MCID: CHR692
MIFTS: 20

Chronic Encephalitis

Categories: Immune diseases, Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Chronic Encephalitis

MalaCards integrated aliases for Chronic Encephalitis:

Name: Chronic Encephalitis 58

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Orphanet 58 ORPHA98255

Summaries for Chronic Encephalitis

MalaCards based summary : Chronic Encephalitis is related to encephalitis and epilepsy. The drugs Tacrolimus and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and temporal lobe.

Related Diseases for Chronic Encephalitis

Diseases in the Encephalitis family:

Viral Encephalitis Autoimmune Encephalitis
Chronic Encephalitis Infectious Encephalitis

Diseases related to Chronic Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 50, show less)
# Related Disease Score Top Affiliating Genes
1 encephalitis 10.5
2 epilepsy 10.0
3 focal epilepsy 10.0
4 herpes simplex 9.9
5 spinal arachnoiditis 9.8
6 mumps 9.8
7 arachnoiditis 9.8
8 combined t cell and b cell immunodeficiency 9.8
9 measles 9.8
10 rubella 9.8
11 encephalopathy 9.8
12 alcohol dependence 9.7
13 external auditory canal, bilateral atresia of, with congenital vertical talus 9.7
14 immune deficiency disease 9.7
15 subacute sclerosing panencephalitis 9.7
16 kearns-sayre syndrome 9.7
17 yemenite deaf-blind hypopigmentation syndrome 9.7
18 apraxia of eyelid opening 9.7
19 polymicrogyria with or without vascular-type ehlers-danlos syndrome 9.7
20 apraxia 9.7
21 hemiplegia 9.7
22 rabies 9.7
23 visual epilepsy 9.7
24 optic neuritis 9.7
25 uveitis 9.7
26 neuritis 9.7
27 encephalomalacia 9.7
28 temporal lobe epilepsy 9.7
29 poliomyelitis 9.7
30 von economo's disease 9.7
31 severe combined immunodeficiency 9.7
32 acquired immunodeficiency syndrome 9.7
33 viral encephalitis 9.7
34 vasculitis 9.7
35 chickenpox 9.7
36 amyloidosis 9.7
37 hypereosinophilic syndrome 9.7
38 polymicrogyria 9.7
39 48,xyyy 9.7
40 eales disease 9.7
41 gigantism 9.7
42 glioma 9.7
43 hemimegalencephaly 9.7
44 rasmussen johnsen thomsen syndrome 9.7
45 cerebral atrophy 9.7
46 headache 9.7
47 seizure disorder 9.7
48 spasticity 9.7
49 glial tumor 9.7
50 rasmussen subacute encephalitis 9.7

Graphical network of the top 20 diseases related to Chronic Encephalitis:



Diseases related to Chronic Encephalitis

Symptoms & Phenotypes for Chronic Encephalitis

Drugs & Therapeutics for Chronic Encephalitis

Drugs for Chronic Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 9, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tacrolimus Approved, Investigational Phase 2, Phase 3 104987-11-3 445643 439492 6473866
2 Antibodies Phase 2, Phase 3
3 Immunoglobulins Phase 2, Phase 3
4 Immunoglobulins, Intravenous Phase 2, Phase 3
5 Rho(D) Immune Globulin Phase 2, Phase 3
6 Immunosuppressive Agents Phase 2, Phase 3
7 gamma-Globulins Phase 2, Phase 3
8 Calcineurin Inhibitors Phase 2, Phase 3
9 Immunologic Factors Phase 2, Phase 3

Interventional clinical trials:

(showing 1, show less)
# Name Status NCT ID Phase Drugs
1 Efficacy of Tacrolimus and i.v.-Immunoglobulins in Rasmussen Encephalitis With Start of Treatment in the Acute Disease Stage. Prospective, Randomised, Open Parallel Group Study Unknown status NCT00545493 Phase 2, Phase 3 Tacrolimus;i.v. immunoglobulins

Search NIH Clinical Center for Chronic Encephalitis

Genetic Tests for Chronic Encephalitis

Anatomical Context for Chronic Encephalitis

MalaCards organs/tissues related to Chronic Encephalitis:

