MCID: CHR074
MIFTS: 47

Choriocarcinoma

Categories: Rare diseases, Cancer diseases, Reproductive diseases, Fetal diseases

Aliases & Classifications for Choriocarcinoma

MalaCards integrated aliases for Choriocarcinoma:

Name: Choriocarcinoma 12 76 53 37 55 44 15 73
Chorioepithelioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3594
ICD10 33 C58
MeSH 44 D002822
NCIt 50 C2948
KEGG 37 H00028
UMLS 73 C0008497

Summaries for Choriocarcinoma

MalaCards based summary : Choriocarcinoma, also known as chorioepithelioma, is related to gestational choriocarcinoma and choriocarcinoma of ovary. An important gene associated with Choriocarcinoma is H19 (H19, Imprinted Maternally Expressed Transcript
Control of imprinting. Containing miRNA miR-675.
Dysfunction Pattern: Expression [differentially expressed]), and among its related pathways/superpathways are Glucose / Energy Metabolism and Regulation of IFNA signaling. The drugs Bleomycin and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include placenta, ovary and lung.

Wikipedia : 76 Choriocarcinoma is a malignant, trophoblasticcancer, usually of the placenta. It is characterized by... more...

Related Diseases for Choriocarcinoma

Diseases related to Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 172)
# Related Disease Score Top Affiliating Genes
1 gestational choriocarcinoma 34.4 ABCG2 CSH1 H19
2 choriocarcinoma of ovary 33.8 CSH1 CSH2
3 choriocarcinoma of the testis 33.7 CSH1 CSH2 HLA-G
4 non-gestational choriocarcinoma 33.4 CSH1 CSH2
5 hydatidiform mole, recurrent, 1 32.9 CGA CGB3 H19
6 mixed germ cell tumor 31.4 CGA CGB3
7 ectopic pregnancy 31.2 CGA CGB3 CGB7
8 epithelioid trophoblastic tumor 31.0 CGB3 CSH1
9 gestational trophoblastic neoplasm 31.0 CSH1 CSH2 H19
10 testicular seminoma 30.6 CGA CGB3
11 trophoblastic neoplasm 30.5 CGA CSH1 H19 LNPEP
12 seminoma 30.3 CGA CGB3 CGB7
13 placenta disease 30.2 CGB3 CSH1 CSH2
14 placental site trophoblastic tumor 30.1 CGB3 CSH1 GPC3 LNPEP
15 adrenocortical carcinoma, hereditary 29.9 CYP11A1 CYP19A1 H19
16 pre-eclampsia 28.9 H19 HLA-G LNPEP MALAT1
17 placental choriocarcinoma 12.1
18 fallopian tube gestational choriocarcinoma 12.0
19 pineal region choriocarcinoma 12.0
20 non-gestational ovarian choriocarcinoma 12.0
21 gestational ovarian choriocarcinoma 12.0
22 primary non-gestational choriocarcinoma of ovary 12.0
23 childhood choriocarcinoma of the testis 11.9
24 adult central nervous system choriocarcinoma 11.9
25 pediatric cns choriocarcinoma 11.9
26 pulmonary artery choriocarcinoma 11.8
27 testicular monophasic choriocarcinoma 11.8
28 gestational uterine corpus choriocarcinoma 11.8
29 uterine corpus choriocarcinoma 11.8
30 childhood choriocarcinoma of the ovary 11.8
31 choriocarcinoma of the central nervous system 11.8
32 gestational trophoblastic tumor 11.5
33 testicular germ cell tumor 11.3
34 teratocarcinoma 10.9
35 sacrococcygeal teratoma 10.8 CGA CGB7
36 triploidy 10.8 CGA CGB7
37 oocyte maturation defect 1 10.8 CGA CYP19A1
38 luteoma 10.7 CGA CYP19A1
39 testicular trophoblastic tumor 10.6 CSH1 CSH2
40 uterine anomalies 10.4 CSH1 CSH2 CYP19A1
41 ovarian disease 10.4 CGA CYP11A1 CYP19A1
42 female reproductive system disease 10.4 CSH1 CSH2 CYP19A1
43 testicular granulosa cell tumor 10.3 CSH1 CSH2
44 juvenile type testicular granulosa cell tumor 10.3 CSH1 CSH2
45 invasive mole 10.3
46 testicular leydig cell tumor 10.3 CGB3 CYP11A1
47 germ cells tumors 10.2
48 adenocarcinoma 10.2
49 prostate disease 10.2 H19 MALAT1
50 hepatitis 10.1

Graphical network of the top 20 diseases related to Choriocarcinoma:



Diseases related to Choriocarcinoma

Symptoms & Phenotypes for Choriocarcinoma

Drugs & Therapeutics for Choriocarcinoma

Drugs for Choriocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 153)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bleomycin Approved, Investigational Phase 2, Phase 3,Phase 3 11056-06-7 5360373
2
Cisplatin Approved Phase 2, Phase 3,Phase 3,Phase 1 15663-27-1 84093 441203 2767
3
Etoposide Approved Phase 2, Phase 3,Phase 3,Phase 1 33419-42-0 36462
4
Lenograstim Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1 135968-09-1
5
Paclitaxel Approved, Vet_approved Phase 2, Phase 3,Phase 3,Phase 1 33069-62-4 36314
6
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
7
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
8
Oxaliplatin Approved, Investigational Phase 3,Phase 1 61825-94-3 5310940 9887054 43805 6857599
9
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
10
Mesna Approved, Investigational Phase 3,Phase 1,Phase 2 3375-50-6 598
11
Dactinomycin Approved, Investigational Phase 3 50-76-0 2019 457193
12
Methotrexate Approved Phase 3,Phase 2 1959-05-2, 59-05-2 126941
13
Captopril Approved Phase 3 62571-86-2 44093
14
Cyclophosphamide Approved, Investigational Phase 3,Phase 1 50-18-0, 6055-19-2 2907
15
Palivizumab Approved, Investigational Phase 3 188039-54-5
16
Ribavirin Approved Phase 3 36791-04-5 37542
17
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
18
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
19
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
20
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
21
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
22
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
23
Levoleucovorin Approved, Investigational Phase 3,Phase 2,Phase 1 68538-85-2
24
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
25
Promethazine Approved, Investigational Phase 3 60-87-7 4927
26
Vinblastine Approved Phase 3 865-21-4 13342 241903
27
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
28
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Phase 1 58-05-9 143 6006
29 Albumin-Bound Paclitaxel Phase 2, Phase 3,Phase 3,Phase 1
30 Anti-Bacterial Agents Phase 2, Phase 3,Phase 3,Phase 1
31 Antibiotics, Antitubercular Phase 2, Phase 3,Phase 3
32 Antimitotic Agents Phase 2, Phase 3,Phase 3,Phase 1
33 Antineoplastic Agents, Phytogenic Phase 2, Phase 3,Phase 3,Phase 1
34 Etoposide phosphate Phase 2, Phase 3,Phase 3,Phase 1
35 Topoisomerase Inhibitors Phase 2, Phase 3,Phase 3,Phase 1
36 Alkylating Agents Phase 3,Phase 1,Phase 2
37 Antineoplastic Agents, Alkylating Phase 3,Phase 1,Phase 2
38
Isophosphamide mustard Phase 3,Phase 1,Phase 2 0
39 Anti-Infective Agents Phase 3,Phase 1,Phase 2
40 Antimetabolites Phase 3,Phase 2,Phase 1
41 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
42 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
43 Antiviral Agents Phase 3,Phase 1,Phase 2
44 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
45 BB 1101 Phase 3,Phase 1,Phase 2
46 Dexamethasone acetate Phase 3,Phase 1,Phase 2 1177-87-3
47 Antirheumatic Agents Phase 3,Phase 2,Phase 1
48 Dermatologic Agents Phase 3,Phase 2
49 Folic Acid Antagonists Phase 3,Phase 2
50 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 69)
# Name Status NCT ID Phase Drugs
1 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
2 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
3 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed NCT00003702 Phase 3 Methotrexate
4 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Completed NCT00053352 Phase 3 cisplatin;etoposide
5 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
6 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
7 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
8 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
9 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
10 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
11 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
12 Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain Completed NCT00293358 Phase 3 carboplatin;cisplatin;etoposide phosphate;ifosfamide
13 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide
14 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
15 Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01535053 Phase 3 Leucovorin Calcium;Methotrexate
16 Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia Not yet recruiting NCT03280979 Phase 2, Phase 3 rescue regimen;high dose methotrxate
17 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
18 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
19 Single Patient Treatment Protocol of TRC105 Combined With Standard-dose Bevacizumab for a Single Patient With Metastatic And Refractory Choriocarcinoma Completed NCT02396511 Phase 2
20 A Trial for Patients With Gestational Trophoblastic Disease Completed NCT00190918 Phase 2 Pemetrexed
21 Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Completed NCT00467051 Phase 2 paclitaxel;carboplatin;ifosfamide
22 Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Completed NCT00521118 Phase 2
23 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
24 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
25 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
26 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
27 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
28 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
29 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
30 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
31 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
32 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
33 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
34 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2 cisplatin;ifosfamide;paclitaxel
35 Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors Completed NCT00047320 Phase 2 carboplatin;etoposide;ifosfamide;thiotepa
36 Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors Completed NCT00002472 Phase 2 cisplatin;etoposide
37 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
38 Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) Recruiting NCT02664961 Phase 2 TRC105;Bevacizumab
39 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
40 Role of Axumin PET Scan in Germ Cell Tumor Recruiting NCT03426865 Phase 2 Axumin PET scan
41 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
42 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
43 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
44 Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1 oxaliplatin;fluorouracil;leucovorin calcium
45 Sunitinib in Treating Young Patients With Refractory Solid Tumors Completed NCT00387920 Phase 1 sunitinib malate
46 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1 pazopanib hydrochloride
47 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
48 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1 vorinostat;bortezomib
49 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
50 Safety and Tolerability Study of AZD2171 in Combination With AZD0530 in Patients With Advanced Solid Tumours Completed NCT00475956 Phase 1 AZD2171;AZD0530

