MCID: CHR463
MIFTS: 33

Chronic Actinic Dermatitis

Categories: Skin diseases, Rare diseases

Aliases & Classifications for Chronic Actinic Dermatitis

MalaCards integrated aliases for Chronic Actinic Dermatitis:

Name: Chronic Actinic Dermatitis 59 73
Actinic Reticuloid 59 73
Chronic Photosensitivity Dermatitis 59

Characteristics:

Orphanet epidemiological data:

59
chronic actinic dermatitis
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 59  
Rare skin diseases


External Ids:

Orphanet 59 ORPHA330064
UMLS via Orphanet 74 C1510437 C0282309
ICD10 33 L57.1

Summaries for Chronic Actinic Dermatitis

MalaCards based summary : Chronic Actinic Dermatitis, also known as actinic reticuloid, is related to dermatitis and pseudoxanthoma elasticum-like papillary dermal elastolysis. An important gene associated with Chronic Actinic Dermatitis is ELN (Elastin), and among its related pathways/superpathways are Integrin Pathway and Degradation of the extracellular matrix. Affiliated tissues include skin, t cells and testes.

Wikipedia : 76 Chronic actinic dermatitis (also known as \"Actinic reticuloid,\" \"Chronic photosensitivity... more...

Related Diseases for Chronic Actinic Dermatitis

Diseases related to Chronic Actinic Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 dermatitis 10.8
2 pseudoxanthoma elasticum-like papillary dermal elastolysis 10.4 ELN FBN1
3 late-onset focal dermal elastosis 10.4 ELN FBN1
4 familial abdominal aortic aneurysm 10.4 ELN FBN1
5 mid-dermal elastolysis 10.3 ELN FBN1
6 phacogenic glaucoma 10.3 ELN FBN1
7 aortic valve insufficiency 10.3 ELN FBN1
8 supravalvular aortic stenosis 10.3 ELN FBN1
9 collagen disease 10.2 ELN FBN1
10 aortic valve disease 1 10.2 ELN FBN1
11 orthostatic intolerance 10.2 ELN FBN1
12 dermatitis, atopic 10.2
13 marfan syndrome 10.2 ELN FBN1
14 lymphangioleiomyomatosis 10.2 ELN MMP1
15 aortic valve disease 2 10.1 ELN FBN1
16 mitral valve disease 10.1 FBN1 MMP1
17 aneurysm 10.1 ELN FBN1
18 epidermolysis bullosa pruriginosa 10.1 FLG MMP1
19 psoriasis 10.1
20 pseudoxanthoma elasticum 10.0 ELN FBN1
21 recessive dystrophic epidermolysis bullosa 10.0 FLG MMP1
22 open-angle glaucoma 10.0 ELN MMP1
23 lymphoma 10.0
24 cutaneous t cell lymphoma 10.0
25 senile ectropion 10.0 ELN MMP9
26 aortic aneurysm 9.9 ELN FBN1
27 contact dermatitis 9.9
28 t-cell leukemia 9.9
29 adult t-cell leukemia 9.9
30 spastic entropion 9.9 MMP1 MMP9
31 internal hemorrhoid 9.8 MMP1 MMP9
32 chromoblastomycosis 9.8 MMP1 MMP9
33 light chain deposition disease 9.8 MMP1 MMP9
34 adult astrocytic tumour 9.8 MMP1 MMP9
35 adenomyosis 9.8 MMP1 MMP9
36 odontogenic myxoma 9.8 MMP1 MMP9
37 chronic venous insufficiency 9.8 MMP1 MMP9
38 venous insufficiency 9.8 MMP1 MMP9
39 hypertensive heart disease 9.8 MMP1 MMP9
40 allergic contact dermatitis 9.8
41 multiple chemical sensitivity 9.8
42 biliary cirrhosis, primary, 1 9.8
43 primary biliary cholangitis 9.8
44 solar urticaria 9.8
45 leukemia 9.8
46 primary biliary cirrhosis 9.8
47 skin disease 9.8
48 osteomalacia 9.8
49 urticaria 9.8
50 exfoliation syndrome 9.7 ELN FBN1 MMP1

