MCID: CHR692
MIFTS: 20

Chronic Encephalitis

Categories: Immune diseases, Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Chronic Encephalitis

MalaCards integrated aliases for Chronic Encephalitis:

Name: Chronic Encephalitis 58

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Orphanet 58 ORPHA98255

Summaries for Chronic Encephalitis

MalaCards based summary : Chronic Encephalitis is related to encephalitis and epilepsy. The drugs Tacrolimus and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and temporal lobe.

Related Diseases for Chronic Encephalitis

Diseases in the Encephalitis family:

Viral Encephalitis Autoimmune Encephalitis
Chronic Encephalitis Infectious Encephalitis

Diseases related to Chronic Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 encephalitis 10.5
2 epilepsy 10.0
3 focal epilepsy 10.0
4 herpes simplex 9.9
5 spinal arachnoiditis 9.8
6 mumps 9.8
7 arachnoiditis 9.8
8 combined t cell and b cell immunodeficiency 9.8
9 measles 9.8
10 rubella 9.8
11 encephalopathy 9.8
12 alcohol dependence 9.7
13 external auditory canal, bilateral atresia of, with congenital vertical talus 9.7
14 immune deficiency disease 9.7
15 subacute sclerosing panencephalitis 9.7
16 kearns-sayre syndrome 9.7
17 yemenite deaf-blind hypopigmentation syndrome 9.7
18 apraxia of eyelid opening 9.7
19 polymicrogyria with or without vascular-type ehlers-danlos syndrome 9.7
20 apraxia 9.7
21 hemiplegia 9.7
22 rabies 9.7
23 visual epilepsy 9.7
24 optic neuritis 9.7
25 uveitis 9.7
26 neuritis 9.7
27 encephalomalacia 9.7
28 temporal lobe epilepsy 9.7
29 poliomyelitis 9.7
30 von economo's disease 9.7
31 severe combined immunodeficiency 9.7
32 acquired immunodeficiency syndrome 9.7
33 viral encephalitis 9.7
34 vasculitis 9.7
35 chickenpox 9.7
36 amyloidosis 9.7
37 hypereosinophilic syndrome 9.7
38 polymicrogyria 9.7
39 48,xyyy 9.7
40 eales disease 9.7
41 gigantism 9.7
42 glioma 9.7
43 hemimegalencephaly 9.7
44 rasmussen johnsen thomsen syndrome 9.7
45 cerebral atrophy 9.7
46 headache 9.7
47 seizure disorder 9.7
48 spasticity 9.7
49 glial tumor 9.7
50 rasmussen subacute encephalitis 9.7

Graphical network of the top 20 diseases related to Chronic Encephalitis:



Diseases related to Chronic Encephalitis

Symptoms & Phenotypes for Chronic Encephalitis

Drugs & Therapeutics for Chronic Encephalitis

Drugs for Chronic Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tacrolimus Approved, Investigational Phase 2, Phase 3 104987-11-3 445643 439492 6473866
2 Antibodies Phase 2, Phase 3
3 Immunoglobulins Phase 2, Phase 3
4 Immunoglobulins, Intravenous Phase 2, Phase 3
5 Rho(D) Immune Globulin Phase 2, Phase 3
6 Immunosuppressive Agents Phase 2, Phase 3
7 gamma-Globulins Phase 2, Phase 3
8 Calcineurin Inhibitors Phase 2, Phase 3
9 Immunologic Factors Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Efficacy of Tacrolimus and i.v.-Immunoglobulins in Rasmussen Encephalitis With Start of Treatment in the Acute Disease Stage. Prospective, Randomised, Open Parallel Group Study Unknown status NCT00545493 Phase 2, Phase 3 Tacrolimus;i.v. immunoglobulins

Search NIH Clinical Center for Chronic Encephalitis

Genetic Tests for Chronic Encephalitis

Anatomical Context for Chronic Encephalitis

MalaCards organs/tissues related to Chronic Encephalitis:

40
Brain, Bone, Temporal Lobe, Bone Marrow, Myeloid, Occipital Lobe, Hypothalamus

Publications for Chronic Encephalitis

Articles related to Chronic Encephalitis:

(show top 50) (show all 139)
# Title Authors PMID Year
1
Unilateral pallidal stimulation for disabling dystonia due to Rasmussen's disease. 61
29986904 2019
2
Functional neuroimaging in Rasmussen syndrome. 61
29331846 2018
3
Encephalitis, Mild Encephalitis, Neuroprogression, or Encephalopathy-Not Merely a Question of Terminology. 61
30787887 2018
4
Epilepsy surgery for epileptic encephalopathy as a sequela of herpes simplex encephalitis: case report. 61
28452654 2017
5
Nonstructural Protein L* Species Specificity Supports a Mouse Origin for Vilyuisk Human Encephalitis Virus. 61
28446680 2017
6
Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis. 61
27770235 2017
7
Treatment of Chronic Enterovirus Encephalitis With Fluoxetine in a Patient With X-Linked Agammaglobulinemia. 61
27640319 2016
8
Cetacean morbillivirus: current knowledge and future directions. 61
25533660 2014
9
Chronic herpes simplex virus type 2 encephalitis associated with posterior uveitis. 61
24695656 2014
10
Childhood-onset nonprogressive chronic encephalitis. 61
24368410 2014
11
[Expression and clinical significance of tumor necrosis factor-alpha and its receptors in non-specific chronic encephalitis and non-encephalitis relative intractable epilepsy]. 61
24417991 2013
12
Early muscle and brain ultrastructural changes in polymerase gamma 1-related encephalomyopathy. 61
22537151 2013
13
Neuro-ophthalmology of subacute sclerosing panencephalitis: two cases and a review of the literature. 61
23047165 2012
14
Subacute sclerosing panencephalitis with bilateral inferior collicular hyperintensity on magnetic resonance imaging brain. 61
23349608 2012
15
Neuronal gp130 expression is crucial to prevent neuronal loss, hyperinflammation, and lethal course of murine Toxoplasma encephalitis. 61
22640806 2012
16
The myeloid receptor PILR╬▓ mediates the balance of inflammatory responses through regulation of IL-27 production. 61
22479310 2012
17
Chronic granulomatous herpes encephalitis in a child with clinically intractable epilepsy. 61
22919528 2012
18
Pulmonary lymphomatoid granulomatosis in Griscelli syndrome type 2. 61
22111599 2011
19
Viruses and multiple sclerosis. 61
22130640 2011
20
Glutamate excitotoxicity is involved in the induction of paralysis in mice after infection by a human coronavirus with a single point mutation in its spike protein. 61
21957311 2011
21
Early treatment of a progressive Rasmussen's like syndrome with ganciclovir. 61
21320836 2011
22
Kozhevnikov epilepsy: the disease and its eponym. 61
21204824 2011
23
[Spectrum of primary immunodeficiencies in a tertiary hospital over a period of 10 years]. 61
21168377 2011
24
Subacute sclerosing panencephalitis: an update. 61
20561004 2010
25
Mutations in the spike glycoprotein of human coronavirus OC43 modulate disease in BALB/c mice from encephalitis to flaccid paralysis and demyelination. 61
20642316 2010
26
Sequential analysis of fMRI images: A new approach to study human epileptic networks. 61
19490031 2009
27
A medical overview of encephalitis. 61
17676529 2007
28
Refractory occipital lobe epilepsy treated by surgery in a child with chronic encephalitis. 61
17337926 2007
29
Subacute sclerosing panencephalitis presenting as acute disseminated encephalomyelitis. 61
17202644 2006
30
A possible variant of neuro-Behçet disease presenting chronic progressive ataxia without mucocutaneo-ocular symptoms. 61
16932965 2006
31
Early onset Rasmussen's syndrome: a malignant, often bilateral form of the disorder. 61
16822651 2006
32
Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice. 61
16527322 2006
33
Development of anaplastic ependymoma in Rasmussen's encephalitis: review of the literature and case report. 61
15928965 2006
34
Probable chronic viral encephalitis with microglial nodules in the entire brain: a case report with necropsy. 61
15874892 2005
35
Severe and progressive encephalitis as a presenting manifestation of a novel missense perforin mutation and impaired cytolytic activity. 61
15598808 2005
36
October 2002: 27-year-old female with epilepsy. 61
12744477 2003
37
Theodore Brown Rasmussen (1910-2002): epilepsy surgeon, scientist, and teacher. 61
12650440 2003
38
Diagnostic imaging in 13 cases of Rasmussen's encephalitis: can early MRI suggest the diagnosis? 61
12684722 2003
39
Tick-borne flaviviruses. 61
14714436 2003
40
Varicella-zoster virus: atypical presentations and unusual complications. 61
12353193 2002
41
Outbreak of enteroviral infection in a pediatric hematology-oncology unit. 61
11941555 2002
42
Patterns of cerebral glucose metabolism in early and late stages of Rasmussen's syndrome. 61
11732764 2001
43
Glial fibrillary acidic protein (GFAP)-immunoreactive astrocytes in dogs infected with canine distemper virus. 61
11578123 2001
44
Rasmussen's syndrome: intractable epilepsy and progressive neurological deterioration from a unilateral central nervous system. 61
15999028 2001
45
Chronic encephalitis and temporal lobe epilepsy: a variant of Rasmussen's syndrome? 61
11245727 2001
46
Rolandic encephalopathy and epilepsia partialis continua following bone marrow transplant. 61
11081396 2000
47
Differential expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in chronic murine retroviral encephalitis. 61
10931366 2000
48
Comparison of immunoglobulin G heavy-chain sequences in MS and SSPE brains reveals an antigen-driven response. 61
10746589 2000
49
Cloning the antibody response in humans with chronic inflammatory disease: immunopanning of subacute sclerosing panencephalitis (SSPE) brain sections with antibody phage libraries prepared from SSPE brain enriches for antibody recognizing measles virus antigens in situ. 61
10627565 2000
50
[Probable Rasmussen's syndrome. Case report]. 61
10683699 1999

Variations for Chronic Encephalitis

Expression for Chronic Encephalitis

Search GEO for disease gene expression data for Chronic Encephalitis.

Pathways for Chronic Encephalitis

GO Terms for Chronic Encephalitis

Sources for Chronic Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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