MCID: CHR280
MIFTS: 28

Chronic Erosive Gastritis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Chronic Erosive Gastritis

MalaCards integrated aliases for Chronic Erosive Gastritis:

Name: Chronic Erosive Gastritis 20 70
Idiopathic Chronic, Erosive Gastritis 20
Varioliform Gastritis 20

Classifications:



External Ids:

UMLS 70 C0267145

Summaries for Chronic Erosive Gastritis

MalaCards based summary : Chronic Erosive Gastritis, also known as idiopathic chronic, erosive gastritis, is related to gastritis and lymphocytic gastritis. An important gene associated with Chronic Erosive Gastritis is HGF (Hepatocyte Growth Factor), and among its related pathways/superpathways are Regulation of lipid metabolism Insulin signaling-generic cascades and Pathways in cancer. The drugs Sucralfate and Antacids have been mentioned in the context of this disorder. Affiliated tissues include small intestine, pancreas and tongue.

Wikipedia : 73 Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small... more...

Related Diseases for Chronic Erosive Gastritis

Diseases related to Chronic Erosive Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 gastritis 10.7
2 lymphocytic gastritis 10.4
3 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.3
4 peptic ulcer disease 10.3
5 gastric ulcer 10.2
6 helicobacter pylori infection 10.2
7 ige responsiveness, atopic 10.0
8 duodenal ulcer 10.0
9 calcinosis 10.0
10 food allergy 10.0
11 papillary adenocarcinoma 10.0
12 liver cirrhosis 10.0
13 atrophic gastritis 10.0
14 duodenitis 10.0
15 gastroduodenitis 10.0
16 doxorubicin induced cardiomyopathy 9.8 MET HGF
17 pediatric hepatocellular carcinoma 9.8 MET HGF
18 familial renal papillary carcinoma 9.8 MET HGF
19 papillary carcinoma 9.8 MET HGF
20 deafness, autosomal recessive 97 9.8 MET HGF
21 papillary thyroid microcarcinoma 9.8 MET HGF
22 large cell medulloblastoma 9.8 MET HGF
23 hereditary renal cell carcinoma 9.8 MET HGF
24 vitreoretinopathy, neovascular inflammatory 9.8 MET HGF
25 mucositis 9.8 MET HGF
26 follicular adenoma 9.8 MET HGF
27 inguinal hernia 9.8 MET HGF
28 microvascular complications of diabetes 1 9.8 MET HGF
29 refractive error 9.8 MET HGF
30 salivary gland carcinoma 9.8 MET HGF
31 sarcoma, synovial 9.8 MET HGF
32 mesothelioma, malignant 9.8 MET HGF
33 renal cell carcinoma, papillary, 1 9.8 MET HGF
34 hepatoblastoma 9.7 MET HGF
35 cholangiocarcinoma 9.7 MET HGF
36 melanoma, uveal 9.7 MET HGF
37 pancreatic adenocarcinoma 9.7 MET HGF
38 adenocarcinoma 9.7 MET HGF
39 skin melanoma 9.6 MET HGF
40 lung cancer susceptibility 3 9.6 MET HGF
41 squamous cell carcinoma, head and neck 9.5 MET HGF

Graphical network of the top 20 diseases related to Chronic Erosive Gastritis:



Diseases related to Chronic Erosive Gastritis

Symptoms & Phenotypes for Chronic Erosive Gastritis

Drugs & Therapeutics for Chronic Erosive Gastritis

Drugs for Chronic Erosive Gastritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sucralfate Approved Phase 4 54182-58-0
2 Antacids Phase 4
3 Anti-Ulcer Agents Phase 4
4 Geranylgeranylacetone Phase 4
5 Gastrointestinal Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Prospective, Randomized, Double-blind, Double-dummy, Sucralfate Controlled, Multicenter Study to Evaluate the Efficacy of Teprenone On Chinese Patients With Chronic Non-Atrophic Erosive Gastritis Completed NCT01284647 Phase 4 Teprenone capsule and placebo of sucralfate;Sucralfate and placebo of teprenone

Search NIH Clinical Center for Chronic Erosive Gastritis

Genetic Tests for Chronic Erosive Gastritis

Anatomical Context for Chronic Erosive Gastritis

MalaCards organs/tissues related to Chronic Erosive Gastritis:

40
Small Intestine, Pancreas, Tongue, Bone, Liver, Lung, Thyroid

Publications for Chronic Erosive Gastritis

Articles related to Chronic Erosive Gastritis:

(show top 50) (show all 103)
# Title Authors PMID Year
1
Varioliform gastritis: an unusual endoscopic finding. 61
29991899 2018
2
[Effect of Huazhuo Jiedu formula on HIF-1α, VEGF, and PTEN in chronic erosive gastritis patients with syndrome of accumulation of turbidity and toxicity]. 61
29945395 2018
3
Comorbid for gastroduodenal ulcers in the aspect of calcium imbalance and blockers of slow calcium channels in their treatment. 61
30701769 2018
4
[Correlation Research on HGF and c-Met of Chronic Erosive Gastritis Patients]. 61
30650495 2017
5
Bacillus as a potential diagnostic marker for yellow tongue coating. 61
27578261 2016
6
[Specific features of the enteric microbiota composition in patients with alcoholic liver cirrhosis]. 61
26978420 2015
7
Calcinosis, varioliform gastritis, and bleeding. 61
24703860 2014
8
Chaihu-Shugan-San, an oriental herbal preparation, for the treatment of chronic gastritis: a meta-analysis of randomized controlled trials. 61
23376045 2013
9
Cap-polyposis-like gastropathy with hypoproteinemia treated with H. pylori eradication. 61
24088754 2013
10
Gastro-protecting effect of gefarnate on chronic erosive gastritis with dyspeptic symptoms. 61
22932084 2012
11
Gastric metaplasia and Helicobacter pylori infection in hemodialysis patients. 61
22250918 2012
12
[Comparative analysis of the serum level of autoantibodies as a diagnostic tool of myocardial inflammatory diseases]. 61
23091853 2012
13
Proteomic analysis reveals molecular biological details in varioliform gastritis without Helicobacter pylori infection. 61
20677338 2010
14
[Association between varioliform gastritis and cirrhosis]. 61
21140051 2010
15
[Ultrastructural changes and regeneration of the endocrine apparatus of the human gastric mucosal glandular epithelium in patients with chronic erosive gastritis]. 61
21513104 2010
16
Anti-inflammatory effects of rebamipide according to Helicobacter pylori status in patients with chronic erosive gastritis: a randomized sucralfate-controlled multicenter trial in China-STARS study. 61
18288617 2008
17
[A rare cause of peripheral edema: exudative lymphocytic gastritis induced hypoprotidemia]. 61
17540312 2007
18
[Lymphocytic gastritis with anasarca and venous thrombosis]. 61
16783256 2006
19
Therapeutic effect of DA-9601 on chronic reflux gastritis induced by sodium taurocholate in rats. 61
16437712 2005
20
Ampullary carcinoma associated with protein-losing gastropathy due to diffuse varioliform gastritis. 61
16001648 2005
21
[Peculiarities of ulcerous and erosive lesions of gastroduodenal zone in patients with arterial hypertension]. 61
15941143 2005
22
[Changes in the local proteinase-inhibitor system in children with chronic erosive gastritis]. 61
11944386 2002
23
[Edematous syndrome revealing an exudative lymphocytic gastritis: efficacy of omeprazole]. 61
11084434 2000
24
[Varioliform gastritis: frequency and relationship with lymphocytic gastritis]. 61
10962621 2000
25
[Intravenous treatment with quamatel in reflux-esophagus and erosive gastritis]. 61
11688330 2000
26
Growth factors in gastrointestinal diseases. 61
18031160 1999
27
Spectrum of gastritis in celiac disease in childhood. 61
10191345 1999
28
Lymphocytic gastritis: association with etiology and topology. 61
9989841 1999
29
Atopy and food allergy in varioliform gastritis. 61
9802466 1998
30
Hypertrophic lymphocytic gastritis with a gastric carcinoma. 61
9831277 1998
31
Hyperplastic foveolar gastropathies and hyperplastic foveolar gastritis. 61
9368593 1997
32
Study on clinical pathology and immunohistochemistry of chronic erosive gastritis. 61
27041963 1997
33
Basic fibroblast growth factor and PDGF in GI diseases. 61
8732303 1996
34
Varioliform gastritis and duodenitis associated with protein-losing gastroenteropathy, treated with omeprazole. 61
8808438 1996
35
[Chronic gastritis and ulcer disease in young men]. 61
9091950 1996
36
Varioliform gastritis - an endoscopic presentation form of Helicobacter pylori. 61
17588999 1995
37
Lymphocytic gastritis. Clinical and endoscopic presentation and long-term follow-up. 61
7571985 1995
38
Growth factors: new 'endogenous drugs' for ulcer healing. 61
8578198 1995
39
Misoprostol for the treatment of chronic erosive gastritis: a double-blind placebo-controlled trial. 61
8017357 1994
40
[Comparative evaluation of sucralfate (Venter) and cimetidine (Altramet) efficiency in treatment of chronic erosive gastritis]. 61
8058972 1994
41
Chronic erosive gastritis on morphological analysis. 61
8062065 1994
42
[Varioliform gastritis or lymphocytic gastritis? Anatomoclinical study. Apropos of 14 cases]. 61
7811112 1994
43
Lymphocytic gastritis: an unusual cause of hypoproteinaemia. 61
8326297 1993
44
Chronic diffuse varioliform gastritis in a child. Total gastrectomy for acute massive bleeding. 61
8421144 1993
45
[Gastric secretion in chronic erosive gastritis]. 61
1438918 1992
46
Hypertrophic gastropathy with gastric adenocarcinoma: Menetrier's disease and lymphocytic gastritis? 61
1773969 1991
47
Ménétrier's disease with lymphocytic gastritis: an unusual association with possible pathogenic implications. 61
2050372 1991
48
Treatment of established taurocholate-induced chronic erosive gastritis in rats with cimetidine. 61
2047573 1991
49
Preventive effect of cimetidine on chronic erosive gastritis induced by taurocholate in rats. 61
2024066 1991
50
[Campylobacter (Helicobacter) pylori in chronic erosive gastritis, duodenitis and gastroduodenitis]. 61
1891906 1991

