MCID: CHR008
MIFTS: 48

Choroiditis

Categories: Eye diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Choroiditis

MalaCards integrated aliases for Choroiditis:

Name: Choroiditis 12 73 20 44 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:11406
MeSH 44 D002833
NCIt 50 C35111
SNOMED-CT 67 16553002
ICD10 32 H30.9
UMLS 70 C0008526

Summaries for Choroiditis

MalaCards based summary : Choroiditis is related to punctate inner choroidopathy and multifocal choroiditis. An important gene associated with Choroiditis is CFH (Complement Factor H), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Allograft rejection. The drugs Iodine and Lactitol have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial, and related phenotypes are growth/size/body region and cardiovascular system

Wikipedia : 73 Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina... more...

Related Diseases for Choroiditis

Diseases related to Choroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 630)
# Related Disease Score Top Affiliating Genes
1 punctate inner choroidopathy 32.3 TNF IL10
2 multifocal choroiditis 32.1 TNF IL10 HTRA1 CFH CFB ARMS2
3 posterior uveitis 31.1 TNF SAG RBP3 IFNG CFH
4 central serous chorioretinopathy 30.6 CFH ARMS2
5 neuroretinitis 30.5 SAG CD4 ACE
6 macular retinal edema 30.5 VEGFA TNF CFH ACE
7 retinal detachment 30.4 VEGFA TNF IL10 IFNG
8 ocular tuberculosis 30.4 IFNG CD4 ACE
9 histoplasmosis 30.3 TNF IFNG CFH CD4 ARMS2
10 optic neuritis 30.2 VEGFA TNF IL10
11 acquired immunodeficiency syndrome 30.2 TNF IL10 IFNG CD4
12 lyme disease 30.1 TNF IL17A CFH
13 cryptococcal meningitis 30.1 VEGFA IFNG CD4
14 sympathetic ophthalmia 30.1 TNF RBP3 IL10
15 retinal vascular disease 30.1 VEGFA TNF ACE
16 chickenpox 30.0 TNF IL10 IFNG CD4
17 vogt-koyanagi-harada disease 30.0 IL17A IL10 IFNG
18 optic papillitis 30.0 SAG RBP3 CD4 ACE
19 chorioretinal scar 30.0 VEGFA ABCA4
20 neuritis 30.0 VEGFA TNF IL10 IFNG
21 yemenite deaf-blind hypopigmentation syndrome 29.9 VEGFA CFH ABCA4
22 degenerative myopia 29.9 VEGFA CFH ARMS2
23 herpes zoster 29.8 TNF IL10 IFNG CD4
24 chronic graft versus host disease 29.8 IL10 IFNG
25 retinal vasculitis 29.8 TNF SAG RBP3 CD4 ACE
26 posterior scleritis 29.8 VEGFA TNF ACE
27 juvenile rheumatoid arthritis 29.8 TNF IL10 IFNG
28 retinal disease 29.8 SAG CFH CFB ARMS2 ABCA4
29 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 29.8 IL17A IL10 IFNG
30 cat-scratch disease 29.8 HTRA1 CD4 ACE
31 listeriosis 29.8 TNF IL10 CD4
32 cytomegalovirus retinitis 29.8 TNF IL10 IFNG CD4
33 optic nerve disease 29.8 VEGFA TNF IL17A CD4
34 meningoencephalitis 29.8 TNF IL10 CD4
35 retinal vein occlusion 29.7 VEGFA TNF ACE
36 granulomatous hepatitis 29.7 TNF CD4 ACE
37 endophthalmitis 29.7 VEGFA TNF SAG
38 toxoplasmosis 29.7 TNF IL10 IFNG ABCA4
39 autoimmune hepatitis 29.7 TNF IL17A IL10
40 vitiligo-associated multiple autoimmune disease susceptibility 1 29.7 TNF IL17A CD4
41 human immunodeficiency virus type 1 29.7 TNF IL10 IFNG CD4
42 papilledema 29.7 VEGFA CD4 ACE
43 graft-versus-host disease 29.7 TNF IL10 IFNG
44 dengue disease 29.7 TNF IL10 IFNG
45 blau syndrome 29.7 TNF NOD2 IL10
46 cardiac sarcoidosis 29.6 TNF IFNG ACE
47 sarcoidosis 1 29.6 TNF NOD2 IFNG CD4 ACE
48 miliary tuberculosis 29.6 TNF IFNG CD4
49 sporotrichosis 29.6 IL10 IFNG CD4
50 pulmonary tuberculosis 29.6 TNF IL10 IFNG

