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MCID: CHR410
MIFTS: 24

Choroid Cancer

Categories: Cancer diseases, Eye diseases, Neuronal diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Choroid Cancer

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MalaCards integrated aliases for Choroid Cancer:

Name: Choroid Cancer 12 15 17
Malignant Tumor of the Choroid 12
Malignant Tumor of Choroid 12
Neoplasm of Choroid 12
Choroid Neoplasms 44
Choroid Neoplasm 12
Choroidal Tumor 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Eye diseases Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:12759
ICD9CM 35 190.6
MeSH 44 D002830
NCIt 50 C2949 C3566
SNOMED-CT 68 93755007
ICD10 33 C69.3
UMLS 72 C0008523 C0153630
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Summaries for Choroid Cancer

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MalaCards based summary : Choroid Cancer, also known as malignant tumor of the choroid, is related to macular degeneration, age-related, 1 and retinal detachment. An important gene associated with Choroid Cancer is SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E). The drugs Immunoconjugates and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and testes, and related phenotype is cellular.

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Related Diseases for Choroid Cancer

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Diseases related to Choroid Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 macular degeneration, age-related, 1 29.0 KCNMA1 FANCG
2 retinal detachment 10.1
3 melanoma, uveal 10.0
4 scleritis 9.9
5 melanoma 9.9
6 malignant choroid melanoma 9.9
7 choroiditis 9.8
8 posterior scleritis 9.8
9 ocular melanoma 9.8
10 endophthalmitis 9.8
11 vasculitis 9.8
12 skin melanoma 9.8
13 hemangioma 9.8
14 breast cancer 9.7
15 hepatocellular carcinoma 9.7
16 pheochromocytoma 9.7
17 sarcoidosis 1 9.7
18 lung cancer 9.7
19 granulomatosis with polyangiitis 9.7
20 hydrops, lactic acidosis, and sideroblastic anemia 9.7
21 paraganglioma 9.7
22 adrenal gland pheochromocytoma 9.7
23 common cold 9.7
24 retinal vasculitis 9.7
25 papilledema 9.7
26 preretinal fibrosis 9.7
27 capillary hemangioma 9.7
28 pulmonary tuberculosis 9.7
29 adenocarcinoma 9.7
30 neurilemmoma 9.7
31 cataract 9.7
32 iridocyclitis 9.7
33 anterior uveitis 9.7
34 posttransplant acute limbic encephalitis 9.7
35 rare tumor 9.7
36 macular retinal edema 9.6 KCNMA1 FANCG
37 rubeosis iridis 9.5 SNRPE FANCG

Graphical network of the top 20 diseases related to Choroid Cancer:



Diseases related to Choroid Cancer
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Symptoms & Phenotypes for Choroid Cancer

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MGI Mouse Phenotypes related to Choroid Cancer:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 BAP1 ESCO2 FANCG KCNMA1 NF1
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Drugs & Therapeutics for Choroid Cancer

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Drugs for Choroid Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunoconjugates Phase 1
2 Immunologic Factors Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Collaborative Ocular Melanoma Study (COMS) Unknown status NCT00000124 Phase 3
2 A Phase 1, Open-label, Multicenter Study Evaluating the Safety and Tolerability, Biologic Activity, Pharmacodynamics, and Pharmacokinetics of Single and Repeated Escalating Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma Who Are Planned to Undergo Enucleation or Brachytherapy Completed NCT02771340 Phase 1
3 Characterization of Small Choroidal Tumors Using Functional Optical Coherence Tomography Active, not recruiting NCT01955915
4 Validation of a Molecular Test for Predicting Metastasis in Patients With Uveal Melanoma Withdrawn NCT00406120

Search NIH Clinical Center for Choroid Cancer

Cochrane evidence based reviews: choroid neoplasms

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Genetic Tests for Choroid Cancer

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Anatomical Context for Choroid Cancer

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MalaCards organs/tissues related to Choroid Cancer:

41
Eye, Brain, Testes
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Publications for Choroid Cancer

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Articles related to Choroid Cancer:

# Title Authors PMID Year
1
[An analysis of the cause of misdiagnosis with ocular opportunistic infection]. 38
10437001 1997
2
Choroid plexus carcinoma. Case report. 38
8855084 1996
3
[Study of scleral perforations caused by choroid cancer]. 38
13472382 1957
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Variations for Choroid Cancer

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Expression for Choroid Cancer

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Search GEO for disease gene expression data for Choroid Cancer.
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Pathways for Choroid Cancer

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GO Terms for Choroid Cancer

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Biological processes related to Choroid Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 8.62 NF1 KCNMA1
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Sources for Choroid Cancer

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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