MCID: CHR085
MIFTS: 25

Chronic Cervicitis

Categories: Reproductive diseases

Aliases & Classifications for Chronic Cervicitis

MalaCards integrated aliases for Chronic Cervicitis:

Name: Chronic Cervicitis 12 55 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:1513
NCIt 50 C27057
SNOMED-CT 68 56728002
UMLS 72 C0269062

Summaries for Chronic Cervicitis

Disease Ontology : 12 A cervicitis that is present for weeks or more.

MalaCards based summary : Chronic Cervicitis is related to cervicitis and cervix uteri carcinoma in situ. An important gene associated with Chronic Cervicitis is SERPIND1 (Serpin Family D Member 1). Affiliated tissues include cervix, testes and uterus, and related phenotypes are Synthetic lethal with gemcitabine and hematopoietic system

Related Diseases for Chronic Cervicitis

Diseases in the Cervicitis family:

Acute Cervicitis Chronic Cervicitis

Diseases related to Chronic Cervicitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 cervicitis 30.5 SLC12A4 SERPIND1 CDKN2A
2 cervix uteri carcinoma in situ 29.5 SERPIND1 GP6 CDKN2A
3 cervical intraepithelial neoplasia 29.0 TERC CDKN2A
4 chronic gonorrhea of cervix 11.1
5 spinal cord injury 10.3
6 anogenital venereal wart 10.1 GP6 CDKN2A
7 balanoposthitis 10.0 GP6 CDKN2A
8 whiplash 10.0
9 penile disease 10.0 GP6 CDKN2A
10 pre-malignant neoplasm 10.0 SERPIND1 CDKN2A
11 radiculopathy 10.0
12 laryngeal disease 9.9 SERPIND1 CDKN2A
13 cervical adenitis 9.9
14 in situ carcinoma 9.8 SERPIND1 CDKN2A
15 spondylosis, cervical 9.8
16 cervical cancer 9.8
17 lymphadenitis 9.8
18 spondylosis 9.8
19 infertility 9.8
20 wallerian degeneration 9.8
21 headache 9.8
22 hypoxia 9.8
23 uterus carcinoma in situ 9.8 SERPIND1 GP6 CDKN2A
24 cervix disease 9.8 SERPIND1 GP6 CDKN2A
25 uterine anomalies 9.8 SERPIND1 GP6 CDKN2A
26 endometritis 9.7
27 chlamydia 9.7
28 quadriplegia 9.7
29 carotid artery occlusion 9.7
30 osteochondrosis 9.7
31 herpes simplex 9.7
32 aneurysm 9.7
33 autonomic dysfunction 9.7
34 back pain 9.7
35 chronic pain 9.7
36 spasticity 9.7
37 arteries, anomalies of 9.6
38 cardiac conduction defect 9.6
39 sprengel deformity 9.6
40 ossification of the posterior longitudinal ligament of spine 9.6
41 leukemia, acute lymphoblastic 9.6
42 hyperprolactinemia 9.6
43 hyperlipoproteinemia, type iii 9.6
44 adenoiditis 9.6
45 ectopic pregnancy 9.6
46 endometrial hyperplasia 9.6
47 pelvic inflammatory disease 9.6
48 osteomyelitis 9.6
49 lymphocytic leukemia 9.6
50 dirofilariasis 9.6

Graphical network of the top 20 diseases related to Chronic Cervicitis:



Diseases related to Chronic Cervicitis

Symptoms & Phenotypes for Chronic Cervicitis

GenomeRNAi Phenotypes related to Chronic Cervicitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with gemcitabine GR00225-A 8.62 CDKN2A RIPK4

MGI Mouse Phenotypes related to Chronic Cervicitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.1 CDKN2A DYRK1B GP6 RIPK4 SERPIND1 SLC12A4