Graphical network of the top 20 diseases related to Choroiditis:



Diseases related to Choroiditis

Symptoms & Phenotypes for Choroiditis

MGI Mouse Phenotypes related to Choroiditis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.18 ACE CD4 CFB CFH HTRA1 IFNG
2 cardiovascular system MP:0005385 10.11 ABCA4 ACE CFB CFH HTRA1 IFNG
3 hematopoietic system MP:0005397 10.11 ABCA4 ACE CD4 CFB CFH IFNG
4 homeostasis/metabolism MP:0005376 10.1 ABCA4 ACE CD4 CFB CFH IFNG
5 digestive/alimentary MP:0005381 9.98 CD4 IFNG IL10 IL17A NOD2 TNF
6 immune system MP:0005387 9.96 ACE CD4 CFB CFH IFNG IL10
7 nervous system MP:0003631 9.85 ABCA4 ACE CD4 CFH IFNG IL10
8 skeleton MP:0005390 9.61 ABCA4 CFB HTRA1 IFNG IL10 IL17A
9 vision/eye MP:0005391 9.32 ABCA4 ACE CFH HTRA1 IFNG IL10

Drugs & Therapeutics for Choroiditis

Drugs for Choroiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 260)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Iodine Approved, Investigational Phase 4 7553-56-2 807
2
Lactitol Approved, Investigational Phase 4 585-86-4 157355
3
Povidone Approved Phase 4 9003-39-8 131751496
4
Povidone-iodine Approved Phase 4 25655-41-8
5
Ofloxacin Approved Phase 4 82419-36-1 4583
6
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
7
Latanoprost Approved, Investigational Phase 4 130209-82-4 5282380 5311221
8
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
9
Travoprost Approved Phase 4 157283-68-6 5282226
10
Dorzolamide Approved Phase 4 120279-96-1 3154 5284549
11
Bimatoprost Approved, Investigational Phase 4 155206-00-1 5311027
12
Brinzolamide Approved Phase 4 138890-62-7 68844
13
Timolol Approved Phase 4 26839-75-8 33624 5478
14
Clonidine Approved Phase 4 4205-90-7 2803
15
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
16
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
17
Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
18
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
19
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
20
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
21
Alfuzosin Approved, Investigational Phase 4 81403-80-7 2092
22
Tamsulosin Approved, Investigational Phase 4 106133-20-4 129211
23
Empagliflozin Approved Phase 4 864070-44-0
24
Dipivefrin Approved Phase 4 52365-63-6 3105
25
Moxifloxacin Approved, Investigational Phase 4 151096-09-2, 354812-41-2 152946
26
Bevacizumab Approved, Investigational Phase 4 216974-75-3
27
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 68-26-8, 11103-57-4 445354
28
Cadexomer iodine Experimental Phase 4 94820-09-4
29
Maleic acid Experimental Phase 4 110-16-7 444266
30
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
31 Adrenergic alpha-Agonists Phase 4
32 Adrenergic Agonists Phase 4
33 Respiratory System Agents Phase 4
34 Neurotransmitter Agents Phase 4
35 Mydriatics Phase 4
36 Adrenergic Agents Phase 4
37 Antihypertensive Agents Phase 4
38 Antineoplastic Agents, Hormonal Phase 4
39 Pharmaceutical Solutions Phase 4
40 Ophthalmic Solutions Phase 4
41 Contraceptives, Oral, Combined Phase 4
42 Contraceptives, Oral Phase 4
43 Drospirenone and ethinyl estradiol combination Phase 4
44 Contraceptive Agents Phase 4
45 Anti-Arrhythmia Agents Phase 4
46 Anti-Asthmatic Agents Phase 4
47 Parasympatholytics Phase 4
48 Cholinergic Agents Phase 4
49 Cholinergic Antagonists Phase 4
50 Muscarinic Antagonists Phase 4

Interventional clinical trials:

(show top 50) (show all 376)
# Name Status NCT ID Phase Drugs
1 Open-label, Non-randomized, Unmasked, Study of IAI in Patients Which Choroidal Neovascularization Secondary to Polypoidal Choroidal Vasculopathy (PCV) Unknown status NCT02092532 Phase 4 Rescue Intravitreal Aflibercept Injection
2 Assessment in Early Changes in the Parameters of Optical Coherence Tomography (OCT Spectral Domain) in Patients With Subfoveal Neovascular Membranes Related to Age After Treatment With a Single Intravitreal Injection of Lucentis. Unknown status NCT01669447 Phase 4
3 Ranibizumabe Intravitreal Injection for Myopic Choroidal Neovascularization Unknown status NCT01246089 Phase 4 ranibizumab injection
4 Aflibercept Intravitreal Injection for Myopic Choroidal Neovascularization Unknown status NCT02033018 Phase 4 Aflibercept Injection
5 The Efficacy Assessment of Intravitreal Injection of Conbercept in Patients With Polypoidal Choroidal Vasculopathy (PCV) Unknown status NCT03159884 Phase 4 Conbercept
6 Phase IV Clinical Trial (STAR Study) Extension Study of Conbercept Ophthalmic Injection for Treatment of Polypoid Choroidal Vasculopathy Unknown status NCT03244657 Phase 4 conbercept ophthalmic injection (0.5mg);conbercept ophthalmic injection (0.5mg)
7 Multicenter Randomized Controlled Study of Intravitreal Ranibizumab and Triamcinolone Acetonide Combination Therapy Versus Ranibizumab Monotherapy in Patients With Polypoidal Choroidal Vasculopathy Unknown status NCT02806752 Phase 4 Triamcinolone Acetonide;Ranibizumab
8 A Randomized Control Trial of Intravitreal Ranibizumab (Lucentis) for the Prevention of Radiation Maculopathy Following Plaque Radiotherapy for Choroidal Melanoma Unknown status NCT00540930 Phase 4 Ranibizumab
9 Transpupillary Thermotherapy (TTT) Alone Versus the Combined Therapy Consisting of TTT and Intravitreal Injection of Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy Unknown status NCT02379000 Phase 4 Triamcinolone Acetonide
10 A Randomised Controlled Trial of Epimacular Brachytherapy Versus Ranibizumab Monotherapy for the Treatment of Subfoveal Choroidal Neovascularisation Associated With Wet Age-related Macular Degeneration in Patients Who Have Commenced Anti-VEGF Therapy Completed NCT01006538 Phase 4 Ranibizumab
11 Efficacy and Safety of Initial Versus Delayed Verteporfin Photodynamic Therapy in Combination With Conbercept in Patients With Symptomatic Polypoidal Choroidal Vasculopathy Completed NCT02821520 Phase 4 conbercept
12 A Multicentre, Randomized, Double Masked, Exploratory, Indocyanine Green Angiography (ICGA) Guided Study of 6 Months Duration to Compare the Safety and Effect on Polyp Regression of Verteporfin Photodynamic Therapy (PDT) Alone or Added to Ranibizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy Completed NCT00674323 Phase 4 Verteporfin Photodynamic Therapy;Ranibizumab
13 A Study to Investigate the Safety and Efficacy of Lucentis (Ranibizumab) in Patients With CNV Due to Causes Other Than AMD and in Patients Where Pigment Epithelial Detachments Are the Primary Manifestation of Their AMD. Completed NCT01628354 Phase 4 Ranibizumab
14 A Phase IV, Long-term, Open-label, Multicenter Extension Study to Evaluate the Safety and Tolerability of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD) Completed NCT00504959 Phase 4 ranibizumab
15 A Randomized, Double-masked, Sham-controlled Phase 4 Study of the Efficacy, Safety, and Tolerability of IV Aflibercept Monotherapy Compared to Aflibercept With Adjunctive Photodynamic Therapy in Patients With PCV. Completed NCT02495181 Phase 4 Intravitreal Aflibercept
16 SD-OCT-guided Intravitreal Ranibizumab Treatment in Choroidal Neovascularization Due to Myopia Completed NCT03409250 Phase 4 Ranibizumab, Lucentis