Graphical network of the top 20 diseases related to Chronic Actinic Dermatitis:



Diseases related to Chronic Actinic Dermatitis

Symptoms & Phenotypes for Chronic Actinic Dermatitis

Drugs & Therapeutics for Chronic Actinic Dermatitis

Search Clinical Trials , NIH Clinical Center for Chronic Actinic Dermatitis

Genetic Tests for Chronic Actinic Dermatitis

Anatomical Context for Chronic Actinic Dermatitis

MalaCards organs/tissues related to Chronic Actinic Dermatitis:

41
Skin, T Cells, Testes

Publications for Chronic Actinic Dermatitis

Articles related to Chronic Actinic Dermatitis:

(show top 50) (show all 120)
# Title Authors Year
1
Increased incidence of chronic actinic dermatitis in relation to climate changes and air pollution during the past 15 years in Korea. ( 29889316 )
2018
2
Chronic actinic dermatitis. ( 29530872 )
2018
3
Evaluation of narrow band ultraviolet B phototherapy in the treatment of chronic actinic dermatitis in Chinese patients. ( 29047198 )
2017
4
Phenotypic analysis of circulating T-cell subset and its association with burden of skin disease in patients with chronic actinic dermatitis: a hematologic and clinicopathologic study of 20 subjects. ( 28176301 )
2017
5
Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis. ( 28050588 )
2017
6
Genome-Wide Analysis of mRNA and Long Noncoding RNA Profiles in Chronic Actinic Dermatitis. ( 29359156 )
2017
7
Chronic actinic dermatitis: successful treatment with PUVA photochemotherapy. ( 28889653 )
2017
8
Comparison of Demographic and Photobiological Features of Chronic Actinic Dermatitis in Patients With Lighter vs Darker Skin Types. ( 28329062 )
2017
9
Tacrolimus 0.1% ointment applied under occlusion using cling film clears chronic actinic dermatitis resistant to systemic treatment. ( 28239836 )
2017
10
The Clinical Severity Score of Chronic Actinic Dermatitis (CSS-CAD) Correlates with In Vivo Photoallergic Reactions and the Immunologic Parameters related to a Shift towards Th2 Immunity from the Th2/Th1 Balanced Status in Patients with Chronic Actinic Dermatitis. ( 27084788 )
2016
11
Tungsten lamp and chronic actinic dermatitis. ( 26299466 )
2015
12
Chronic actinic dermatitis occurring in an adult with atopic dermatitis. ( 26990344 )
2015
13
Is photodynamic diagnostic flexible ureterorenoscopy suitable for a patient presenting with chronic actinic dermatitis? ( 26012562 )
2015
14
Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis. ( 25734812 )
2015
15
Chronic actinic dermatitis. ( 24891057 )
2014
16
The natural history of chronic actinic dermatitis: an analysis at a single institution in the United States. ( 24407058 )
2014
17
Chronic actinic dermatitis/actinic reticuloid: a clinicopathologic and immunohistochemical analysis of 37 cases. ( 25238449 )
2014
18
A case of false-negative monochromator phototesting in a patient with chronic actinic dermatitis taking prednisolone. ( 22250731 )
2012
19
Chronic actinic dermatitis with leonine facies and iatrogenic adrenal insufficiency successfully treated with topical tacrolimus. ( 21487461 )
2011
20
Chronic actinic dermatitis: two patients with successful management using narrowband ultraviolet B phototherapy with systemic steroids. ( 22031690 )
2011
21
Positive patch- and photopatch-test reactions to methylene bis-benzotriazolyl tetramethylbutylphenol in patients with both atopic dermatitis and chronic actinic dermatitis. ( 21504696 )
2011
22
Chronic actinic dermatitis: an analysis at a single institution over 25 years. ( 21569744 )
2011
23
Chronic actinic dermatitis in Asian skin: a Singaporean experience. ( 21729163 )
2011
24
False-negative monochromator phototesting in chronic actinic dermatitis. ( 20184579 )
2010
25
