MCID: CHR464
MIFTS: 19

Chronic Intestinal Failure

Categories: Gastrointestinal diseases, Rare diseases, Infectious diseases, Fetal diseases

Aliases & Classifications for Chronic Intestinal Failure

MalaCards integrated aliases for Chronic Intestinal Failure:

Name: Chronic Intestinal Failure 59
Cif 59

Characteristics:

Orphanet epidemiological data:

59
chronic intestinal failure
Inheritance: Not applicable; Age of onset: All ages;

Classifications:



External Ids:

Orphanet 59 ORPHA294422

Summaries for Chronic Intestinal Failure

MalaCards based summary : Chronic Intestinal Failure, also known as cif, is related to crohn's disease and short bowel syndrome. An important gene associated with Chronic Intestinal Failure is REN (Renin). The drugs Denosumab and Bone Density Conservation Agents have been mentioned in the context of this disorder. Affiliated tissues include bone and liver.

Related Diseases for Chronic Intestinal Failure

Diseases in the Intestinal Disease family:

Chronic Intestinal Failure

Diseases related to Chronic Intestinal Failure via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 crohn's disease 9.6
2 short bowel syndrome 9.6
3 ehlers-danlos syndrome 9.6

Symptoms & Phenotypes for Chronic Intestinal Failure

Drugs & Therapeutics for Chronic Intestinal Failure

Drugs for Chronic Intestinal Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Denosumab Approved Phase 4 615258-40-7
2 Bone Density Conservation Agents Phase 4
3 Omega 3 Fatty Acid Nutraceutical Phase 4
4 Taurolidine Approved, Investigational Not Applicable 19388-87-5
5
Taurine Approved, Nutraceutical Not Applicable 107-35-7 1123
6 insulin
7 Mitogens
8 Pharmaceutical Solutions Not Applicable
9 Anti-Infective Agents Not Applicable
10 Insulin, Globin Zinc
11 Anti-Infective Agents, Local Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Denosumab in Metabolic Bone Disease in Chronic Intestinal Failure Patients Completed NCT02853539 Phase 4 Denosumab
2 The HOME Study (HPN With OMEGA-3) Recruiting NCT03282955 Phase 4 Lipidem;Lipofundin MCT 20%
3 A Trial of Taurine Supplementation in Parenteral Nutrition 1 Unknown status NCT00135044 Not Applicable
4 Catheter Salvage in Intestinal Failure Patients Completed NCT03222232
5 Using IGF-1 for Nutritional Monitoring Completed NCT03277014
6 The Correlation Between Nutrients and Muscle Mass Completed NCT03400046 Nutritional Product Supplementation
7 Clinical Trial With Catheter Locking TauroSept® (Taurolidine 2%) or Saline Solution 0,9% Completed NCT01826526 Not Applicable
8 A Monocenter Prospective Study to Evaluate the Efficacy of Peripherally Inserted Central Catheter to Tunnelled Central Catheter With Cuff in Home Parenteral Nutrition for Long-term Used. Terminated NCT01840033 Not Applicable

Search NIH Clinical Center for Chronic Intestinal Failure

Genetic Tests for Chronic Intestinal Failure

Anatomical Context for Chronic Intestinal Failure

MalaCards organs/tissues related to Chronic Intestinal Failure:

41
Bone, Liver

Publications for Chronic Intestinal Failure

Articles related to Chronic Intestinal Failure:

(show all 39)
# Title Authors Year
1
Intravenous lipid emulsions and liver function in adult patients with chronic intestinal failure: Results from a randomized clinical trial. ( 29960156 )
2018
2
Nutritional Therapy in Adult Short Bowel Syndrome Patients with Chronic Intestinal Failure. ( 29413019 )
2018
3
Vascular Ehlers-Danlos Syndrome: An Unusual Cause of Chronic Intestinal Failure in a Child. ( 29927864 )
2018
4
Home Parenteral Nutrition in Adult Patients With Chronic Intestinal Failure: Catheter-Related Complications Over 4 Decades at the Main Danish Tertiary Referral Center. ( 29505150 )
2018
5
High Incidence of Proteinuria in Children with Chronic Intestinal Failure Under Long-Term Parenteral Nutrition. ( 29077646 )
2017
6
Pediatric Chronic Intestinal Failure in Italy: Report from the 2016 Survey on Behalf of Italian Society for Gastroenterology, Hepatology and Nutrition (SIGENP). ( 29113094 )
2017
7
Corrigendum to "ESPEN guidelines on chronic intestinal failure in adults" [Clin Nutr 35 (2) (2016) 247-307]. ( 28027797 )
2017
8
Clinical classification of adult patients with chronic intestinal failure due to benign disease: An international multicenter cross-sectional survey. ( 28483328 )
2017
9
Managing Successful Pregnancies in Patients with Chronic Intestinal Failure on Home Parenteral Nutrition: Experience from a UK National Intestinal Failure Unit. ( 29253052 )
2017
10
Revised ESPEN Clinical Classification of Chronic Intestinal Failure: From 16 to 8 Categories. ( 28972458 )
2017
11
Home Parenteral Nutrition in Adult Patients With Chronic Intestinal Failure: The Evolution Over 4 Decades in a Tertiary Referral Center. ( 27323776 )
2016
12
Pregnancy is possible on long-term home parenteral nutrition in patients with chronic intestinal failure: Results of a long term retrospective observational study. ( 27624996 )
2016
13
ESPEN guidelines on chronic intestinal failure in adults. ( 26944585 )
2016
14
Home Parenteral Nutrition in Adult Patients With Chronic Intestinal Failure: Catheter-Related Complications Over 4 Decades at the Main Danish Tertiary Referral Center. ( 27875289 )
2016
15
A Single-Center, Adult Chronic Intestinal Failure Cohort Analyzed According to the ESPEN-Endorsed Recommendations, Definitions, and Classifications. ( 26488457 )
2015
16
"Ninjinto" (Ginseng Decoction), a Traditional Japanese Herbal Medicine, Improves Gastrointestinal Symptoms and Immune Competence in Patients with Chronic Intestinal Failure. ( 26495014 )
2015
17
Conception, Pregnancy, and Lactation Despite Chronic Intestinal Failure Requiring Home Parenteral Nutrition. ( 25788322 )
2015
18
Chronic intestinal failure after crohn disease: when to perform transplantation. ( 25162284 )
2014
19
Intestinal and multivisceral transplantation in patients with chronic intestinal failure. ( 22456144 )
2012
20
Catheter-related complications in long-term home parenteral nutrition patients with chronic intestinal failure. ( 23258588 )
2012
21
Chronic intestinal failure in children. ( 22778793 )
2012
22
Crohn's disease patients with chronic intestinal failure receiving long-term parenteral nutrition: a cross-national adult study. ( 21848855 )
2011
23
Long-term home parenteral nutrition in children with chronic intestinal failure: A 15-year experience at a single Italian centre. ( 20570223 )
2011
24
The complex relationship between magnesium and serum parathyroid hormone: a study in patients with chronic intestinal failure. ( 19441273 )
2009
25
Morbidity and mortality associated with chronic intestinal failure. ( 18497674 )
2008
26
Collaborative strategies to reduce mortality and morbidity in patients with chronic intestinal failure including those who are referred for small bowel transplantation. ( 18497673 )
2008
27
Chronic dehydration may impair renal function in patients with chronic intestinal failure on long-term parenteral nutrition. ( 16356596 )
2006
28
Guidelines for management of home parenteral support in adult chronic intestinal failure patients. ( 16473071 )
2006
29
Fluoride exposure and bone status in patients with chronic intestinal failure who are receiving home parenteral nutrition. ( 16762955 )
2006
30
A review of the instruments used to assess the quality of life of adult patients with chronic intestinal failure receiving parenteral nutrition at home. ( 16277762 )
2005
31
Safe and efficacious prolonged use of an olive oil-based lipid emulsion (ClinOleic) in chronic intestinal failure. ( 15297108 )
2004
32
Italian guidelines for intestinal transplantation: potential candidates among the adult patients managed by a medical referral center for chronic intestinal failure. ( 15110624 )
2004
33
Safety and efficacy of home parenteral nutrition for chronic intestinal failure: a 16-year experience at a single centre. ( 12846403 )
2003
34
Pregnancy in a patient with chronic intestinal failure on long-term parenteral nutrition. ( 12430564 )
2002
35
Specific changes in n -6 fatty acid metabolism in patients with chronic intestinal failure. ( 11884015 )
2002
36
Prognosis of patients with non-malignant chronic intestinal failure receiving long-term home parenteral nutrition. Gastroenterology 1995; 108:1005-10. ( 16843951 )
1995
37
Prognosis of patients with nonmalignant chronic intestinal failure receiving long-term home parenteral nutrition. ( 7698566 )
1995
38
Home parenteral nutrition for the management of chronic intestinal failure: a 34 patient-year experience. ( 8286774 )
1993
39
Home parenteral nutrition in chronic intestinal failure. ( 1739322 )
1992

Variations for Chronic Intestinal Failure

Expression for Chronic Intestinal Failure

Search GEO for disease gene expression data for Chronic Intestinal Failure.

Pathways for Chronic Intestinal Failure

GO Terms for Chronic Intestinal Failure

Sources for Chronic Intestinal Failure

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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