Drugs & Therapeutics for Chronic Cervicitis

Search Clinical Trials , NIH Clinical Center for Chronic Cervicitis

Genetic Tests for Chronic Cervicitis

Anatomical Context for Chronic Cervicitis

MalaCards organs/tissues related to Chronic Cervicitis:

41
Cervix, Testes, Uterus, Testis

Publications for Chronic Cervicitis

Articles related to Chronic Cervicitis:

(show top 50) (show all 314)
# Title Authors PMID Year
1
Expression of heat shock protein 70 and c-myc in cervical carcinoma. 9 38
9673366 1998
2
Ki-67 and P16 proteins in cervical cancer and precancerous lesions of young women and the diagnostic value for cervical cancer and precancerous lesions. 38
31423197 2019
3
A Clinical Conundrum: Chronic Cervicitis. 38
30582974 2019
4
Suppression of miR-93-5p inhibits high-risk HPV-positive cervical cancer progression via targeting of BTG3. 38
30689165 2019
5
Comparison of Chlorquinaldol-Promestriene Vaginal Tablets and Opin Suppositories Effect on Inflammatory Factors and Immune Function in Chronic HPV Cervicitis. 38
30700347 2019
6
Molecular Diagnosis of Human Papilloma Virus by PCR. 38
30755567 2019
7
Correlative analysis of the expression of IL-10 and Ki-67 in human cervical cancer and cervical intraepithelial neoplasias and human papillomavirus infection. 38
30546456 2018
8
Analysis of cervical human papillomavirus infection in 2300 women in Urumqi, China. 38
30407360 2018
9
Analysis of gene mutation associated with tyrosine kinase inhibitor sensitivity of epidermal growth factor receptor in cervical cancer patients. 38
30338793 2018
10
[The role of HPV E6/E7 mRNA combined with P16/ki67 immunocytochemistry in the diagnosis of atypical squamous cells of undetermined significance(ASCUS)]. 38
30554588 2018
11
Clinical Value of Human Papillomavirus E6/E7 mRNA Detection in Screening for Cervical Cancer in Women Positive for Human Papillomavirus DNA or. 38
30274003 2018
12
A prospective pilot evaluation of vaginal and urine self-sampling for the Roche cobas 4800 HPV test for cervical cancer screening. 38
29899531 2018
13
[Paraffin section thickness in immunohistochemical detection of p16 expression in cervical tissue samples]. 38
30511522 2018
14
PP2A Inhibits Cervical Cancer Cell Migration by Dephosphorylation of p-JNK, p-p38 and the p-ERK/MAPK Signaling Pathway. 38
30074160 2018
15
[Value of combined detection of claudin 4 and high-risk human papilloma virus in high-grade squamous intraepithelial lesion and cervix squamous cell carcinoma]. 38
30511519 2018
16
Human Papilloma Viruses and Their Genotype Distribution in Women with High Socioeconomic Status in Central Anatolia, Turkey: A Pilot Study. 38
29298972 2018
17
Chronic Cervicitis. 38
28232137 2018
18
Downregulation of nuclear and cytoplasmic Chibby is associated with advanced cervical cancer. 38
29181101 2017
19
Y Box-Binding Protein 1 Promotes Epithelial-Mesenchymal Transition, Invasion, and Metastasis of Cervical Cancer via Enhancing the Expressions of Snail. 38
28708785 2017
20
Uterine Prolapse: Should Hysterectomy Specimens be Subjected for Histopathological Examination? 38
29307980 2017
21
Effect of Dialyzable Leukocyte Extract on chronic cervicitis in patients with HPV infection. 38
29362599 2017
22
Clinicopathological significance of survivin expression in patients with cervical cancer: A systematic meta-analysis. 38
28051906 2017
23
STAT3 influences the characteristics of stem cells in cervical carcinoma. 38
28781654 2017
24
Detection of Human Papilloma virus by Molecular method from Patients Attending at Colposcopy Clinic of Mymensingh Medical College Hospital, Mymensingh. 38
28919616 2017
25
Comparative Study of Cytology and Histopathology of Cervical Lesion in VIA Positive Patients and Its Correlation with High Risk Human Papilloma Virus. 38
