MCID: CHR078
MIFTS: 40

Chorioretinitis

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Chorioretinitis

MalaCards integrated aliases for Chorioretinitis:

Name: Chorioretinitis 12 76 53 55 44 15 73
Retinochoroiditis 12

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:8886
ICD10 33 H30 H30.9
ICD9CM 35 363.20
MeSH 44 D002825
NCIt 50 C110923
SNOMED-CT 68 46627006
UMLS 73 C0008513

Summaries for Chorioretinitis

MalaCards based summary : Chorioretinitis, also known as retinochoroiditis, is related to uveitis and endophthalmitis, and has symptoms including eye manifestations An important gene associated with Chorioretinitis is RBP3 (Retinol Binding Protein 3), and among its related pathways/superpathways is Neuroscience. The drugs Prednisolone phosphate and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and testes.

Wikipedia : 76 Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina... more...

Related Diseases for Chorioretinitis

Diseases related to Chorioretinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 262)
# Related Disease Score Top Affiliating Genes
1 uveitis 30.6 RBP3 SAG
2 endophthalmitis 30.2 MRAP OPTN
3 panuveitis 30.1 MRAP RBP3 SAG
4 posterior uveitis 29.9 RBP3 SAG
5 optic papillitis 29.8 EXTL3 MRAP
6 eales disease 29.7 RBP3 SAG
7 autoimmune uveitis 29.6 RBP3 SAG
8 retinochoroidal coloboma 12.5
9 sveinsson chorioretinal atrophy 12.5
10 pigmented paravenous chorioretinal atrophy 12.5
11 microcornea, myopic chorioretinal atrophy, and telecanthus 12.5
12 chorioretinal atrophy, progressive bifocal 12.5
13 focal chorioretinitis 12.3
14 chorioretinal scar 12.3
15 aicardi syndrome 12.2
16 disseminated chorioretinitis 12.2
17 boucher-neuhauser syndrome 12.0
18 peripheral focal chorioretinitis 12.0
19 cleft lower lip cleft lateral canthi chorioretinal 12.0
20 ataxia - hypogonadism - choroidal dystrophy 11.9
21 birdshot chorioretinopathy 11.8
22 gyrate atrophy of choroid and retina 11.5
23 choroiditis 11.5
24 microcephaly and chorioretinopathy, autosomal recessive, 1 11.4
25 congenital toxoplasmosis 11.4
26 microcephaly with or without chorioretinopathy, lymphedema, or mental retardation 11.4
27 choroideremia 11.4
28 wagner vitreoretinopathy 11.2
29 vitreoretinochoroidopathy 11.2
30 oliver-mcfarlane syndrome 11.2
31 late-onset retinal degeneration 11.2
32 arima syndrome 11.1
33 joubert syndrome with oculorenal anomalies 11.1
34 noble bass sherman syndrome 11.1
35 cone-rod dystrophy 2 11.1
36 aicardi-goutieres syndrome 1 11.1
37 microcephaly and chorioretinopathy, autosomal recessive, 3 11.1
38 peripapillary atrophy, beta type 11.0
39 maumenee syndrome 11.0
40 stickler syndrome, type i 10.9
41 optic disc anomalies with retinal and/or macular dystrophy 10.9
42 hypomagnesemia 5, renal, with or without ocular involvement 10.9
43 linear skin defects with multiple congenital anomalies 1 10.9
44 stickler syndrome, type ii 10.9
45 stickler syndrome, type iv 10.9
46 retinal dystrophy with or without extraocular anomalies 10.9
47 microcephaly and chorioretinopathy 3 10.9
48 microcornea posterior megalolenticonus persistent fetal vasculature coloboma 10.9
49 oguchi disease 10.9
50 trichomegaly with intellectual disability, dwarfism and pigmentary degeneration of retina 10.9

Graphical network of the top 20 diseases related to Chorioretinitis:



Diseases related to Chorioretinitis

Symptoms & Phenotypes for Chorioretinitis

UMLS symptoms related to Chorioretinitis:


eye manifestations

Drugs & Therapeutics for Chorioretinitis

Drugs for Chorioretinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 68)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
2
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
3
leucovorin Approved Phase 3 58-05-9 6006 143
4
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
5
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
6
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
7
Sulfadiazine Approved, Investigational, Vet_approved Phase 3 68-35-9 5215
8
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
9
Pyrimethamine Approved, Investigational, Vet_approved Phase 3 58-14-0 4993
10
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
11
Trimethoprim Approved, Vet_approved Phase 3 738-70-5 5578
12
Sulfamethoxazole Approved Phase 3 723-46-6 5329
13
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
14
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7
15 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 1,Phase 2
16 Anti-Bacterial Agents Phase 3
17
protease inhibitors Phase 3
18 Hormones Phase 3,Phase 1,Phase 2
19 Antiprotozoal Agents Phase 3
20 Antineoplastic Agents, Hormonal Phase 3,Phase 2
21 Peripheral Nervous System Agents Phase 3
22 Antiparasitic Agents Phase 3
23 Folic Acid Antagonists Phase 3
24 Antiemetics Phase 3
25 Vitamin B Complex Phase 3
26 Clindamycin palmitate Phase 3
27 Anti-Inflammatory Agents Phase 3,Phase 2,Not Applicable
28 HIV Protease Inhibitors Phase 3
29 glucocorticoids Phase 3,Phase 2
30 Folate Phase 3
31 Antimalarials Phase 3
32 Anti-Infective Agents Phase 3,Phase 2
33 Gastrointestinal Agents Phase 3
34 Prednisolone acetate Phase 3
35 Hormone Antagonists Phase 3,Phase 1,Phase 2
36 BB 1101 Phase 3
37 Clindamycin phosphate Phase 3
38 Neuroprotective Agents Phase 3
39 Autonomic Agents Phase 3
40 Protective Agents Phase 3
41 Vitamin B9 Phase 3
42 Methylprednisolone acetate Phase 3
43 Cytochrome P-450 Enzyme Inhibitors Phase 3
44 Renal Agents Phase 3
45 Trimethoprim, Sulfamethoxazole Drug Combination Phase 3
46 Anti-Infective Agents, Urinary Phase 3
47 Immunoglobulin G Phase 3
48 Antibodies Phase 3
49 Immunoglobulins, Intravenous Phase 3
50 gamma-Globulins Phase 3

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis Unknown status NCT00372294 Phase 3 pyrimethamine-sulfadiazine + prednisolone;Clindamycin+Dexamethasone
2 Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital Toxoplasmosis Unknown status NCT01202500 Phase 3
3 Influence of Trimethoprim-Sulfamethoxazole for the Recurrence of Ocular Toxoplasmosis Completed NCT01449877 Phase 3 Trimethoprim-Sulfamethoxazole
4 A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV) Active, not recruiting NCT01376778 Phase 3 CMV hyperimmune globulin
5 Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis Completed NCT01552044 Phase 1, Phase 2 Spironolactone;Placebo
6 Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a Completed NCT00508040 Phase 2 interferon alpha 2a;prednisone
7 Safety and Efficacy of AIN457 in Noninfectious Uveitis Completed NCT00685399 Phase 2 AIN457;AIN 457;AIN457
8 ACTH as A Re-emerging theRapy for Uveitis (The ACTHAR Study) Recruiting NCT02931175 Phase 2 ACTH gel
9 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438 Not Applicable Anti-toxoplasmosis treatment;Anti-inflammatory treatments
10 Study of the Choroidal Thickness Variations After Ingestion of RedBull® Energy Drink Completed NCT02856256 Not Applicable
11 Relevance of Gastric Aspirate in HCMV Detection Recruiting NCT03262194
12 Lyon Cohort of Maternal and Congenital Toxoplasma Infections Recruiting NCT02936921
13 Genetics of Uveitis Recruiting NCT02357238
14 Ocular Manifestations in Rheumatic Diseases Active, not recruiting NCT03753893
15 Postnatal HCMV Infection in Very Preterm Infants. Implications, Morbidity, Growth and Neurodevelopmental Outcomes. Withdrawn NCT01151462

Search NIH Clinical Center for Chorioretinitis

Cochrane evidence based reviews: chorioretinitis

Genetic Tests for Chorioretinitis

Anatomical Context for Chorioretinitis

MalaCards organs/tissues related to Chorioretinitis:

41
Retina, Eye, Testes, Bone, Skin, Heart, Liver

Publications for Chorioretinitis

Articles related to Chorioretinitis:

(show top 50) (show all 589)
# Title Authors Year
1
Choroidal Thickness in Birdshot Retinochoroiditis Over a 2-Year Period. ( 29920484 )
2019
2
Fungaemia caused by obstructive renal candida bezoars leads to bilateral chorioretinitis: a case report. ( 29548319 )
2018
3
Unilateral macular chorioretinitis in subacute sclerosing panencephalitis studied by spectral domain optical coherence tomography. ( 29942191 )
2018
4
Syphilitic chorioretinitis: Final outcome without treatment. ( 29452719 )
2018
5
NUT carcinoma of the sinonasal tract infiltrating the orbit in a man with birdshot chorioretinitis. ( 29755274 )
2018
6
Chorioretinitis sclopetaria caused by an intraorbital metallic foreign body. ( 29924198 )
2018
7
Varicella zoster virus-associated Chorioretinitis: a case report. ( 29402251 )
2018
8
Stroke Due to Cerebral Vasculitis in a Patient with Relentless Placoid Chorioretinitis. ( 28282738 )
2018
9
Pregnancy-induced hypertension-related chorioretinitis resembling uveal effusion syndrome: A case report. ( 30045283 )
2018
10
PRESUMED FOVEAL BACILLARY LAYER DETACHMENT IN A PATIENT WITH TOXOPLASMOSIS CHORIORETINITIS AND PACHYCHOROID DISEASE. ( 30142112 )
2018
11
Multimodal imaging of multifocal chorioretinitis secondary to endogenous candida infection. ( 30293205 )
2018
12
Menagerie: <em>Bartonella henselae</em> chorioretinitis in the setting of diverse animal exposure. ( 30376658 )
2018
13
A challenging case of chorioretinitis and skin lesions in a lung transplant recipient. ( 30476363 )
2018
14
Comparison of Retinal and Choroidal Involvement in Sarcoidosis-related Chorioretinitis Using Fluorescein and Indocyanine Green Angiography. ( 30479712 )
2018
15
Swept-source optical coherence tomography and optical coherence tomography angiography in acquired toxoplasmic chorioretinitis: a case report. ( 30509327 )
2018
16
Management of giant retinal tear and retinal detachment in a patient with active toxoplasmosis retinochoroiditis. ( 29780938 )
2018
17
Contribution of dual fluorescein and indocyanine green angiography to the appraisal of posterior involvement in birdshot retinochoroiditis and Vogt-Koyanagi-Harada disease. ( 28299496 )
2018
18
Tattoo associated retinochoroiditis. ( 28844569 )
2018
19
Failure of systemic oral doxycycline in preventing ocular toxoplasmic retinochoroiditis in French military personnel. ( 29317472 )
2018
20
PERIVASCULAR THICKENING ON OPTICAL COHERENCE TOMOGRAPHY AS A MARKER OF INFLAMMATION IN BIRDSHOT RETINOCHOROIDITIS. ( 29543632 )
2018
21
Intravitreal Clindamycin and Dexamethasone Combined with Systemic Oral Antitoxoplasma Therapy versus Intravitreal Therapy Alone in the Management of Toxoplasma Retinochoroiditis: A Retrospective Study. ( 29619254 )
2018
22
Toxoplasmic retinochoroiditis caused by Toxoplasma gondii strain ToxoDB#65. ( 29859747 )
2018
23
Immune Mediators against Toxoplasma Gondii during Reactivation of Toxoplasmic Retinochoroiditis. ( 30081671 )
2018
24
Adverse Reactions in Antifolate-Treated Toxoplasmic Retinochoroiditis. ( 30191431 )
2018
25
Eccentric fixation patterns, clinical findings, and reading speed in patients with bilateral toxoplasmic macular retinochoroiditis. ( 30208142 )
2018
26
Low-grade "benign" birdshot retinochoroiditis: prevalence and characteristics. ( 30474776 )
2018
27
Clinical and biological factors associated with recurrences of severe toxoplasmic retinochoroiditis confirmed by aqueous humor analysis. ( 30502335 )