Search NIH Clinical Center for Choriocarcinoma

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: choriocarcinoma

Genetic Tests for Choriocarcinoma

Anatomical Context for Choriocarcinoma

MalaCards organs/tissues related to Choriocarcinoma:

41
Placenta, Ovary, Lung, Brain, Testis, Bone, Bone Marrow

Publications for Choriocarcinoma

Articles related to Choriocarcinoma:

(show top 50) (show all 1154)
# Title Authors Year
1
The choriocarcinoma cell line JEG-3 upregulates regulatory T cell phenotypes and modulates pro-inflammatory cytokines through HLA-G. ( 29198970 )
2018
2
The role of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) in modulating immune detection of choriocarcinoma. ( 29324974 )
2018
3
Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis. ( 29197012 )
2018
4
The Clinical Significance of a Small Component of Choriocarcinoma in Testicular Mixed Germ Cell Tumor (MGCT). ( 29794869 )
2018
5
Curcumol Controls Choriocarcinoma Stem-Like Cells Self-Renewal via Repression of DNA Methyltransferase (DNMT)- and Histone Deacetylase (HDAC)-Mediated Epigenetic Regulation. ( 29363667 )
2018
6
Transmission of a <i>TP53</i> germline mutation from unaffected male carrier associated with pediatric glioblastoma in his child and gestational choriocarcinoma in his female partner. ( 29581140 )
2018
7
Choriocarcinoma with multiple lung metastases from complete hydatidiform mole with coexistent fetus during pregnancy. ( 29845692 )
2018
8
Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions. ( 29686836 )
2018
9
Cutaneous Metastasis of Choriocarcinoma in 2 Male Patients: A Rare Presentation of an Aggressive Malignancy That Dermatopathologists Must Recognize. ( 29944473 )
2018
10
Multidisciplinary approach for treatment of primary hepatic choriocarcinoma in adult male patient. ( 29896579 )
2018
11
Targeted delivery of doxorubicin by CSA-binding nanoparticles for choriocarcinoma treatment. ( 29426237 )
2018
12
Recurrent Cerebral Hemorrhage in Normal Pregnancy Secondary to Mycotic Pseudoaneurysms Related to Choriocarcinoma. ( 28987845 )
2018
13
Erratum: Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions. ( 29877515 )
2018
14
Is chemotherapy always necessary for patients with nonmetastatic gestational trophoblastic neoplasia with histopathological diagnosis of choriocarcinoma? ( 29248195 )
2018
15
Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo. ( 29331935 )
2018
16
Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress. ( 29665822 )
2018
17
Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review. ( 29851778 )
2018
18
Daidzein induces choriocarcinoma cell apoptosis in a dose-dependent manner via the mitochondrial apoptotic pathway. ( 29436666 )
2018
19
Durable remission for a woman with refractory choriocarcinoma treated with anti-endoglin monoclonal antibody and bevacizumab: A case from the New England Trophoblastic Disease Center, Brigham and Women's Hospital and Dana-Farber Cancer Institute. ( 29217138 )
2018
20
Testicular choriocarcinoma with cutaneous metastasis in a 19-year-old man. ( 29665032 )
2018
21
Non-Gestational Choriocarcinoma with Widespread Metastases Presenting with Type 1 Respiratory Failure in a 39-Year-Old Female: Case Report and Review of the Literature. ( 29681814 )
2018
22
Debulking Surgery for Pelvic Recurrence After Surgically-treated Tubal Gestational Choriocarcinoma - A Case Report and Literature Review. ( 29277804 )
2018
23
Relative Effects of Age, Race, and Stage on Mortality in Gestational Choriocarcinoma. ( 29232272 )
2018
24
Intraplacental choriocarcinoma coexisting with fetomaternal hemorrhage: Case report, chemotherapy management, and literature review. ( 29620671 )
2018
25
Pulse actinomycin D as first-line treatment of low-risk post-molar non-choriocarcinoma gestational trophoblastic neoplasia. ( 29792175 )
2018
26
Short tandem repeat analysis for confirmation of uterine non-gestational choriocarcinoma in a postmenopausal Taiwanese woman. ( 29465578 )
2018
27
Spontaneous renal hemorrhage secondary to choriocarcinoma in a man with congenital hypospadias and cryptorchidism: a case report and literature review. ( 29739453 )