Treatment with topical tacrolimus favors chronic actinic dermatitis: a clinical and immunopathological study. ( 20394493 )
2010
26
Contact and photocontact sensitization in chronic actinic dermatitis: a changing picture. ( 20136878 )
2010
27
Chronic actinic dermatitis to sesquiterpene lactones: [2+2] photoreaction toward thymidine of (+) and (-) alpha-methylene-hexahydrobenzofuranone with a cis ring junction. ( 20113426 )
2010
28
Diagnosis and pharmacological treatment of chronic actinic dermatitis in the elderly: an update. ( 20524705 )
2010
29
The spontaneous resolution of photosensitivity and contact allergy in a patient with chronic actinic dermatitis. ( 19292791 )
2009
30
Case report of four patients with erythrodermic cutaneous T-cell lymphoma and severe photosensitivity mimicking chronic actinic dermatitis. ( 19067712 )
2009
31
Chronic actinic dermatitis: clinical cases, diagnostic workup, and therapeutic management. ( 19426619 )
2009
32
A Korean experience with chronic actinic dermatitis during an 18-year period: meteorological and photoimmunological aspects. ( 19906162 )
2009
33
Surgical management of chronic actinic dermatitis. ( 17765670 )
2008
34
[Expressions of fibrillin-1, elastin and matrix metalloproteinase-1 and -9 in chronic actinic dermatitis in elderly patients]. ( 18753059 )
2008
35
Chronic actinic dermatitis. ( 18627761 )
2008
36
Chronic actinic dermatitis in a patient with adult T-cell leukemia. ( 18477134 )
2008
37
Recalcitrant chronic actinic dermatitis treated with low-dose thalidomide. ( 15858462 )
2005
38
A case of chronic actinic dermatitis treated with topical tacrolimus. ( 16249148 )
2005
39
Chronic actinic dermatitis treated with mycophenolate mofetil. ( 15840115 )
2005
40
Successful treatment of chronic actinic dermatitis with topical pimecrolimus. ( 15811093 )
2005
41
Chronic actinic dermatitis--a study of clinical features. ( 16394483 )
2005
42
Exacerbation of presumed chronic actinic dermatitis by cockpit visible light in an airline pilot with atopic eczema. ( 15888133 )
2005
43
Chronic actinic dermatitis recognized on minimal erythema dose testing prior to narrow-band UVB treatment for psoriasis. ( 15752132 )
2005
44
Chronic actinic dermatitis associated with adult T-cell leukemia. ( 15692511 )
2005
45
Chronic actinic dermatitis in the elderly: recognition and treatment. ( 15813653 )
2005
46
Erythrodermic chronic actinic dermatitis responding only to topical tacrolimus. ( 14738535 )
2004
47
Chronic actinic dermatitis. ( 15533239 )
2004
48
Co-existence of chronic actinic dermatitis and solar urticaria in three patients. ( 15327570 )
2004
49
Chronic actinic dermatitis developing during narrowband UVB phototherapy for psoriasis. ( 14738538 )
2004
50
Successful treatment of recalcitrant chronic actinic dermatitis with tacrolimus. ( 15539897 )
2004

Variations for Chronic Actinic Dermatitis

Expression for Chronic Actinic Dermatitis

Search GEO for disease gene expression data for Chronic Actinic Dermatitis.

Pathways for Chronic Actinic Dermatitis

GO Terms for Chronic Actinic Dermatitis

Cellular components related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 8.92 ELN FBN1 MMP1 MMP9

Biological processes related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen catabolic process GO:0030574 9.16 MMP1 MMP9
2 extracellular matrix organization GO:0030198 9.13 ELN FBN1 MMP9
3 extracellular matrix disassembly GO:0022617 8.92 ELN FBN1 MMP1 MMP9

Molecular functions related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metalloendopeptidase activity GO:0004222 9.16 MMP1 MMP9
2 endopeptidase activity GO:0004175 8.96 MMP1 MMP9
3 extracellular matrix structural constituent GO:0005201 8.62 ELN FBN1

Sources for Chronic Actinic Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....