MCID: CHR463
MIFTS: 32

Chronic Actinic Dermatitis

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Chronic Actinic Dermatitis

MalaCards integrated aliases for Chronic Actinic Dermatitis:

Name: Chronic Actinic Dermatitis 59 72
Actinic Reticuloid 59 72 33
Chronic Photosensitivity Dermatitis 59

Characteristics:

Orphanet epidemiological data:

59
chronic actinic dermatitis
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 59  
Rare skin diseases


External Ids:

ICD10 33 L57.1
UMLS via Orphanet 73 C0282309 C1510437
Orphanet 59 ORPHA330064
UMLS 72 C0282309 C1510437

Summaries for Chronic Actinic Dermatitis

MalaCards based summary : Chronic Actinic Dermatitis, also known as actinic reticuloid, is related to dermatitis and mycosis fungoides. An important gene associated with Chronic Actinic Dermatitis is CCR7 (C-C Motif Chemokine Receptor 7), and among its related pathways/superpathways are Integrin Pathway and Degradation of the extracellular matrix. Affiliated tissues include skin, t cells and testes.

Wikipedia : 75 Chronic actinic dermatitis (also known as "Actinic reticuloid," "Chronic photosensitivity dermatitis,"... more...

Related Diseases for Chronic Actinic Dermatitis

Diseases related to Chronic Actinic Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 dermatitis 10.9
2 mycosis fungoides 10.6
3 dermatitis, atopic 10.4
4 contact dermatitis 10.4
5 cutaneous t cell lymphoma 10.3
6 aortic aneurysm 10.2 FBN1 ELN
7 pustulosis of palm and sole 10.2
8 psoriasis 10.2
9 late-onset focal dermal elastosis 10.2 FBN1 ELN
10 pseudoxanthoma elasticum 10.2 FBN1 ELN
11 pseudoxanthoma elasticum-like papillary dermal elastolysis 10.2 FBN1 ELN
12 familial abdominal aortic aneurysm 10.2 FBN1 ELN
13 mid-dermal elastolysis 10.2 FBN1 ELN
14 senile ectropion 10.2 MMP9 ELN
15 autosomal recessive cutis laxa type iii 10.2 FBN1 ELN
16 allergic contact dermatitis 10.2
17 phacogenic glaucoma 10.2 FBN1 ELN
18 supravalvular aortic stenosis 10.2 FBN1 ELN
19 aortic valve insufficiency 10.2 FBN1 ELN
20 cerebral arterial disease 10.2 MMP9 ELN
21 sorsby fundus dystrophy 10.1 FBN1 ELN
22 exanthem 10.1
23 cutis laxa, autosomal dominant 1 10.1 FBN1 ELN
24 kaposi sarcoma 10.1
25 porphyria cutanea tarda 10.1
26 ataxia-telangiectasia 10.1
27 bloom syndrome 10.1
28 xeroderma pigmentosum, variant type 10.1
29 ataxia and polyneuropathy, adult-onset 10.1
30 graft-versus-host disease 10.1
31 erythema multiforme 10.1
32 sarcoma 10.1
33 telangiectasis 10.1
34 porphyria 10.1
35 hidradenitis 10.1
36 spindle cell sarcoma 10.1
37 conjunctivitis 10.1
38 b-cell lymphoma 10.1
39 parapsoriasis 10.1
40 lichen planus 10.1
41 pityriasis lichenoides 10.1
42 posttransplant acute limbic encephalitis 10.1
43 cutaneous pseudolymphoma 10.1
44 heart valve disease 10.1 FBN1 ELN
45 lipoid proteinosis of urbach and wiethe 10.1 MMP9 FBN1
46 immune deficiency disease 10.0
47 adult t-cell leukemia 10.0
48 allergic hypersensitivity disease 10.0
49 spongiotic dermatitis 10.0
50 t-cell leukemia 10.0

Graphical network of the top 20 diseases related to Chronic Actinic Dermatitis:



Diseases related to Chronic Actinic Dermatitis

Symptoms & Phenotypes for Chronic Actinic Dermatitis

Drugs & Therapeutics for Chronic Actinic Dermatitis

Search Clinical Trials , NIH Clinical Center for Chronic Actinic Dermatitis

Genetic Tests for Chronic Actinic Dermatitis

Anatomical Context for Chronic Actinic Dermatitis

MalaCards organs/tissues related to Chronic Actinic Dermatitis:

41
Skin, T Cells, Testes, Lymph Node, Neutrophil

Publications for Chronic Actinic Dermatitis

Articles related to Chronic Actinic Dermatitis:

(show top 50) (show all 332)
# Title Authors PMID Year
1
Case report of chronic actinic dermatitis accompanied by ultraviolet A photosensitivity in a Chrysanthemum farmer. 38
30811065 2019
2
A case of chronic actinic dermatitis that responded completely to treatment with oral colostrum-macrophage-activating factor (colostrum-MAF). 38
30951213 2019
3
A case report of therapeutically challenging chronic actinic dermatitis. 38
31105944 2019
4
Increased incidence of chronic actinic dermatitis in relation to climate changes and air pollution during the past 15 years in Korea. 38
29889316 2018
5
Mogamulizumab-induced photosensitivity in patients with mycosis fungoides and other T-cell neoplasms. 38
29341283 2018
6
Allergic Contact Dermatitis-Induced Stereospecificity Overview. 38
29933255 2018
7
Chronic actinic dermatitis: successful treatment with psoralen-ultraviolet A photochemotherapy. 38
28889653 2018
8
Chronic actinic dermatitis. 38
29530872 2018
9
Photo-patch and patch tests in patients with dermatitis over the photo-exposed areas: A study of 101 cases from a tertiary care centre in India. 38
27282531 2018
10
Evaluation of narrow band ultraviolet B phototherapy in the treatment of chronic actinic dermatitis in Chinese patients. 38
29047198 2017
11
Tacrolimus 0.1% ointment applied under occlusion using cling film clears chronic actinic dermatitis resistant to systemic treatment. 38
28239836 2017
12
Comparison of Demographic and Photobiological Features of Chronic Actinic Dermatitis in Patients With Lighter vs Darker Skin Types. 38
28329062 2017
13
Phenotypic analysis of circulating T-cell subset and its association with burden of skin disease in patients with chronic actinic dermatitis: a hematologic and clinicopathologic study of 20 subjects. 38
28176301 2017
14
Tungsten lamp and chronic actinic dermatitis. 38
26299466 2017
15
Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis. 38
28050588 2017
16
High Altitude Dermatology. 38
28216727 2017
17
Genome-Wide Analysis of mRNA and Long Noncoding RNA Profiles in Chronic Actinic Dermatitis. 38
29359156 2017
18
The clinical severity score of chronic actinic dermatitis correlates with in vivo photoallergic reactions and the immunologic parameters related to a shift towards Th2 immunity from the Th2/Th1 balanced status in patients with chronic actinic dermatitis. 38
27084788 2016
19
Chronic actinic dermatitis occurring in an adult with atopic dermatitis. 38
26990344 2015
20
Human T-lymphotropic virus 1 (HTLV-1)-associated lichenoid dermatitis induced by CD8+ T cells in HTLV-1 carrier, HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T-cell leukemia/lymphoma. 38
26077665 2015
21
Is photodynamic diagnostic flexible ureterorenoscopy suitable for a patient presenting with chronic actinic dermatitis? 38
26012562 2015
22
Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis. 38
25734812 2015
23
Hair dye dermatitis and p-phenylenediamine contact sensitivity: A preliminary report. 38
26225326 2015
24
Chronic actinic dermatitis/actinic reticuloid: a clinicopathologic and immunohistochemical analysis of 37 cases. 38
25238449 2014
25
Evidence and conjecture about mechanisms of cutaneous disease in photodermatology. 38
24910168 2014
26
Evaluation of patients with photodermatoses. 38
24891050 2014
27
Chronic actinic dermatitis. 38
24891057 2014
28
The natural history of chronic actinic dermatitis: an analysis at a single institution in the United States. 38
24407058 2014
29
A clinical study of the spectrum of photodermatoses in dark-skinned populations. 38
23758593 2013
30
Energy-saving lamps and their impact on photosensitive and normal individuals. 38
23746038 2013
31
A quantitative assessment of the effects of formal sun protection education on photosensitive patients. 38
24001382 2013
32
Incidence and care of environmental dermatoses in the high-altitude region of ladakh, India. 38
23716798 2013
33
Parthenium dermatitis. 38
23139090 2013
34
Photodermatoses in pigmented skin. 38
23123922 2013
35
Origin Use of CD4, CD8, and CD1a Immunostains in Distinguishing Mycosis Fungoides from its Inflammatory Mimics: A Pilot Study. 38
23248358 2012
36
Actinic reticuloid imitating Sézary syndrome. 38
23267873 2012
37
Parthenium dermatitis in India: past, present and future. 38
22960811 2012
38
A case of false-negative monochromator phototesting in a patient with chronic actinic dermatitis taking prednisolone. 38
22250731 2012
39
A photosensitive pseudolymphomatous eruption. Actinic reticuloid (AR). 38
22340697 2012
40
Actinic reticuloid presented as facies leonine. 38
22250638 2012
41
Chronic actinic dermatitis: two patients with successful management using narrowband ultraviolet B phototherapy with systemic steroids. 38
22031690 2011
42
Actinic reticuloid--photosensitivity or pseudolymphoma?--A review. 38
22220464 2011
43
Chronic actinic dermatitis in Asian skin: a Singaporean experience. 38
21729163 2011
44
[Chronic actinic dermatitis. Therapy with systemic PUVA and mycophenolate mofetil]. 38
20941470 2011
45
The risk to normal and photosensitive individuals from exposure to light from compact fluorescent lamps. 38
21535166 2011
46
Chronic actinic dermatitis: an analysis at a single institution over 25 years. 38
21569744 2011
47
Off-label use of azathioprine in dermatology: a systematic review. 38
21482898 2011
48
Positive patch- and photopatch-test reactions to methylene bis-benzotriazolyl tetramethylbutylphenol in patients with both atopic dermatitis and chronic actinic dermatitis. 38
21504696 2011
49
Chronic actinic dermatitis with leonine facies and iatrogenic adrenal insufficiency successfully treated with topical tacrolimus. 38
21487461 2011
50
Diagnosis and pharmacological treatment of chronic actinic dermatitis in the elderly: an update. 38
20524705 2010