2018
28
Gestational Tubal Choriocarcinoma Presenting as a Pregnancy of Unknown Location following Ovarian Induction. ( 29854512 )
2018
29
Primary gastric choriocarcinoma. ( 29745105 )
2018
30
Nonmetastatic Excised Gestational Choriocarcinoma: To Treat or Not to Treat. ( 29406249 )
2018
31
Metastatic Nongestational Choriocarcinoma to the Brain: Case Report and Proposed Treatment Recommendations. ( 29678709 )
2018
32
Cancer-Specific Inhibitory Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-I^ Against Choriocarcinoma in Xenografted Metastatic Mouse Models. ( 29202279 )
2018
33
Successful treatment of multisite hemorrhage by several methods in brain metastasis of choriocarcinoma: A case report. ( 29794762 )
2018
34
Gestational choriocarcinoma associated with a germline TP53 mutation. ( 28477316 )
2017
35
Metastatic gestational choriocarcinoma: a masquerader in obstetrics. ( 28550508 )
2017
36
A Rare Case of Gestational Choriocarcinoma Presenting as Cornual Ectopic Pregnancy. ( 29032067 )
2017
37
The STAT3/NFIL3 signaling axis-mediated chemotherapy resistance is reversed by Raddeanin A via inducing apoptosis in choriocarcinoma cells. ( 29215740 )
2017
38
Pitfalls in Diagnosis and Management of Testicular Choriocarcinoma Metastatic to the Brain: Report of 2 Cases and Review of Literature. ( 28712904 )
2017
39
Case Report: Multiple hemorrhagic metastases to the brain from primary lung choriocarcinoma. ( 28794859 )
2017
40
Prognosis of gestational choriocarcinoma diagnosed incidentally during laparoscopy for a presumed cornual pregnancy: a report of five cases. ( 28607811 )
2017
41
Hypoxia-induced and HIF1I+-VEGF-mediated tight junction dysfunction in choriocarcinoma cells: Implications for preeclampsia. ( 29223764 )
2017
42
A Rare Case of Metastatic Choriocarcinoma of Lung Origin. ( 29362683 )
2017
43
Primary Gastric Choriocarcinoma Presenting as a Pregnancy of Unknown Location. ( 28079767 )
2017
44
Choriocarcinoma in Women: Analysis of a Case Series With Genotyping. ( 28877059 )
2017
45
Treatment of Human Placental Choriocarcinoma Cells with Formaldehyde and Benzene Induced Growth and Epithelial Mesenchymal Transition via Induction of an Antioxidant Effect. ( 28758930 )
2017
46
c-Rel Promotes Invasion of Choriocarcinoma Cells via PI3K/AKT Signaling. ( 28259870 )
2017
47
Evaluation of the effects of antiepileptic drugs on folic acid uptake by human placental choriocarcinoma cells. ( 29223574 )
2017
48
miR-21 Is Overexpressed in Hydatidiform Mole Tissues and Promotes Proliferation, Migration, and Invasion in Choriocarcinoma Cells. ( 27922982 )
2017
49
A gestational choriocarcinoma of the ovary diagnosed by DNA polymorphic analysis: a case report and systematic review of the literature. ( 28728581 )
2017
50
Complete Serologic Response to Pembrolizumab in a Woman With Chemoresistant Metastatic Choriocarcinoma. ( 28742453 )
2017

Variations for Choriocarcinoma

Expression for Choriocarcinoma

Search GEO for disease gene expression data for Choriocarcinoma.

Pathways for Choriocarcinoma

GO Terms for Choriocarcinoma

Cellular components related to Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.32 CGA CGB3 CGB7 CSH1 CSH2 GH2
2 endosome lumen GO:0031904 8.96 CSH1 GH2

Biological processes related to Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.62 CGA CGB3 CGB7 LNPEP
2 sterol metabolic process GO:0016125 9.43 CYP11A1 CYP19A1
3 peptide hormone processing GO:0016486 9.4 CGA CGB3
4 female gamete generation GO:0007292 9.37 CGB3 CGB7
5 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.26 CSH1 GH2
6 ovulation GO:0030728 9.16 CGB3 CGB7
7 regulation of signaling receptor activity GO:0010469 9.1 CGA CGB3 CGB7 CSH1 CSH2 GH2
8 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 8.96 HLA-G LNPEP

Molecular functions related to Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.1 CGA CGB3 CGB7 CSH1 CSH2 GH2

Sources for Choriocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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