MCID: CHR010
MIFTS: 37

Chorioangioma

Categories: Cancer diseases, Fetal diseases, Reproductive diseases

Aliases & Classifications for Chorioangioma

MalaCards integrated aliases for Chorioangioma:

Name: Chorioangioma 12 15 73
Placental Hemangioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:277
MeSH 44 D006391
NCIt 50 C4868
SNOMED-CT 68 2099007
UMLS 73 C0677608

Summaries for Chorioangioma

MalaCards based summary : Chorioangioma, also known as placental hemangioma, is related to hydrops fetalis, nonimmune, and/or atrial septal defect and fetal edema. An important gene associated with Chorioangioma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Glioma and Wnt / Hedgehog / Notch. Affiliated tissues include placenta, heart and liver, and related phenotypes are Decreased human papilloma virus 16 (HPV16) pseudovirus infection and Decreased telomerase activity

Wikipedia : 76 Chorioangioma (Placental hemangioma) is a benign tumor of placenta. It is seen in approximately 0.5 to... more...

Related Diseases for Chorioangioma

Diseases related to Chorioangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 hydrops fetalis, nonimmune, and/or atrial septal defect 10.4
2 fetal edema 10.4
3 hydrops fetalis 10.4
4 polyhydramnios 10.4
5 sclerosing hepatic carcinoma 10.2 AFP PTHLH
6 liver sarcoma 10.2 AFP PTHLH
7 discrete subaortic stenosis 10.2 CRELD1 NOTCH1
8 ovarian solid teratoma 10.2 AFP CD34
9 malignant pineal area germ cell neoplasm 10.2 AFP CD34
10 chromosomal disease 10.2 AFP APPL1 CRELD1
11 liver inflammatory pseudotumor 10.1 AFP CD34
12 liver lymphoma 10.1 AFP FUT4
13 invasive malignant thymoma 10.1 CD34 PTHLH
14 skin epithelioid hemangioma 10.1 CD34 HBA1
15 ovary sarcoma 10.1 CD34 HBA1
16 ovarian angiosarcoma 10.1 CD34 HBA1
17 subclavian steal syndrome 10.1 IL24 NOTCH1
18 intravascular fasciitis 10.1 CD34 HBA1
19 pediatric angiosarcoma 10.1 CD34 HBA1
20 thyroid angiosarcoma 10.1 CD34 HBA1
21 spleen angiosarcoma 10.1 CD34 HBA1
22 bone epithelioid hemangioma 10.1 CD34 HBA1
23 hemangioma 10.1
24 thrombocytopenia 10.1
25 thyroid sarcoma 10.1 CD34 HBA1
26 hobnail hemangioma 10.1 CD34 HBA1
27 hordeolum 10.1 CD34 HBA1
28 glomeruloid hemangioma 10.1 CD34 HBA1
29 hemangioma of liver 10.1 CD34 HBA1
30 spleen cancer 10.1 CD34 HBA1
31 conventional angiosarcoma 10.1 CD34 HBA1
32 venous hemangioma 10.1 CD34 HBA1
33 testicular infarct 10.1 AFP FUT4
34 mixed liposarcoma 10.1 CD34 HBA1
35 erythema elevatum diutinum 10.1 CD34 HBA1
36 breast angiosarcoma 10.1 CD34 HBA1
37 senile angioma 10.1 CD34 HBA1
38 interstitial emphysema 10.1 CD34 HBA1
39 spindle cell liposarcoma 10.1 CD34 HBA1
40 cloacogenic carcinoma 10.1 HBA1 PTHLH
41 granulomatous gastritis 10.1 FUT4 NOTCH1
42 alveoli adenoma 10.1 CD34 HBA1
43 mesenchymal cell neoplasm 10.0 CD34 HBA1
44 mixed germ cell cancer 10.0 AFP FUT4
45 infiltrating lipoma 10.0 CD34 HBA1
46 type 1 diabetes mellitus 11 10.0 CTLA4 HBA1 NOTCH1
47 congestive heart failure 10.0
48 thrombosis 10.0
49 placental abruption 10.0
50 diffuse neonatal hemangiomatosis 10.0

Graphical network of the top 20 diseases related to Chorioangioma:



Diseases related to Chorioangioma

Symptoms & Phenotypes for Chorioangioma

GenomeRNAi Phenotypes related to Chorioangioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased human papilloma virus 16 (HPV16) pseudovirus infection GR00306-A 9.35 APPL1 CRELD1 CTLA4 PIK3CG PTHLH
2 Decreased telomerase activity GR00156-A 8.8 APPL1 FGFR3 MAPK14

MGI Mouse Phenotypes related to Chorioangioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.11 APPL1 CRELD1 CTLA4 FUT4 MAPK14 NOTCH1
2 cellular MP:0005384 10.09 APPL1 CD34 CRELD1 FGFR3 FUT4 MAPK14
3 hematopoietic system MP:0005397 10.07 APPL1 CD34 CTLA4 FGFR3 FUT4 IL24
4 homeostasis/metabolism MP:0005376 10.06 AFP APPL1 CD34 CTLA4 FGFR3 IL24
5 endocrine/exocrine gland MP:0005379 9.95 AFP CTLA4 MAPK14 NOTCH1 OXT PIK3CG
6 immune system MP:0005387 9.91 APPL1 CD34 CTLA4 FGFR3 FUT4 MAPK14
7 integument MP:0010771 9.76 CD34 CTLA4 FGFR3 MAPK14 NOTCH1 OXT
8 mortality/aging MP:0010768 9.65 AFP APPL1 CRELD1 CTLA4 FGFR3 MAPK14
9 neoplasm MP:0002006 9.1 AFP CD34 FGFR3 MAPK14 NOTCH1 PTHLH

Drugs & Therapeutics for Chorioangioma

Search Clinical Trials , NIH Clinical Center for Chorioangioma

Genetic Tests for Chorioangioma

Anatomical Context for Chorioangioma

MalaCards organs/tissues related to Chorioangioma:

41
Placenta, Heart, Liver, Skin, Ovary, Spleen, Thyroid

Publications for Chorioangioma

Articles related to Chorioangioma:

(show top 50) (show all 177)
# Title Authors Year
1
Placental abruption after amnioreduction for polyhydramnios caused by chorioangioma. ( 29507014 )
2018
2
Coexistence of Kasabach-Merritt Syndrome and placental chorioangioma in a premature infant. ( 29991142 )
2018
3
Placental Chorioangioma with Nonimmune Hydrops Fetalis. ( 30075468 )
2018
4
Pregnancy complications and adverse outcomes in placental chorioangioma: a retrospective cohort analysis. ( 30431372 )
2018
5
Chorioangioma of Placenta. ( 29453483 )
2017
6
Giant chorioangioma treated with interstitial laser. ( 29072331 )
2017
7
A case of twin reversed arterial perfusion (TRAP) sequence misdiagnosed as a chorioangioma. ( 28287285 )
2017
8
Call for Caution: Neonatal Portal Vein Thrombosis following Enbucrilate Embolization of Placental Chorioangioma. ( 28796996 )
2017
9
Chorioangioma of Placenta: A Rare Case of Near-Miss Mortality. ( 28546672 )
2017
10
Ultrasound-Guided Percutaneous Embolisation of Placental Chorioangioma Using Cyanoacrylate. ( 26727372 )
2017
11
Unusual complications of placental chorioangioma: consumption coagulopathy and hypertension in a preterm newborn. ( 27154993 )
2016
12
EP21.20: Prenatal diagnosis and management of anemia in a large placental chorioangioma. ( 27644220 )
2016
13
Chorioamniotic membrane separation caused by the seromucinous collection from a placental chorioangioma. ( 27200315 )
2016
14
Propranolol during pregnancy for large chorioangioma. ( 26160051 )
2015
15
Giant placental chorioangioma with favorable outcome: a case report and literature review of literature. ( 25944604 )
2015
16
Placental tumor (chorioangioma) as a cause of polyhydramnios: a case report. ( 25429242 )
2014
17
Natural history and pregnancy outcome in patients with placental chorioangioma. ( 24132889 )
2014
18
Giant Chorioangioma Treated In Utero via Laser of Feeding Vessels with Subsequent Development of Multifocal Infantile Hemangiomas. ( 24941233 )
2014
19
A rare giant placental chorioangioma with favorable outcome: A case report and review of the literature. ( 25043806 )
2014
20
Placental chorioangioma: literature review. ( 24334427 )
2014
21
Placenta chorioangioma: a rare case and systematic review of literature. ( 24460422 )
2014
22
Placental chorioangioma. ( 24612886 )
2014
23
Normal evolution of pregnancy complicated by a giant placental chorioangioma. ( 25134303 )
2014
24
Color Doppler score: a new approach for monitoring a large placental chorioangioma. ( 25295202 )
2014
25
Rapid evolution of placental chorioangioma: natural progression and outcome. ( 23443197 )
2013
26
Chorioangioma: an uncommon cause of hydramnios and consequent preterm labor in second trimester of pregnancy. ( 23767383 )
2013
27
Prenatal three dimensional ultrasonography and expectant management of placental chorioangioma: a case report. ( 23691706 )
2013
28
Prenatal diagnosis and fetomaternal outcomes of two cases with placental chorioangioma. ( 24251055 )
2013
29
Giant placental chorioangioma with intrauterine fetal death. ( 24362665 )
2013
30
Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia: a rare placental abnormality. ( 23840989 )
2013
31
Fetomaternal hemorrhage with intraplacental chorioangioma. ( 22925543 )
2013
32
High-output cardiac failure in a fetus with thanatophoric dysplasia associated with large placental chorioangioma: case report. ( 22508320 )
2012
33
Fetoscopic laser photocoagulation of feeding vessels to a large placental chorioangioma following fetal deterioration after amnioreduction. ( 22086270 )
2012
34
Masked anemia due to cardiac tamponade in a hydropic fetus caused by placental chorioangioma. ( 21953918 )
2012
35
Combined approach in a large placental chorioangioma case with intratumoral alcohol injection, cordocentesis, IU transfusion, and amnioreduction. ( 22432544 )
2012
36
Antenatal embolization of a large placental chorioangioma: a case report. ( 22759589 )
2012
37
Chorioangioma of placenta: a rare placental cause for adverse fetal outcome. ( 22754703 )
2012
38
Prenatal management and perinatal outcome in giant placental chorioangioma complicated with hydrops fetalis, fetal anemia and maternal mirror syndrome. ( 22840187 )
2012
39
Placental chorioangioma - an unusual cause of acute polyhydramnios with an isolated rise in maternal serum ALT: a clinical marker of disease and/or risk? ( 21973147 )
2011
40
Pregnancy outcomes and ultrasonographic diagnosis in patients with histologically-proven placental chorioangioma. ( 21745690 )
2011
41
Giant placental chorioangioma: a rare cause of fetal hydrops. ( 22696752 )
2011
42
Placental chorioangioma as the cause of non-immunologic hydrops fetalis; a case report. ( 23056775 )
2011
43
Giant placental chorioangioma: natural history and pregnancy outcome. ( 19859897 )
2010
44
Antenatal embolization of a large chorioangioma by percutaneous Glubran 2 injection. ( 20737457 )
2010
45
Placental chorioangioma and chorioangiosis. clinicopathological study of six unusual vascular lesions of the placenta--case reports. ( 20101866 )
2009
46
Chorioangioma of the placenta with hydrops foetalis. ( 19534382 )
2009
47
Hydrops fetalis associated with chorioangioma and thrombosis of umbilical vein. ( 20112613 )
2009
48
Endoscopic laser coagulation following amnioreduction for the management of a large placental chorioangioma. ( 19918962 )
2009
49
Placental mass - clinically suspected chorioangioma. ( 28191070 )
2009
50
A large chorioangioma causing intrauterine foetal demise. ( 19757713 )
2009

Variations for Chorioangioma

Expression for Chorioangioma

Search GEO for disease gene expression data for Chorioangioma.

Pathways for Chorioangioma

GO Terms for Chorioangioma

Cellular components related to Chorioangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 AFP CD34 FGFR3 HBA1 IL24 MAPK14
2 cell periphery GO:0071944 9.13 CD34 FUT4 NOTCH1

Biological processes related to Chorioangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endocardial cushion development GO:0003197 8.96 CRELD1 NOTCH1
2 response to muramyl dipeptide GO:0032495 8.62 MAPK14 NOTCH1

Sources for Chorioangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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