17 Time Course of Activity Signs at High Resolution OCT During OCT-guided High Frequency Intravitreal Ranibizumab Treatment in Choroidal Neovascularization Due to Age Related Macular Degeneration Completed NCT03393767 Phase 4 Ranibizumab
18 Intravitreal Aflibercept for Treatment of Polypoidal Choroidal Vasculopathy (PCV) Completed NCT02860858 Phase 4
19 Bevacizumab Intravitreal for Myopic Choroidal Neovascularization Completed NCT00797992 Phase 4 Injection
20 Efficacy of Aflibercept (Eylea®) on Choroidal Neovascularization (Type 3) Completed NCT02320474 Phase 4 Aflibercept
21 Intravitreal Aflibercept Injection for Polypoidal Choroidal Vasculopathy With Hemorrhage or Exudation Completed NCT01871376 Phase 4 Intravitreal aflibercept injection 2.0mg
22 Efficacy and Safety of Intravitreal Vascular Endothelial Growth Factor Trap-eye in Patients With Polyploidal Choroidal Vasculopathy Completed NCT02072408 Phase 4 aflibercept
23 A Phase IV, Randomised, Single Masked Study Investigating the Efficacy and Safety of Ranibizumab "Inject and Extend" Using an Intensive Retinal Fluid Retreatment Regimen Compared to a Relaxed Retinal Fluid Retreatment Regimen in Patients With Wet Age-related Macular Degeneration (AMD) Completed NCT01972789 Phase 4 Ranibizumab
24 Dosing Strategy of Intravitreal Ranibizumab for Myopia Choroidal Neovascularization: a Single Center Randomized Prospective Study Completed NCT03042871 Phase 4 0.5mg intravitreal ranibizumab
25 Choroidal Neovascular Membrane Recurrence Rate in Wet AMD Patients Stable on Three Month Ranibizumab Dosing Completed NCT01453920 Phase 4 Ranibizumab;Ranibizumab
26 The Effect of Oral Contraceptive Pills On Macula, Retinal Nerve Fiber Layer and Choroid Thickness Completed NCT02841202 Phase 4 oral contraceptive pills
27 The Effects of Low Dose Atropine on Choroidal Thickness Completed NCT03544827 Phase 4 Atropine;Atropine
28 Comparison of Safety, Effectiveness, and Quality-of-life Outcomes Between Labeled Versus "Treat and Extend" Regimen in Turkish Patients With Choroidal Neovascularisation Due to AMD Completed NCT01148511 Phase 4 Ranibizumab 0.5 mg
29 A Randomized, Double-masked, Sham-controlled Phase 3b/4 Study of the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Monotherapy Compared to Aflibercept With Adjunctive Photodynamic Therapy as Indicated in Subjects With Polypoidal Choroidal Vasculopathy Completed NCT02120950 Phase 4 Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
30 A 24-month, Phase IV, Randomized, Double Masked, Multi-center Study of Ranibizumab Monotherapy or Ranibizumab in Combination With Verteporfin Photodynamic Therapy on Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy Completed NCT01846273 Phase 4 Ranibizumab;Verteporfin PDT;Sham PDT
31 Choroidal Thickness and Its Correlations With Ocular Parameters in Cases With Primary Open-angle Glaucoma Completed NCT03966560 Phase 4 Brimonidine Tartrate;Dorzolamide (as Dorzolamide Hydrochloride) 20 Mg/mL and Timolol (as Timolol Maleate) 5 Mg/mL Eye Drops;Brinzolamide/Timolol 10 MG/1 ML-5 MG/1 ML Ophthalmic Suspension;Travoprost and Timolol;Bimatoprost and Timolol;Latanoprost
32 An Single Arm, Single Dose Study to Evaluate the Effect of Intravitreal Injection of VEGF-Trap Eye on Polypoidal Choroidal Vasculopathy Completed NCT01950741 Phase 4 aflibercept
33 Clinical Research of Photodynamic Therapy for Exudative Age-related Macular Degeneration Accompanied With Polypoidal Choroidal Vasculopathy Completed NCT00331435 Phase 4
34 Effects of Topical Clonidine vs. Brimonidine on Choroidal Blood Flow and Intraocular Pressure During Isometric Exercise Completed NCT00312416 Phase 4 Clonidin;Brimonidine
