MCID: CHR686
MIFTS: 19

Chronic Cutaneous Lupus Erythematosus

Categories: Immune diseases, Rare diseases, Skin diseases

Aliases & Classifications for Chronic Cutaneous Lupus Erythematosus

MalaCards integrated aliases for Chronic Cutaneous Lupus Erythematosus:

Name: Chronic Cutaneous Lupus Erythematosus 58

Characteristics:

Orphanet epidemiological data:

58
chronic cutaneous lupus erythematosus
Inheritance: Multigenic/multifactorial; Age of onset: Adolescent,Adult,Childhood,Infancy;

Classifications:

Orphanet: 58  
Rare skin diseases


External Ids:

ICD10 via Orphanet 33 L93.0 L93.2
Orphanet 58 ORPHA163531

Summaries for Chronic Cutaneous Lupus Erythematosus

MalaCards based summary : Chronic Cutaneous Lupus Erythematosus is related to lupus erythematosus tumidus and cutaneous lupus erythematosus. The drug Tyrosine has been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and b cells.

Related Diseases for Chronic Cutaneous Lupus Erythematosus

Diseases in the Cutaneous Lupus Erythematosus family:

Rare Cutaneous Lupus Erythematosus Subacute Cutaneous Lupus Erythematosus
Chronic Cutaneous Lupus Erythematosus

Diseases related to Chronic Cutaneous Lupus Erythematosus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 46)
# Related Disease Score Top Affiliating Genes
1 lupus erythematosus tumidus 11.5
2 cutaneous lupus erythematosus 10.8
3 lupus erythematosus 10.8
4 alopecia 10.4
5 discoid lupus erythematosus 10.4
6 autoimmune disease 10.2
7 skin disease 10.2
8 dermatomyositis 10.1
9 panniculitis 10.1
10 frontal fibrosing alopecia 10.1
11 neurofibromatosis, type ii 9.9
12 systemic lupus erythematosus 9.9
13 dowling-degos disease 1 9.9
14 sarcoidosis 1 9.9
15 vitiligo-associated multiple autoimmune disease susceptibility 6 9.9
16 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
17 mycosis fungoides 9.9
18 pseudoxanthoma elasticum 9.9
19 malignant atrophic papulosis 9.9
20 dermatitis, atopic 9.9
21 vitiligo-associated multiple autoimmune disease susceptibility 1 9.9
22 retinal dystrophy, iris coloboma, and comedogenic acne syndrome 9.9
23 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 9.9
24 pulmonary hypertension 9.9
25 exanthem 9.9
26 erythema elevatum diutinum 9.9
27 xerophthalmia 9.9
28 keratoconjunctivitis sicca 9.9
29 skin sarcoidosis 9.9
30 aggressive periodontitis 9.9
31 keratosis 9.9
32 squamous cell carcinoma 9.9
33 dermatitis 9.9
34 antiphospholipid syndrome 9.9
35 myopathy 9.9
36 complement deficiency 9.9
37 connective tissue disease 9.9
38 periodontitis 9.9
39 lichen planus 9.9
40 alopecia areata 9.9
41 47,xyy 9.9
42 erythrokeratoderma ''en cocardes'' 9.9
43 raynaud phenomenon 9.9
44 depression 9.9
45 posttransplant acute limbic encephalitis 9.9
46 subacute cutaneous lupus erythematosus 9.9

Graphical network of the top 20 diseases related to Chronic Cutaneous Lupus Erythematosus:



Diseases related to Chronic Cutaneous Lupus Erythematosus

Symptoms & Phenotypes for Chronic Cutaneous Lupus Erythematosus

Drugs & Therapeutics for Chronic Cutaneous Lupus Erythematosus

Drugs for Chronic Cutaneous Lupus Erythematosus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tyrosine Approved, Investigational, Nutraceutical Phase 1 60-18-4 6057

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Double-blind (Sponsor Unblinded) Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of Repeat Dosing of GSK2646264 in Cutaneous Lupus Erythematosus Patients Completed NCT02927457 Phase 1 GSK2646264 1%;Placebo

Search NIH Clinical Center for Chronic Cutaneous Lupus Erythematosus

Genetic Tests for Chronic Cutaneous Lupus Erythematosus

Anatomical Context for Chronic Cutaneous Lupus Erythematosus

MalaCards organs/tissues related to Chronic Cutaneous Lupus Erythematosus:

40
Skin, T Cells, B Cells, Testes, Neutrophil

Publications for Chronic Cutaneous Lupus Erythematosus

Articles related to Chronic Cutaneous Lupus Erythematosus:

(show top 50) (show all 143)
# Title Authors PMID Year
1
A secondary discoid lupus erythematosus induced by scald of edible oil: An illustration of Koebner phenomenon. 61
31660688 2020
2
Scarring alopecia in chronic cutaneous lupus erythematosus with neutrophils: A new scenario with therapeutic connotations. 61
32483922 2020
3
Cutaneous lupus erythematosus: factors related to cutaneous activity and damage in a cohort of 260 patients from A Coruña, Spain. 61
32539659 2020
4
Chronic cutaneous lupus erythematosus (discoid lupus) induced by palbociclib. 61
31724158 2020
5
Persistent Facial Oedema and Erythema in a Woman, An Uncommon Manifestation of Chronic Cutaneous Lupus Erythematosus. 61
32206644 2020
6
A comedonal variant of chronic cutaneous lupus erythematosus: Case report and literature review. 61
31517002 2019
7
Intravenous immunoglobulin G use in patients with chronic inflammatory demyelinating polyneuropathy: An uncommon cause of drug-induced discoid lupus erythematosus. 61
30734274 2019
8
Spectrum of cutaneous lupus erythematosus in South Africans with systemic lupus erythematosus. 61
31215844 2019
9
Chronic Cutaneous Lupus Erythematosus: Depression Burden and Associated Factors. 61
30877492 2019
10
An Unusual Morphological and Distribution Pattern of Chronic Cutaneous Lupus Erythematosus. 61
31149584 2019
11
Racial Disparities in the Incidence of Primary Chronic Cutaneous Lupus Erythematosus in the Southeastern US: The Georgia Lupus Registry. 61
29669194 2019
12
Current Insights Into The Management Of Discoid Lupus Erythematosus. 61
31632120 2019
13
In silico Analyses of Skin and Peripheral Blood Transcriptional Data in Cutaneous Lupus Reveals CCR2-A Novel Potential Therapeutic Target. 61
30984198 2019
14
Lupus panniculitis: Clinicopathological features of a series of 12 patients. 61
30154008 2018
15
Skin signs in juvenile- and adult-onset systemic lupus erythematosus: clues to different systemic involvement. 61
30336755 2018
16
A comprehensive review of immune-mediated dermatopathology in systemic lupus erythematosus. 61
30017673 2018
17
Chronic cutaneous lupus erythematosus and topical clindamycin. 61
30249740 2018
18
Fogo selvagem: endemic pemphigus foliaceus. 61
30156612 2018
19
CXCL13 is an activity marker for systemic, but not cutaneous lupus erythematosus: a longitudinal cohort study. 61
29728857 2018
20
Bizarre appearance of chronic cutaneous lupus erythematosus of face mimicking factitial dermatitis. 61
29224226 2018
21
Chronic cutaneous lupus erythematosus presenting as atypical acneiform and comedonal plaque: case report and literature review. 61
28857716 2018
22
The involvement of galectin-3 in skin injury in systemic lupus erythematosus patients. 61
29058991 2018
23
Coexistence of chronic cutaneous lupus erythematosus and frontal fibrosing alopecia. 61
29723351 2018
24
Chronic Cutaneous Lupus Erythematosus in a Blaschkoid Pattern over Face. 61
29692464 2018
25
Chronic cutaneous lupus erythematosus revealed by unilateral eyelid oedema. 61
28943504 2017
26
Cutaneous Lupus: A Brief Review of Old and New Medical Therapeutic Options. 61
28941497 2017
27
Pigmented macular variant of chronic cutaneous lupus erythematosus: an under-recognized subset in dark skin. 61
28590034 2017
28
Histologic features of chronic cutaneous lupus erythematosus of the scalp using horizontal sectioning: Emphasis on follicular findings. 61
28624120 2017
29
The Increased Expression of Toll-Like Receptor 4 in Renal and Skin Lesions in Lupus Erythematosus. 61
28530841 2017
30
Lupus profundus limited to a site of trauma: Case report and review of the literature. 61
28560307 2017
31
Lupus erythematosus tumidus of the scalp masquerading as alopecia areata. 61
28319635 2017
32
Methimazole-induced chronic cutaneous lupus erythematosus. 61
27519167 2017
33
Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases). 61
27747960 2016
34
[Systemic lupus erythematosus : Unusual cutaneous manifestations]. 61
27878308 2016
35
Primary cicatricial alopecia: Lymphocytic primary cicatricial alopecias, including chronic cutaneous lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, and Graham-Little syndrome. 61
27846944 2016
36
Lupus tumidus: a report of two cases. 61
28300905 2016
37
Cutaneous sarcoidosis masquerading as chronic cutaneous lupus erythematosus - case report. 61
27646659 2016
38
CD123 immunohistochemistry for plasmacytoid dendritic cells is useful in the diagnosis of scarring alopecia. 61
27130548 2016
39
Linear cutaneous lupus erythematosus following the lines of Blaschko - Case report. 61
27579750 2016
40
Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem. 61
26762262 2016
41
Lupus Panniculitis as an Initial Manifestation of Systemic Lupus Erythematosus: A Case Report. 61
27100438 2016
42
Differentiation of Jessner's Lymphocytic Infiltration of the Skin from Various Chronic Cutaneous Lupus Erythematosus Subtypes by Quantitative Computer-Aided Image Analysis. 61
26458204 2016
43
Blisters and Loss of Epidermis in Patients With Lupus Erythematosus: A Clinicopathological Study of 22 Patients. 61
26579826 2015
44
Magnetic resonance imaging findings are useful for evaluating the three-dimensional development and follow-up of linear lupus erythematosus profundus. 61
25716419 2015
45
Treatment of Scarring Alopecia in Discoid Variant of Chronic Cutaneous Lupus Erythematosus With Tacrolimus Lotion, 0.3. 61
26039539 2015
46
Genome-wide transcriptional profiling data from skin of chronic cutaneous lupus erythematosus (CCLE) patients. 61
26217761 2015
47
Brief report: responses to rituximab suggest B cell-independent inflammation in cutaneous systemic lupus erythematosus. 61
25707733 2015
48
Cutaneous lupus erythematosus in skin of color. 61
25844606 2015
49
Genome-wide transcriptional profiling data from chronic cutaneous lupus erythematosus (CCLE) peripheral blood. 61
26217703 2015
50
Genome-wide transcriptional profiling of chronic cutaneous lupus erythematosus (CCLE) peripheral blood identifies systemic alterations relevant to the skin manifestation. 61
25451738 2015

Variations for Chronic Cutaneous Lupus Erythematosus

Expression for Chronic Cutaneous Lupus Erythematosus

Search GEO for disease gene expression data for Chronic Cutaneous Lupus Erythematosus.

Pathways for Chronic Cutaneous Lupus Erythematosus

GO Terms for Chronic Cutaneous Lupus Erythematosus

Sources for Chronic Cutaneous Lupus Erythematosus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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