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MCID: CHR410
MIFTS: 22

Choroid Cancer

Categories: Cancer diseases, Neuronal diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Choroid Cancer

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MalaCards integrated aliases for Choroid Cancer:

Name: Choroid Cancer 12 15 17
Malignant Tumor of the Choroid 12
Malignant Tumor of Choroid 12
Neoplasm of Choroid 12
Choroid Neoplasms 44
Choroid Neoplasm 12
Choroidal Tumor 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:12759
ICD9CM 34 190.6
MeSH 44 D002830
NCIt 50 C2949 C3566
SNOMED-CT 67 127001008 93755007
ICD10 32 C69.3
UMLS 71 C0008523 C0153630
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Summaries for Choroid Cancer

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MalaCards based summary : Choroid Cancer, also known as malignant tumor of the choroid, is related to ocular melanoma and melanoma, uveal. An important gene associated with Choroid Cancer is CYLC1 (Cylicin 1). The drugs Immunologic Factors and Immunoconjugates have been mentioned in the context of this disorder. Affiliated tissues include eye and brain.

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Related Diseases for Choroid Cancer

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Diseases related to Choroid Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 ocular melanoma 29.3 VEGFA BAP1
2 melanoma, uveal 28.0 VEGFA RAB31 PRAME MLANA LMCD1 EIF1B
3 epithelioid cell melanoma 10.1 MRPS21 MLANA
4 retinal detachment 10.1
5 conjunctival nevus 10.1 PRAME MLANA
6 mixed cell uveal melanoma 10.1 LMCD1 EIF1B
7 scleritis 10.0
8 posterior scleritis 9.9
9 endophthalmitis 9.9
10 vasculitis 9.9
11 vitreous detachment 9.9 VEGFA CYLC1
12 retinal perforation 9.9 VEGFA CYLC1
13 infiltrating angiolipoma 9.9 VEGFA MLANA
14 mucinous stomach adenocarcinoma 9.9 VEGFA MLANA
15 vascular cancer 9.8 VEGFA MLANA
16 angiomatous meningioma 9.8 VEGFA BAP1
17 castleman disease 9.8 VEGFA MLANA
18 sarcoidosis 1 9.8
19 lung cancer 9.8
20 macular degeneration, age-related, 1 9.8
21 granulomatosis with polyangiitis 9.8
22 common cold 9.8
23 choroiditis 9.8
24 retinal vasculitis 9.8
25 papilledema 9.8
26 adenocarcinoma 9.8
27 night blindness 9.8
28 iridocyclitis 9.8
29 posttransplant acute limbic encephalitis 9.8
30 rare tumor 9.8
31 mucosal melanoma 9.8 VEGFA BAP1
32 pleural cancer 9.7 VEGFA BAP1
33 neurofibroma 9.7 VEGFA MLANA
34 pleural disease 9.7 VEGFA BAP1
35 uveal disease 9.7 VEGFA BAP1
36 angiosarcoma 9.7 VEGFA MLANA
37 leiomyosarcoma 9.5 VEGFA MLANA
38 skin melanoma 9.4 VEGFA PRAME MLANA BAP1

Graphical network of the top 20 diseases related to Choroid Cancer:



Diseases related to Choroid Cancer
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Symptoms & Phenotypes for Choroid Cancer

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Drugs & Therapeutics for Choroid Cancer

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Drugs for Choroid Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunologic Factors Phase 1
2 Immunoconjugates Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Collaborative Ocular Melanoma Study (COMS) Unknown status NCT00000124 Phase 3
2 A Phase 1, Open-label, Multicenter Study Evaluating the Safety and Tolerability, Biologic Activity, Pharmacodynamics, and Pharmacokinetics of Single and Repeated Escalating Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma Who Are Planned to Undergo Enucleation or Brachytherapy Completed NCT02771340 Phase 1
3 Characterization of Small Choroidal Tumors Using Functional Optical Coherence Tomography Active, not recruiting NCT01955915
4 Validation of a Molecular Test for Predicting Metastasis in Patients With Uveal Melanoma Withdrawn NCT00406120

Search NIH Clinical Center for Choroid Cancer

Cochrane evidence based reviews: choroid neoplasms

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Genetic Tests for Choroid Cancer

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Anatomical Context for Choroid Cancer

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MalaCards organs/tissues related to Choroid Cancer:

40
Eye, Brain
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Publications for Choroid Cancer

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Articles related to Choroid Cancer:

# Title Authors PMID Year
1
[An analysis of the cause of misdiagnosis with ocular opportunistic infection]. 61
10437001 1997
2
Choroid plexus carcinoma. Case report. 61
8855084 1996
3
[Study of scleral perforations caused by choroid cancer]. 61
13472382 1957
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Variations for Choroid Cancer

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Expression for Choroid Cancer

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Search GEO for disease gene expression data for Choroid Cancer.
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Pathways for Choroid Cancer

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GO Terms for Choroid Cancer

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Sources for Choroid Cancer

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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