MCID: CHR085
MIFTS: 28

Chronic Cervicitis

Categories: Reproductive diseases

Aliases & Classifications for Chronic Cervicitis

MalaCards integrated aliases for Chronic Cervicitis:

Name: Chronic Cervicitis 12 54 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1513
NCIt 49 C27057
SNOMED-CT 67 56728002
UMLS 71 C0269062

Summaries for Chronic Cervicitis

Disease Ontology : 12 A cervicitis that is present for weeks or more.

MalaCards based summary : Chronic Cervicitis is related to cervicitis and cervical intraepithelial neoplasia. An important gene associated with Chronic Cervicitis is HSPA4 (Heat Shock Protein Family A (Hsp70) Member 4), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Oncogene Induced Senescence. Affiliated tissues include cervix, testes and uterus.

Related Diseases for Chronic Cervicitis

Diseases in the Cervicitis family:

Acute Cervicitis Chronic Cervicitis

Diseases related to Chronic Cervicitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 139)
# Related Disease Score Top Affiliating Genes
1 cervicitis 30.7 SERPIND1 GP6 GP5 CDKN2A
2 cervical intraepithelial neoplasia 29.8 KRT17 CDKN2A
3 cervix uteri carcinoma in situ 28.2 TP53 SERPIND1 KRT17 KLHL40 GP6 GP5
4 chronic gonorrhea of cervix 11.1
5 cervical adenosarcoma 10.4 GP6 GP5
6 focal epithelial hyperplasia 10.4 GP6 GP5
7 spinal cord injury 10.3
8 soft palate cancer 10.3 GP6 CDKN2A
9 comedo carcinoma 10.2 TP53 GP5
10 vulvar intraepithelial neoplasia 10.1 TP53 CDKN2A
11 ovarian seromucinous carcinoma 10.1 TP53 CDKN2A
12 esophagus verrucous carcinoma 10.1 TP53 CDKN2A
13 spitz nevus 10.1 TP53 CDKN2A
14 suppressor of tumorigenicity 3 10.1 TP53 CDKN2A
15 oral leukoplakia 10.1 TP53 CDKN2A
16 thyroid lymphoma 10.1 TP53 CDKN2A
17 non-invasive bladder papillary urothelial neoplasm 10.1 ZKSCAN3 TP53
18 dedifferentiated liposarcoma 10.1 TP53 CDKN2A
19 adult malignant schwannoma 10.1 TP53 CDKN2A
20 keratinizing squamous cell carcinoma 10.1 TP53 CDKN2A
21 urinary tract papillary transitional cell benign neoplasm 10.1 ZKSCAN3 TP53
22 cervical mucinous adenocarcinoma 10.1 TP53 CDKN2A
23 bladder papillary transitional cell neoplasm 10.1 ZKSCAN3 TP53
24 adult astrocytic tumour 10.1 TP53 CDKN2A
25 bladder clear cell adenocarcinoma 10.1 TP53 CDKN2A
26 urethra clear cell adenocarcinoma 10.1 TP53 CDKN2A
27 inverted follicular keratosis 10.1 KRT17 GP6 GP5
28 eccrine acrospiroma 10.1 TP53 KRT17
29 bone squamous cell carcinoma 10.1 TP53 CDKN2A
30 large cell acanthoma 10.1 TP53 KRT17
31 low-grade astrocytoma 10.0 TP53 CDKN2A
32 familial retinoblastoma 10.0 TP53 CDKN2A
33 megaesophagus 10.0 TP53 CDKN2A
34 nodular malignant melanoma 10.0 TP53 CDKN2A
35 laryngeal benign neoplasm 10.0 TP53 CDKN2A
36 clear cell basal cell carcinoma 10.0 TP53 KRT17
37 whiplash 10.0
38 anal squamous cell carcinoma 10.0 TP53 CDKN2A
39 peritoneum cancer 10.0 TP53 CDKN2A
40 epidermodysplasia verruciformis 1 10.0 TP53 GP6 GP5
41 endocervical carcinoma 10.0 TP53 CDKN2A
42 radiculopathy 10.0
43 supratentorial cancer 10.0 TP53 CDKN2A
44 vulva squamous cell carcinoma 9.9 TP53 GP5 CDKN2A
45 vaginal cancer 9.9 TP53 GP5 CDKN2A
46 vulvar disease 9.9 TP53 GP5 CDKN2A
47 laryngeal disease 9.9 TP53 SERPIND1 CDKN2A
48 vulva cancer 9.9 TP53 GP5 CDKN2A
49 penile cancer 9.9 TP53 GP5 CDKN2A
50 hypopharynx cancer 9.9 TP53 CDKN2A