35 Effect of High-Dose Prednisolone (Solu Dacortin®) Treatment on Choroidal and Optic Nerve Head Blood Flow in Humans Completed NCT00312325 Phase 4 Prednisolone
36 Influence of Travoprost 0.004% and Latanoprost 0.005% on Retinal Vascular Diameter and Choroidal Blood Flow in Glaucoma Patients Completed NCT00308945 Phase 4 travoprost 0.004% (drug);latanoprost 0.005% (drug)
37 An Open-Label, Multicenter, Phase 4 Study of the Effect of Verteporfin for Injection Therapy in Subjects With Occult With No Classic Choroidal NeoVascularization Secondary to Age-Related Macular Degeneration Completed NCT00135837 Phase 4 Verteporfin for injection
38 Efficacy of Ranibizumab Treatment Every 2 Month Compared to Treatment on Demand on Patients With Choroidal Neo-vascularization (CNV) as a Consequence of Age-related Macular Degeneration (AMD) Completed NCT01831947 Phase 4
39 The Influence of Atropine on Choroidal Thickness Completed NCT03158142 Phase 4 Atropine Sulfate 1% Oph Soln
40 The Effects of Systemic Alfuzosin and Tamsulosin Hydrochloride on Choroidal Thickness and Pupil Diameter Sizes in Cases With Benign Prostatic Hyperplasia Completed NCT03144596 Phase 4 Alfuzosin Hydrochloride 10 MG;Tamsulosin Hydrochloride 0.4 MG
41 Effect of Sodium Glucose co Transporter 2 (SGLT2) Inhibition on Optical Coherence Tomography Angiography (OCT-A) Parameters in Diabetic Chronic Kidney Disease (CKD) Recruiting NCT04215445 Phase 4 Empagliflozin 25 MG
42 PRedictive Factors and Changes From Treatment in Idiopathic Polypoidal Choroidal Vasuclopathy Versus Central Serous Chorioretinopathy Versus Neovascular Age Related Macular Degeneration With afLibercept Recruiting NCT02681783 Phase 4 aflibercept
43 Subtenons Triamcinolone Acetonide Injections for Treatment of Persistent Choroidal Effusions Post Glaucoma Surgery Recruiting NCT02917564 Phase 4 Triamcinolone Acetonide 1 ml of 40 mg/mL suspension
44 Evaluation and Comparison of Macular and Choroidal Thickness After Intracameral Moxifloxacin for Prevention of Postcataract Endophthalmitis Recruiting NCT03363295 Phase 4 Moxifloxacin Injection
45 Intraocular Cytokine Changes in Recurrence of Polypoidal Choroidal Vasculopathy Active, not recruiting NCT02976194 Phase 4 ranibizumab
46 An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy Using a Modified Intensive Treat and Extend Regime to a Fixed Dosing Regimen Active, not recruiting NCT03117634 Phase 4 Treat and Extend with Aflibercept 2mg;Fixed Dosing with Aflibercept 2mg
47 A Random, Open-label Multicenter, Phase IV Study Assessing the Efficacy and Safety of Two Regimens of Anti-VEGF Therapy in Chinese Patients With Polypoidal Choroidal Vasculopathy Not yet recruiting NCT04380974 Phase 4 Anti-VEGF drug
48 A 102-Week, Open Label, Multicenter Trial To Investigate The Efficacy Of Macugen For The Preservation Of Visual Function In Subjects With Neovascular Age-Related Macular Degeneration (AMD) And To Assess The Benefit Of Treating Early Choroidal Neovascularization (CNV). Terminated NCT00327470 Phase 4 Pegaptanib Sodium 0.3 mg
49 Triple Treatment for Detachment of Retinal Pigment Epithelium Secondary to Polypoidal Choroidal Vasculopathy. Withdrawn NCT01666236 Phase 4
50 Randomized, Double Blind, Controlled Study With Verteporfin Photodynamic Therapy And Intravitreal Triamcinolone(IVTA) Vs Triple Therapy With Verteporfin Photodynamic Therapy, Intravitreal Triamcinolone And Intravitreal Ranibizumab In Patients With Subfoveal Choroidal Neovascularization(CNV) Secondary To Age-Related Macular Degeneration(AMD) Unknown status NCT00930189 Phase 2, Phase 3 intravitreal injection of ranibizumab;intravitreal injection of triamcinolone