40
Brain, Bone, Temporal Lobe, Bone Marrow, Myeloid, Occipital Lobe, Hypothalamus

Publications for Chronic Encephalitis

Articles related to Chronic Encephalitis:

(showing 139, show less)
# Title Authors PMID Year
1
Unilateral pallidal stimulation for disabling dystonia due to Rasmussen's disease. 61
29986904 2019
2
Functional neuroimaging in Rasmussen syndrome. 61
29331846 2018
3
Encephalitis, Mild Encephalitis, Neuroprogression, or Encephalopathy-Not Merely a Question of Terminology. 61
30787887 2018
4
Epilepsy surgery for epileptic encephalopathy as a sequela of herpes simplex encephalitis: case report. 61
28452654 2017
5
Nonstructural Protein L* Species Specificity Supports a Mouse Origin for Vilyuisk Human Encephalitis Virus. 61
28446680 2017
6
Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis. 61
27770235 2017
7
Treatment of Chronic Enterovirus Encephalitis With Fluoxetine in a Patient With X-Linked Agammaglobulinemia. 61
27640319 2016
8
Cetacean morbillivirus: current knowledge and future directions. 61
25533660 2014
9
Chronic herpes simplex virus type 2 encephalitis associated with posterior uveitis. 61
24695656 2014
10
Childhood-onset nonprogressive chronic encephalitis. 61
24368410 2014
11
[Expression and clinical significance of tumor necrosis factor-alpha and its receptors in non-specific chronic encephalitis and non-encephalitis relative intractable epilepsy]. 61
24417991 2013
12
Early muscle and brain ultrastructural changes in polymerase gamma 1-related encephalomyopathy. 61
22537151 2013
13
Neuro-ophthalmology of subacute sclerosing panencephalitis: two cases and a review of the literature. 61
23047165 2012
14
Subacute sclerosing panencephalitis with bilateral inferior collicular hyperintensity on magnetic resonance imaging brain. 61
23349608 2012
15
Neuronal gp130 expression is crucial to prevent neuronal loss, hyperinflammation, and lethal course of murine Toxoplasma encephalitis. 61
22640806 2012
16
The myeloid receptor PILR╬▓ mediates the balance of inflammatory responses through regulation of IL-27 production. 61
22479310 2012
17
Chronic granulomatous herpes encephalitis in a child with clinically intractable epilepsy. 61
22919528 2012
18
Pulmonary lymphomatoid granulomatosis in Griscelli syndrome type 2. 61
22111599 2011
19
Viruses and multiple sclerosis. 61
22130640 2011
20
Glutamate excitotoxicity is involved in the induction of paralysis in mice after infection by a human coronavirus with a single point mutation in its spike protein. 61
21957311 2011
21
Early treatment of a progressive Rasmussen's like syndrome with ganciclovir. 61
21320836 2011
22
Kozhevnikov epilepsy: the disease and its eponym. 61
21204824 2011
23
[Spectrum of primary immunodeficiencies in a tertiary hospital over a period of 10 years]. 61
21168377 2011
24
Subacute sclerosing panencephalitis: an update. 61
20561004 2010
25
Mutations in the spike glycoprotein of human coronavirus OC43 modulate disease in BALB/c mice from encephalitis to flaccid paralysis and demyelination. 61
20642316 2010
26
Sequential analysis of fMRI images: A new approach to study human epileptic networks. 61
19490031 2009
27
A medical overview of encephalitis. 61
17676529 2007
28
Refractory occipital lobe epilepsy treated by surgery in a child with chronic encephalitis. 61
17337926 2007
29
Subacute sclerosing panencephalitis presenting as acute disseminated encephalomyelitis. 61
17202644 2006
30
A possible variant of neuro-Behçet disease presenting chronic progressive ataxia without mucocutaneo-ocular symptoms. 61
16932965 2006
31
Early onset Rasmussen's syndrome: a malignant, often bilateral form of the disorder. 61
16822651 2006
32
Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice. 61
16527322 2006
33
Development of anaplastic ependymoma in Rasmussen's encephalitis: review of the literature and case report. 61
15928965 2006
34
Probable chronic viral encephalitis with microglial nodules in the entire brain: a case report with necropsy. 61
