MCID: CHR082
MIFTS: 23

Chromophil Adenoma of the Kidney

Categories: Cancer diseases

Aliases & Classifications for Chromophil Adenoma of the Kidney

MalaCards integrated aliases for Chromophil Adenoma of the Kidney:

Name: Chromophil Adenoma of the Kidney 12 15
Papillary Adenoma of the Kidney 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6257
NCIt 49 C3687
UMLS 71 C1518879

Summaries for Chromophil Adenoma of the Kidney

MalaCards based summary : Chromophil Adenoma of the Kidney, also known as papillary adenoma of the kidney, is related to papillary adenoma and renal cell carcinoma, papillary, 1. An important gene associated with Chromophil Adenoma of the Kidney is PRCC (Proline Rich Mitotic Checkpoint Control Factor), and among its related pathways/superpathways are Transcription_NF-kB signaling pathway and Cellular Transformation by HTLV1. Affiliated tissues include kidney, breast and prostate, and related phenotypes are liver/biliary system and renal/urinary system

Related Diseases for Chromophil Adenoma of the Kidney

Diseases related to Chromophil Adenoma of the Kidney via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 85)
# Related Disease Score Top Affiliating Genes
1 papillary adenoma 30.0 TFE3 PRCC KRT7 AMACR
2 renal cell carcinoma, papillary, 1 28.0 TFE3 PRCC PBRM1 MME KRT7 AMACR
3 renal cell carcinoma, nonpapillary 27.9 TFE3 PRCC PBRM1 MME KRT7 AMACR
4 type 1 papillary adenoma of the kidney 12.5
5 type 2 papillary adenoma of the kidney 12.5
6 renal cell carcinoma, xp11-associated 10.4 TFE3 PRCC
7 childhood kidney cell carcinoma 10.3 TFE3 PRCC
8 adenoma 10.3
9 endometrial transitional cell carcinoma 10.3 SMIM20 KRT7
10 ureteral benign neoplasm 10.2 SMIM20 KRT7
11 clear cell adenocarcinoma 10.2 KRT7 AMACR
12 nephrogenic adenoma 10.2 KRT7 AMACR
13 urethral diverticulum 10.1 KRT7 AMACR
14 epithelioid sarcoma 10.1 PBRM1 KRT7
15 bladder adenocarcinoma 10.1 KRT7 AMACR
16 ovarian mucinous adenocarcinoma 10.0 KRT7 AMACR
17 urethra clear cell adenocarcinoma 10.0 KRT7 AMACR
18 chromophil renal cell carcinoma 9.9
19 macrophage activation syndrome 9.9 TNFRSF1B TNFRSF1A
20 metanephric adenoma 9.9 PRCC KRT7 AMACR
21 post-transplant lymphoproliferative disease 9.9 TNFRSF1B TNFRSF1A
22 subareolar duct papillomatosis 9.9 MME KRT7
23 nipple neoplasm 9.9 MME KRT7
24 mixed epithelial stromal tumour 9.9 MME KRT7
25 cervical adenoma malignum 9.9 MME KRT7
26 epididymal neoplasm 9.9 MME KRT7
27 ovarian wilms' cancer 9.9 MME KRT7
28 eccrine papillary adenocarcinoma 9.9 MME KRT7
29 clear cell hidradenoma 9.9 MME KRT7
30 hidradenoma 9.9 MME KRT7
31 wolffian duct adenocarcinoma 9.9 MME KRT7
32 cystadenofibroma 9.9 MME KRT7
33 palindromic rheumatism 9.9 TNFRSF1B TNFRSF1A
34 adenofibroma 9.9 MME KRT7
35 eccrine sweat gland neoplasm 9.9 MME KRT7
36 sweat gland neoplasm 9.9 MME KRT7
37 balloon cell malignant melanoma 9.9 MME KRT7
38 pancreatic mucinous cystadenoma 9.9 MME KRT7
39 epididymis adenocarcinoma 9.9 MME KRT7
40 epididymis cancer 9.8 MME KRT7
41 pulmonary artery leiomyosarcoma 9.8 MME KRT7
42 nasal cavity olfactory neuroblastoma 9.8 MME KRT7
43 cutaneous adenocystic carcinoma 9.8 MME KRT7
44 ovarian sex-cord stromal tumor 9.8 MME KRT7
45 cervical mucinous adenocarcinoma 9.8 MME KRT7
46 prostate lymphoma 9.8 MME AMACR
47 adenomyoma 9.8 MME KRT7
48 perivascular epithelioid cell tumor 9.8 TFE3 MME
49 breast osteosarcoma 9.8 MME KRT7
50 squamous papillomatosis 9.8 MME KRT7