Search NIH Clinical Center for Choroiditis

Cochrane evidence based reviews: choroiditis

Genetic Tests for Choroiditis

Anatomical Context for Choroiditis

MalaCards organs/tissues related to Choroiditis:

40
Eye, Retina, Endothelial, Lung, Skin, Kidney, Liver

Publications for Choroiditis

Articles related to Choroiditis:

(show top 50) (show all 1287)
# Title Authors PMID Year
1
Atypical unilateral multifocal choroiditis in a COVID-19 positive patient. 61
33623832 2021
2
Coats like response in healed choroiditis. 61
33797302 2021
3
LONGITUDINAL FOLLOW-UP OF TUBERCULAR SERPIGINOUS-LIKE CHOROIDITIS USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. 61
32833411 2021
4
Re: Fung et al.: Focal scleral nodule: a new name for solitary idiopathic choroiditis and unifocal helioid choroiditis (Ophthalmology. 2020;127:1567-1577). 61
33423800 2021
5
Chlorambucil combination therapy in refractory serpiginous choroiditis: A cure? 61
33615036 2021
6
Swept source OCTA reveals a link between choriocapillaris blood flow and vision loss in a case of tubercular serpiginous-like choroiditis. 61
33553805 2021
7
The evolution of an active solitary idiopathic choroiditis (focal scleral nodule): a case report of the natural course and a review of the literature. 61
33750335 2021
8
A Case Series of "Solitary Idiopathic Choroiditis" and Proposal of a Nomenclature Change to "Idiopathic Scleroma". 61
33796517 2021
9
TREATMENT OF REFRACTORY TUBERCULAR SERPIGINOUS-LIKE CHOROIDITIS WITH INTRAVITREAL METHOTREXATE. 61
29979252 2021
10
Chorioretinal Atrophy in Punctate Inner Choroidopathy/multifocal Choroiditis: A Five-year Follow-up Study. 61
33684021 2021
11
Pathogenesis of ocular toxoplasmosis. 61
32717377 2021
12
Characterization of Clinical and Immune Responses in an Experimental Chronic Autoimmune Uveitis Model. 61
32966818 2021
13
Systemic associations of sarcoid uveitis: correlation with uveitis phenotype and ethnicity. 61
33737030 2021
14
CHOROIDAL GRANULOMAS VISUALIZED BY SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. 61
32467485 2021
15
Ocular manifestations of disseminated Mycobacterium chimaera infection after cardiothoracic surgery. 61
33775595 2021
16
Vogt-Koyanagi-Harada disease is always bilateral: reports of unilateral cases failed to use choroidal investigations showing subclinical involvement of the fellow eye. 61
33559795 2021
17
Review of the Current Literature and Our Experience on the Value of OCT-angiography in White Dot Syndromes. 61
33617412 2021
18
Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis-Report 1: Guidelines for Initiating Antitubercular Therapy in Tubercular Choroiditis. 61
32115264 2021
19
Prognosis of Ocular Tuberculosis Following Long-Term Antitubercular Therapy. 61
33524301 2021
20
Clinical and Multimodal Imaging Findings in Disseminated Mycobacterium Chimaera. 61
32623074 2021
21
[Unilateral serpiginous choroiditis secondary to ocular tuberculosis]. 61
33010948 2021
22
Incidence of ocular inflammation among patients with active tuberculosis or nontuberculous mycobacterial infections in a tertiary hospital in Japan. 61
33475908 2021
23
Unilateral macular serpiginous-like choroiditis as the initial manifestation of presumed ocular tuberculosis. 61
33397439 2021
24
Use of multimodal analysis in the diagnosis and follow-up of a case of Acute Zonal Occult Outer Retinopathy (AZOOR). 61
33485739 2021
25
Placoid lesions of the retina: progress in multimodal imaging and clinical perspective. 61
33468489 2021
26
Efficacy and safety of immunomodulatory drugs in patients with non-infectious intermediate and posterior uveitis, panuveitis and macular edema: A systematic literature review. 61
33065425 2020
27
The efficacy of adalimumab in treating patients with central multifocal choroiditis. 61
33024886 2020
28
Serpiginous choroiditis presenting after SARS-CoV-2 infection: A new immunological trigger? 61
33267645 2020
29
[Fundus imaging features of purified protein derivative and T-spot positive tubercular serpiginous-like choroiditis]. 61
33342117 2020
30
The efficacy of corticosteroid-sparing immunomodulatory therapy in treating patients with central multifocal choroiditis. 61
32410393 2020
31
Clinical and Imaging Factors Associated With the Outcomes of Tubercular Serpiginous-like Choroiditis. 61
32710829 2020
32
Submacular choroiditis in common variable immunodeficiency associated with a pathogenic mutation in the tumor necrosis factor gene. 61
32984650 2020
33
Reactive AA Amyloidosis in the setting of infective endocarditis manifesting as bilateral orbitopathy and choroidopathy. 61
33394958 2020
34
Ocular manifestations of Blau syndrome. 61
33009086 2020
35
Re: Agrawal et al.: Collaborative Ocular Tuberculosis Study consensus guidelines on the management of tubercular uveitis-report 1: Guidelines for initiating antitubercular therapy in tubercular choroiditis (Ophthalmology. 2020 Jan 11;S0161-6420(20)30013-0. https://doi.org/10.1016/j.ophtha.2020.01.008 [Epub ahead of print]). 61
32739182 2020
36
IgG4-related ophthalmic disease mimicking intraocular lymphoma: a case report. 61
33181803 2020
37
Case report of post streptococcal multifocal choroiditis in a young pregnant female: A success story. 61
33196327 2020
38
Imaging in Tubercular Choroiditis: Current Concepts. 61
32976732 2020
39
Optical coherence tomography angiography of choroidal neovascularization in immune choroiditis following acute retinal necrosis. 61
33246374 2020
40
Focal Scleral Nodule: A New Name for Solitary Idiopathic Choroiditis and Unifocal Helioid Choroiditis. 61
32507351 2020
41
Visual loss after long-haul flight. 61
33070639 2020
42
Choriocapillaris Involvement in Acute Syphilis Posterior Placoid Chorioretinitis is Responsible for Functional Impairment and Points towards an Immunologic Mechanism: A Comprehensive Clinicopathological Approach. 61
33553841 2020
43
Inflammatory choroiditis and papillitis from Crohn's disease in a child. 61
33127473 2020
44
Vogt-Koyanagi-Harada is a Curable Autoimmune Disease: Early Diagnosis and Immediate Dual Steroidal and Non-Steroidal Immunosuppression are Crucial Prerequisites. 61
33553831 2020
45
Lyme disease atypically presenting with a singular symptom: Unilateral chorioretinitis. 61
32998513 2020
46
Exudative Retinal Detachment in Ocular Inflammatory Diseases: Risk and Predictive Factors. 61
32621891 2020
47
Rapid and spontaneous resolution of hemorrhagic macular hole retinal detachment and subretinal hemorrhages in an eye with pathologic myopia: a case report. 61
32993567 2020
48
Sympathetic Ophthalmia - a Contribution to Immunology, Clinic and Current Imaging. 61
32967030 2020
49
Ocular manifestations of Blau syndrome. 61
32897920 2020
50
Lichen planus and multifocal choroiditis - A diagnostic dilemma. 61
32823424 2020

