MCID: CHR280
MIFTS: 30

Chronic Erosive Gastritis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Chronic Erosive Gastritis

MalaCards integrated aliases for Chronic Erosive Gastritis:

Name: Chronic Erosive Gastritis 54 74
Idiopathic Chronic, Erosive Gastritis 54
Varioliform Gastritis 54

Classifications:



External Ids:

UMLS 74 C0267145

Summaries for Chronic Erosive Gastritis

MalaCards based summary : Chronic Erosive Gastritis, also known as idiopathic chronic, erosive gastritis, is related to gastritis and lymphocytic gastritis. An important gene associated with Chronic Erosive Gastritis is HGF (Hepatocyte Growth Factor), and among its related pathways/superpathways are Pathways in cancer and MAPK signaling pathway. The drugs Sucralfate and Antacids have been mentioned in the context of this disorder. Affiliated tissues include small intestine, lung and thyroid.

Wikipedia : 77 Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, first part of the small... more...

Related Diseases for Chronic Erosive Gastritis

Graphical network of the top 20 diseases related to Chronic Erosive Gastritis:



Diseases related to Chronic Erosive Gastritis

Symptoms & Phenotypes for Chronic Erosive Gastritis

Drugs & Therapeutics for Chronic Erosive Gastritis

Drugs for Chronic Erosive Gastritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sucralfate Approved Phase 4 54182-58-0
2 Antacids Phase 4
3 Anti-Ulcer Agents Phase 4
4 Gastrointestinal Agents Phase 4
5 Geranylgeranylacetone Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Study to Evaluate the Efficacy of Teprenone On Chinese Patients With Chronic Non-Atrophic Erosive Gastritis Completed NCT01284647 Phase 4 Teprenone capsule and placebo of sucralfate;Sucralfate and placebo of teprenone

Search NIH Clinical Center for Chronic Erosive Gastritis

Genetic Tests for Chronic Erosive Gastritis

Anatomical Context for Chronic Erosive Gastritis

MalaCards organs/tissues related to Chronic Erosive Gastritis:

42
Small Intestine, Lung, Thyroid, Salivary Gland

Publications for Chronic Erosive Gastritis

Articles related to Chronic Erosive Gastritis:

(show all 18)
# Title Authors Year
1
[Correlation Research on HGF and c-Met of Chronic Erosive Gastritis Patients]. ( 30650495 )
2017
2
Gastro-protecting effect of gefarnate on chronic erosive gastritis with dyspeptic symptoms. ( 22932084 )
2012
3
Anti-inflammatory effects of rebamipide according to Helicobacter pylori status in patients with chronic erosive gastritis: a randomized sucralfate-controlled multicenter trial in China-STARS study. ( 18288617 )
2008
4
Study on clinical pathology and immunohistochemistry of chronic erosive gastritis. ( 27041963 )
1997
5
Misoprostol for the treatment of chronic erosive gastritis: a double-blind placebo-controlled trial. ( 8017357 )
1994
6
Chronic erosive gastritis on morphological analysis. ( 8062065 )
1994
7
Preventive effect of cimetidine on chronic erosive gastritis induced by taurocholate in rats. ( 2024066 )
1991
8
Treatment of established taurocholate-induced chronic erosive gastritis in rats with cimetidine. ( 2047573 )
1991
9
Treatment of chronic erosive gastritis: a double-blind trial of pirenzepine and cimetidine. ( 2692820 )
1989
10
Chronic erosive gastritis--a therapeutic approach with bismuth. ( 3166538 )
1988
11
Chronic erosive gastritis: a clinical study. ( 3565332 )
1987
12
Chronic erosive gastritis--a recently recognized disorder. ( 6822183 )
1983
13
Chronic erosive gastritis resulting in cachexia. ( 6839651 )
1983
14
Chronic erosive gastritis--clinical and radiological features. ( 6292231 )
1982
15
Chronic erosive gastritis: clinical, diagnostic, and pathological features in nine patients. ( 7102635 )
1982
16
Chronic erosive gastritis. ( 7161586 )
1982
17
Treatment of chronic erosive gastritis with prednisolone. ( 7297926 )
1981
18
Gastritis varioliformis. Chronic erosive gastritis with protein-losing gastropathy. ( 612216 )
1977

Variations for Chronic Erosive Gastritis

Expression for Chronic Erosive Gastritis

Search GEO for disease gene expression data for Chronic Erosive Gastritis.

Pathways for Chronic Erosive Gastritis

Pathways related to Chronic Erosive Gastritis according to GeneCards Suite gene sharing:

(show all 27)
# Super pathways Score Top Affiliating Genes
1 12.35 HGF MET
2 12.28 HGF MET
3
Show member pathways
12.27 HGF MET
4
Show member pathways
12.24 HGF MET
5
Show member pathways
12.23 HGF MET
6
Show member pathways
12.21 HGF MET
7
Show member pathways
12.21 HGF MET
8
Show member pathways
12.2 HGF MET
9
Show member pathways
12.1 HGF MET
10
Show member pathways
12 HGF MET
11
Show member pathways
11.92 HGF MET
12 11.83 HGF MET
13
Show member pathways
11.77 HGF MET
14 11.6 HGF MET
15
Show member pathways
11.58 HGF MET
16 11.58 HGF MET
17 11.58 HGF MET
18
Show member pathways
11.4 HGF MET
19 11.09 HGF MET
20 11.04 HGF MET
21
Show member pathways
10.94 HGF MET
22 10.89 HGF MET
23 10.86 HGF MET
24 10.69 HGF MET
25 10.54 HGF MET
26 10.43 HGF MET
27 9.85 HGF MET

GO Terms for Chronic Erosive Gastritis

Biological processes related to Chronic Erosive Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.43 HGF MET
2 positive regulation of protein kinase B signaling GO:0051897 9.37 HGF MET
3 liver development GO:0001889 9.32 HGF MET
4 positive chemotaxis GO:0050918 9.26 HGF MET
5 negative regulation of apoptotic process GO:0043066 9.18 HGF
6 cell proliferation GO:0008283 9.16 MET
7 negative regulation of autophagy GO:0010507 9.16 HGF MET
8 peptidyl-tyrosine phosphorylation GO:0018108 9.1 MET
9 hepatocyte growth factor receptor signaling pathway GO:0048012 8.96 HGF MET
10 negative regulation of hydrogen peroxide-mediated programmed cell death GO:1901299 8.62 HGF MET

Molecular functions related to Chronic Erosive Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 8.32 MET

Sources for Chronic Erosive Gastritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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