MCID: CHR074
MIFTS: 50

Choriocarcinoma

Categories: Cancer diseases, Fetal diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Choriocarcinoma

MalaCards integrated aliases for Choriocarcinoma:

Name: Choriocarcinoma 12 77 54 38 56 45 15 17 74
Chorioepithelioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3594
KEGG 38 H00028
MeSH 45 D002822
NCIt 51 C2948
SNOMED-CT 69 44769000
ICD10 34 C58
UMLS 74 C0008497

Summaries for Choriocarcinoma

Disease Ontology : 12 A placenta cancer that has material basis in trophoblastic cells.

MalaCards based summary : Choriocarcinoma, also known as chorioepithelioma, is related to choriocarcinoma of the testis and gestational choriocarcinoma. An important gene associated with Choriocarcinoma is H19 (H19 Imprinted Maternally Expressed Transcript), and among its related pathways/superpathways are Glucose / Energy Metabolism and Metabolism of steroid hormones. The drugs Paclitaxel and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include placenta, lung and ovary.

Wikipedia : 77 Choriocarcinoma is a malignant, trophoblasticcancer, usually of the placenta. It is characterized by... more...

Related Diseases for Choriocarcinoma

Diseases related to Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 choriocarcinoma of the testis 33.9 CSH1 CSH2 HLA-G
2 gestational choriocarcinoma 33.8 ABCG2 CSH1 H19
3 choriocarcinoma of ovary 33.7 CSH1 CSH2
4 non-gestational choriocarcinoma 33.6 CSH1 CSH2
5 hydatidiform mole, recurrent, 1 32.6 CGA CGB3 H19
6 placental site trophoblastic tumor 32.4 CGB3 CSH1 LNPEP
7 gestational trophoblastic neoplasm 31.1 CSH1 CSH2 H19
8 ectopic pregnancy 31.0 CGA CGB3 CGB7
9 mixed germ cell tumor 30.9 CGA CGB3
10 epithelioid trophoblastic tumor 30.7 CGB3 CSH1
11 seminoma 30.2 CGA CGB3 CGB7
12 testicular seminoma 30.1 CGA CGB3
13 adrenocortical carcinoma, hereditary 29.7 CYP11A1 CYP19A1 H19
14 trophoblastic neoplasm 29.7 CGA CSH1 H19 LNPEP
15 pre-eclampsia 29.6 ENPEP H19 HLA-G LNPEP MALAT1
16 placental choriocarcinoma 12.5
17 fallopian tube gestational choriocarcinoma 12.4
18 gestational ovarian choriocarcinoma 12.4
19 childhood choriocarcinoma of the testis 12.3
20 adult central nervous system choriocarcinoma 12.3
21 childhood choriocarcinoma of the ovary 12.3
22 pulmonary artery choriocarcinoma 12.3
23 testicular monophasic choriocarcinoma 12.3
24 gestational uterine corpus choriocarcinoma 12.3
25 uterine corpus choriocarcinoma 12.3
26 pineal region choriocarcinoma 12.2
27 non-gestational ovarian choriocarcinoma 12.2
28 primary non-gestational choriocarcinoma of ovary 12.1
29 pediatric cns choriocarcinoma 12.0
30 choriocarcinoma of the central nervous system 12.0
31 gestational trophoblastic tumor 11.6
32 testicular germ cell tumor 11.4
33 teratocarcinoma 11.0
34 invasive mole 10.4
35 adenocarcinoma 10.4
36 sacrococcygeal teratoma 10.4 CGA CGB7
37 triploidy 10.4 CGA CGB7
38 oocyte maturation defect 1 10.4 CGA CYP19A1
39 germ cells tumors 10.4
40 teratoma 10.3
41 luteoma 10.3 CGA CYP19A1
42 chromosomal triplication 10.3 CGA CGB3
43 testicular trophoblastic tumor 10.3 CSH1 CSH2
44 testicular leydig cell tumor 10.2 CGB3 CYP11A1
45 ovarian epithelial cancer 10.2 H19 MALAT1
46 graves disease 1 10.2
47 embryonal carcinoma 10.2
48 hyperthyroidism 10.2
49 uterine anomalies 10.2 CSH1 CSH2 CYP19A1
50 ulcerative stomatitis 10.2 CGB3 CGB7

