MCID: CHR082
MIFTS: 25

Chromophil Adenoma of the Kidney

Categories: Cancer diseases

Aliases & Classifications for Chromophil Adenoma of the Kidney

MalaCards integrated aliases for Chromophil Adenoma of the Kidney:

Name: Chromophil Adenoma of the Kidney 12 15
Papillary Adenoma of the Kidney 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6257
NCIt 49 C3687
UMLS 71 C1518879

Summaries for Chromophil Adenoma of the Kidney

MalaCards based summary : Chromophil Adenoma of the Kidney, also known as papillary adenoma of the kidney, is related to papillary adenoma and renal cell carcinoma, papillary, 1. An important gene associated with Chromophil Adenoma of the Kidney is PRCC (Proline Rich Mitotic Checkpoint Control Factor), and among its related pathways/superpathways are Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions and TNF signaling. Affiliated tissues include kidney, and related phenotypes are integument and liver/biliary system

Related Diseases for Chromophil Adenoma of the Kidney

Diseases related to Chromophil Adenoma of the Kidney via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 papillary adenoma 30.2 TFE3 PRCC KRT7 AMACR
2 renal cell carcinoma, papillary, 1 28.3 TFE3 PRCC PBRM1 MME KRT7 AMACR
3 renal cell carcinoma, nonpapillary 28.3 TFE3 PRCC PBRM1 MME KRT7 AMACR
4 type 1 papillary adenoma of the kidney 12.6
5 type 2 papillary adenoma of the kidney 12.6
6 renal cell carcinoma, xp11-associated 10.4 TFE3 PRCC
7 childhood kidney cell carcinoma 10.4 TFE3 PRCC
8 familial renal papillary carcinoma 10.4 TFE3 PRCC
9 nephrogenic adenofibroma 10.4 TFE3 KRT7
10 renal pelvis carcinoma 10.4 PRCC KRT7
11 kidney angiomyolipoma 10.4 TFE3 PRCC
12 ureteral benign neoplasm 10.4 SMIM20 KRT7
13 nephrogenic adenoma 10.3 KRT7 AMACR
14 adenoma 10.3
15 seminal vesicle adenocarcinoma 10.3 KRT7 AMACR
16 bladder benign neoplasm 10.3 KRT7 AMACR
17 urethral diverticulum 10.3 KRT7 AMACR
18 glandular cystitis 10.3 KRT7 AMACR
19 bladder adenocarcinoma 10.2 KRT7 AMACR
20 ovarian mucinous adenocarcinoma 10.2 KRT7 AMACR
21 birt-hogg-dube syndrome 10.2 TFE3 PRCC
22 epithelial predominant wilms' tumor 10.1 PRCC KRT7 AMACR
23 perivascular epithelioid cell tumor 10.0 TFE3 MME
24 hereditary periodic fever syndrome 10.0 TNFRSF1A TNF
25 juvenile ankylosing spondylitis 10.0 TNFRSF1B TNF
26 rheumatoid arthritis interstitial lung disease 10.0 TNFRSF1B TNF
27 dystrophinopathies 10.0 TNFRSF1A TNF
28 intestinal perforation 10.0 TNF KRT7
29 skin sarcoidosis 10.0 TNFRSF1B TNF
30 subareolar duct papillomatosis 10.0 MME KRT7
31 necrobiosis lipoidica 10.0 TNFRSF1B TNF
32 nipple benign neoplasm 10.0 MME KRT7
33 adenofibroma 10.0 MME KRT7
34 opportunistic bacterial infectious disease 10.0 TNFRSF1B TNF
35 pancreatic serous cystadenocarcinoma 10.0 MME KRT7
36 mixed epithelial stromal tumour 10.0 MME KRT7
37 epididymal neoplasm 10.0 MME KRT7
38 nocardiosis 10.0 TNFRSF1B TNF
39 granulomatous hepatitis 10.0 TNFRSF1B TNF
40 clear cell hidradenoma 10.0 MME KRT7
41 hidradenoma 10.0 MME KRT7
42 granuloma annulare 10.0 TNFRSF1B TNF
43 wolffian duct adenocarcinoma 10.0 MME KRT7
44 spondylarthropathy 10.0 TNFRSF1A TNF
45 pulmonary artery leiomyosarcoma 10.0 MME KRT7
46 mononeuritis of upper limb and mononeuritis multiplex 10.0 TNFRSF1B TNF
47 balloon cell malignant melanoma 10.0 MME KRT7
48 mononeuritis multiplex 10.0 TNFRSF1B TNF
49 granulomatous dermatitis 10.0 TNFRSF1B TNF
50 pancreatic mucinous cystadenoma 10.0 MME KRT7

Graphical network of the top 20 diseases related to Chromophil Adenoma of the Kidney:



