MCID: CHR085
MIFTS: 27

Chronic Cervicitis

Categories: Reproductive diseases
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Aliases & Classifications for Chronic Cervicitis

MalaCards integrated aliases for Chronic Cervicitis:

Name: Chronic Cervicitis 11 53 14 71

Classifications:



External Ids:

Disease Ontology 11 DOID:1513
NCIt 49 C27057
SNOMED-CT 68 198210003
UMLS 71 C0269062

Summaries for Chronic Cervicitis

Disease Ontology: 11 A cervicitis that is present for weeks or more.

MalaCards based summary: Chronic Cervicitis is related to cervicitis and cervical adenocarcinoma. An important gene associated with Chronic Cervicitis is HSPA4 (Heat Shock Protein Family A (Hsp70) Member 4), and among its related pathways/superpathways are 22q11.2 copy number variation syndrome and Platelet Adhesion to exposed collagen. Affiliated tissues include cervix, uterus and testis.

Related Diseases for Chronic Cervicitis

Diseases in the Cervicitis family:

Acute Cervicitis Chronic Cervicitis

Diseases related to Chronic Cervicitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 cervicitis 31.2 ZNF582 SERPIND1 GP6 GP5 CDKN2A
2 cervical adenocarcinoma 29.5 TP53 INSM1 CDKN2A
3 chronic gonorrhea of cervix 11.1
4 cervical cancer 10.3
5 cervical clear cell adenocarcinoma 10.3 GP5 CDKN2A
6 inverted follicular keratosis 10.3 GP6 GP5
7 cervical intraepithelial neoplasia 10.2
8 ovarian seromucinous carcinoma 10.2 PAX1 CDKN2A
9 soft palate cancer 10.2 GP6 CDKN2A
10 b-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) 10.2 TP53 CDKN2A
11 endometrial squamous cell carcinoma 10.2 TP53 CDKN2A
12 esophagus verrucous carcinoma 10.2 TP53 CDKN2A
13 comedo carcinoma 10.2 TP53 GP5
14 bizarre leiomyoma 10.1 TP53 CDKN2A
15 larynx squamous papilloma 10.1 TP53 CDKN2A
16 suppressor of tumorigenicity 3 10.1 TP53 CDKN2A
17 conjunctival squamous cell carcinoma 10.1 TP53 CDKN2A
18 bladder clear cell adenocarcinoma 10.1 TP53 CDKN2A
19 atypical neurofibroma 10.1 TP53 CDKN2A
20 lip cancer 10.1 TP53 CDKN2A
21 male urethral cancer 10.1 TP53 CDKN2A
22 middle ear squamous cell carcinoma 10.1 GP6 GP5 CDKN2A
23 penis basal cell carcinoma 10.1 GP6 GP5 CDKN2A
24 lymphoepithelioma-like carcinoma 10.1 TP53 CDKN2A
25 keratinizing squamous cell carcinoma 10.1 TP53 CDKN2A
26 paranasal sinus cancer 10.1 TP53 CDKN2A
27 idh-wildtype glioblastoma 10.1 TP53 CDKN2A
28 bone squamous cell carcinoma 10.1 TP53 CDKN2A
29 adult malignant schwannoma 10.1 TP53 CDKN2A
30 pleomorphic xanthoastrocytoma 10.1 TP53 CDKN2A
31 malignant spindle cell melanoma 10.1 TP53 CDKN2A
32 borst-jadassohn intraepidermal carcinoma 10.1 TP53 CDKN2A
33 mixed glioma 10.1 TP53 CDKN2A
34 chlamydia 10.1
35 barrett's adenocarcinoma 10.1 TP53 CDKN2A
36 conjunctival cancer 10.1 TP53 CDKN2A
37 neurofibrosarcoma 10.1 TP53 CDKN2A
38 anal squamous cell carcinoma 10.0 ZNF582 TP53 CDKN2A
39 squamous cell papilloma 10.0 TP53 GP5 CDKN2A
40 penile benign neoplasm 10.0 TP53 GP5 CDKN2A
41 acanthoma 10.0 TP53 CDKN2A
42 male reproductive organ benign neoplasm 10.0 TP53 GP5 CDKN2A
43 phimosis 10.0 TP53 GP5 CDKN2A
44 verrucous carcinoma 10.0 TP53 GP5 CDKN2A
45 vulvar disease 10.0 TP53 GP5 CDKN2A
46 penile disease 10.0 TP53 GP5 CDKN2A
47 focal epithelial hyperplasia 10.0 TP53 GP6 GP5
48 cervical adenosarcoma 10.0 TP53 GP6 GP5
49 nodular malignant melanoma 10.0 TP53 CDKN2A
50 rectal disease 10.0 TP53 GP5 CDKN2A

