MCID: CHR008
MIFTS: 42

Choroiditis

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Choroiditis

MalaCards integrated aliases for Choroiditis:

Name: Choroiditis 12 76 53 44 15 73

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:11406
ICD10 33 H30.9
MeSH 44 D002833
NCIt 50 C35111
SNOMED-CT 68 16553002
UMLS 73 C0008526

Summaries for Choroiditis

MalaCards based summary : Choroiditis is related to punctate inner choroidopathy and central serous chorioretinopathy. An important gene associated with Choroiditis is ARMS2 (Age-Related Maculopathy Susceptibility 2), and among its related pathways/superpathways are Microglia Activation During Neuroinflammation: Microglia Polarization and Interleukin-10 signaling. The drugs Dexamethasone and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and lung.

Wikipedia : 76 Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina... more...

Related Diseases for Choroiditis

Diseases related to Choroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1004)
# Related Disease Score Top Affiliating Genes
1 punctate inner choroidopathy 32.6 IL10 TNF
2 central serous chorioretinopathy 32.6 ARMS2 CFH
3 multifocal choroiditis 32.5 ARMS2 CFB CFH HTRA1 IL10 TNF
4 posterior uveitis 31.9 CFH TNF
5 panuveitis 31.8 IL10 TNF
6 macular degeneration, age-related, 1 31.5 ARMS2 CFB CFH HTRA1 TNF
7 retinal disease 30.8 ARMS2 CFB CFH
8 kuhnt-junius degeneration 30.5 ARMS2 CFB CFH HTRA1
9 eales disease 30.4 IL10 TNF
10 intermediate uveitis 30.3 IL10 TNF
11 anterior uveitis 30.1 CFH TNF
12 toxoplasmosis 29.9 IL10 TNF
13 lyme disease 29.8 CFH TNF
14 membranoproliferative glomerulonephritis 29.6 CFB CFH
15 autoimmune uveitis 29.3 IL10 TNF
16 chlamydia 29.3 IL10 TNF
17 degeneration of macula and posterior pole 29.3 ARMS2 CFB CFH HTRA1
18 systemic lupus erythematosus 29.3 CFB CFH IL10 TNF
19 rubella 29.3 IL10 TNF
20 churg-strauss syndrome 29.1 IL10 TNF
21 complex regional pain syndrome 29.1 IL10 TNF
22 hepatitis a 29.1 IL10 TNF
23 human immunodeficiency virus infectious disease 29.1 IL10 TNF
24 spondyloarthropathy 29.1 IL10 TNF
25 aspergillosis 29.0 IL10 TNF
26 toxic shock syndrome 29.0 IL10 TNF
27 choroidal dystrophy, central areolar, 1 12.7
28 papilloma of choroid plexus 12.6
29 gyrate atrophy of choroid and retina 12.6
30 choroid plexus cancer 12.5
31 serpiginous choroiditis 12.5
32 choroid disease 12.4
33 choroid plexus cyst 12.4
34 choroidal dystrophy, central areolar 2 12.3
35 ataxia - hypogonadism - choroidal dystrophy 12.2
36 choroid spindle cell melanoma 12.2
37 atypical choroid plexus papilloma 12.2
38 malignant choroid melanoma 12.1
39 choroid plexus meningioma 12.1
40 choroidal osteoma, bilateral 12.1
41 hereditary choroidal atrophy 12.1
42 choroideremia 12.1
43 choroidal dystrophy, central areolar, 3 12.0
44 birdshot chorioretinopathy 12.0
45 adult choroid plexus cancer 12.0
46 choroid mixed cell melanoma 12.0
47 partial central choroid dystrophy 12.0
48 childhood choroid plexus cancer 12.0
49 choroid epithelioid cell melanoma 12.0
50 choroid necrotic melanoma 12.0

Graphical network of the top 20 diseases related to Choroiditis:



Diseases related to Choroiditis

Symptoms & Phenotypes for Choroiditis

Drugs & Therapeutics for Choroiditis

Drugs for Choroiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 80)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-02-2 5743
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 1177-87-3
3 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
4 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
5 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
6 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Not Applicable
7 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
8 BB 1101 Phase 4,Phase 3,Phase 2,Not Applicable
9
protease inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
10 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Not Applicable
11 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
12 Autonomic Agents Phase 4,Phase 3,Phase 2,Not Applicable
13 Antiemetics Phase 4,Phase 3,Phase 2,Not Applicable
14 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Not Applicable
15 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
16 beta-endorphin Phase 4
17 Adrenocorticotropic Hormone Phase 4
18 Melanocyte-Stimulating Hormones Phase 4
19 Immunosuppressive Agents Phase 4,Phase 3,Phase 1,Phase 2
20 Immunologic Factors Phase 4,Phase 3,Phase 1,Phase 2
21
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
22
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
23
leucovorin Approved Phase 3,Phase 1,Phase 2 58-05-9 6006 143
24
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
25
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
26
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
27
Sulfadiazine Approved, Investigational, Vet_approved Phase 3 68-35-9 5215
28
Pyrimethamine Approved, Investigational, Vet_approved Phase 3 58-14-0 4993
29
Bevacizumab Approved, Investigational Phase 3,Not Applicable 216974-75-3
30
Triamcinolone Approved, Vet_approved Phase 3,Phase 1,Phase 2 124-94-7 31307
31
Fluocinolone Acetonide Approved, Investigational, Vet_approved Phase 3,Not Applicable 67-73-2 6215
32
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
33
Mycophenolic acid Approved Phase 3 24280-93-1 446541
34
Methotrexate Approved Phase 3,Phase 1,Phase 2 59-05-2, 1959-05-2 126941
35
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 1,Phase 2 59-30-3 6037
36
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7
37 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
38 Antiprotozoal Agents Phase 3
39 Antiparasitic Agents Phase 3
40 Folic Acid Antagonists Phase 3,Phase 1,Phase 2
41 Vitamin B Complex Phase 3,Phase 1,Phase 2
42 Clindamycin palmitate Phase 3
43 Folate Phase 3,Phase 1,Phase 2
44 Antimalarials Phase 3
45 Anti-Infective Agents Phase 3,Phase 2,Phase 1
46 Prednisolone acetate Phase 3
47 Clindamycin phosphate Phase 3
48 Neuroprotective Agents Phase 3
49 Protective Agents Phase 3
50 Vitamin B9 Phase 3,Phase 1,Phase 2

Interventional clinical trials:

