MCID: CHR055
MIFTS: 33

Chordoid Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Chordoid Meningioma

MalaCards integrated aliases for Chordoid Meningioma:

Name: Chordoid Meningioma 12 15 73
Meningioma, Chordoid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8368
NCIt 50 C6908
SNOMED-CT 68 57606003
UMLS 73 C1370510

Summaries for Chordoid Meningioma

MalaCards based summary : Chordoid Meningioma, also known as meningioma, chordoid, is related to secretory meningioma and chordoma. An important gene associated with Chordoid Meningioma is SYP (Synaptophysin), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Trabectedin and Alkylating Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, pineal and lung.

Related Diseases for Chordoid Meningioma

Diseases related to Chordoid Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 230)
# Related Disease Score Top Affiliating Genes
1 secretory meningioma 30.2 MUC1 VIM
2 chordoma 29.9 GFAP MUC1 S100B VIM
3 myxopapillary ependymoma 29.7 GFAP MUC1 S100B VIM
4 tuberous sclerosis 29.4 GFAP S100B SYP VIM
5 ependymoma 29.2 GFAP MUC1 S100B SYP VIM
6 sarcoma, synovial 10.2 MUC1 VIM
7 osteofibrous dysplasia 10.2 MUC1 VIM
8 giant cell tumor 10.2 MUC1 VIM
9 mucinous cystadenocarcinoma 10.2 MUC1 VIM
10 signet ring cell adenocarcinoma 10.2 CHGA MUC1
11 chondroid chordoma 10.2 MUC1 VIM
12 carcinosarcoma 10.2 MUC1 VIM
13 mucoepidermoid carcinoma 10.2 CHGA MUC1
14 epithelioid sarcoma 10.2 MUC1 VIM
15 pericardial mesothelioma 10.2 MUC1 VIM
16 gastric cardia carcinoma 10.2 CHGA MUC1
17 fasciitis 10.2 MUC1 VIM
18 pilomatrixoma 10.1 MUC1 S100B
19 intraneural perineurioma 10.1 MUC1 S100B
20 malignant peritoneal mesothelioma 10.1 MUC1 VIM
21 endodermal sinus tumor 10.1 CHGA VIM
22 meningeal melanocytoma 10.1 MUC1 S100B
23 syndrome of inappropriate antidiuretic hormone 10.1 CHGA VIM
24 nodular hidradenoma 10.1 MUC1 VIM
25 neuronal ceroid-lipofuscinoses 10.1 GFAP S100B
26 brain injury 10.1 GFAP S100B
27 traumatic brain injury 10.1 GFAP S100B
28 hidradenoma 10.1 MUC1 VIM
29 primitive neuroectodermal tumor of the cervix uteri 10.1 GFAP VIM
30 cutaneous leiomyosarcoma 10.1 GFAP VIM
31 endometrial mucinous adenocarcinoma 10.1 MUC1 VIM
32 bile duct adenoma 10.1 MUC1 VIM
33 biphasic synovial sarcoma 10.1 MUC1 VIM
34 papillary adenocarcinoma 10.1 MUC1 VIM
35 rhabdoid meningioma 10.1 GFAP VIM
36 localized hypertrophic neuropathy 10.1 MUC1 S100B
37 adenofibroma 10.1 MUC1 VIM
38 sclerosing perineurioma 10.1 MUC1 S100B
39 angiosarcoma 10.1 MUC1 VIM
40 reticular perineurioma 10.1 MUC1 S100B
41 dermatofibrosarcoma protuberans 10.1 S100B VIM
42 inflammatory myofibroblastic tumor 10.1 S100B VIM
43 neuroma 10.1 GFAP S100B
44 non-functioning pituitary adenoma 10.1 MUC1 S100B
45 functioning pituitary adenoma 10.1 MUC1 S100B
46 embryonal sarcoma 10.1 S100B VIM
47 hidradenocarcinoma 10.1 S100B VIM
48 odontogenic myxoma 10.1 S100B VIM
49 osteochondroma 10.1 S100B VIM
50 ependymoblastoma 10.1 GFAP VIM