28919602 2017
26
Clinical efficacy of cryotherapy combined with interferon in the treatment of chronic cervicitis complicated with HPV infection. 38
29044006 2017
27
Mucin expression profile of benign and malignant cervical tissues and correlation with clinical-pathologic parameters. 38
29693871 2017
28
Down-regulation of IFITM1 and its growth inhibitory role in cervical squamous cell carcinoma. 38
29051711 2017
29
Human Papillomavirus Genotyping by Surface Plasmon Resonance-Based Test. 38
28164665 2016
30
Co-evolution of tumor-associated macrophages and tumor neo-vessels during cervical cancer invasion. 38
27698836 2016
31
Evaluation of 3D-CPA, HR-HPV, and TCT joint detection on cervical disease screening. 38
27446364 2016
32
Development and application of a rapid detection system for human papillomavirus and Herpes simplex virus-2 by loop-mediated isothermal amplification assay. 38
27287497 2016
33
Correlation of Cervical Pap Smear with Biopsy in the Lesion of Cervix. 38
28814689 2016
34
Chronic Cervicitis: Presenting Features and Response to Therapy. 38
27243142 2016
35
Evaluation and clinical significance of cyclin-dependent kinase5 expression in cervical lesions: a clinical research study in Guangxi, China. 38
27406233 2016
36
[Pathogenic bacterium and drug resistance in cervical cancer patients complicated with reproductive tract infection]. 38
27592578 2016
37
Diagnostic Approach to Patients with Atypical Squamous Cells of Undetermined Significance Cytologic Findings on Cervix. 38
27703293 2016
38
Prevalence of human papillomavirus genotypes among women with cervical lesions in the Shaanxi Province of China. 38
27051020 2016
39
Spectrum of cervical lesions observed in 500 cases: Carcinoma cervix the leading cause of death in females. 38
27146743 2016
40
[Expression and clinical significance of Dyrk1b in the specimens and cells of cervical lesions]. 38
26899006 2016
41
Pathologic findings in women with atypical glandular cells on Pap test. 38
31042539 2016
42
Correlation of P16 (Ink4a) and CK17 to HPV (16E6+18E6) in Premalignant and Malignant Lesions of Uterine Cervix: A Clinicopathologic Study. 38
28855930 2016
43
STAT3 correlates with stem cell-related transcription factors in cervical cancer. 38
26670442 2015
44
Expression levels of survivin, Bcl-2, and KAI1 proteins in cervical cancer and their correlation with metastasis. 38
26681053 2015
45
Analysis of Sensitivity, Specificity, and Positive and Negative Predictive Values of Smear and Colposcopy in Diagnosis of Premalignant and Malignant Cervical Lesions. 38
26655816 2015
46
[Expression of Daxx and HPV16 E6 and its significance in cervical lesions]. 38
26814089 2015
47
Unexpected premalignant gynecological lesions in women undergoing vaginal hysterectomy for utero-vaginal prolapse. 38
26528108 2015
48
Cytopathological Examination and Epidemiological Study of Cervicitis in Commercial Sex Workers (CSWs) in Coal City (Enugu), Nigeria. 38
26633925 2015
49
Increased RIPK4 expression is associated with progression and poor prognosis in cervical squamous cell carcinoma patients. 38
26148476 2015
50
[Relationship of Human Papillomavirus Subtypes and Multiple Infection with Different Cervical Precancerous Diseases in Sichuan Province]. 38
26121866 2015

Variations for Chronic Cervicitis

Expression for Chronic Cervicitis

Search GEO for disease gene expression data for Chronic Cervicitis.

Pathways for Chronic Cervicitis

GO Terms for Chronic Cervicitis

Biological processes related to Chronic Cervicitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hemostasis GO:0007599 8.62 SERPIND1 GP6

Sources for Chronic Cervicitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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