MCID: CHR053
MIFTS: 27

Chronic Follicular Conjunctivitis

Categories: Eye diseases

Aliases & Classifications for Chronic Follicular Conjunctivitis

MalaCards integrated aliases for Chronic Follicular Conjunctivitis:

Name: Chronic Follicular Conjunctivitis 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:13326
ICD9CM 36 372.12
SNOMED-CT 69 39429002
ICD10 34 H10.43
UMLS 74 C0155147

Summaries for Chronic Follicular Conjunctivitis

MalaCards based summary : Chronic Follicular Conjunctivitis is related to chlamydia and conjunctivitis. An important gene associated with Chronic Follicular Conjunctivitis is IL1A (Interleukin 1 Alpha), and among its related pathways/superpathways are Tuberculosis and IL-1 Family Signaling Pathways. Affiliated tissues include eye, and related phenotypes are Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression and neoplasm

Related Diseases for Chronic Follicular Conjunctivitis

Diseases related to Chronic Follicular Conjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Related Disease Score Top Affiliating Genes
1 chlamydia 30.1 IL1A IL1B
2 conjunctivitis 10.4
3 irritant dermatitis 10.0 IL1A IL1B
4 stachybotrys chartarum 10.0 IL1A IL1B
5 limbal stem cell deficiency 10.0 IL1A IL1B
6 meningococcemia 10.0 IL1A IL1B
7 gingival disease 10.0 IL1A IL1B
8 pulpitis 10.0 IL1A IL1B
9 root resorption 10.0 IL1A IL1B
10 keratoconjunctivitis sicca 10.0 IL1A IL1B
11 idiopathic neutropenia 10.0 IL1A IL1B
12 bacterial vaginosis 10.0 IL1A IL1B
13 somatoform disorder 10.0 IL1A IL1B
14 silicosis 10.0 IL1A IL1B
15 tonsillitis 10.0 IL1A IL1B
16 aggressive periodontitis 10.0 IL1A IL1B
17 contact dermatitis 10.0 IL1A IL1B
18 osteomyelitis 10.0 IL1A IL1B
19 bone inflammation disease 10.0 IL1A IL1B
20 graft-versus-host disease 9.9 IL1A IL1B
21 epithelial basement membrane dystrophy 9.9 IL1A MMP9
22 pertussis 9.9 IL1A IL1B
23 follicular lymphoma 9.9
24 lymphoma 9.9
25 rhinosporidiosis 9.9
26 leishmaniasis 9.9 IL1A IL1B
27 pulmonary fibrosis 9.9 IL1B MMP9
28 corneal ulcer 9.9 IL1B MMP9
29 cholesteatoma of middle ear 9.9 IL1A MMP9
30 central nervous system tuberculosis 9.9 IL1B MMP9
31 preterm premature rupture of the membranes 9.8 IL1B MMP9
32 appendicitis 9.8 IL1B MMP9
33 keratitis, hereditary 9.8 IL1B MMP9
34 lyme disease 9.8 IL1B MMP9
35 fatty liver disease 9.8 IL1A IL1B
36 bacterial meningitis 9.8 IL1B MMP9
37 meningitis 9.8 IL1B MMP9
38 brain edema 9.8 IL1B MMP9
39 psoriatic arthritis 9.8 IL1A IL1B
40 stomach disease 9.8 IL1B MMP9
41 arteries, anomalies of 9.8 IL1B MMP9
42 respiratory system disease 9.7 IL1B MMP9
43 demyelinating disease 9.7 IL1B MMP9
44 gastrointestinal system disease 9.7 IL1B MMP9
45 intervertebral disc disease 9.6 IL1A IL1B MMP9
46 chorioamnionitis 9.6 IL1A IL1B MMP9
47 gingivitis 9.6 IL1A IL1B MMP9
48 proteasome-associated autoinflammatory syndrome 1 9.6 IL1A IL1B MMP9
49 periodontitis 9.6 IL1A IL1B MMP9
50 interstitial lung disease 9.6 IL1A IL1B MMP9

Graphical network of the top 20 diseases related to Chronic Follicular Conjunctivitis:



Diseases related to Chronic Follicular Conjunctivitis

Symptoms & Phenotypes for Chronic Follicular Conjunctivitis

GenomeRNAi Phenotypes related to Chronic Follicular Conjunctivitis according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression GR00224-A-2 8.62 IL1A MMP9

MGI Mouse Phenotypes related to Chronic Follicular Conjunctivitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.8 IL1A IL1B MMP9