2018
28
Fundus Autofluorescence Findings in Eyes With Birdshot Chorioretinitis. ( 28800648 )
2017
29
Contribution of Dual Fluorescein and Indocyanine Green Angiography to the Appraisal of Presumed Tuberculous Chorioretinitis in a Non-endemic Area. ( 28299004 )
2017
30
Use of Smartphone Funduscopy to aid Diagnosis of chorioretinitis after donor-recipient mismatched cardiac transplantation. ( 28951505 )
2017
31
Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study. ( 28769551 )
2017
32
Toxoplasmosis with chorioretinitis in an HIV-infected child with no visual complaints-importance of fundus examination. ( 28058107 )
2017
33
Rapid resolution of toxoplasma chorioretinitis treatment using quadruple therapy. ( 29238162 )
2017
34
Optical Coherence Tomography Findings in Endogenous Fungal Chorioretinitis, Retinitis, and Endophthalmitis. ( 29121358 )
2017
35
SPONTANEOUS IMPROVEMENT OF SYPHILIS CHORIORETINITIS: CASE REPORT AND REVIEW OF THE LITERATURE. ( 29176535 )
2017
36
Infectious chorioretinitis in an immunocompetent patient: A diagnostic dilemma. ( 29044084 )
2017
37
Fungal chorioretinitis with systemic candidiasis in an infant following treatment with broad spectrum antibiotics: A case report. ( 28672927 )
2017
38
Birdshot Chorioretinitis and Fundus Autofluorescence: Novel Insights Into Disease Pathogenesis. ( 28800649 )
2017
39
A Novel clinical sign in Intraocular Tuberculosis: Active chorioretinitis within chorioretinal atrophy. ( 29152599 )
2017
40
VITREOUS TREPONEMAL ANTIBODY AS A SUPPLEMENTARY TEST TO SEROLOGY FOR THE CONFIRMATION OF SYPHILITIC CHORIORETINITIS. ( 29176538 )
2017
41
Chorioretinitis: a potential clue to the early diagnosis of subacute sclerosing panencephalitis. ( 28512208 )
2017
42
Bevacizumab for treatment of choroidal neovascularization secondary to candida chorioretinitis. ( 28361379 )
2017
43
CLINICAL PATHOLOGIC CORRELATION OF SARCOIDOSIS-ASSOCIATED MULTIFOCAL CHORIORETINITIS IN AN ELDERLY PATIENT. ( 28145942 )
2017
44
MULTIMODAL IMAGING ADDS NEW INSIGHTS INTO ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINITIS. ( 29023263 )
2017
45
Swept-Source Optical Coherence Tomography Angiography in West Nile Virus Chorioretinitis and Associated Occlusive Retinal Vasculitis. ( 28810044 )
2017
46
GOOD VISUAL OUTCOME IN A BILATERAL MULTIFOCAL SYPHILITIC CHORIORETINITIS, DESPITE LATE DIAGNOSIS. ( 28125501 )
2017
47
Erratum: Intravitreal aflibercept for choroidal neovascularization associated with chorioretinitis: a pilot study [Corrigendum]. ( 28894355 )
2017
48
Bilateral Birdshot Retinochoroiditis and Retinal Astrocytoma. ( 28321351 )
2017
49
RELENTLESS PLACOID CHORIORETINITIS: SUCCESSFUL LONG-TERM TREATMENT WITH INTRAVITREAL TRIAMCINOLONE. ( 28198750 )
2017
50
Why birdshot retinochoroiditis should rather be called 'HLA-A29 uveitis'? ( 28314830 )
2017

Variations for Chorioretinitis

Expression for Chorioretinitis

Search GEO for disease gene expression data for Chorioretinitis.

Pathways for Chorioretinitis

Pathways related to Chorioretinitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 OPTN SAG SRCIN1

GO Terms for Chorioretinitis

Cellular components related to Chorioretinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell projection GO:0042995 8.92 AZIN2 CX3CL1 SAG SRCIN1

Biological processes related to Chorioretinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of protein localization to plasma membrane GO:1903077 8.62 MRAP PID1

Sources for Chorioretinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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