Variations for Choroiditis

Expression for Choroiditis

Search GEO for disease gene expression data for Choroiditis.

Pathways for Choroiditis

Pathways related to Choroiditis according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.22 VEGFA TNF NOD2 IL17A IL10 IFNG
2
Show member pathways
12.62 VEGFA TNF IL17A IL10 IFNG CD4
3
Show member pathways
12.45 TNF IL17A IL10 IFNG CD4
4 12.43 TNF IL17A IL10 IFNG
5
Show member pathways
12.43 TNF IL17A IL10 IFNG CD4
6
Show member pathways
12.27 TNF NOD2 IL17A IL10 IFNG CD4
7
Show member pathways
12.13 TNF IL17A IL10 IFNG
8 12.11 TNF NOD2 IL10 IFNG
9 11.82 TNF IL10 IFNG CD4
10 11.79 TNF IL10 IFNG
11 11.79 VEGFA TNF IL17A IL10
12 11.76 IL10 CFH CFB
13
Show member pathways
11.73 IL17A IFNG CD4
14 11.64 VEGFA TNF IL17A IFNG
15
Show member pathways
11.56 VEGFA TNF IFNG
16 11.49 TNF IL10 IFNG CD4
17 11.45 TNF IL10 IFNG
18 11.39 IL10 IFNG CD4
19 11.28 TNF IL10 IFNG
20
Show member pathways
11.26 TNF IL10 IFNG
21 11.26 TNF IL17A IL10 IFNG CD4
22 11.16 TNF IL17A IFNG
23 10.92 TNF IL10 IFNG CD4
24
Show member pathways
10.9 TNF IL17A IL10 IFNG CD4