Graphical network of the top 20 diseases related to Chronic Cervicitis:



Diseases related to Chronic Cervicitis

Symptoms & Phenotypes for Chronic Cervicitis

Drugs & Therapeutics for Chronic Cervicitis

Search Clinical Trials , NIH Clinical Center for Chronic Cervicitis

Genetic Tests for Chronic Cervicitis

Anatomical Context for Chronic Cervicitis

MalaCards organs/tissues related to Chronic Cervicitis:

40
Cervix, Testes, Uterus, Heart, Testis, Bone, Spinal Cord

Publications for Chronic Cervicitis

Articles related to Chronic Cervicitis:

(show top 50) (show all 317)
# Title Authors PMID Year
1
Expression of heat shock protein 70 and c-myc in cervical carcinoma. 54 61
9673366 1998
2
Relevance research between the expression of p16INK4a , Notch1, and hTERC genes: The development of HPV16-positive cervical cancer. 61
31976596 2020
3
Downregulation of Mad2 and BubR1 increase the malignant potential and nocodazole resistance by compromising spindle assembly checkpoint signaling pathway in cervical carcinogenesis. 61
31523901 2019
4
Ki-67 and P16 proteins in cervical cancer and precancerous lesions of young women and the diagnostic value for cervical cancer and precancerous lesions. 61
31423197 2019
5
A Clinical Conundrum: Chronic Cervicitis. 61
30582974 2019
6
Suppression of miR-93-5p inhibits high-risk HPV-positive cervical cancer progression via targeting of BTG3. 61
30689165 2019
7
Comparison of Chlorquinaldol-Promestriene Vaginal Tablets and Opin Suppositories Effect on Inflammatory Factors and Immune Function in Chronic HPV Cervicitis. 61
30700347 2019
8
Molecular Diagnosis of Human Papilloma Virus by PCR. 61
30755567 2019
9
Correlative analysis of the expression of IL-10 and Ki-67 in human cervical cancer and cervical intraepithelial neoplasias and human papillomavirus infection. 61
30546456 2018
10
Analysis of cervical human papillomavirus infection in 2300 women in Urumqi, China. 61
30407360 2018
11
Analysis of gene mutation associated with tyrosine kinase inhibitor sensitivity of epidermal growth factor receptor in cervical cancer patients. 61
30338793 2018
12
[The role of HPV E6/E7 mRNA combined with P16/ki67 immunocytochemistry in the diagnosis of atypical squamous cells of undetermined significance(ASCUS)]. 61
30554588 2018
13
Clinical Value of Human Papillomavirus E6/E7 mRNA Detection in Screening for Cervical Cancer in Women Positive for Human Papillomavirus DNA or. 61
30274003 2018
14
A prospective pilot evaluation of vaginal and urine self-sampling for the Roche cobas 4800 HPV test for cervical cancer screening. 61
29899531 2018
15
PP2A Inhibits Cervical Cancer Cell Migration by Dephosphorylation of p-JNK, p-p38 and the p-ERK/MAPK Signaling Pathway. 61
30074160 2018
16
[Paraffin section thickness in immunohistochemical detection of p16 expression in cervical tissue samples]. 61
30511522 2018
17
[Value of combined detection of claudin 4 and high-risk human papilloma virus in high-grade squamous intraepithelial lesion and cervix squamous cell carcinoma]. 61
30511519 2018
18
Human Papilloma Viruses and Their Genotype Distribution in Women with High Socioeconomic Status in Central Anatolia, Turkey: A Pilot Study. 61
29298972 2018
19
Expression and clinical significance of HOXA5, E-cadherin, and β-catenin in cervical squamous cell carcinoma. 61
31938436 2018
20
Chronic Cervicitis. 61
28232137 2018
21
Downregulation of nuclear and cytoplasmic Chibby is associated with advanced cervical cancer. 61
29181101 2017
22
Uterine Prolapse: Should Hysterectomy Specimens be Subjected for Histopathological Examination? 61
29307980 2017
23
Y Box-Binding Protein 1 Promotes Epithelial-Mesenchymal Transition, Invasion, and Metastasis of Cervical Cancer via Enhancing the Expressions of Snail. 61
28708785 2017
24
Effect of Dialyzable Leukocyte Extract on chronic cervicitis in patients with HPV infection. 61
29362599 2017
25