Graphical network of the top 20 diseases related to Chordoid Meningioma:



Diseases related to Chordoid Meningioma

Symptoms & Phenotypes for Chordoid Meningioma

Drugs & Therapeutics for Chordoid Meningioma

Drugs for Chordoid Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Trabectedin Approved, Investigational Phase 2 114899-77-3 108150
2 Alkylating Agents Phase 2
3 Antineoplastic Agents, Alkylating Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Trabectedin for Recurrent Grade II/III Meningioma Active, not recruiting NCT02234050 Phase 2 Trabectedin
2 Oncological Care for Patients With Meningioma Not yet recruiting NCT02973256

Search NIH Clinical Center for Chordoid Meningioma

Genetic Tests for Chordoid Meningioma

Anatomical Context for Chordoid Meningioma

MalaCards organs/tissues related to Chordoid Meningioma:

41
Brain, Pineal, Lung, Kidney, Pituitary, Cervix, Thymus

Publications for Chordoid Meningioma

Articles related to Chordoid Meningioma:

(show top 50) (show all 77)
# Title Authors Year
1
A thoracic extradural chordoid meningioma: a unique case report and literature review. ( 29355032 )
2018
2
Chordoid meningioma: a clinico-pathological study of an uncommon variant of meningioma. ( 29380221 )
2018
3
Chromosomal aberrations in chordoid meningioma - An analysis. ( 29322978 )
2018
4
Foramen Magnum Chordoid Meningioma in a 22-Year-old Female. ( 30283559 )
2018
5
Innate immunity may play a role in growth and relapse of chordoid meningioma. ( 28885077 )
2017
6
Chordoid Meningioma - A Case Report: Clinicopathological Features and Differential Diagnosis of an Uncommon Tumor. ( 24715552 )
2016
7
Expanded Endoscopic Transclival Approach for Resection of a Chordoid Meningioma Without Dural Attachment (MWODA) Located in the Prepontine Cistern. ( 27155376 )
2016
8
Clinical features, treatment and prognostic factors of chordoid meningioma. ( 27060511 )
2016
9
Dedifferentiated chordoid meningioma with rhabdomyosarcomatous differentiation on the middle cranial fossa. ( 27910213 )
2016
10
Utility of diff-quik stained smears in the cytologic diagnosis of chordoid meningioma. ( 27534736 )
2016
11
Spinal chordoid meningioma in a child: A case report and review of the literature. ( 26788198 )
2015
12
Predictors of recurrence in the management of chordoid meningioma. ( 26409888 )
2015
13
Chordoid Meningioma: Differentiating a Rare World Health Organization Grade II Tumor from Other Meningioma Histologic Subtypes Using MRI. ( 25882286 )
2015
14
Chordoid meningioma: A diagnostic dilemma. ( 26458690 )
2015
15
Erratum to: Predictors of recurrence in the management of chordoid meningioma. ( 26493739 )
2015
16
Chordoid meningioma in a pediatric patient with tuberous sclerosis complex. ( 25214863 )
2014
17
Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: case report and literature review. ( 22784446 )
2013
18
Chordoid meningioma in an adult patient presenting with chronic fatigue and systemic inflammation. ( 24635333 )
2013
19
Chordoid meningioma: a retrospective series of seven consecutive cases. ( 23595544 )
2013
20
Clinical features and treatment of intracranial chordoid meningioma: a report of 30 cases. ( 23617629 )
2013
21
Chordoid meningioma, part of a multiple intracranial meningioma: a case report & review. ( 24044003 )
2013
22
Chordoid meningioma: a retrospective study of 17 cases at a single institution. ( 23422207 )
2013
23
Intraparenchymal chordoid meningioma: a case report and review of the literature. ( 22689613 )
2012
24
A clinicopathological study of the significance of the proportion of choroid morphology in chordoid meningioma. ( 22516546 )
2012
25
