MCID: CHR077
MIFTS: 28

Chorioretinal Scar

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Chorioretinal Scar

MalaCards integrated aliases for Chorioretinal Scar:

Name: Chorioretinal Scar 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:11086
ICD9CM 34 363.3
SNOMED-CT 67 53854005
ICD10 32 H31.0
UMLS 70 C0008512

Summaries for Chorioretinal Scar

MalaCards based summary : Chorioretinal Scar is related to ischemic neuropathy and retinal telangiectasia. An important gene associated with Chorioretinal Scar is SIGLEC5 (Sialic Acid Binding Ig Like Lectin 5), and among its related pathways/superpathways are Phototransduction and Metabolism of fat-soluble vitamins. Affiliated tissues include eye and retina, and related phenotypes are nervous system and pigmentation

Related Diseases for Chorioretinal Scar

Diseases related to Chorioretinal Scar via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 ischemic neuropathy 10.2 VEGFA MROH8
2 retinal telangiectasia 10.2 VEGFA CRB1
3 posterior scleritis 10.2 VEGFA IMPG2
4 angiodysplasia 10.2 VEGFA SIGLEC5
5 pseudopapilledema 10.2 RDH12 CRB1
6 sapho syndrome 10.2 VEGFA SIGLEC5
7 microphthalmia, isolated 6 10.2 CRB1 BEST1
8 leber congenital amaurosis 7 10.2 RDH12 CRB1
9 patterned macular dystrophy 10.2 VEGFA RHO
10 leber congenital amaurosis 16 10.2 RDH12 CRB1
11 leber congenital amaurosis 8 10.2 RDH12 CRB1
12 optic disk drusen 10.2 RHO CRB1
13 leber congenital amaurosis 6 10.2 RDH12 CRB1
14 cancer-associated retinopathy 10.2 VEGFA RHO
15 fallopian tube disease 10.2 VEGFA SIGLEC5
16 macular dystrophy, vitelliform, 2 10.1 IMPG2 BEST1
17 leber congenital amaurosis 9 10.1 RDH12 CRB1
18 leber congenital amaurosis 10 10.1 RDH12 CRB1
19 interval angle-closure glaucoma 10.1 BEST1 ABCA4
20 choroiditis 10.1 VEGFA ABCA4
21 macular dystrophy, vitelliform, 3 10.1 IMPG2 BEST1
22 nonsyndromic retinitis pigmentosa 10.1 BEST1 ABCA4
23 leber congenital amaurosis 3 10.1 RDH12 CRB1
24 macular degeneration, age-related, 6 10.1 BEST1 ABCA4
25 retinitis pigmentosa 32 10.1 IMPG2 ABCA4
26 macular degeneration, age-related, 4 10.1 BEST1 ABCA4
27 retinoblastoma 10.1
28 macular degeneration, age-related, 2 10.1 IMPG2 ABCA4
29 red-green color blindness 10.0 RHO ABCA4
30 isolated macular dystrophy 10.0 BEST1 ABCA4
31 coats disease 10.0 VEGFA RHO CRB1
32 chorioretinitis 10.0 VEGFA CRB1 ABCA4
33 ichthyosis, congenital, autosomal recessive 11 10.0 VEGFA SIGLEC5
34 retinal drusen 10.0 BEST1 ABCA4
35 vitreous disease 10.0 VEGFA RHO BEST1
36 leber congenital amaurosis 2 10.0 RHO RDH12 CRB1
37 leber congenital amaurosis 1 10.0 RHO RDH12 CRB1
38 pigmented paravenous chorioretinal atrophy 10.0 RDH12 CRB1 ABCA4
39 senior-loken syndrome 1 10.0 RHO RDH12 CRB1
40 night blindness 9.9 RHO CRB1 ABCA4
41 basal laminar drusen 9.9 IMPG2 BEST1 ABCA4
42 vitreoretinochoroidopathy 9.9 IMPG2 BEST1 ABCA4
43 retinal detachment 9.9
44 familial retinoblastoma 9.9
45 intraocular retinoblastoma 9.9
46 yemenite deaf-blind hypopigmentation syndrome 9.9 VEGFA RHO ABCA4
47 occult macular dystrophy 9.9 RHO IMPG2 ABCA4
48 glaucoma, primary open angle 9.9 VEGFA RHO ABCA4
49 doyne honeycomb retinal dystrophy 9.9 BEST1 ABCA4
50 gyrate atrophy of choroid and retina 9.9 RHO BEST1 ABCA4

Graphical network of the top 20 diseases related to Chorioretinal Scar:



Diseases related to Chorioretinal Scar

Symptoms & Phenotypes for Chorioretinal Scar

MGI Mouse Phenotypes related to Chorioretinal Scar:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.81 ABCA4 CRB1 CX3CR1 IMPG2 PDE6A RDH12
2 pigmentation MP:0001186 9.35 ABCA4 BEST1 CRB1 CX3CR1 RHO
3 vision/eye MP:0005391 9.32 ABCA4 BEST1 CRB1 CX3CR1 IMPG2 PDE6A

Drugs & Therapeutics for Chorioretinal Scar

Search Clinical Trials , NIH Clinical Center for Chorioretinal Scar

Genetic Tests for Chorioretinal Scar

Anatomical Context for Chorioretinal Scar

MalaCards organs/tissues related to Chorioretinal Scar:

40
Eye, Retina

Publications for Chorioretinal Scar

Articles related to Chorioretinal Scar:

(show top 50) (show all 115)
# Title Authors PMID Year
1
Ocular Co-infection with Mycobacterium Tuberculosis and Toxoplasma Gondii in an Immunocompetent Patient - A Case Report. 61
33544637 2021
2
PATCHING RETINAL BREAKS WITH HEALAFLOW IN 27-GAUGE VITRECTOMY FOR THE TREATMENT OF RHEGMATOGENOUS RETINAL DETACHMENT. 61
31860522 2020
3
Prevalence, Pattern and Risk Factors of Retinal Diseases Among an Elderly Population in Nepal: The Bhaktapur Retina Study. 61
32801619 2020
4
Morphological characteristics of ocular toxoplasmosis and its regression pattern on swept-source optical coherence tomography angiography: a case report. 61
31488090 2019
5
EVALUATION OF SEGMENTAL RETINAL ARTERITIS WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. 61
31313702 2019
6
Acute subretinal abscess in Staphylococcus aureus septicaemia with endophthalmitis showcased by multimodal retinal imaging and with 2-year follow-up. 61
30567135 2018
7
PRESUMED FOVEAL BACILLARY LAYER DETACHMENT IN A PATIENT WITH TOXOPLASMOSIS CHORIORETINITIS AND PACHYCHOROID DISEASE. 61
30142112 2018
8
Clinical Profile of Patients with Tubercular Subretinal Abscess in a Tertiary Eye Care Center in Southern India. 61
27437721 2018
9
Intravitreal Bevacizumab for Choroidal Neovascular Membrane at the Edge of a Healed Choroidal Tuberculoma. 61
27541084 2018
10
Treatment Outcomes of Focal Laser Consolidation during Chemoreduction for Group B Retinoblastoma. 61
31047562 2017
11
Iatrogenic subretinal injection of Ozurdex® implant and its effect on macular edema. 61
28757695 2017
12
Optical Coherence Tomography of Retinal Lesions in Infants With Congenital Zika Syndrome. 61
27832267 2016
13
Visual impairment in pseudoxanthoma elasticum: a survey of 53 patients from Turkey. 61
27150937 2016
14
Successful Management of Diffuse Unilateral Subacute Neuroretinitis with Anthelmintics, and Intravitreal Triamcinolone followed by Laser Photocoagulation. 61
27195096 2016
15
Intravitreal bevacizumab for treatment of choroidal neovascularization secondary to toxoplasmic retinochoroiditis: a case series. 61
24175641 2015
16
Characteristic of low vision patients attending an eye hospital in eastern region of Nepal. 61
26695603 2015
17
Spectral domain optical coherence tomography imaging of punctate outer retinal toxoplasmosis. 61
24843310 2014
18
Successful medical treatment for globe penetration following tooth extraction in a dog. 61
23869648 2014
19
Rhegmatogenous retinal detachment: a reappraisal of its pathophysiology and treatment. 61
24158005 2014
20
Complimentary imaging technologies in blunt ocular trauma. 61
24082670 2013
21
Fuchs' heterochromic cyclitis: a post-infectious manifestation of ocular toxoplasmosis? 61
23070707 2013
22
The absence of vitreous inflammation: one more challenge in diagnosing toxoplasma papillitis. 61
23576658 2013
23
Value of herpes simplex virus type-specific serology: a case report. 61
22465341 2012
24
Photodynamic therapy for symptomatic subretinal fluid related to choroidal nevus. 61
22366902 2012
25
Treatment of dematiaceous fungal keratitis in a dog. 61
22515632 2012
26
A survey of the management of globe perforation during strabismus surgery in the United Kingdom. 61
21635169 2011
27
Review for disease of the year: differential diagnosis of ocular toxoplasmosis. 61
21595533 2011
28
Clinicopathologic findings in Best vitelliform macular dystrophy. 61
21136072 2011
29
Primary transpupillary thermotherapy of choroidal melanocytic lesions. 61
21731333 2011
30
Visual outcome of uveitic cataract in Ibadan. 61
21735999 2010
31
[Toxoplasmic central chorioretinitis]. 61
20827914 2010
32
Effect of ocular contusion in a patient with chronic central serous chorioretinopathy. 61
25390120 2010
33
[Retinal tears in toxoplasmic retinochoroiditis: case series]. 61
20098909 2009
34
Multiple wedge-shaped retinal nerve fiber layer defects in a patient with optic nerve glioma in the contralateral eye: case report. 61
19820802 2009
35
Unilateral laryngeal paralysis in a newborn with congenital varicella syndrome. 61
19054581 2009
36
Diagnosis of ocular toxocariasis by establishing intraocular antibody production. 61
18061138 2008
37
Persistent placoid maculopathy: a new clinical entity. 61
17678692 2007
38
Management of bilateral uveitis in a Toxoplasma gondii-seropositive cat with histopathologic evidence of fungal panuveitis. 61
17565553 2007
39
Ophthalmologic findings in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: a cross-sectional study. 61
16877080 2006
40
Severe ischemic maculopathy in a patient with West Nile virus infection. 61
16749263 2006
41
Atrophic chorioretinal scar and focal scleral bowing following thermochemotherapy with a diode laser for retinoblastoma. 61
16543200 2006
42
A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide. 61
16168412 2006
43
Persistent placoid maculopathy: a new clinical entity. 61
17471331 2006
44
Treatment of retinal breaks with large-spot diode laser photocoagulation. 61
16355959 2005
45
Eye findings in patients with juvenile dermatomyositis. 61
16206356 2005
46
Photodynamic therapy-treated choroidal neovascular membrane secondary to toxoplasmic retinochoroiditis. 61
15064953 2004
47
Severe pigment epithelial alterations in the treatment area following photodynamic therapy for classic choroidal neovascularization in young females. 61
15531316 2004
48
Photodynamic therapy with verteporfin for subfoveal choroidal neovascularization secondary to toxoplasmic chorioretinal scar. 61
15162283 2004
49
Chorioretinal scar growth after 810-nanometer laser treatment for retinoblastoma. 61
15121379 2004
50
Scleral perforations in strabismus surgery: incidence and role of prophylactic cryotherapy--a clinical and experimental study. 61
15255365 2004

