MCID: CHR463
MIFTS: 35

Chronic Actinic Dermatitis

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Chronic Actinic Dermatitis

MalaCards integrated aliases for Chronic Actinic Dermatitis:

Name: Chronic Actinic Dermatitis 59 73
Actinic Reticuloid 59 73
Chronic Photosensitivity Dermatitis 59

Characteristics:

Orphanet epidemiological data:

59
chronic actinic dermatitis
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 59  
Rare skin diseases


External Ids:

Orphanet 59 ORPHA330064
UMLS via Orphanet 74 C1510437 C0282309
ICD10 33 L57.1

Summaries for Chronic Actinic Dermatitis

MalaCards based summary : Chronic Actinic Dermatitis, also known as actinic reticuloid, is related to dermatitis and dermatitis, atopic. An important gene associated with Chronic Actinic Dermatitis is CCR7 (C-C Motif Chemokine Receptor 7), and among its related pathways/superpathways are Integrin Pathway and Degradation of the extracellular matrix. Affiliated tissues include skin, t cells and testes.

Wikipedia : 76 Chronic actinic dermatitis (also known as "Actinic reticuloid," "Chronic photosensitivity dermatitis,"... more...

Related Diseases for Chronic Actinic Dermatitis

Diseases related to Chronic Actinic Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 dermatitis 10.9
2 dermatitis, atopic 10.3
3 mycosis fungoides 10.2
4 sezary's disease 10.2
5 psoriasis 10.2
6 lymphoma 10.1
7 cutaneous t cell lymphoma 10.1
8 senile ectropion 10.1 ELN MMP9
9 cerebral arterial disease 10.1 ELN MMP9
10 aortic aneurysm 10.1 ELN FBN1
11 hidradenitis 10.1
12 cutaneous pseudolymphoma 10.1
13 pseudoxanthoma elasticum 10.1 ELN FBN1
14 pseudoxanthoma elasticum-like papillary dermal elastolysis 10.1 ELN FBN1
15 late-onset focal dermal elastosis 10.1 ELN FBN1
16 familial abdominal aortic aneurysm 10.1 ELN FBN1
17 mid-dermal elastolysis 10.0 ELN FBN1
18 autosomal recessive cutis laxa type iii 10.0 ELN FBN1
19 phacogenic glaucoma 10.0 ELN FBN1
20 supravalvular aortic stenosis 10.0 ELN FBN1
21 adult t-cell leukemia 10.0
22 leukemia 10.0
23 contact dermatitis 10.0
24 t-cell leukemia 10.0
25 viral infectious disease 10.0
26 aortic valve insufficiency 10.0 ELN FBN1
27 sorsby fundus dystrophy 10.0 ELN FBN1
28 cutis laxa, autosomal dominant 1 10.0 ELN FBN1
29 heart valve disease 10.0 ELN FBN1
30 cholesteatoma of middle ear 10.0 FLG MMP9
31 lipoid proteinosis of urbach and wiethe 10.0 FBN1 MMP9
32 marfan syndrome 10.0 ELN FBN1
33 orthostatic intolerance 10.0 ELN FBN1
34 spastic entropion 10.0 MMP1 MMP9
35 epidermolysis bullosa pruriginosa 9.9 FLG MMP1
36 internal hemorrhoid 9.9 MMP1 MMP9
37 chromoblastomycosis 9.9 MMP1 MMP9
38 light chain deposition disease 9.9 MMP1 MMP9
39 adult astrocytic tumour 9.9 MMP1 MMP9
40 odontogenic myxoma 9.9 MMP1 MMP9
41 collagenous colitis 9.9 MMP1 MMP9
42 chronic venous insufficiency 9.9 MMP1 MMP9
43 venous insufficiency 9.9 MMP1 MMP9
44 recessive dystrophic epidermolysis bullosa 9.9 FLG MMP1
45 aortic valve disease 1 9.9 ELN FBN1
46 hypertensive heart disease 9.9 MMP1 MMP9
47 preterm premature rupture of the membranes 9.9 MMP1 MMP9
48 carotid stenosis 9.9 MMP1 MMP9
49 carotid artery disease 9.9 MMP1 MMP9
50 lymphangioleiomyomatosis 9.9 ELN MMP1

Graphical network of the top 20 diseases related to Chronic Actinic Dermatitis:



Diseases related to Chronic Actinic Dermatitis

Symptoms & Phenotypes for Chronic Actinic Dermatitis

Drugs & Therapeutics for Chronic Actinic Dermatitis

Search Clinical Trials , NIH Clinical Center for Chronic Actinic Dermatitis

Genetic Tests for Chronic Actinic Dermatitis

Anatomical Context for Chronic Actinic Dermatitis

MalaCards organs/tissues related to Chronic Actinic Dermatitis:

41
Skin, T Cells, Testes, Heart, Neutrophil

Publications for Chronic Actinic Dermatitis

Articles related to Chronic Actinic Dermatitis:

(show top 50) (show all 193)
# Title Authors Year
1
Increased incidence of chronic actinic dermatitis in relation to climate changes and air pollution during the past 15 years in Korea. ( 29889316 )
2018
2
Chronic actinic dermatitis. ( 29530872 )
2018
3
Evaluation of narrow band ultraviolet B phototherapy in the treatment of chronic actinic dermatitis in Chinese patients. ( 29047198 )
2017
4
Phenotypic analysis of circulating T-cell subset and its association with burden of skin disease in patients with chronic actinic dermatitis: a hematologic and clinicopathologic study of 20 subjects. ( 28176301 )
2017
5
Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis. ( 28050588 )
2017
6
Genome-Wide Analysis of mRNA and Long Noncoding RNA Profiles in Chronic Actinic Dermatitis. ( 29359156 )
2017
7
Chronic actinic dermatitis: successful treatment with PUVA photochemotherapy. ( 28889653 )
2017
8
Comparison of Demographic and Photobiological Features of Chronic Actinic Dermatitis in Patients With Lighter vs Darker Skin Types. ( 28329062 )
2017
9
Tacrolimus 0.1% ointment applied under occlusion using cling film clears chronic actinic dermatitis resistant to systemic treatment. ( 28239836 )
2017
10
The Clinical Severity Score of Chronic Actinic Dermatitis (CSS-CAD) Correlates with In Vivo Photoallergic Reactions and the Immunologic Parameters related to a Shift towards Th2 Immunity from the Th2/Th1 Balanced Status in Patients with Chronic Actinic Dermatitis. ( 27084788 )
2016
11
Tungsten lamp and chronic actinic dermatitis. ( 26299466 )
2015
12
Chronic actinic dermatitis occurring in an adult with atopic dermatitis. ( 26990344 )
2015
13
Is photodynamic diagnostic flexible ureterorenoscopy suitable for a patient presenting with chronic actinic dermatitis? ( 26012562 )
2015
14
Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis. ( 25734812 )
2015
15
Chronic actinic dermatitis. ( 24891057 )
2014
16
The natural history of chronic actinic dermatitis: an analysis at a single institution in the United States. ( 24407058 )
2014
17
Chronic actinic dermatitis/actinic reticuloid: a clinicopathologic and immunohistochemical analysis of 37 cases. ( 25238449 )
2014
18
A case of false-negative monochromator phototesting in a patient with chronic actinic dermatitis taking prednisolone. ( 22250731 )
2012
19
Actinic reticuloid imitating Sézary syndrome. ( 23267873 )
2012
20
Actinic reticuloid presented as facies leonine. ( 22250638 )
2012
21
A photosensitive pseudolymphomatous eruption. Actinic reticuloid (AR). ( 22340697 )
2012
22
Chronic actinic dermatitis with leonine facies and iatrogenic adrenal insufficiency successfully treated with topical tacrolimus. ( 21487461 )
2011
23
Chronic actinic dermatitis: two patients with successful management using narrowband ultraviolet B phototherapy with systemic steroids. ( 22031690 )
2011
24
Positive patch- and photopatch-test reactions to methylene bis-benzotriazolyl tetramethylbutylphenol in patients with both atopic dermatitis and chronic actinic dermatitis. ( 21504696 )
2011
25
Chronic actinic dermatitis: an analysis at a single institution over 25 years. ( 21569744 )
2011
26
Chronic actinic dermatitis in Asian skin: a Singaporean experience. ( 21729163 )
2011
27
Actinic reticuloid--photosensitivity or pseudolymphoma?--A review. ( 22220464 )
2011
28
False-negative monochromator phototesting in chronic actinic dermatitis. ( 20184579 )
2010
29
Treatment with topical tacrolimus favors chronic actinic dermatitis: a clinical and immunopathological study. ( 20394493 )
2010
30
Contact and photocontact sensitization in chronic actinic dermatitis: a changing picture. ( 20136878 )
2010
31
Chronic actinic dermatitis to sesquiterpene lactones: [2+2] photoreaction toward thymidine of (+) and (-) alpha-methylene-hexahydrobenzofuranone with a cis ring junction. ( 20113426 )
2010
32
Diagnosis and pharmacological treatment of chronic actinic dermatitis in the elderly: an update. ( 20524705 )
2010
33
The spontaneous resolution of photosensitivity and contact allergy in a patient with chronic actinic dermatitis. ( 19292791 )
2009
34
Case report of four patients with erythrodermic cutaneous T-cell lymphoma and severe photosensitivity mimicking chronic actinic dermatitis. ( 19067712 )
2009
35
Chronic actinic dermatitis: clinical cases, diagnostic workup, and therapeutic management. ( 19426619 )
2009
36
A Korean experience with chronic actinic dermatitis during an 18-year period: meteorological and photoimmunological aspects. ( 19906162 )
2009
37
Surgical management of chronic actinic dermatitis. ( 17765670 )
2008
38
[Expressions of fibrillin-1, elastin and matrix metalloproteinase-1 and -9 in chronic actinic dermatitis in elderly patients]. ( 18753059 )
2008
39
Chronic actinic dermatitis. ( 18627761 )
2008
40
Chronic actinic dermatitis in a patient with adult T-cell leukemia. ( 18477134 )
2008
41
Successful treatment of nodular actinic reticuloid with tacrolimus ointment. ( 16707890 )
2006
42
Recalcitrant chronic actinic dermatitis treated with low-dose thalidomide. ( 15858462 )
2005
43
A case of chronic actinic dermatitis treated with topical tacrolimus. ( 16249148 )
2005
44
Chronic actinic dermatitis treated with mycophenolate mofetil. ( 15840115 )
2005
45
Successful treatment of chronic actinic dermatitis with topical pimecrolimus. ( 15811093 )
2005
46
Chronic actinic dermatitis--a study of clinical features. ( 16394483 )
2005
47
Exacerbation of presumed chronic actinic dermatitis by cockpit visible light in an airline pilot with atopic eczema. ( 15888133 )
2005
48
Chronic actinic dermatitis recognized on minimal erythema dose testing prior to narrow-band UVB treatment for psoriasis. ( 15752132 )
2005
49
Chronic actinic dermatitis associated with adult T-cell leukemia. ( 15692511 )
2005
50
Chronic actinic dermatitis in the elderly: recognition and treatment. ( 15813653 )
2005