Graphical network of the top 20 diseases related to Chromophil Adenoma of the Kidney:



Diseases related to Chromophil Adenoma of the Kidney

Symptoms & Phenotypes for Chromophil Adenoma of the Kidney

MGI Mouse Phenotypes related to Chromophil Adenoma of the Kidney:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.35 AMACR MME PBRM1 TNFRSF1A TNFRSF1B
2 renal/urinary system MP:0005367 9.02 KRT7 PBRM1 PTCH2 TNFRSF1A TNFRSF1B

Drugs & Therapeutics for Chromophil Adenoma of the Kidney

Search Clinical Trials , NIH Clinical Center for Chromophil Adenoma of the Kidney

Genetic Tests for Chromophil Adenoma of the Kidney

Anatomical Context for Chromophil Adenoma of the Kidney

MalaCards organs/tissues related to Chromophil Adenoma of the Kidney:

40
Kidney, Breast, Prostate

Publications for Chromophil Adenoma of the Kidney

Articles related to Chromophil Adenoma of the Kidney:

# Title Authors PMID Year
1
Papillary adenoma of the kidney with mucinous secretion. 61
11332693 2001
2
[Tubular and papillary adenoma of the kidney]. 61
5533650 1970
3
[Papillary adenoma of the kidney]. 61
14841752 1951
4
[Papillary adenoma of the kidney]. 61
14774383 1950
5
II. Malignant Papillary Adenoma of the Kidney. 61
17862757 1911

Variations for Chromophil Adenoma of the Kidney

Expression for Chromophil Adenoma of the Kidney

Search GEO for disease gene expression data for Chromophil Adenoma of the Kidney.

Pathways for Chromophil Adenoma of the Kidney

Pathways related to Chromophil Adenoma of the Kidney according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.1 TNFRSF1B TNFRSF1A
2
Show member pathways
11.02 TNFRSF1B TNFRSF1A
3 10.95 TNFRSF1B TNFRSF1A
4 10.67 TNFRSF1B TNFRSF1A
5 10.46 TNFRSF1B TNFRSF1A
6 10.1 TNFRSF1B TNFRSF1A

GO Terms for Chromophil Adenoma of the Kidney

Cellular components related to Chromophil Adenoma of the Kidney according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 9.13 TNFRSF1B TNFRSF1A MME
2 tumor necrosis factor receptor superfamily complex GO:0002947 8.62 TNFRSF1B TNFRSF1A

Biological processes related to Chromophil Adenoma of the Kidney according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.37 TNFRSF1B TNFRSF1A
2 negative regulation of cardiac muscle hypertrophy GO:0010614 9.32 TNFRSF1B TNFRSF1A
3 aortic valve development GO:0003176 9.26 TNFRSF1B TNFRSF1A
4 negative regulation of extracellular matrix constituent secretion GO:0003332 9.16 TNFRSF1B TNFRSF1A
5 pulmonary valve development GO:0003177 8.96 TNFRSF1B TNFRSF1A
6 positive regulation of apoptotic process involved in morphogenesis GO:1902339 8.62 TNFRSF1B TNFRSF1A

Molecular functions related to Chromophil Adenoma of the Kidney according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-activated receptor activity GO:0005031 8.96 TNFRSF1B TNFRSF1A
2 tumor necrosis factor binding GO:0043120 8.62 TNFRSF1B TNFRSF1A

Sources for Chromophil Adenoma of the Kidney

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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