Variations for Chorioretinal Scar

Expression for Chorioretinal Scar

Search GEO for disease gene expression data for Chorioretinal Scar.

Pathways for Chorioretinal Scar

GO Terms for Chorioretinal Scar

Cellular components related to Chorioretinal Scar according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 photoreceptor outer segment GO:0001750 9.43 RHO CRB1 ABCA4
2 photoreceptor inner segment GO:0001917 9.33 RHO RDH12 CRB1
3 photoreceptor outer segment membrane GO:0042622 9.32 RHO PDE6A
4 photoreceptor inner segment membrane GO:0060342 8.96 RHO RDH12
5 photoreceptor disc membrane GO:0097381 8.8 RHO PDE6A ABCA4

Biological processes related to Chorioretinal Scar according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 response to stimulus GO:0050896 9.65 RHO RDH12 PDE6A BEST1 ABCA4
2 regulation of rhodopsin mediated signaling pathway GO:0022400 9.51 RHO PDE6A
3 retina development in camera-type eye GO:0060041 9.5 RHO PDE6A CRB1
4 positive regulation of neuroblast proliferation GO:0002052 9.49 VEGFA CX3CR1
5 detection of light stimulus involved in visual perception GO:0050908 9.48 CRB1 BEST1
6 eye photoreceptor cell development GO:0042462 9.46 VEGFA CRB1
7 cellular response to light stimulus GO:0071482 9.43 RHO CRB1
8 rhodopsin mediated signaling pathway GO:0016056 9.4 RHO PDE6A
9 phototransduction, visible light GO:0007603 9.37 RHO ABCA4
10 retinoid metabolic process GO:0001523 9.33 RHO RDH12 ABCA4
11 photoreceptor cell maintenance GO:0045494 9.26 RHO RDH12 CRB1 ABCA4
12 visual perception GO:0007601 9.17 RHO RDH12 PDE6A IMPG2 CRB1 BEST1

Sources for Chorioretinal Scar

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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