15874892 2005
35
Severe and progressive encephalitis as a presenting manifestation of a novel missense perforin mutation and impaired cytolytic activity. 61
15598808 2005
36
October 2002: 27-year-old female with epilepsy. 61
12744477 2003
37
Theodore Brown Rasmussen (1910-2002): epilepsy surgeon, scientist, and teacher. 61
12650440 2003
38
Diagnostic imaging in 13 cases of Rasmussen's encephalitis: can early MRI suggest the diagnosis? 61
12684722 2003
39
Tick-borne flaviviruses. 61
14714436 2003
40
Varicella-zoster virus: atypical presentations and unusual complications. 61
12353193 2002
41
Outbreak of enteroviral infection in a pediatric hematology-oncology unit. 61
11941555 2002
42
Patterns of cerebral glucose metabolism in early and late stages of Rasmussen's syndrome. 61
11732764 2001
43
Glial fibrillary acidic protein (GFAP)-immunoreactive astrocytes in dogs infected with canine distemper virus. 61
11578123 2001
44
Rasmussen's syndrome: intractable epilepsy and progressive neurological deterioration from a unilateral central nervous system. 61
15999028 2001
45
Chronic encephalitis and temporal lobe epilepsy: a variant of Rasmussen's syndrome? 61
11245727 2001
46
Rolandic encephalopathy and epilepsia partialis continua following bone marrow transplant. 61
11081396 2000
47
Differential expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in chronic murine retroviral encephalitis. 61
10931366 2000
48
Comparison of immunoglobulin G heavy-chain sequences in MS and SSPE brains reveals an antigen-driven response. 61
10746589 2000
49
Cloning the antibody response in humans with chronic inflammatory disease: immunopanning of subacute sclerosing panencephalitis (SSPE) brain sections with antibody phage libraries prepared from SSPE brain enriches for antibody recognizing measles virus antigens in situ. 61
10627565 2000
50
[Probable Rasmussen's syndrome. Case report]. 61
10683699 1999
51
The CD28/B7 interaction is not required for resistance to Toxoplasma gondii in the brain but contributes to the development of immunopathology. 61
10477605 1999
52
Histopathologic findings in 37 cases of functional hemispherectomy. 61
10459046 1999
53
[Effect of gentamycin on persistence of tick-borne encephalitis]. 61
10190241 1999
54
Chronic active destructive herpes simplex encephalitis with recovery of viral DNA 12 years after disease onset. 61
9706620 1998
55
Familial alternating epilepsia partialis continua with chronic encephalitis: another variant of Rasmussen syndrome? 61
9605733 1998
56
Double pathology in Rasmussen's syndrome: a window on the etiology? 61
9521265 1998
57
Intractable seizure disorder associated with chronic herpes infection. HSV1 detection in tissue by the polymerase chain reaction. 61
9548334 1998
58
[A case of chronic encephalitis due to double infection with herpes simplex and measles viruses]. 61
9396034 1997
59
[Central nervous system infection caused by mumps virus]. 61
9103886 1997
60
Chronic encephalitis and epilepsy in adults and adolescents: a variant of Rasmussen's syndrome? 61
9040732 1997
61
Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen. 61
9013988 1997
62
[EEG anomalies in the prodromic phase of Rasmussen's syndrome. Report of two cases]. 61
9206756 1997
63
Coexistence of hemimegalencephaly and chronic encephalitis. Detection of cytomegalovirus by the polymerase chain reaction. 61
9083700 1997
64
Treatment of Rasmussen's syndrome with ganciclovir. 61
8857720 1996
65
Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper virus encephalitis. 61
8870829 1996
66
Chronic steroid-responsive encephalitis without autoantibodies to glutamate receptor GluR3. 61
8559386 1996
67
Blood-brain barrier damage in children with central nervous system infections. 61
7549573 1995
68
Rasmussen's syndrome: a study of potential viral etiology. 61
7729084 1995
69
Pathology of chronic herpes infection associated with seizure disorder: a report of two cases with tissue detection of herpes simplex virus 1 by the polymerase chain reaction. 61