(show all 41)
# Name Status NCT ID Phase Drugs
1 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4 H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
2 Efficacy and Safety of H.P. Acthar® Gel in Subjects With Severe Noninfectious Intermediate Uveitis, Posterior Uveitis, or Panuveitis NIPPU Recruiting NCT03656692 Phase 4 Acthar
3 Study of the Effectiveness of Ozurdex for the Control of Uveitis Recruiting NCT02049476 Phase 4 Dexamethasone pellet
4 To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis Unknown status NCT00372294 Phase 3 pyrimethamine-sulfadiazine + prednisolone;Clindamycin+Dexamethasone
5 Intravitreal Bevacizumab for Inflammatory Neovascular Membranes Completed NCT00407121 Phase 3 Bevacizumab
6 Suprachoroidal Injection of CLS-TA in Subjects Non-infectious Uveitis Completed NCT03097315 Phase 3
7 A Controlled, Multi-center Study of the Utilization and Safety of the MK II Inserter and the Safety of the FAI Insert in Subjects With Non-infectious Uveitis Affecting the Posterior Segment of the Eye Completed NCT02748512 Phase 3 FAI insert
8 A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis Completed NCT00404742 Phase 3 Placebo;LX211;LX211;LX211
9 A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis Completed NCT00404612 Phase 3 Placebo;LX211;LX211;LX211
10 A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior Uveitis Completed NCT00333814 Phase 2, Phase 3 Dexamethasone;dexamethasone;Sham injection
11 Myfortic for the Treatment of Non-infectious Intermediate Uveitis Completed NCT01092533 Phase 3 Myfortic;Decortin
12 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Completed NCT02595398 Phase 3 4mg CLS-TA Suprachoriodal Injection;Sham Procedure
13 Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis Completed NCT00344253 Phase 3 Interferon beta;Methotrexate
14 Safety and Efficacy Study of a Fluocinolone Acetonide Intravitreal (FAI) Insert in Subjects With Chronic Non-infectious Posterior Uveitis Active, not recruiting NCT02746991 Phase 3 Sham Injection;FAI Insert
15 Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert Active, not recruiting NCT01694186 Phase 3 FAI insert;Sham injection
16 Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy Completed NCT00470977 Phase 1, Phase 2 ranibizumab injection (0.5 mg)
17 Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis Completed NCT01789320 Phase 1, Phase 2 triamcinolone acetonide (Triesence®)
18 Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis , Completed NCT01526889 Phase 2 LFG316;Conventional Therapy
19 Safety and Efficacy of AIN457 in Noninfectious Uveitis Completed NCT00685399 Phase 2 AIN457;AIN 457;AIN457
20 Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis Completed NCT01552044 Phase 1, Phase 2 Spironolactone;Placebo
21 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis Completed NCT02255032 Phase 2 4 mg CLS-TA;0.8 mg CLS-TA
22 Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a Completed NCT00508040 Phase 2 interferon alpha 2a;prednisone
23 Intravitreal Sirolimus as Therapeutic Approach to Uveitis Recruiting NCT01280669 Phase 2 Intravitreal injection 440mcg;Intravitreal injection of sirolimus 880mcg
24 Study of the Safety, Tolerability, and Bioactivity of Tocilizumab On Patients With Non-infectious UVEITIS: The STOP-UVEITIS Study Active, not recruiting NCT01717170 Phase 1, Phase 2 Tocilizumab
25 Safety and Preliminary Efficacy Study of V404 PDS in Uveitis Terminated NCT02125266 Phase 1, Phase 2 V404
26 Safety &Efficacy of CF101 to Subjects With Uveitis Withdrawn NCT01905124 Phase 2 CF101;Placebo
27 Sirolimus as Therapeutic Approach to Uveitis Completed NCT00908466 Phase 1 Sirolimus (rapamycin);Sirolimus (rapamycin)
28 Variations in Retinal Nerve Fiber Layer Thickness During Uncomplicated Anterior and Intermediate Uveitis Unknown status NCT02879084
29 Long-term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis With Active Choroidal Neovascularization Managed With Anti-vascular Endothelial Growth Factor Completed NCT03793400 Bevacizumab Injection
30 Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular Neovascularization Completed NCT00645697
31 Evaluation and Treatment of Patients With Inflammatory Eye Diseases Completed NCT00006188
32 Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301 Completed NCT02952001 4mg CLS-TA Suprachoriodal Injection
33 Retisert and Cataract Surgery in Patients With Severe Uveitis Completed NCT00570830 Not Applicable
34 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438 Not Applicable Anti-toxoplasmosis treatment;Anti-inflammatory treatments
35 Quality of Life in Patients With Intermediate Uveitis Completed NCT01314469
36 A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD) Active, not recruiting NCT02941991
37 Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Patients With AMD Active, not recruiting NCT02463344
38 Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Stargardt Macular Dystrophy Patients Active, not recruiting NCT02445612
39 Ocular Manifestations in Rheumatic Diseases Active, not recruiting NCT03753893
40 Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD Withdrawn NCT01256580 Not Applicable Bevacizumab (Avastin; Genentech, Inc.);Bevacizumab, Dexamethasone, Verteporfin Photodynamic Therapy
41 Postnatal HCMV Infection in Very Preterm Infants. Implications, Morbidity, Growth and Neurodevelopmental Outcomes. Withdrawn NCT01151462

Search NIH Clinical Center for Choroiditis

Cochrane evidence based reviews: choroiditis

Genetic Tests for Choroiditis

Anatomical Context for Choroiditis

MalaCards organs/tissues related to Choroiditis:

41
Retina, Eye, Lung, Bone, Kidney, Testes, Thyroid

Publications for Choroiditis

Articles related to Choroiditis:

(show top 50) (show all 494)
# Title Authors Year
1
Need for Quantitative Measurement Methods for Posterior Uveitis: Comparison of Dual FA/ICGA Angiography, EDI-OCT Choroidal Thickness and SUN Vitreous Haze Evaluation in Stromal Choroiditis. ( 29669371 )
2018
2
Optical Coherence Tomography Features of Tuberculous Serpiginous-like Choroiditis and Serpiginous Choroiditis. ( 29866214 )
2018
3
Multimodal Imaging of Post-Infectious Unilateral Outer Retinopathy and Choroiditis. ( 29953300 )
2018
4
CHORIOCAPILLARIS FLOW VOIDS IN CRYPTOCOCCAL CHOROIDITIS USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. ( 29373342 )
2018
5
Multimodal Imaging to Monitor Recurrent Serpiginous Choroiditis. ( 29937127 )
2018
6
Enhanced Depth Imaging by High-Resolution Spectral Domain Optical Coherence Tomography in Tubercular Multifocal Serpiginoid Choroiditis. ( 29787321 )
2018
7
Assessment of measurement methods of posterior inflammation in stromal choroiditis: the value of quantitative outcome measures versus the presently qualitatively based paradigm. ( 29946830 )
2018
8
Bilateral Asymptomatic Cryptococcal Retinitis without Choroiditis or Vitritis. ( 29566868 )
2018
9
TREATMENT OF REFRACTORY TUBERCULAR SERPIGINOUS-LIKE CHOROIDITIS WITH INTRAVITREAL METHOTREXATE. ( 29979252 )
2018
10
Clinicopathologic Features of Tuberculous Serpiginous-like Choroiditis. ( 29270629 )
2018
11
Cryptococcal choroiditis in advanced AIDS with clinicopathologic correlation. ( 29780913 )
2018
12
Optical coherence tomography angiography and choroidal neovascularization in multifocal choroiditis: A descriptive study. ( 29569477 )
2018
13
Scleroderma-related choroiditis. ( 29563704 )
2018
14
An efficacy analysis of anti-vascular endothelial growth factor therapy for choroidal neovascularization secondary to multifocal choroiditis and comparison with wet age-related macular degeneration. ( 29616508 )
2018
15
Quantitative polymerase chain reaction analysis of serpiginous choroiditis with biopsy-proven testicular tuberculosis. ( 29380793 )
2018
16
Case of cryptococcal choroiditis in adult with T-cell leukemia/lymphoma. ( 30057340 )
2018
17
TUBERCULOUS CHOROIDITIS IN PATIENT WITH VOGT-KOYANAGI-HARADA DISEASE. ( 30074567 )
2018
18
Multimodal Evaluation of Presumed Tuberculous Serpiginous-Like Choroiditis. ( 30081660 )
2018
19
Swept-Source OCT Angiography of Serpiginous Choroiditis. ( 30148243 )
2018
20
Longitudinal analysis of serum cytokine profile among patients with tubercular multifocal serpiginoid choroiditis: a pilot study. ( 30185832 )
2018
21
Correlation of "Panoramic" Optical Coherence Tomography Angiography With Indocyanine Green Angiography Characteristics of Serpiginous-Like Choroiditis. ( 30457645 )
2018
22
Macular serpiginous choroiditis - case report. ( 30505991 )
2018
23
Multifocal Choroiditis with Peripheral Subretinal Fibrosis and Optic Nerve Involvement. ( 28734337 )
2017
24
Dengue associated choroiditis: a rare entity. ( 28560576 )
2017
25
Central serous chorioretinopathy mimicking as choroiditis. ( 29134698 )
2017
26
Ultra-Wide Field Imaging in Paradoxical Worsening of Tubercular Multifocal Serpiginoid Choroiditis after the Initiation of Anti-Tubercular Therapy. ( 29020501 )
2017
27
Role of Angiography in Systemic Lupus Erythematosus-Induced Choroiditis. ( 28362518 )
2017
28
Swept-source optical coherence tomography angiography in serpiginous choroiditis. ( 28982952 )
2017
29
Multimodal Evaluation of Patients with Acute Posterior Multifocal Placoid Pigment Epitheliopathy and Serpiginous Choroiditis. ( 28960121 )
2017
30
Forme fruste focal choroidal excavation in a case of serpiginous choroiditis. ( 28965349 )
2017
31
IDIOPATHIC MULTIFOCAL CHOROIDITIS PRESENTING WITH A TRANSIENT PERIPAPILLARY WHITE RING. ( 29176533 )
2017
32
Serpiginous Choroiditis. ( 28418567 )
2017
33
Multifocal choroiditis as the first sign of systemic sarcoidosis associated with pembrolizumab. ( 29503956 )
2017
34
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO DISTINGUISH CHOROIDAL NEOVASCULARIZATION FROM MACULAR INFLAMMATORY LESIONS IN MULTIFOCAL CHOROIDITIS. ( 28368976 )
2017
35
Clinical Outcomes of Adjunctive Sustained-Release Intravitreal Dexamethasone Implants in Tuberculosis-Associated Multifocal Serpigenoid Choroiditis. ( 29020496 )
2017
36
Bilateral choroiditis as the only sign of persistent Mycobacterium intracellulare infection following haematogenous spread in an immunocompromised patient. ( 29224191 )
2017
37
Multifocal Choroiditis with Retinal Vasculitis, Optic Neuropathy, and Keratoconus in a Young Saudi Male. ( 28936058 )
2017
38
Choroidal neovascularization in multifocal choroiditis after dabrafenib and trametinib. ( 28777388 )
2017
39
How to Differentiate Myopic Choroidal Neovascularization, Idiopathic Multifocal Choroiditis, and Punctate Inner Choroidopathy Using Clinical and Multimodal Imaging Findings. ( 28297030 )
2017
40
Splenic tuberculosis and multifocal serpiginoid choroiditis. ( 28798995 )
2017
41
Multifocal Choroiditis and Panuveitis - difficulties in diagnosis and treatment. ( 29516050 )
2017
42
Treatment Results in Serpiginous Choroiditis and Multifocal Serpiginoid Choroiditis Associated with Latent Tuberculosis. ( 28405483 )
2017
43
Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis. ( 29020533 )
2017
44
Multimodal Imaging Including Optical Coherence Tomography Angiography in Serpiginous Choroiditis. ( 28281863 )
2017
45
Paradoxical worsening of a case of TB subretinal abscess with serpiginous-like choroiditis following the initiation of antitubercular therapy. ( 28820170 )
2017
46
CHORIORETINAL WHITE DOT LESIONS IN EYES WITH MULTIFOCAL CHOROIDITIS AND TILTED DISK SYNDROME WITH INFERIOR STAPHYLOMA. ( 27380431 )
2016
47
Optical Coherence Tomography Angiography Features of Paradoxical Worsening in Tubercular Multifocal Serpiginoid Choroiditis. ( 27598542 )
2016
48
MACULA RETINAL VASCULITIS AND CHOROIDITIS ASSOCIATED WITH GRANULOMATOSIS WITH POLYANGIITIS. ( 27305849 )
2016
49
Enhanced depth imaging is less suited than indocyanine green angiography for close monitoring of primary stromal choroiditis: a pilot report. ( 27486023 )
2016
50
Short-term Intensive Immunosuppression: A Randomized, Three-arm Study of Intravenous Pulse Methylprednisolone and Cyclophosphamide in Macular Serpiginous Choroiditis. ( 27849419 )
2016