Graphical network of the top 20 diseases related to Choriocarcinoma:



Diseases related to Choriocarcinoma

Symptoms & Phenotypes for Choriocarcinoma

Drugs & Therapeutics for Choriocarcinoma

Drugs for Choriocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 165)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2, Phase 3,Phase 3,Phase 1 33069-62-4 36314
2
Lenograstim Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1 135968-09-1
3
Bleomycin Approved, Investigational Phase 2, Phase 3,Phase 3 11056-06-7 5360373
4
Cisplatin Approved Phase 2, Phase 3,Phase 3,Phase 1 15663-27-1 441203 84093 2767
5
Etoposide Approved Phase 2, Phase 3,Phase 3,Phase 1 33419-42-0 36462
6
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
7
Oxaliplatin Approved, Investigational Phase 3,Phase 1 61825-94-3 6857599 5310940 9887054 43805
8
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
9
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
10
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 1177-87-3
11
Mesna Approved, Investigational Phase 3,Phase 1,Phase 2 3375-50-6 598
12
Methotrexate Approved Phase 3,Phase 2 1959-05-2, 59-05-2 126941
13
leucovorin Approved Phase 3,Phase 2,Phase 1 58-05-9 6006 143
14
Dactinomycin Approved, Investigational Phase 3 50-76-0 457193 2019
15
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 6055-19-2, 50-18-0 2907
16
Captopril Approved Phase 3 62571-86-2 44093
17
Palivizumab Approved, Investigational Phase 3 188039-54-5
18
Ribavirin Approved Phase 3 36791-04-5 37542
19
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
20
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
21
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
22
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
23
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 2826718 468682
24
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 38904 10339178 498142
25
Levoleucovorin Approved, Investigational Phase 3,Phase 2,Phase 1 68538-85-2
26
Promethazine Approved, Investigational Phase 3 60-87-7 4927
27
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
28
Vinblastine Approved Phase 3 865-21-4 13342 241903
29
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
30
Calcium Approved, Nutraceutical Phase 3,Phase 1 7440-70-2 271
31 Anti-Bacterial Agents Phase 2, Phase 3,Phase 3,Phase 1
32 Etoposide phosphate Phase 2, Phase 3,Phase 3,Phase 1
33 Topoisomerase Inhibitors Phase 2, Phase 3,Phase 3,Phase 1
34 Albumin-Bound Paclitaxel Phase 2, Phase 3,Phase 3,Phase 1
35 Antibiotics, Antitubercular Phase 2, Phase 3,Phase 3
36 Antimitotic Agents Phase 2, Phase 3,Phase 3,Phase 1
37 Antineoplastic Agents, Phytogenic Phase 2, Phase 3,Phase 3,Phase 1
38 Alkylating Agents Phase 3,Phase 1,Phase 2
39 Antineoplastic Agents, Alkylating Phase 3,Phase 1,Phase 2
40
Isophosphamide mustard Phase 3,Phase 1,Phase 2 0
41 Antimetabolites Phase 3,Phase 2,Phase 1
42 Anti-Infective Agents Phase 3,Phase 1,Phase 2
43 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
44 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
45 Immunologic Factors Phase 3,Phase 2,Phase 1
46 Antiviral Agents Phase 3,Phase 1,Phase 2
47 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
48 BB 1101 Phase 3,Phase 1,Phase 2
49 Vitamin B Complex Phase 3,Phase 2,Phase 1
50 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 69)
# Name Status NCT ID Phase Drugs
1 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
2 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
3 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed NCT00003702 Phase 3 Methotrexate
4 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Completed NCT00053352 Phase 3 cisplatin;etoposide
5 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
6 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
7 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
8 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
9 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
10 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
11 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
12 Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain Completed NCT00293358 Phase 3 carboplatin;cisplatin;etoposide phosphate;ifosfamide
13 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide;Etoposide Phosphate
14 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
15 Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01535053 Phase 3 Leucovorin Calcium;Methotrexate
16 Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia Not yet recruiting NCT03280979 Phase 2, Phase 3 rescue regimen;high dose methotrxate
17 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
18 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
19 Single Patient Treatment Protocol of TRC105 Combined With Standard-dose Bevacizumab for a Single Patient With Metastatic And Refractory Choriocarcinoma Completed NCT02396511 Phase 2
20 A Trial for Patients With Gestational Trophoblastic Disease Completed NCT00190918 Phase 2 Pemetrexed
21 Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Completed NCT00467051 Phase 2 Carboplatin;Ifosfamide;Paclitaxel
22 Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Completed NCT00521118 Phase 2
23 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
24 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
25 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
26 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
27 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
28 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
29 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
30 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
31 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
32 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
33 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
34 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2 cisplatin;ifosfamide;paclitaxel
35 Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors Completed NCT00047320 Phase 2 carboplatin;etoposide;ifosfamide;thiotepa
36 Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors Completed NCT00002472 Phase 2 cisplatin;etoposide
37 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
38 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
39 Role of Axumin PET Scan in Germ Cell Tumor Recruiting NCT03426865 Phase 2 Axumin PET scan
40 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
41 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
42 Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) Terminated NCT02664961 Phase 2 TRC105;Bevacizumab
43 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
44 Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1 oxaliplatin;fluorouracil;leucovorin calcium
45 Sunitinib in Treating Young Patients With Refractory Solid Tumors Completed NCT00387920 Phase 1 sunitinib malate
46 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1 pazopanib hydrochloride
47 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
48 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1 vorinostat;bortezomib
49 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
50 Safety and Tolerability Study of AZD2171 in Combination With AZD0530 in Patients With Advanced Solid Tumours Completed NCT00475956 Phase 1 AZD2171;AZD0530