Variations for Chronic Erosive Gastritis

Expression for Chronic Erosive Gastritis

Search GEO for disease gene expression data for Chronic Erosive Gastritis.

Pathways for Chronic Erosive Gastritis

Pathways related to Chronic Erosive Gastritis according to GeneCards Suite gene sharing:

(show all 29)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.37 MET HGF
2 12.36 MET HGF
3 12.29 MET HGF
4
Show member pathways
12.28 MET HGF
5
Show member pathways
12.26 MET HGF
6
Show member pathways
12.24 MET HGF
7
Show member pathways
12.22 MET HGF
8
Show member pathways
12.21 MET HGF
9
Show member pathways
12.19 MET HGF
10
Show member pathways
12.03 MET HGF
11
Show member pathways
12.02 MET HGF
12 11.93 MET HGF
13
Show member pathways
11.92 MET HGF
14 11.85 MET HGF
15
Show member pathways
11.79 MET HGF
16 11.63 MET HGF
17 11.63 MET HGF
18 11.62 MET HGF
19
Show member pathways
11.44 MET HGF
20 11.3 MET HGF
21 11.13 MET HGF
22 11.08 MET HGF
23 10.97 MET HGF
24 10.88 MET HGF
25 10.79 MET HGF
26 10.63 MET HGF
27 10.55 MET HGF
28 10.19 MET HGF
29
Show member pathways
9.66 MET HGF

GO Terms for Chronic Erosive Gastritis

Biological processes related to Chronic Erosive Gastritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.4 MET HGF
2 positive regulation of protein kinase B signaling GO:0051897 9.37 MET HGF
3 liver development GO:0001889 9.32 MET HGF
4 negative regulation of autophagy GO:0010507 9.26 MET HGF
5 positive chemotaxis GO:0050918 9.16 MET HGF
6 hepatocyte growth factor receptor signaling pathway GO:0048012 8.96 MET HGF
7 negative regulation of hydrogen peroxide-mediated programmed cell death GO:1901299 8.62 MET HGF

Sources for Chronic Erosive Gastritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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