Variations for Choroiditis

Expression for Choroiditis

Search GEO for disease gene expression data for Choroiditis.

Pathways for Choroiditis

Pathways related to Choroiditis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.26 IL10 TNF
2 11.06 IL10 TNF
3 11.01 IL10 TNF
4 10.8 IL10 TNF
5 10.7 IL10 TNF
6 10.55 CFB CFH IL10
7 10.42 IL10 TNF

GO Terms for Choroiditis

Cellular components related to Choroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CFB CFH HTRA1 IL10 TNF
2 extracellular space GO:0005615 9.02 CFB CFH HTRA1 IL10 TNF

Biological processes related to Choroiditis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 response to glucocorticoid GO:0051384 9.51 IL10 TNF
2 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.49 IL10 TNF
3 negative regulation of mitotic cell cycle GO:0045930 9.48 IL10 TNF
4 negative regulation of interleukin-6 production GO:0032715 9.46 IL10 TNF
5 positive regulation of cytokine secretion GO:0050715 9.43 IL10 TNF
6 regulation of synapse organization GO:0050807 9.4 IL10 TNF
7 negative regulation of growth of symbiont in host GO:0044130 9.37 IL10 TNF
8 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.32 IL10 TNF
9 complement activation, alternative pathway GO:0006957 9.26 CFB CFH
10 endothelial cell apoptotic process GO:0072577 9.16 IL10 TNF
11 negative regulation of cytokine secretion involved in immune response GO:0002740 8.96 IL10 TNF
12 receptor biosynthetic process GO:0032800 8.62 IL10 TNF

Sources for Choroiditis

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17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
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34 ICD10 via Orphanet
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