Graphical network of the top 20 diseases related to Chronic Cervicitis:



Diseases related to Chronic Cervicitis

Symptoms & Phenotypes for Chronic Cervicitis

Drugs & Therapeutics for Chronic Cervicitis

Search Clinical Trials, NIH Clinical Center for Chronic Cervicitis

Genetic Tests for Chronic Cervicitis

Anatomical Context for Chronic Cervicitis

Organs/tissues related to Chronic Cervicitis:

MalaCards : Cervix, Uterus, Testis, Thyroid

Publications for Chronic Cervicitis

Articles related to Chronic Cervicitis:

(show top 50) (show all 360)
# Title Authors PMID Year
1
Expression of heat shock protein 70 and c-myc in cervical carcinoma. 53 62
9673366 1998
2
Could HPV Type 33 Be More Risky Than We Thought? 62
36471500 2022
3
Diagnostic value of colposcopy in patients with cytology-negative and HR-HPV-positive cervical lesions. 62
35320389 2022
4
Evaluation of 5-aminolevulinic acid-mediated photodynamic therapy in postmenopausal women with persistent HPV infection with or without cervical and vaginal low-grade squamous intraepithelial lesions (CIN1/VaIN1). 62
35830950 2022
5
ThinPrep cytologic test combined with HPV typing to evaluate the degree of cervical diseases and the relationship between HPV typing and the pathological results of patients with atypical squamous cells of undetermined significance: a diagnostic test. 62
36237241 2022
6
Papillary thyroid cancer with suspicious uterine cervix metastasis: a case report and literature review. 62
35935566 2022
7
ROC-Analysis Derived Immunohistochemical P53 Cut-Off Scores as an Adjunct to Routine Histopathology for Better Diagnostic Compartmentalisation of Cervical Lesions. 62
36131854 2022
8
Shotgun Lipidomics for Differential Diagnosis of HPV-Associated Cervix Transformation. 62
35736434 2022
9
Loop Electrosurgical Excision Procedure under Propofol Intravenous Anesthesia Combined with Nano-Silver Gel in the Treatment of Cervicitis. 62
35988193 2022
10
Lower accuracy of cytological screening for high-grade squamous intraepithelial neoplasia in women over 50 years of age in Japan. 62
34873649 2022
11
Analysis of Serum Levels of IFN-γ, IL-4, and TNF-α in Patients with Cervicitis Complicated by HPV Infection and Their Clinical Significance. 62
35463689 2022
12
Characterization of allergic inflammation in chronic uterine cervicitis. 62
35020843 2022
13
Chronic Cervicitis and Cervical Cancer Detection Based on Deep Learning of Colposcopy Images Toward Translational Pharmacology. 62
35712722 2022
14
Analysis of Distributions of HPV Infection in Females with Cervical Lesions in the Western District of Beijing Chaoyang Hospital. 62
35320994 2022
15
Diagnostic Usefulness of p16 Immunohistochemistry for some Epithelial Lesions in the Pathology Service of Sultan Qaboos University Hospital. 62
35261666 2021
16
Congenital Transformation Zone Mimicking Cervical Premalignant Lesion. 62
34602771 2021
17
"Screen and Treat" Approach among VIA Positive Women during Cervical Cancer Screening Program: Experience at Low Resource Setting. 62
34605483 2021
18
Histomorphological Spectrum of Cervical Lesions in a Rural Hospital. 62
34722069 2021
19
Effectiveness of focused ultrasound for high risk human papillomavirus infection-related cervical lesions. 62
34420437 2021
20
Detection of DKK-1 gene methylation in exfoliated cells of cervical squamous cell carcinoma and its relationship with high risk HPV infection. 62
33547934 2021
21
Photodetection and Safety of 5-Aminolevulinic Acid-Induced Porphyrin in Patients With Cervical Intraepithelial Neoplasia. 62
33161594 2021
22
Histopathological Account of Obstetrical and Gynecological Specimens: Retrospective Study at a Tertiary Care Center of Peshawar. 62
34123647 2021
23
[The Clinical Significance of HPV L1/PD-L1 Tests Combined with Colposcopy for Cervical Precancerous Lesions and Cervical Cancer]. 62
34018374 2021
24
The application value of PAX1 and ZNF582 gene methylation in high grade intraepithelial lesion and cervical cancer. 62
32514824 2021
25
Expression and clinicopathological significance of Foxp3 and VISTA in cervical cancer. 62
34650712 2021
26