Variations for Chronic Actinic Dermatitis

Expression for Chronic Actinic Dermatitis

Search GEO for disease gene expression data for Chronic Actinic Dermatitis.

Pathways for Chronic Actinic Dermatitis

Pathways related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.79 MMP9 MMP1 FBN1 ELN CCR7
2
Show member pathways
12.11 MMP9 MMP1 FBN1 ELN
3 11.58 MMP9 MMP1
4
Show member pathways
11.51 MMP9 MMP1
5
Show member pathways
11.36 FBN1 ELN
6 11.34 MMP9 MMP1
7
Show member pathways
11.26 MMP9 MMP1
8 11.23 MMP9 ELN
9 11.19 MMP9 MMP1
10
Show member pathways
11.12 MMP9 MMP1 FBN1 ELN CCR7
11 10.9 MMP9 MMP1
12 10.72 MMP9 MMP1 ELN
13 10.55 MMP9 MMP1

GO Terms for Chronic Actinic Dermatitis

Cellular components related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 9.26 MMP9 MMP1 FBN1 ELN
2 collagen-containing extracellular matrix GO:0062023 8.92 MMP9 FLG FBN1 ELN

Biological processes related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix disassembly GO:0022617 9.16 MMP9 MMP1
2 collagen catabolic process GO:0030574 8.96 MMP9 MMP1
3 extracellular matrix organization GO:0030198 8.8 MMP9 FBN1 ELN

Molecular functions related to Chronic Actinic Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metalloendopeptidase activity GO:0004222 9.16 MMP9 MMP1
2 endopeptidase activity GO:0004175 8.96 MMP9 MMP1
3 extracellular matrix constituent conferring elasticity GO:0030023 8.62 FBN1 ELN

Sources for Chronic Actinic Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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