MCID: CHR047
MIFTS: 28

Chronic Ethmoiditis

Categories: Respiratory diseases

Aliases & Classifications for Chronic Ethmoiditis

MalaCards integrated aliases for Chronic Ethmoiditis:

Name: Chronic Ethmoiditis 12 15
Chronic Ethmoidal Sinusitis 12 70 32
Ethmoidal Sinusitis - Chronic 12
Chronic Ethmoid Sinusitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9312
ICD9CM 34 473.2
NCIt 50 C34472
SNOMED-CT 67 155528009
ICD10 32 J32.2
UMLS 70 C0008681

Summaries for Chronic Ethmoiditis

Disease Ontology : 12 A ethmoid sinusitis which lasts for 12 weeks or more.

MalaCards based summary : Chronic Ethmoiditis, also known as chronic ethmoidal sinusitis, is related to ethmoid sinusitis and haemophilus influenzae. An important gene associated with Chronic Ethmoiditis is MUC7 (Mucin 7, Secreted), and among its related pathways/superpathways are Innate Immune System and Metabolism of proteins.

Related Diseases for Chronic Ethmoiditis

Diseases in the Acute Ethmoiditis family:

Chronic Ethmoiditis

Diseases related to Chronic Ethmoiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 ethmoid sinusitis 10.4
2 haemophilus influenzae 10.2
3 chronic maxillary sinusitis 10.1
4 oculomotor nerve paralysis 10.1
5 maxillary sinusitis 10.1
6 third cranial nerve disease 10.1
7 scotoma 10.1
8 dacryocystitis 10.0 MUC7 MUC5AC
9 acute inflammation of lacrimal passage 10.0 MUC7 MUC5AC
10 bacterial infectious disease 10.0
11 chlamydia 10.0
12 gastric tubular adenocarcinoma 10.0 MUC6 MUC5AC
13 ovarian mucinous neoplasm 10.0 MUC6 MUC5AC
14 cap polyposis 10.0 MUC5AC MUC4
15 small intestine adenocarcinoma 10.0 MUC6 MUC5AC
16 duodenum adenocarcinoma 10.0 MUC6 MUC5AC
17 senile ectropion 10.0 MUC5AC MUC4
18 middle ear disease 9.9 MUC5B MUC5AC
19 cystic teratoma 9.9 MUC6 MUC5AC
20 blepharitis 9.9 MUC5AC MUC4
21 interstitial pneumonitis, desquamative, familial 9.9 MUC5B MUC1
22 microinvasive gastric cancer 9.9 MUC6 MUC5AC
23 common cold 9.9 MUC5B MUC5AC
24 lacrimal apparatus disease 9.9 MUC5AC MUC4
25 microcystic adenoma 9.9 MUC6 MUC1
26 cystadenocarcinoma 9.8 MUC5AC MUC1
27 lung sarcomatoid carcinoma 9.8 MUC4 MUC1
28 mucinous adenocarcinoma 9.8 MUC5AC MUC1
29 mammary analogue secretory carcinoma 9.8 MUC4 MUC1
30 nonspecific interstitial pneumonia 9.8 MUC5B MUC1
31 adenomyoma 9.8 MUC4 MUC1
32 pancreatic signet ring cell adenocarcinoma 9.8 MUC5AC MUC1
33 sarcomatoid mesothelioma 9.8 MUC4 MUC1
34 tubular adenocarcinoma 9.8 MUC5AC MUC1
35 glandular cystitis 9.8 MUC5AC MUC1
36 pancreatic mucinous cystadenoma 9.8 MUC5AC MUC1
37 acute cholangitis 9.8 MUC5AC MUC1
38 colorectal cancer, hereditary nonpolyposis, type 8 9.8 MUC5AC MUC1
39 dental caries 9.8 MUC7 MUC5B
40 complete androgen insensitivity syndrome 9.8 MUC5AC MUC1
41 androgen insensitivity syndrome 9.8 MUC5AC MUC1
42 otitis media 9.7 MUC5B MUC5AC MUC4
43 meconium ileus 9.7 MUC5AC MUC1
44 bronchiolo-alveolar adenocarcinoma 9.7 MUC6 MUC5AC MUC4
45 ampulla of vater adenocarcinoma 9.7 MUC5AC MUC1
46 myxofibrosarcoma 9.7 MUC4 MUC1
47 mucinous tubular and spindle renal cell carcinoma 9.6 MUC6 MUC4 MUC1
48 adenosquamous carcinoma 9.6 MUC4 MUC1
49 colloid carcinoma of the pancreas 9.6 MUC5B MUC5AC MUC1
50 intrahepatic biliary papillomatosis 9.6 MUC5B MUC5AC MUC1

Comorbidity relations with Chronic Ethmoiditis via Phenotypic Disease Network (PDN):