Diseases related to Chromophil Adenoma of the Kidney

Symptoms & Phenotypes for Chromophil Adenoma of the Kidney

MGI Mouse Phenotypes related to Chromophil Adenoma of the Kidney:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.43 MME PTCH2 TFE3 TNF TNFRSF1A TNFRSF1B
2 liver/biliary system MP:0005370 9.1 AMACR MME PBRM1 TNF TNFRSF1A TNFRSF1B

Drugs & Therapeutics for Chromophil Adenoma of the Kidney

Search Clinical Trials , NIH Clinical Center for Chromophil Adenoma of the Kidney

Genetic Tests for Chromophil Adenoma of the Kidney

Anatomical Context for Chromophil Adenoma of the Kidney

MalaCards organs/tissues related to Chromophil Adenoma of the Kidney:

40
Kidney

Publications for Chromophil Adenoma of the Kidney

Articles related to Chromophil Adenoma of the Kidney:

# Title Authors PMID Year
1
Papillary adenoma of the kidney with mucinous secretion. 61
11332693 2001
2
[Tubular and papillary adenoma of the kidney]. 61
5533650 1970
3
[Papillary adenoma of the kidney]. 61
14841752 1951
4
[Papillary adenoma of the kidney]. 61
14774383 1950
5
II. Malignant Papillary Adenoma of the Kidney. 61
17862757 1911

Variations for Chromophil Adenoma of the Kidney

Expression for Chromophil Adenoma of the Kidney

Search GEO for disease gene expression data for Chromophil Adenoma of the Kidney.

Pathways for Chromophil Adenoma of the Kidney

Pathways related to Chromophil Adenoma of the Kidney according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.07 TNFRSF1B TNFRSF1A TNF
2
Show member pathways
12.04 TNFRSF1B TNFRSF1A TNF
3 11.97 TNFRSF1B TNFRSF1A TNF
4 11.84 TNFRSF1A TNF MME
5 11.7 TNFRSF1B TNFRSF1A TNF
6 11.61 TNFRSF1B TNFRSF1A TNF
7
Show member pathways
11.52 TNFRSF1B TNFRSF1A TNF
8
Show member pathways
11.44 TNFRSF1B TNFRSF1A TNF
9 11.38 TNFRSF1B TNFRSF1A TNF
10 11.23 TNFRSF1B TNFRSF1A TNF
11
Show member pathways
11.14 TNFRSF1B TNFRSF1A TNF
12 11.07 TNFRSF1B TNFRSF1A
13 11.02 TNFRSF1B TNFRSF1A TNF
14 10.87 TNFRSF1A TNF
15
Show member pathways
10.69 TNFRSF1B TNFRSF1A TNF
16 10.3 TNFRSF1B TNFRSF1A TNF

GO Terms for Chromophil Adenoma of the Kidney

Cellular components related to Chromophil Adenoma of the Kidney according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 9.26 TNFRSF1B TNFRSF1A TNF MME
2 tumor necrosis factor receptor superfamily complex GO:0002947 8.62 TNFRSF1B TNFRSF1A

Biological processes related to Chromophil Adenoma of the Kidney according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-mediated signaling pathway GO:0033209 9.63 TNFRSF1B TNFRSF1A TNF
2 extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 9.54 TNFRSF1A TNF
3 regulation of tumor necrosis factor-mediated signaling pathway GO:0010803 9.52 TNFRSF1A TNF
4 negative regulation of cardiac muscle hypertrophy GO:0010614 9.51 TNFRSF1B TNFRSF1A
5 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.49 TNFRSF1B TNF
6 regulation of osteoclast differentiation GO:0045670 9.48 TNF TFE3
7 positive regulation of ceramide biosynthetic process GO:2000304 9.43 TNFRSF1A TNF
8 regulation of establishment of endothelial barrier GO:1903140 9.4 TNFRSF1A TNF
9 death-inducing signaling complex assembly GO:0071550 9.37 TNFRSF1A TNF
10 aortic valve development GO:0003176 9.32 TNFRSF1B TNFRSF1A
11 negative regulation of extracellular matrix constituent secretion GO:0003332 9.26 TNFRSF1B TNFRSF1A
12 pulmonary valve development GO:0003177 9.16 TNFRSF1B TNFRSF1A
13 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.13 TNFRSF1B TNFRSF1A TNF
14 positive regulation of apoptotic process involved in morphogenesis GO:1902339 8.62 TNFRSF1B TNFRSF1A

Molecular functions related to Chromophil Adenoma of the Kidney according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-activated receptor activity GO:0005031 8.96 TNFRSF1B TNFRSF1A
2 tumor necrosis factor binding GO:0043120 8.62 TNFRSF1B TNFRSF1A

Sources for Chromophil Adenoma of the Kidney

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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