Drugs & Therapeutics for Chronic Follicular Conjunctivitis

Search Clinical Trials , NIH Clinical Center for Chronic Follicular Conjunctivitis

Genetic Tests for Chronic Follicular Conjunctivitis

Anatomical Context for Chronic Follicular Conjunctivitis

MalaCards organs/tissues related to Chronic Follicular Conjunctivitis:

42
Eye

Publications for Chronic Follicular Conjunctivitis

Articles related to Chronic Follicular Conjunctivitis:

# Title Authors Year
1
Chronic Follicular Conjunctivitis in a Middle-aged Woman. ( 29801089 )
2018
2
Follicular Lymphoma Presenting Solely as Chronic Follicular Conjunctivitis. ( 26606298 )
2016
3
Topical Cyclosporine A 1% for the Treatment of Chronic Follicular Conjunctivitis. ( 25503906 )
2014
4
Ocular rhinosporidiosis presenting as chronic follicular conjunctivitis in a contact lens wearer. ( 19667358 )
2009
5
Prevalence of Chlamydia trachomatis pooled serotypes BDE and FGK in children with chronic follicular conjunctivitis. ( 11033122 )
2000
6
Chronic follicular conjunctivitis associated with Chlamydia psittaci or Chlamydia pneumoniae. ( 9636859 )
1998
7
Isolation of a Chlamydia-like agent in essential conjunctival atrophy and chronic follicular conjunctivitis. ( 4332001 )
1971
8
Chronic follicular conjunctivitis and its etiological agent. ( 5742668 )
1968
9
A new type of chronic follicular conjunctivitis with corneal changes. ( 6025164 )
1967

Variations for Chronic Follicular Conjunctivitis

Expression for Chronic Follicular Conjunctivitis

Search GEO for disease gene expression data for Chronic Follicular Conjunctivitis.

Pathways for Chronic Follicular Conjunctivitis

Pathways related to Chronic Follicular Conjunctivitis according to GeneCards Suite gene sharing:

(show all 29)
# Super pathways Score Top Affiliating Genes
1 11.9 IL1A IL1B
2
Show member pathways
11.88 IL1A IL1B
3
Show member pathways
11.87 IL1A IL1B
4 11.84 IL1A IL1B
5
Show member pathways
11.82 IL1A IL1B MMP9
6 11.73 IL1A IL1B
7
Show member pathways
11.72 IL1B MMP9
8
Show member pathways
11.7 IL1A IL1B
9 11.65 IL1B MMP9
10 11.64 IL1A IL1B MMP9
11 11.62 IL1A IL1B
12 11.59 IL1A IL1B
13 11.57 IL1A IL1B
14 11.53 IL1A IL1B
15 11.5 IL1A IL1B
16 11.44 IL1A IL1B
17 11.41 IL1A IL1B MMP9
18 11.4 IL1B MMP9
19 11.32 IL1B MMP9
20 11.2 IL1A IL1B
21 11.19 IL1A IL1B MMP9
22 11.18 IL1A IL1B
23 11.13 IL1A IL1B
24 11 IL1A IL1B
25 10.98 IL1A IL1B
26 10.87 IL1A IL1B
27 10.77 IL1B MMP9
28
Show member pathways
10.6 IL1A IL1B MMP9
29 10.1 IL1A IL1B

GO Terms for Chronic Follicular Conjunctivitis

Biological processes related to Chronic Follicular Conjunctivitis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of angiogenesis GO:0045766 9.51 IL1A IL1B
2 interleukin-1-mediated signaling pathway GO:0070498 9.49 IL1A IL1B
3 positive regulation of cell division GO:0051781 9.48 IL1A IL1B
4 embryo implantation GO:0007566 9.46 IL1B MMP9
5 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.43 IL1A IL1B
6 cytokine-mediated signaling pathway GO:0019221 9.43 IL1A IL1B MMP9
7 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.4 IL1A IL1B
8 positive regulation of mitotic nuclear division GO:0045840 9.37 IL1A IL1B
9 positive regulation of vascular endothelial growth factor production GO:0010575 9.32 IL1A IL1B
10 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.16 IL1A IL1B
11 ectopic germ cell programmed cell death GO:0035234 8.96 IL1A IL1B
12 fever generation GO:0001660 8.62 IL1A IL1B

Molecular functions related to Chronic Follicular Conjunctivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 8.62 IL1A IL1B

Sources for Chronic Follicular Conjunctivitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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