8736603 1995
70
Chronic encephalitis and epilepsy (Rasmussen's encephalitis): detection of cytomegalovirus and herpes simplex virus 1 by the polymerase chain reaction and in situ hybridization. 61
7824098 1995
71
Chronic encephalitis associated with epilepsy: immunohistochemical and ultrastructural studies. 61
7610762 1995
72
Medical treatment of Rasmussen's syndrome (chronic encephalitis and epilepsy): effect of high-dose steroids or immunoglobulins in 19 patients. 61
8208394 1994
73
[Psychoses in encephalitis of uncertain etiology. Atypical course of multiple sclerosis?]. 61
8177356 1994
74
Autoptic findings in HIV-1 positive children. 61
8152206 1994
75
Free-living amebas of the genera Acanthamoeba and Naegleria: an overview and basic microbiologic correlates. 61
8232368 1993
76
Brain structures selectively targeted by canine distemper virus in a mouse model infection. 61
8360700 1993
77
Herpesviruses in chronic encephalitis associated with intractable childhood epilepsy. 61
8397159 1993
78
Chronic encephalitis and Eales disease. 61
8326335 1993
79
Rasmussen's chronic encephalitis in adults. 61
8382920 1993
80
Functional hemispherectomy in children. 61
8474613 1993
81
Chronic encephalitis (Rasmussen's syndrome) and ipsilateral uveitis. 61
1471877 1992
82
Expression of major histocompatibility complex antigens in the brains of patients with progressive multifocal leukoencephalopathy. 61
1583532 1992
83
The syndrome of chronic encephalitis and epilepsy. A study based on the MNI series of 48 cases. 61
1543071 1992
84
Epilepsia partialis continua studied by PET. 61
1909238 1991
85
Expression of major histocompatibility complex and HIV antigens within the brains of AIDS patients. 61
1863405 1991
86
Rasmussen encephalitis: epilepsia partialis continua secondary to chronic encephalitis. 61
2127355 1990
87
Chronic encephalitis caused by leukoencephalopathy. 61
2228661 1990
88
Chronic encephalitis, epilepsy, and cerebrovascular immune complex deposits. 61
2375639 1990
89
Immunohistochemical localization of prion protein in spongiform encephalopathies and normal brain tissue. 61
1690364 1990
90
[Chronic encephalitis with mesencephalic predominance. A clinico-pathologic case]. 61
2399410 1990
91
Astrocytic reaction predominance in chronic encephalitis of Junin virus-infected rats. 61
2559956 1989
92
Update on the syndrome of "chronic encephalitis" and epilepsy. 61
2499429 1989
93
Chronic progressive varicella-zoster virus encephalitis in an AIDS patient. 61
2838767 1988
94
Immunologic studies of patients with chronic encephalitis induced by post-exposure Semple rabies vaccine. 61
2447520 1988
95
Neuropathology and neurovirulence of canine distemper virus plaque isolates in the hamster. 61
3683747 1987
96
[Unusual course of necrotizing encephalitis]. 61
3685208 1987
97
[An unusual cerebrovascular amyloidosis simulating chronic encephalitis]. 61
3110637 1987
98
Cranial magnetic resonance imaging in multiple sclerosis--indicated only in exceptional cases? 61
3506141 1987
99
[Chronic encephalitis caused by mumps virus]. 61
3522189 1986
100
Chronic encephalitis possibly due to herpes simplex virus: two cases. 61
4033928 1985
101
Encephalitis induced in non-human primates by canine distemper virus adapted to human neural cells. 61
4087464 1985
102
[Etiology, pathogenesis, clinical picture and treatment of spastic torticollis and other extrapyramidal hyperkinesis]. 61
4090833 1985
103
Persistence of tick-borne encephalitis virus in monkeys. VI. Pathomorphology of chronic infection in central nervous system. 61
6148000 1984
104
Pathogenesis of Borna disease in rats: immune-mediated viral ophthalmoencephalopathy causing blindness and behavioral abnormalities. 61
6604114 1983
105
[Jakob-Creutzfeldt disease]. 61
6354480 1983
106
Behavioral disease in rats caused by immunopathological responses to persistent borna virus in the brain. 61