Search NIH Clinical Center for Choriocarcinoma

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: choriocarcinoma

Genetic Tests for Choriocarcinoma

Anatomical Context for Choriocarcinoma

MalaCards organs/tissues related to Choriocarcinoma:

42
Placenta, Lung, Ovary, Brain, Testis, Bone, Bone Marrow

Publications for Choriocarcinoma

Articles related to Choriocarcinoma:

(show top 50) (show all 2512)
# Title Authors Year
1
Metastatic Choriocarcinoma Masquerading as a Congenital Glabellar Hemangioma. ( 29546798 )
2019
2
Clinical significance of circulating tumor cells in predicting disease progression and chemotherapy resistance in patients with gestational choriocarcinoma. ( 30070688 )
2019
3
Carvacrol induces mitochondria-mediated apoptosis via disruption of calcium homeostasis in human choriocarcinoma cells. ( 30070691 )
2019
4
Cesarean section scar choriocarcinoma, an unusual entity with ultrasound, MRI and pathologic correlation. ( 30312854 )
2019
5
Primary esophageal choriocarcinoma: an unusual cause of myocardial infarction. ( 30342025 )
2019
6
A Transplantable Syngeneic Allograft Mouse Model for Nongestational Choriocarcinoma of the Ovary. ( 30636537 )
2019
7
The role of a semi-automated NanoVelcro system in capturing circulating tumor cells and evaluating their prognostic value for gestational choriocarcinoma. ( 30656300 )
2019
8
Short Tandem Repeats Define A Gestational Origin For Metastatic Choriocarcinoma. ( 30685255 )
2019
9
The BeWo cell line derived from a human placental choriocarcinoma is permissive for respiratory syncytial virus infection. ( 30758769 )
2019
10
Primary non-gestational uterine choriocarcinoma mimicking leiomyoma. ( 30775828 )
2019
11
Acute pulmonary hemorrhage associated with metastatic testicular choriocarcinoma in a 46-year-old incarcerated male. ( 30787584 )
2019
12
A promising therapeutic strategy for metastatic gestational trophoblastic disease: Engineered anticancer gene-expressing stem cells to selectively target choriocarcinoma. ( 30867726 )
2019
13
The choriocarcinoma cell line JEG-3 upregulates regulatory T cell phenotypes and modulates pro-inflammatory cytokines through HLA-G. ( 29198970 )
2018
14
The role of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) in modulating immune detection of choriocarcinoma. ( 29324974 )
2018
15
Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis. ( 29197012 )
2018
16
The Clinical Significance of a Small Component of Choriocarcinoma in Testicular Mixed Germ Cell Tumor (MGCT). ( 29794869 )
2018
17
Curcumol Controls Choriocarcinoma Stem-Like Cells Self-Renewal via Repression of DNA Methyltransferase (DNMT)- and Histone Deacetylase (HDAC)-Mediated Epigenetic Regulation. ( 29363667 )
2018
18
Transmission of a <i>TP53</i> germline mutation from unaffected male carrier associated with pediatric glioblastoma in his child and gestational choriocarcinoma in his female partner. ( 29581140 )
2018
19
Choriocarcinoma with multiple lung metastases from complete hydatidiform mole with coexistent fetus during pregnancy. ( 29845692 )
2018
20
Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions. ( 29686836 )
2018
21
Cutaneous Metastasis of Choriocarcinoma in 2 Male Patients: A Rare Presentation of an Aggressive Malignancy That Dermatopathologists Must Recognize. ( 29944473 )
2018
22
Multidisciplinary approach for treatment of primary hepatic choriocarcinoma in adult male patient. ( 29896579 )
2018
23
Targeted delivery of doxorubicin by CSA-binding nanoparticles for choriocarcinoma treatment. ( 29426237 )
2018
24