Single-Cell RNA Sequencing Reveals Multiple Pathways and the Tumor Microenvironment Could Lead to Chemotherapy Resistance in Cervical Cancer. 62
34900703 2021
27
The Help of HPV Integration Testing to Avoid the Misdiagnosis of a Patient with Stage Ia1 Cervical Cancer: A Case Report and Literature Review. 62
34819743 2021
28
The Value and Clinical Significance of ZNF582 Gene Methylation in the Diagnosis of Cervical Cancer. 62
33488095 2021
29
Correlation between multi-type human papillomavirus infections and viral loads and the cervical pathological grade. 62
33020921 2021
30
B7-H4 Expression in Precancerous Lesions of the Uterine Cervix. 62
34651047 2021
31
Application Value of Detection of High-Risk HPV Infection in Early Cervical Cancer Patients in Disease Diagnosis and Prognosis Evaluation. 62
33337824 2020
32
Re-evaluation of Negative Cone Biopsy Results with Ki-67 and p16 Immunostaining following Positive Cervical Biopsy. 62
33281264 2020
33
Cytological, Colposcopic and Pathohistological Correlation of HSIL and ASC H Findings. 62
33424094 2020
34
Role of molecular biomarker human papilloma virus (HPV) E6 oncoprotein in cervical cancer screening. 62
32680634 2020
35
Streptococcus agalactiae-Induced Soft Tissue Infection in a Nonpregnant Adult After a Gynecological Procedure. 62
32680980 2020
36
Associations between the expression of SCCA, MTA1, P16, Ki-67 and the infection of high-risk HPV in cervical lesions. 62
32566016 2020
37
Relevance research between the expression of p16INK4a , Notch1, and hTERC genes: The development of HPV16-positive cervical cancer. 62
31976596 2020
38
p16/Ki-67 dual-stained cytology used for triage in cervical cancer opportunistic screening. 62
32410798 2020
39
An effective UFLC-MS/MS method used to study pharmacokinetics of major constituents of Fukeqianjin formula in rat plasma. 62
32724332 2020
40
[The value of P16/ki67 double labeling, HPV E6/E7 mRNA detection and their combined application in cytological shunt diagnosis of low-grade squamous intraepithelial lesions]. 62
32314725 2020
41
Assessment of p16 and Ki67 Immunohistochemistry Expression in Squamous Intraepithelial Lesion with Cytohistomorphological Correlation. 62
32944038 2020
42
Downregulation of Mad2 and BubR1 increase the malignant potential and nocodazole resistance by compromising spindle assembly checkpoint signaling pathway in cervical carcinogenesis. 62
31523901 2019
43
Ki-67 and P16 proteins in cervical cancer and precancerous lesions of young women and the diagnostic value for cervical cancer and precancerous lesions. 62
31423197 2019
44
A Clinical Conundrum: Chronic Cervicitis. 62
30582974 2019
45
Suppression of miR-93-5p inhibits high-risk HPV-positive cervical cancer progression via targeting of BTG3. 62
30689165 2019
46
Comparison of Chlorquinaldol-Promestriene Vaginal Tablets and Opin Suppositories Effect on Inflammatory Factors and Immune Function in Chronic HPV Cervicitis. 62
30700347 2019
47
Molecular Diagnosis of Human Papilloma Virus by PCR. 62
30755567 2019
48
Correlative analysis of the expression of IL-10 and Ki-67 in human cervical cancer and cervical intraepithelial neoplasias and human papillomavirus infection. 62
30546456 2018
49
Analysis of cervical human papillomavirus infection in 2300 women in Urumqi, China. 62
30407360 2018
50
[The role of HPV E6/E7 mRNA combined with P16/ki67 immunocytochemistry in the diagnosis of atypical squamous cells of undetermined significance(ASCUS)]. 62
30554588 2018

Variations for Chronic Cervicitis

Expression for Chronic Cervicitis

Search GEO for disease gene expression data for Chronic Cervicitis.

Pathways for Chronic Cervicitis

Pathways related to Chronic Cervicitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.25 TP53 SERPIND1 GP5
2
Show member pathways
10.75 GP6 GP5
3 10.6 TP53 CDKN2A
4
Show member pathways
10.46 TP53 CDKN2A
5 9.85 TP53 CDKN2A

GO Terms for Chronic Cervicitis

Biological processes related to Chronic Cervicitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.35 SERPIND1 GP6 GP5
2 hemostasis GO:0007599 8.8 SERPIND1 GP6 GP5

Sources for Chronic Cervicitis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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