Intraventricular chordoid meningioma in a child: fever of unknown origin, clinical course, and response to treatment. ( 23061820 )
2012
26
Chordoid meningioma in a patient with lymphangioleiomyomatosis. ( 21643986 )
2011
27
Primary chordoid meningioma of the lung. ( 20634760 )
2011
28
Report of two cases of chordoid meningioma in patients with Castleman syndrome. ( 21136280 )
2011
29
Chordoid meningioma of the third ventricle: a case report and review of the literature. ( 21329615 )
2011
30
Intraparenchymal cystic chordoid meningioma: a case report and review of the literature. ( 21481008 )
2011
31
Anterior temporal chordoid meningioma causing compressive optic neuropathy. ( 21358445 )
2011
32
Fourth ventricular chordoid meningioma. ( 20673720 )
2010
33
A primary optic nerve sheath chordoid meningioma. ( 20074963 )
2010
34
Giant chordoid meningioma symptomatic immediately after pregnancy: report of a rare case. ( 20423691 )
2010
35
Castleman's disease associated with a cerebellar chordoid meningioma and intestinal lymphangiectasia. ( 20567835 )
2010
36
Chordoid meningioma: a report of ten cases. ( 20094774 )
2010
37
Chordoid meningioma: a clinicopathologic study of 11 cases at a single institution. ( 20454999 )
2010
38
Cytopathologic features of orbital intraosseous chordoid meningioma: report of a case and distinction from other myxoid/mucoid tumors. ( 20091894 )
2010
39
Immunohistochemical comparison of chordoma with chondrosarcoma, myxopapillary ependymoma, and chordoid meningioma. ( 19521276 )
2009
40
Comparative analysis of proliferative and genetic alterations in a primary chordoid meningioma and its recurrence using locus-specific probes and AgNOR. ( 21475849 )
2009
41
Ultrastructural and immunohistochemical study of an adult case of chordoid meningioma. ( 19408096 )
2009
42
Evaluation of neo-angiogenesis in a case of chordoid meningioma. ( 19557500 )
2009
43
Chordoid meningioma arising in the pineal region: a case report. ( 18987835 )
2008
44
Chordoid meningioma of the foramen magnum in a child: a case report and review of the literature. ( 18214497 )
2008
45
Chordoid meningioma presenting as painful orbital apex syndrome in pregnancy. ( 17898939 )
2008
46
Third ventricular chordoid meningioma in a child. ( 18831662 )
2008
47
Chordoid meningioma: presentation of two case reports, review of the literature, and plea for data standardisation. ( 18320142 )
2008
48
Infiltrative chordoid meningioma of the pineal region: a study of 2 cases. ( 19157002 )
2007
49
Chordoid meningioma: a report of two cases. ( 17517194 )
2007
50
Orbital chordoid meningioma: a rare subtype of meningioma. ( 17519674 )
2007

Variations for Chordoid Meningioma

Expression for Chordoid Meningioma

Search GEO for disease gene expression data for Chordoid Meningioma.

Pathways for Chordoid Meningioma

Pathways related to Chordoid Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 GFAP S100B SYP
2 10.82 GFAP S100B SYP VIM

GO Terms for Chordoid Meningioma

Biological processes related to Chordoid Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 9.4 GFAP VIM
2 long-term synaptic potentiation GO:0060291 9.37 GFAP S100B
3 regulation of neuronal synaptic plasticity GO:0048168 9.32 S100B SYP
4 intermediate filament organization GO:0045109 9.26 GFAP VIM
5 astrocyte development GO:0014002 9.16 GFAP VIM
6 Bergmann glial cell differentiation GO:0060020 8.96 GFAP VIM
7 intermediate filament-based process GO:0045103 8.62 GFAP VIM

Molecular functions related to Chordoid Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 GFAP S100B SYP VIM

Sources for Chordoid Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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