid meningioma of the third ventricle: a case report and review of the literature. ( 21329615 )
2011
28
Intraparenchymal cystic chordoid meningioma: a case report and review of the literature. ( 21481008 )
2011
29
Anterior temporal chordoid meningioma causing compressive optic neuropathy. ( 21358445 )
2011
30
Fourth ventricular chordoid meningioma. ( 20673720 )
2010
31
A primary optic nerve sheath chordoid meningioma. ( 20074963 )
2010
32
Giant chordoid meningioma symptomatic immediately after pregnancy: report of a rare case. ( 20423691 )
2010
33
Castleman's disease associated with a cerebellar chordoid meningioma and intestinal lymphangiectasia. ( 20567835 )
2010
34
Chordoid meningioma: a report of ten cases. ( 20094774 )
2010
35
Chordoid meningioma: a clinicopathologic study of 11 cases at a single institution. ( 20454999 )
2010
36
Cytopathologic features of orbital intraosseous chordoid meningioma: report of a case and distinction from other myxoid/mucoid tumors. ( 20091894 )
2010
37
Distinguishing chordoid meningiomas from their histologic mimics: an immunohistochemical evaluation. ( 19194275 )
2009
38
Immunohistochemical comparison of chordoma with chondrosarcoma, myxopapillary ependymoma, and chordoid meningioma. ( 19521276 )
2009
39
Comparative analysis of proliferative and genetic alterations in a primary chordoid meningioma and its recurrence using locus-specific probes and AgNOR. ( 21475849 )
2009
40
Ultrastructural and immunohistochemical study of an adult case of chordoid meningioma. ( 19408096 )
2009
41
Evaluation of neo-angiogenesis in a case of chordoid meningioma. ( 19557500 )
2009
42
Chordoid meningioma arising in the pineal region: a case report. ( 18987835 )
2008
43
Chordoid meningioma of the foramen magnum in a child: a case report and review of the literature. ( 18214497 )
2008
44
Chordoid meningioma presenting as painful orbital apex syndrome in pregnancy. ( 17898939 )
2008
45
Third ventricular chordoid meningioma in a child. ( 18831662 )
2008
46
Chordoid meningioma: presentation of two case reports, review of the literature, and plea for data standardisation. ( 18320142 )
2008
47
Infiltrative chordoid meningioma of the pineal region: a study of 2 cases. ( 19157002 )
2007
48
Chordoid meningioma: a report of two cases. ( 17517194 )
2007
49
Orbital chordoid meningioma: a rare subtype of meningioma. ( 17519674 )
2007
50
Cytology of chordoid meningioma: a series of five cases with emphasis on differential diagnoses. ( 16837627 )
2007

Variations for Chordoid Meningioma

Expression for Chordoid Meningioma

Search GEO for disease gene expression data for Chordoid Meningioma.

Pathways for Chordoid Meningioma

Pathways related to Chordoid Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 GFAP S100B SYP
2 10.82 GFAP S100B SYP VIM

GO Terms for Chordoid Meningioma

Biological processes related to Chordoid Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 9.4 GFAP VIM
2 long-term synaptic potentiation GO:0060291 9.37 GFAP S100B
3 regulation of neuronal synaptic plasticity GO:0048168 9.32 S100B SYP
4 astrocyte development GO:0014002 9.26 GFAP VIM
5 intermediate filament organization GO:0045109 9.16 GFAP VIM
6 Bergmann glial cell differentiation GO:0060020 8.96 GFAP VIM
7 intermediate filament-based process GO:0045103 8.62 GFAP VIM

Molecular functions related to Chordoid Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 GFAP S100B SYP VIM

Sources for Chordoid Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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