Acute Ethmoiditis Acute Maxillary Sinusitis
Bronchitis Chronic Frontal Sinusitis
Chronic Maxillary Sinusitis Chronic Sphenoidal Sinusitis
Hypertension, Essential

Graphical network of the top 20 diseases related to Chronic Ethmoiditis:



Diseases related to Chronic Ethmoiditis

Symptoms & Phenotypes for Chronic Ethmoiditis

Drugs & Therapeutics for Chronic Ethmoiditis

Search Clinical Trials , NIH Clinical Center for Chronic Ethmoiditis

Genetic Tests for Chronic Ethmoiditis

Anatomical Context for Chronic Ethmoiditis

Publications for Chronic Ethmoiditis

Articles related to Chronic Ethmoiditis:

(show all 23)
# Title Authors PMID Year
1
[One case of oculomotor nerve paralysis caused by chronic ethmoidal sinusitis]. 61
30453409 2018
2
[Mucopyocele of the ethmoidal labyrinth]. 61
21983676 2011
3
Ethmoid silent sinus syndrome causing inward displacement of the orbit: case report. 61
19607744 2010
4
Bacteriology of chronic sinusitis: the bulla ethmoidalis content. 61
12012949 2002
5
Expression of mucin genes in chronic ethmoiditis. 61
10887622 2000
6
Peripheral scotoma associated with chronic ethmoidal sinusitis. A case report and review of the literature. 61
9695165 1998
7
Allergy and sinusitis. 61
9444371 1997
8
Temporary nasosinusal drainage and lavage in chronic maxillary sinusitis. Statistical study on 847 maxillary sinuses. 61
8239346 1993
9
Chronic ethmoidal sinusitis. 61
8483379 1993
10
Tryptase in nasal fluid is a useful marker of allergic rhinitis. 61
8457035 1993
11
Relationship of chronic ethmoidal sinusitis, maxillary sinusitis, and ostial permeability controlled by sinusomanometry: statistical study. 61
1405991 1992
12
[Indications and results apropos of 290 endonasal ethmoidectomies]. 61
1344534 1992
13
Microbiology and histopathology of chronic ethmoiditis. 61
1774807 1991
14
[Sarcoidosis of the ethmoid sinus. Apropos of a case]. 61
2018278 1991
15
Microsurgical treatment of recurrent nasal polyposis. 61
2772491 1989
16
[Treatment of chronic ethmoiditis patients]. 61
6710753 1984
17
Rhinitis medicamentosa. 61
6169966 1981
18
[Treatment of chronic ethmoiditis by the administration of drugs into the cells of ethmoid labyrinth]. 61
716109 1978
19
Radiological treatment of chronic ethmoiditis. 61
13936247 1962
20
Management of chronic ethmoiditis and sphenoiditis. 61
13113754 1954
21
Chronic ethmoiditis; development, symptoms, diagnosis, and treatment. 61
18905161 1948
22
THE CONSERVATIVE AND SURGICAL TREATMENT OF CHRONIC ETHMOIDITIS. 61
20774166 1928
23
CHRONIC ETHMOIDITIS. 61
20774165 1928

Variations for Chronic Ethmoiditis

Expression for Chronic Ethmoiditis

Search GEO for disease gene expression data for Chronic Ethmoiditis.

Pathways for Chronic Ethmoiditis

Pathways related to Chronic Ethmoiditis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.47 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1
2
Show member pathways
13.27 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1
3
Show member pathways
13.17 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1
4
Show member pathways
12.15 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1
5
Show member pathways
11.9 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1
6
Show member pathways
11.6 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1
7
Show member pathways
11.14 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1

GO Terms for Chronic Ethmoiditis

Cellular components related to Chronic Ethmoiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.87 PCSK9 MUC7 MUC6 MUC5B MUC5AC MUC4
2 extracellular exosome GO:0070062 9.77 MUC7 MUC5B MUC5AC MUC4 MUC1
3 extracellular space GO:0005615 9.73 PCSK9 MUC6 MUC5B MUC5AC MUC4 MUC1
4 extracellular region GO:0005576 9.5 PCSK9 MUC7 MUC6 MUC5B MUC5AC MUC4
5 extracellular matrix GO:0031012 9.46 MUC6 MUC5B MUC5AC MUC4
6 Golgi lumen GO:0005796 9.1 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1

Biological processes related to Chronic Ethmoiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.43 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1
2 regulation of signaling receptor activity GO:0010469 9.26 PCSK9 MUC4
3 maintenance of gastrointestinal epithelium GO:0030277 9.16 MUC6 MUC4
4 O-glycan processing GO:0016266 9.1 MUC7 MUC6 MUC5B MUC5AC MUC4 MUC1

Sources for Chronic Ethmoiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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