Recurrent Cerebral Hemorrhage in Normal Pregnancy Secondary to Mycotic Pseudoaneurysms Related to Choriocarcinoma. ( 28987845 )
2018
25
Erratum: Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions. ( 29877515 )
2018
26
Is chemotherapy always necessary for patients with nonmetastatic gestational trophoblastic neoplasia with histopathological diagnosis of choriocarcinoma? ( 29248195 )
2018
27
Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo. ( 29331935 )
2018
28
Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress. ( 29665822 )
2018
29
Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review. ( 29851778 )
2018
30
Daidzein induces choriocarcinoma cell apoptosis in a dose-dependent manner via the mitochondrial apoptotic pathway. ( 29436666 )
2018
31
Durable remission for a woman with refractory choriocarcinoma treated with anti-endoglin monoclonal antibody and bevacizumab: A case from the New England Trophoblastic Disease Center, Brigham and Women's Hospital and Dana-Farber Cancer Institute. ( 29217138 )
2018
32
Testicular choriocarcinoma with cutaneous metastasis in a 19-year-old man. ( 29665032 )
2018
33
Non-Gestational Choriocarcinoma with Widespread Metastases Presenting with Type 1 Respiratory Failure in a 39-Year-Old Female: Case Report and Review of the Literature. ( 29681814 )
2018
34
Debulking Surgery for Pelvic Recurrence After Surgically-treated Tubal Gestational Choriocarcinoma - A Case Report and Literature Review. ( 29277804 )
2018
35
Relative Effects of Age, Race, and Stage on Mortality in Gestational Choriocarcinoma. ( 29232272 )
2018
36
Intraplacental choriocarcinoma coexisting with fetomaternal hemorrhage: Case report, chemotherapy management, and literature review. ( 29620671 )
2018
37
Pulse actinomycin D as first-line treatment of low-risk post-molar non-choriocarcinoma gestational trophoblastic neoplasia. ( 29792175 )
2018
38
Short tandem repeat analysis for confirmation of uterine non-gestational choriocarcinoma in a postmenopausal Taiwanese woman. ( 29465578 )
2018
39
Spontaneous renal hemorrhage secondary to choriocarcinoma in a man with congenital hypospadias and cryptorchidism: a case report and literature review. ( 29739453 )
2018
40
Gestational Tubal Choriocarcinoma Presenting as a Pregnancy of Unknown Location following Ovarian Induction. ( 29854512 )
2018
41
Primary gastric choriocarcinoma. ( 29745105 )
2018
42
Nonmetastatic Excised Gestational Choriocarcinoma: To Treat or Not to Treat. ( 29406249 )
2018
43
Metastatic Nongestational Choriocarcinoma to the Brain: Case Report and Proposed Treatment Recommendations. ( 29678709 )
2018
44
Cancer-Specific Inhibitory Effects of Genetically Engineered Stem Cells Expressing Cytosine Deaminase and Interferon-I^ Against Choriocarcinoma in Xenografted Metastatic Mouse Models. ( 29202279 )
2018
45
Successful treatment of multisite hemorrhage by several methods in brain metastasis of choriocarcinoma: A case report. ( 29794762 )
2018
46
Acute Pancreatitis Caused by Isolated Pancreatic Metastasis From Uterine Choriocarcinoma. ( 30028356 )
2018
47
Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt Signaling Pathway. ( 28983820 )
2018
48
The long non-coding RNA MALAT1 interacted with miR-218 modulates choriocarcinoma growth by targeting Fbxw8. ( 29096355 )
2018
49
Cigarette smoke extract and isoprene resulted in the induction of apoptosis and autophagy in human placenta choriocarcinoma JEG-3 cells. ( 29135079 )
2018
50
Case of Subarachnoid Hemorrhage from Ruptured Oncotic Fusiform Aneurysms from Choriocarcinoma Metastasis Treated with Aneurysmectomy and Vessel Reconstruction. ( 29454960 )
2018