GO Terms for Choroiditis

Cellular components related to Choroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 VEGFA TNF RBP3 IL17A IL10 IFNG
2 extracellular space GO:0005615 9.32 VEGFA TNF RBP3 IL17A IL10 IFNG

Biological processes related to Choroiditis according to GeneCards Suite gene sharing:

(show all 39)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 10.01 TNF IL17A IL10 IFNG CD4
2 negative regulation of gene expression GO:0010629 9.95 VEGFA TNF IFNG ACE
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.9 VEGFA TNF NOD2 CD4
4 positive regulation of protein phosphorylation GO:0001934 9.87 VEGFA TNF IFNG CD4
5 positive regulation of MAPK cascade GO:0043410 9.85 VEGFA NOD2 CD4
6 defense response to Gram-positive bacterium GO:0050830 9.83 TNF NOD2 IL17A
7 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.82 VEGFA NOD2 CD4
8 positive regulation of tumor necrosis factor production GO:0032760 9.81 NOD2 IL17A IFNG
9 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.8 VEGFA TNF IFNG
10 positive regulation of epithelial cell proliferation GO:0050679 9.78 VEGFA NOD2 HTRA1
11 cytokine-mediated signaling pathway GO:0019221 9.77 VEGFA TNF IL17A IL10 CD4
12 positive regulation of MAP kinase activity GO:0043406 9.75 VEGFA TNF NOD2
13 positive regulation of protein complex assembly GO:0031334 9.73 VEGFA TNF IFNG
14 positive regulation of cytokine production GO:0001819 9.72 TNF IL10 IFNG
15 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.68 NOD2 IFNG
16 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.67 TNF IFNG
17 astrocyte activation GO:0048143 9.67 TNF IFNG
18 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.67 TNF IL10
19 positive regulation of phagocytosis GO:0050766 9.67 TNF NOD2 IFNG
20 complement activation, alternative pathway GO:0006957 9.66 CFH CFB
21 positive regulation of signaling receptor activity GO:2000273 9.65 IL10 IFNG
22 positive regulation of interleukin-12 production GO:0032735 9.65 NOD2 IL17A IFNG
23 negative regulation of amyloid-beta clearance GO:1900222 9.64 TNF IFNG
24 positive regulation of MHC class II biosynthetic process GO:0045348 9.64 IL10 IFNG
25 endothelial cell apoptotic process GO:0072577 9.63 TNF IL10
26 regulation of complement-dependent cytotoxicity GO:1903659 9.62 IL10 CFH
27 positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 9.59 TNF NOD2
28 negative regulation of cytokine production involved in immune response GO:0002719 9.58 TNF IL10
29 positive regulation of peptidyl-tyrosine autophosphorylation GO:1900086 9.54 VEGFA ACE
30 positive regulation of interleukin-23 production GO:0032747 9.52 IL17A IFNG
31 negative regulation of interleukin-18 production GO:0032701 9.51 NOD2 IL10
32 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.5 TNF NOD2 IL17A
33 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.46 TNF IFNG
34 positive regulation of vitamin D biosynthetic process GO:0060557 9.43 TNF IFNG
35 positive regulation of osteoclast differentiation GO:0045672 9.43 TNF IL17A IFNG
36 positive regulation of nitrogen compound metabolic process GO:0051173 9.4 TNF IFNG
37 macrophage differentiation GO:0030225 9.33 VEGFA IFNG CD4
38 positive regulation of interleukin-6 production GO:0032755 9.26 TNF NOD2 IL17A IFNG
39 positive regulation of interleukin-1 beta production GO:0032731 8.92 TNF NOD2 IL17A IFNG

Molecular functions related to Choroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 VEGFA TNF IL17A IL10 IFNG

Sources for Choroiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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