Variations for Chronic Actinic Dermatitis

Expression for Chronic Actinic Dermatitis

Search GEO for disease gene expression data for Chronic Actinic Dermatitis.

Pathways for Chronic Actinic Dermatitis

Pathways related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.79 CCR7 ELN FBN1 MMP1 MMP9
2
Show member pathways
12.11 ELN FBN1 MMP1 MMP9
3 11.58 MMP1 MMP9
4
Show member pathways
11.51 MMP1 MMP9
5 11.36 MMP1 MMP9
6
Show member pathways
11.34 ELN FBN1
7 11.26 ELN MMP9
8
Show member pathways
11.23 MMP1 MMP9
9 11.19 MMP1 MMP9
10
Show member pathways
11.12 CCR7 ELN FBN1 MMP1 MMP9
11 10.9 MMP1 MMP9
12 10.72 ELN MMP1 MMP9
13 10.55 MMP1 MMP9

GO Terms for Chronic Actinic Dermatitis

Cellular components related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 9.26 ELN FBN1 MMP1 MMP9
2 collagen-containing extracellular matrix GO:0062023 8.92 ELN FBN1 FLG MMP9

Biological processes related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix disassembly GO:0022617 9.16 MMP1 MMP9
2 collagen catabolic process GO:0030574 8.96 MMP1 MMP9
3 extracellular matrix organization GO:0030198 8.8 ELN FBN1 MMP9

Molecular functions related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metalloendopeptidase activity GO:0004222 9.16 MMP1 MMP9
2 endopeptidase activity GO:0004175 8.96 MMP1 MMP9
3 extracellular matrix constituent conferring elasticity GO:0030023 8.62 ELN FBN1

Sources for Chronic Actinic Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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