Clinicopathological significance of survivin expression in patients with cervical cancer: A systematic meta-analysis. 61
28051906 2017
26
STAT3 influences the characteristics of stem cells in cervical carcinoma. 61
28781654 2017
27
Detection of Human Papilloma virus by Molecular method from Patients Attending at Colposcopy Clinic of Mymensingh Medical College Hospital, Mymensingh. 61
28919616 2017
28
Comparative Study of Cytology and Histopathology of Cervical Lesion in VIA Positive Patients and Its Correlation with High Risk Human Papilloma Virus. 61
28919602 2017
29
Clinical efficacy of cryotherapy combined with interferon in the treatment of chronic cervicitis complicated with HPV infection. 61
29044006 2017
30
Mucin expression profile of benign and malignant cervical tissues and correlation with clinical-pathologic parameters. 61
29693871 2017
31
Down-regulation of IFITM1 and its growth inhibitory role in cervical squamous cell carcinoma. 61
29051711 2017
32
Human Papillomavirus Genotyping by Surface Plasmon Resonance-Based Test. 61
28164665 2016
33
Co-evolution of tumor-associated macrophages and tumor neo-vessels during cervical cancer invasion. 61
27698836 2016
34
Evaluation of 3D-CPA, HR-HPV, and TCT joint detection on cervical disease screening. 61
27446364 2016
35
Development and application of a rapid detection system for human papillomavirus and Herpes simplex virus-2 by loop-mediated isothermal amplification assay. 61
27287497 2016
36
[Pathogenic bacterium and drug resistance in cervical cancer patients complicated with reproductive tract infection]. 61
27592578 2016
37
Correlation of Cervical Pap Smear with Biopsy in the Lesion of Cervix. 61
28814689 2016
38
Evaluation and clinical significance of cyclin-dependent kinase5 expression in cervical lesions: a clinical research study in Guangxi, China. 61
27406233 2016
39
Chronic Cervicitis: Presenting Features and Response to Therapy. 61
27243142 2016
40
Diagnostic Approach to Patients with Atypical Squamous Cells of Undetermined Significance Cytologic Findings on Cervix. 61
27703293 2016
41
Prevalence of human papillomavirus genotypes among women with cervical lesions in the Shaanxi Province of China. 61
27051020 2016
42
Pathologic findings in women with atypical glandular cells on Pap test. 61
31042539 2016
43
[Expression and clinical significance of Dyrk1b in the specimens and cells of cervical lesions]. 61
26899006 2016
44
Spectrum of cervical lesions observed in 500 cases: Carcinoma cervix the leading cause of death in females. 61
27146743 2016
45
Correlation of P16 (Ink4a) and CK17 to HPV (16E6+18E6) in Premalignant and Malignant Lesions of Uterine Cervix: A Clinicopathologic Study. 61
28855930 2016
46
STAT3 correlates with stem cell-related transcription factors in cervical cancer. 61
26670442 2015
47
Expression levels of survivin, Bcl-2, and KAI1 proteins in cervical cancer and their correlation with metastasis. 61
26681053 2015
48
Analysis of Sensitivity, Specificity, and Positive and Negative Predictive Values of Smear and Colposcopy in Diagnosis of Premalignant and Malignant Cervical Lesions. 61
26655816 2015
49
[Expression of Daxx and HPV16 E6 and its significance in cervical lesions]. 61
26814089 2015
50
Unexpected premalignant gynecological lesions in women undergoing vaginal hysterectomy for utero-vaginal prolapse. 61
26528108 2015

Variations for Chronic Cervicitis

Expression for Chronic Cervicitis

Search GEO for disease gene expression data for Chronic Cervicitis.

Pathways for Chronic Cervicitis

GO Terms for Chronic Cervicitis

Biological processes related to Chronic Cervicitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.33 SERPIND1 GP6 GP5
2 replicative senescence GO:0090399 8.96 TP53 CDKN2A
3 hemostasis GO:0007599 8.8 SERPIND1 GP6 GP5

Sources for Chronic Cervicitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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