MCID: CHR181
MIFTS: 11

Chromosome 10p Deletion

Categories: Rare diseases

Aliases & Classifications for Chromosome 10p Deletion

MalaCards integrated aliases for Chromosome 10p Deletion:

Name: Chromosome 10p Deletion 53
Chromosome 10, Monosomy 10p 73
Partial Monosomy 10p 53
10p Deletion 53
10p Monosomy 53
Deletion 10p 53
Monosomy 10p 53

Classifications:



External Ids:

UMLS 73 C0795836

Summaries for Chromosome 10p Deletion

NIH Rare Diseases : 53 Chromosome 10p deletion is a chromosome abnormality that occurs when there is a missing (deleted) copy of genetic material on the short arm (p) of  chromosome 10. The severity and the signs and symptoms depend on the size and location of the deletion and which genes are involved. Features may affect many parts of the body and may include low birth weight, growth delay, developmental delay, low muscle tone (hypotonia), and communication difficulties. Birth defects, various medical problems, and/or distinctive facial features may also be present. Most 10p deletions are not inherited and occur randomly during the formation of egg or sperm cells, or very early in fetal development. Some 10p deletions are present because a parent has a rearrangement of genetic material on his/her chromosomes. This rearrangement is usually a balanced translocation, which typically does not cause any health problems. In some cases, a parent has the same deletion as the child. Chromosome testing of both parents can provide information about whether the deletion was inherited. Treatment for chromosome 10p deletion is based on the signs and symptoms in each person. This page is meant to provide general information about 10p deletions. You can contact GARD if you have questions about a specific deletion on chromosome 10p. To learn more about chromosome abnormalities, please visit our GARD webpage on FAQs about Chromosome Disorders.

MalaCards based summary : Chromosome 10p Deletion, also known as chromosome 10, monosomy 10p, is related to digeorge syndrome/velocardiofacial syndrome complex 2 and digeorge syndrome. Affiliated tissues include testes.

Related Diseases for Chromosome 10p Deletion

Diseases related to Chromosome 10p Deletion via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 digeorge syndrome/velocardiofacial syndrome complex 2 11.2
2 digeorge syndrome 10.1
3 choanal atresia, posterior 10.1
4 chromosomal triplication 10.1
5 chromosome 10p duplication 10.1
6 autism 10.0
7 hypoparathyroidism 10.0

Graphical network of the top 20 diseases related to Chromosome 10p Deletion:



Diseases related to Chromosome 10p Deletion

Symptoms & Phenotypes for Chromosome 10p Deletion

Drugs & Therapeutics for Chromosome 10p Deletion

Search Clinical Trials , NIH Clinical Center for Chromosome 10p Deletion

Genetic Tests for Chromosome 10p Deletion

Anatomical Context for Chromosome 10p Deletion

MalaCards organs/tissues related to Chromosome 10p Deletion:

41
Testes

Publications for Chromosome 10p Deletion

Articles related to Chromosome 10p Deletion:

# Title Authors Year
1
Chromosome 10p deletion in a patient with hypoparathyroidism, severe mental retardation, autism and basal ganglia calcifications. ( 15337474 )
2004

Variations for Chromosome 10p Deletion

Expression for Chromosome 10p Deletion

Search GEO for disease gene expression data for Chromosome 10p Deletion.

Pathways for Chromosome 10p Deletion

GO Terms for Chromosome 10p Deletion

Sources for Chromosome 10p Deletion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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