MCID: CHR088
MIFTS: 18

Chronic Inflammation of Lacrimal Passage

Categories: Eye diseases

Aliases & Classifications for Chronic Inflammation of Lacrimal Passage

MalaCards integrated aliases for Chronic Inflammation of Lacrimal Passage:

Name: Chronic Inflammation of Lacrimal Passage 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:9935
ICD10 33 H04.4
ICD9CM 35 375.4
UMLS 73 C0155239

Summaries for Chronic Inflammation of Lacrimal Passage

MalaCards based summary : Chronic Inflammation of Lacrimal Passage is related to atrophic rhinitis and dacryocystocele. An important gene associated with Chronic Inflammation of Lacrimal Passage is DCXR (Dicarbonyl And L-Xylulose Reductase). Affiliated tissues include eye, and related phenotypes are mortality/aging and nervous system

Related Diseases for Chronic Inflammation of Lacrimal Passage

Diseases in the Acute Inflammation of Lacrimal Passage family:

Chronic Inflammation of Lacrimal Passage

Diseases related to Chronic Inflammation of Lacrimal Passage via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 atrophic rhinitis 10.1 DCXR EXT1
2 dacryocystocele 10.1 DCXR KCNJ11
3 lacrimal duct obstruction 10.1 DCXR PGRMC1
4 rectosigmoid junction neoplasm 10.1 DCXR KCNJ11
5 dental anomalies and short stature 9.9 ALG10B AVIL
6 diverticulitis 9.9 DCXR SDC1
7 dacryocystitis 9.9 ALG10B DCXR EXT1 IFT122 TRIP12
8 acute inflammation of lacrimal passage 9.9 ALG10B DCXR EXT1 IFT122 TRIP12
9 superior mesenteric artery syndrome 9.8 PGRMC1 WDFY2
10 acute dacryocystitis 9.7 ALG10 ALG10B AVIL DCXR TNN
11 chronic dacryocystitis 8.3 ALG10 ALG10B AVIL DCXR EXT1 GRN

Graphical network of the top 20 diseases related to Chronic Inflammation of Lacrimal Passage:



Diseases related to Chronic Inflammation of Lacrimal Passage

Symptoms & Phenotypes for Chronic Inflammation of Lacrimal Passage

MGI Mouse Phenotypes related to Chronic Inflammation of Lacrimal Passage:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.65 ALG10 AVIL EXT1 GRN IFT122 KCNJ11
2 nervous system MP:0003631 9.23 ALG10 AVIL EXT1 GRN IFT122 KCNJ11

Drugs & Therapeutics for Chronic Inflammation of Lacrimal Passage

Search Clinical Trials , NIH Clinical Center for Chronic Inflammation of Lacrimal Passage

Genetic Tests for Chronic Inflammation of Lacrimal Passage

Anatomical Context for Chronic Inflammation of Lacrimal Passage

MalaCards organs/tissues related to Chronic Inflammation of Lacrimal Passage:

41
Eye

Publications for Chronic Inflammation of Lacrimal Passage

Variations for Chronic Inflammation of Lacrimal Passage

Expression for Chronic Inflammation of Lacrimal Passage

Search GEO for disease gene expression data for Chronic Inflammation of Lacrimal Passage.

Pathways for Chronic Inflammation of Lacrimal Passage

GO Terms for Chronic Inflammation of Lacrimal Passage

Cellular components related to Chronic Inflammation of Lacrimal Passage according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.63 ALG10 ALG10B EXT1 GRN KCNJ11 PGRMC1
2 neuron projection GO:0043005 9.26 AVIL PGRMC1 SRCIN1 TNN
3 neuronal cell body GO:0043025 8.92 KCNJ11 PGRMC1 SRCIN1 TNN

Biological processes related to Chronic Inflammation of Lacrimal Passage according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glycosaminoglycan biosynthetic process GO:0006024 9.16 EXT1 SDC1
2 protein glycosylation GO:0006486 9.13 ALG10 ALG10B EXT1
3 dolichol-linked oligosaccharide biosynthetic process GO:0006488 8.62 ALG10 ALG10B

Molecular functions related to Chronic Inflammation of Lacrimal Passage according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transferase activity, transferring glycosyl groups GO:0016757 9.33 ALG10 ALG10B EXT1
2 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity GO:0004583 8.96 ALG10 ALG10B
3 dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity GO:0106073 8.62 ALG10 ALG10B

Sources for Chronic Inflammation of Lacrimal Passage

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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