Variations for Choriocarcinoma

Expression for Choriocarcinoma

Search GEO for disease gene expression data for Choriocarcinoma.

Pathways for Choriocarcinoma

GO Terms for Choriocarcinoma

Cellular components related to Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 CGA CGB3 CGB7 CSH1 CSH2 GH2
2 endosome lumen GO:0031904 8.96 CSH1 GH2

Biological processes related to Choriocarcinoma according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.76 CGB3 CGB7 ENPEP LNPEP
2 regulation of signaling receptor activity GO:0010469 9.73 CGA CGB3 CGB7 CSH1 CSH2 GH2
3 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.65 CSH1 CSH2 GH2
4 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.58 CSH1 CSH2 GH2
5 sterol metabolic process GO:0016125 9.55 CYP11A1 CYP19A1
6 peptide hormone processing GO:0016486 9.54 CGA CGB3
7 response to nutrient levels GO:0031667 9.54 CSH1 CSH2 GH2
8 female gamete generation GO:0007292 9.52 CGB3 CGB7
9 peptide catabolic process GO:0043171 9.51 ENPEP LNPEP
10 positive regulation of JAK-STAT cascade GO:0046427 9.5 CSH1 CSH2 GH2
11 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.49 CSH1 GH2
12 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.43 HLA-G LNPEP
13 animal organ development GO:0048513 9.33 CSH1 CSH2 GH2
14 growth hormone receptor signaling pathway GO:0060396 9.13 CSH1 CSH2 GH2
15 positive regulation of growth GO:0045927 8.8 CSH1 CSH2 GH2

Molecular functions related to Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aminopeptidase activity GO:0004177 9.26 ENPEP LNPEP
2 metalloaminopeptidase activity GO:0070006 9.16 ENPEP LNPEP
3 growth hormone receptor binding GO:0005131 9.13 CSH1 CSH2 GH2
4 hormone activity GO:0005179 9.1 CGA CGB3 CGB7 CSH1 CSH2 GH2

Sources for Choriocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
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52 NDF-RT
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56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
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75 UMLS via Orphanet
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