MCID: CHR264
MIFTS: 15

Chromosome 8p Deletion

Categories: Rare diseases

Aliases & Classifications for Chromosome 8p Deletion

MalaCards integrated aliases for Chromosome 8p Deletion:

Name: Chromosome 8p Deletion 53
Chromosome 8, Monosomy 8p 72
Partial Monosomy 8p 53
8p Deletion 53
8p Monosomy 53
Deletion 8p 53
Monosomy 8p 53

Classifications:



External Ids:

UMLS 72 C0795824

Summaries for Chromosome 8p Deletion

NIH Rare Diseases : 53 Chromosome 8p deletion is a chromosome abnormality that affects many different parts of the body. People with this condition are missing genetic material located on the short arm (p) of chromosome 8 in each cell. The severity of the condition and the associated signs and symptoms vary based on the size and location of the deletion and which genes are involved. Most cases are not inherited, although affected people can pass the deletion on to their children. Treatment is based on the signs and symptoms present in each person.

MalaCards based summary : Chromosome 8p Deletion, also known as chromosome 8, monosomy 8p, is related to 8p inverted duplication/deletion syndrome and chromosome 13q duplication. An important gene associated with Chromosome 8p Deletion is NKX3-1 (NK3 Homeobox 1). Affiliated tissues include prostate and heart.

Related Diseases for Chromosome 8p Deletion

Graphical network of the top 20 diseases related to Chromosome 8p Deletion:



Diseases related to Chromosome 8p Deletion

Symptoms & Phenotypes for Chromosome 8p Deletion

Drugs & Therapeutics for Chromosome 8p Deletion

Search Clinical Trials , NIH Clinical Center for Chromosome 8p Deletion

Genetic Tests for Chromosome 8p Deletion

Anatomical Context for Chromosome 8p Deletion

MalaCards organs/tissues related to Chromosome 8p Deletion:

41
Prostate, Heart

Publications for Chromosome 8p Deletion

Articles related to Chromosome 8p Deletion:

(show all 21)
# Title Authors PMID Year
1
Partial monosomy 8p and trisomy 16q in two children with developmental delay detected by array comparative genomic hybridization. 38
29039589 2017
2
De novo case of a partial trisomy 4p and a partial monosomy 8p. 38
24851635 2014
3
[Paternally originated Wolf-Hirschhorn syndrome detected by multiplex ligation-dependent probe amplification and microarray comparative genomic hybridization]. 38
22931946 2012
4
Partial monosomy 8p/trisomy 8q in a newborn infant due to a maternal three-way translocation: Clinical and cytogenetic comparison with San Luis Valley syndrome. 38
20635365 2010
5
Loss of heterozygosity at D8S298 is a predictor for long-term survival of patients with tumor-node-metastasis stage I of hepatocellular carcinoma. 38
18094418 2007
6
Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: association with gleason score and chromosome 8p deletion. 38
17108105 2006
7
The prognostic value of circulating plasma DNA level and its allelic imbalance on chromosome 8p in patients with hepatocellular carcinoma. 38
16502316 2006
8
HTPAP gene on chromosome 8p is a candidate metastasis suppressor for human hepatocellular carcinoma. 38
16261160 2006
9
Prenatal diagnosis of de novo partial trisomy 13q (13q22 --> qter) and partial monosomy 8p (8p23.3 --> pter) associated with holoprosencephaly, premaxillary agenesis, hexadactyly, and a hypoplastic left heart. 38
15849788 2005
10
A decade's studies on metastasis of hepatocellular carcinoma. 38
14685850 2004
11
Identification of the prostate cancer micro-foci with chromosome 8p deletion at the tumor interface area by histopathological-FISH parallel examination. 38
11713582 2001
12
Chromosome 8p deletion is associated with metastasis of human hepatocellular carcinoma when high and low metastatic models are compared. 38
11501747 2001
13
Three-year-old girl with partial trisomy 4p and partial monosomy 8p with resemblance to Brachmann-de Lange syndrome--another locus for Brachmann-de Lange syndrome on 4p? 38
10756338 2000
14
The association of chromosome 8p deletion and tumor metastasis in human hepatocellular carcinoma. 38
10582679 1999
15
Follow-up of a patient with partial trisomy 9p and partial monosomy 8p; description of physical and psychosocial development. 38
8652090 1996
16
Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer. 38
7689419 1993
17
Partial monosomy 8p and partial trisomy 8p with moderate mental retardation. 38
1642815 1992
18
Partial monosomy 8p with minimal dysmorphic signs. 38
2352261 1990
19
Unbalanced karyotype with normal phenotype in a family with translocation (8;13)(p21;q22). 38
4006274 1985
20
New chromosomal malformation syndromes. I. Partial monosomy 8p. An attempt to establish a new chromosome deletion syndrome. 38
870324 1977
21
[Partial deletion of the short arm of chromosome 8]. 38
302680 1977

Variations for Chromosome 8p Deletion

Expression for Chromosome 8p Deletion

Search GEO for disease gene expression data for Chromosome 8p Deletion.

Pathways for Chromosome 8p Deletion

GO Terms for Chromosome 8p Deletion

Sources for Chromosome 8p Deletion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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