6602380 1983
107
Postictal blindness in adults. 61
6410006 1983
108
Naegleria australiensis: experimental meningoencephalitis in mice. 61
6659050 1983
109
Persistence of tick-borne encephalitis virus IV. Virus localization after intracerebral inoculation. 61
6128904 1982
110
[Characteristics of long-term persisting strains of tick-borne encephalitis virus in different forms of the chronic process in animals]. 61
6753337 1982
111
Differentiation of the humoral immune response in inflammatory diseases of the central nervous system. 61
6188810 1982
112
[Importance of morphologic examination of a focus of viral infection in the brain to evaluation of the possible development of chronic encephalitis]. 61
7124221 1982
113
Persistence of tick-borne encephalitis virus in monkeys. I. Features of experimental infection. 61
6120634 1981
114
Chronic encephalitis in X-linked agammaglobulinaemia. 61
6939224 1981
115
Chronic measles encephalitis in mice. 61
7441020 1980
116
[Progressive chronic encephalitis of rubella. Apropos of a case]. 61
7224540 1980
117
Further observations on the syndrome of chronic encephalitis and epilepsy. 61
103497 1978
118
[Clinical and histopathological studies of cases of lafora-like inclusion bodies]. 61
193769 1977
119
[Pathogenetic mechanisms of tick-borne encephalitis]. 61
402756 1977
120
Age-related susceptibility to infection with canine distemper virus in gnotobiotic dogs. 61
1003016 1976
121
[Basic principles of work capacity evaluation of patients with vestibular disorders in chronic encephalitis and arachnoiditis]. 61
1020161 1976
122
[Arterial oscillography in the clinical evaluation of vestibular disorders in chronic encephalitis and cerebral arachnoiditis]. 61
1083606 1976
123
[Case of chronic encephalitis with Coxsackie A 5 virus isolated from the cerebrospinal fluid]. 61
4477054 1974
124
Combined immunodeficiency and chronic encephalitis. 61
4102874 1971
125
Chronic encephalitis in children with severe immuno-deficiency. 61
5134159 1971
126
[Chronic encephalitis. Predominance of lesions in the striate nuclei and brain stem. Anatomical and clinical study. Discussion on etiology]. 61
5343626 1969
127
Clinical studies of patients with focal epilepsy due to "chronic encephalitis". 61
4974863 1968
128
[Chronic encephalitis with diffuse anatomical necroses; particular form of scleronisant leukoencephalitis with prolonged evolution]. 61
6004669 1966
129
Atypical chronic encephalitis of later adult life with multifocal demyelination and eosinophilia. 61
6004675 1966
130
[A CASE OF CHRONIC ENCEPHALITIS WITH PSYCHOTIC SYMPTOMS]. 61
14249564 1964
131
[C-reactive protein in chronic encephalitis]. 61
13689485 1960
132
Glioma of hypothalamus simulating chronic encephalitis; report of case. 61
13396436 1956
133
[Ophthalmic symptoms in chronic encephalitis with calcification of the brain]. 61
14929517 1952
134
[Conditioned reactions in the treatment with atropine of chronic encephalitis and of chronic alcoholism]. 61
12995967 1951
135
[Oculogyric crises associated with paroxysmal bulimia in chronic encephalitis]. 61
15441957 1950
136
A clinico-pathological report on unusual cases of chronic encephalitis. 61
20265612 1947
137
A Microscopical Inquiry into the Ætiology of Poliomyelitis with a Note on Chronic Encephalitis Lethargica. 61
29646812 1939
138
Medicine: The Stramonium Treatment of Chronic Encephalitis. 61
18741285 1930
139
(?) Chronic Encephalitis. 61
19975475 1911

Variations for Chronic Encephalitis

Expression for Chronic Encephalitis

Search GEO for disease gene expression data for Chronic Encephalitis.

Pathways for Chronic Encephalitis

GO Terms for Chronic Encephalitis

Sources for Chronic Encephalitis

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68 SNOMED-CT via HPO
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70 Tocris
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72 UMLS via Orphanet
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