MCID: CHR053
MIFTS: 28

Chronic Follicular Conjunctivitis

Categories: Eye diseases

Aliases & Classifications for Chronic Follicular Conjunctivitis

MalaCards integrated aliases for Chronic Follicular Conjunctivitis:

Name: Chronic Follicular Conjunctivitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13326
ICD10 33 H10.43
ICD9CM 35 372.12
SNOMED-CT 68 39429002
UMLS 73 C0155147

Summaries for Chronic Follicular Conjunctivitis

MalaCards based summary : Chronic Follicular Conjunctivitis is related to chlamydia and congenital hypogammaglobulinemia. An important gene associated with Chronic Follicular Conjunctivitis is IL1A (Interleukin 1 Alpha), and among its related pathways/superpathways are IL-2 Pathway and Fluid shear stress and atherosclerosis. Affiliated tissues include eye, and related phenotypes are Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression and neoplasm

Related Diseases for Chronic Follicular Conjunctivitis

Diseases related to Chronic Follicular Conjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 chlamydia 30.0 CD79A IL1B
2 congenital hypogammaglobulinemia 10.3 CD79A IL1A
3 chronic graft versus host disease 10.3 CD79A IL1A
4 cryptosporidiosis 10.3 CD79A IL1A
5 dysentery 10.3 CD79A IL1A
6 lung lymphoma 10.3 CD79A IL1A
7 conjunctivitis 10.3
8 irritant dermatitis 10.2 IL1A IL1B
9 stachybotrys chartarum 10.2 IL1A IL1B
10 limbal stem cell deficiency 10.2 IL1A IL1B
11 meningococcemia 10.2 IL1A IL1B
12 aseptic meningitis 10.2 IL1A IL1B
13 pulpitis 10.2 IL1A IL1B
14 root resorption 10.2 IL1A IL1B
15 idiopathic neutropenia 10.2 IL1A IL1B
16 bacterial vaginosis 10.2 IL1A IL1B
17 somatoform disorder 10.2 IL1A IL1B
18 osteosclerotic myeloma 10.1 CD79A IL1B
19 aggressive periodontitis 10.1 IL1A IL1B
20 jejunoileitis 10.1 CD79A IL1B
21 primary amebic meningoencephalitis 10.1 CD79A IL1B
22 silicosis 10.1 IL1A IL1B
23 pneumoconiosis 10.1 IL1A IL1B
24 gingival disease 10.1 CD79A IL1B
25 middle ear disease 10.1 CD79A IL1B
26 commensal bacterial infectious disease 10.1 CD79A IL1B
27 q fever 10.1 CD79A IL1B
28 autoinflammation, lipodystrophy, and dermatosis syndrome 10.1 IL1A IL1B
29 contact dermatitis 10.1 IL1A IL1B
30 osteomyelitis 10.1 IL1A IL1B
31 stomach disease 10.1 CD79A IL1B
32 extrinsic allergic alveolitis 10.1 CD79A IL1B
33 primary bacterial infectious disease 10.0 CD79A IL1B
34 graft-versus-host disease 10.0 IL1A IL1B
35 toxoplasmosis 10.0 CD79A IL1B
36 intestinal disease 10.0 CD79A IL1B
37 hypersensitivity reaction disease 10.0 CD79A IL1B
38 otitis media 9.9 CD79A IL1B
39 blepharochalasis 9.9 CD79A MMP9
40 parotitis 9.9 CD79A MMP9
41 lymphocytic colitis 9.9 CD79A MMP9
42 acquired immunodeficiency syndrome 9.9 CD79A IL1B
43 periodontosis 9.9 CD79A MMP9
44 pertussis 9.9 IL1A IL1B
45 immune system disease 9.9 CD79A IL1B
46 cholesteatoma of middle ear 9.8 IL1A MMP9
47 leishmaniasis 9.8 IL1A IL1B
48 pharynx cancer 9.8 CD79A MMP9
49 aging 9.8
50 follicular lymphoma 9.8

Graphical network of the top 20 diseases related to Chronic Follicular Conjunctivitis:



Diseases related to Chronic Follicular Conjunctivitis

Symptoms & Phenotypes for Chronic Follicular Conjunctivitis

GenomeRNAi Phenotypes related to Chronic Follicular Conjunctivitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression GR00224-A-2 8.62 IL1A MMP9

MGI Mouse Phenotypes related to Chronic Follicular Conjunctivitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 CD79A IL1A IL1B MMP9

Drugs & Therapeutics for Chronic Follicular Conjunctivitis

Search Clinical Trials , NIH Clinical Center for Chronic Follicular Conjunctivitis

Genetic Tests for Chronic Follicular Conjunctivitis

Anatomical Context for Chronic Follicular Conjunctivitis

MalaCards organs/tissues related to Chronic Follicular Conjunctivitis:

41
Eye

Publications for Chronic Follicular Conjunctivitis

Articles related to Chronic Follicular Conjunctivitis:

# Title Authors Year
1
Chronic Follicular Conjunctivitis in a Middle-aged Woman. ( 29801089 )
2018
2
Follicular Lymphoma Presenting Solely as Chronic Follicular Conjunctivitis. ( 26606298 )
2016
3
Topical Cyclosporine A 1% for the Treatment of Chronic Follicular Conjunctivitis. ( 25503906 )
2014
4
Ocular rhinosporidiosis presenting as chronic follicular conjunctivitis in a contact lens wearer. ( 19667358 )
2009
5
Prevalence of Chlamydia trachomatis pooled serotypes BDE and FGK in children with chronic follicular conjunctivitis. ( 11033122 )
2000
6
Chronic follicular conjunctivitis associated with Chlamydia psittaci or Chlamydia pneumoniae. ( 9636859 )
1998
7
Isolation of a Chlamydia-like agent in essential conjunctival atrophy and chronic follicular conjunctivitis. ( 4332001 )
1971
8
Chronic follicular conjunctivitis and its etiological agent. ( 5742668 )
1968
9
A new type of chronic follicular conjunctivitis with corneal changes. ( 6025164 )
1967

Variations for Chronic Follicular Conjunctivitis

Expression for Chronic Follicular Conjunctivitis

Search GEO for disease gene expression data for Chronic Follicular Conjunctivitis.

Pathways for Chronic Follicular Conjunctivitis

GO Terms for Chronic Follicular Conjunctivitis

Biological processes related to Chronic Follicular Conjunctivitis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.61 IL1A IL1B MMP9
2 interleukin-1-mediated signaling pathway GO:0070498 9.54 IL1A IL1B
3 positive regulation of JNK cascade GO:0046330 9.52 IL1A IL1B
4 positive regulation of interleukin-6 production GO:0032755 9.51 IL1A IL1B
5 positive regulation of cell division GO:0051781 9.49 IL1A IL1B
6 embryo implantation GO:0007566 9.48 IL1B MMP9
7 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.46 IL1A IL1B
8 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.4 IL1A IL1B
9 positive regulation of vascular endothelial growth factor production GO:0010575 9.37 IL1A IL1B
10 positive regulation of mitotic nuclear division GO:0045840 9.32 IL1A IL1B
11 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.26 IL1A IL1B
12 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.16 IL1A IL1B
13 ectopic germ cell programmed cell death GO:0035234 8.96 IL1A IL1B
14 fever generation GO:0001660 8.62 IL1A IL1B

Molecular functions related to Chronic Follicular Conjunctivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 8.62 IL1A IL1B

Sources for Chronic Follicular Conjunctivitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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