MCID: CHR067
MIFTS: 37

Chronic Intestinal Vascular Insufficiency

Categories: Cardiovascular diseases, Gastrointestinal diseases

Aliases & Classifications for Chronic Intestinal Vascular Insufficiency

MalaCards integrated aliases for Chronic Intestinal Vascular Insufficiency:

Name: Chronic Intestinal Vascular Insufficiency 12 15
Chronic Mesenteric Ischemia 12 72
Cmi - Chronic Mesenteric Ischaemia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8633
ICD9CM 35 557.1
UMLS 72 C0311262

Summaries for Chronic Intestinal Vascular Insufficiency

MalaCards based summary : Chronic Intestinal Vascular Insufficiency, also known as chronic mesenteric ischemia, is related to ischemia and fungal esophagitis, and has symptoms including abdominal angina An important gene associated with Chronic Intestinal Vascular Insufficiency is SPAG7 (Sperm Associated Antigen 7), and among its related pathways/superpathways are Fatty Acid Biosynthesis (WikiPathways) and Fatty acid biosynthesis (KEGG). Affiliated tissues include testes, colon and kidney, and related phenotype is digestive/alimentary.

Related Diseases for Chronic Intestinal Vascular Insufficiency

Diseases related to Chronic Intestinal Vascular Insufficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
# Related Disease Score Top Affiliating Genes
1 ischemia 11.0
2 fungal esophagitis 10.6 ATP4A ATP12A
3 gastroduodenal crohn's disease 10.6 ATP4A ATP12A
4 diclofenac allergy 10.6 ATP4A ATP12A
5 neonatal candidiasis 10.6 ATP4A ATP12A
6 squamous papillomatosis 10.6 ATP4A ATP12A
7 photoallergic dermatitis 10.6 ATP4A ATP12A
8 gastrointestinal neuroendocrine benign tumor 10.6 ATP4A ATP12A
9 aspiration pneumonitis 10.6 ATP4A ATP12A
10 toxic megacolon 10.6 ATP4A ATP12A
11 granulomatous gastritis 10.6 ATP4A ATP12A
12 gastric antral vascular ectasia 10.6 ATP4A ATP12A
13 acute laryngitis 10.6 ATP4A ATP12A
14 laryngitis 10.6 ATP4A ATP12A
15 gastric neuroendocrine neoplasm 10.6 ATP4A ATP12A
16 esophageal candidiasis 10.6 ATP4A ATP12A
17 duodenitis 10.6 ATP4A ATP12A
18 active peptic ulcer disease 10.5 ATP4A ATP12A
19 rumination disorder 10.5 ATP4A ATP12A
20 dyskinesia of esophagus 10.5 ATP4A ATP12A
21 peptic esophagitis 10.5 ATP4A ATP12A
22 capillary disease 10.5 ATP4A ATP12A
23 bile reflux 10.5 ATP4A ATP12A
24 ischemic neuropathy 10.5 ATP4A ATP12A
25 bladder calculus 10.5 ATP4A ATP12A
26 congenital disorder of deglycosylation 10.5 ATP4A ATP12A
27 anismus 10.5 ATP4A ATP12A
28 hernia, hiatus 10.5 ATP4A ATP12A
29 postsurgical hypothyroidism 10.5 ATP4A ATP12A
30 esophageal atresia/tracheoesophageal fistula 10.5 ATP4A ATP12A
31 lymphocytic colitis 10.5 ATP4A ATP12A
32 clostridium difficile colitis 10.5 ATP4A ATP12A
33 esophagitis, eosinophilic, 1 10.5 ATP4A ATP12A
34 diarrhea 1, secretory chloride, congenital 10.5 ATP4A ATP12A
35 laryngeal tuberculosis 10.5 ATP4A ATP12A
36 microscopic colitis 10.5 ATP4A ATP12A
37 esophagus adenocarcinoma 10.5 ATP4A ATP12A
38 eosinophilic gastritis 10.5 ATP4A ATP12A
39 chronic laryngitis 10.5 ATP4A ATP12A
40 superior mesenteric artery syndrome 10.5 ATP4A ATP12A
41 esophageal varix 10.4 ATP4A ATP12A
42 pancreatic steatorrhea 10.4 ATP4A ATP12A
43 jejunoileitis 10.4 ATP4A ATP12A
44 polyposis, skin pigmentation, alopecia, and fingernail changes 10.4 ATP4A ATP12A
45 lower urinary tract calculus 10.4 ATP4A ATP12A
46 gastric lymphoma 10.4 ATP4A ATP12A
47 aspiration pneumonia 10.4 ATP4A ATP12A
48 functional gastric disease 10.4 SPAG7 ATP4A ATP12A
49 myopathy, x-linked, with excessive autophagy 10.4 ATP4A ATP12A
50 lateral medullary syndrome 10.4 ATP4A ATP12A

Comorbidity relations with Chronic Intestinal Vascular Insufficiency via Phenotypic Disease Network (PDN): (show all 18)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Vascular Insufficiency of Intestine
Aortic Valve Disease 1 Deficiency Anemia
Esophagitis Familial Atrial Fibrillation
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Intermediate Coronary Syndrome
Intestinal Obstruction Iron Deficiency Anemia
Mitral Valve Disease Paralytic Ileus
Peripheral Vascular Disease Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Chronic Intestinal Vascular Insufficiency:



Diseases related to Chronic Intestinal Vascular Insufficiency

Symptoms & Phenotypes for Chronic Intestinal Vascular Insufficiency

UMLS symptoms related to Chronic Intestinal Vascular Insufficiency:


abdominal angina

MGI Mouse Phenotypes related to Chronic Intestinal Vascular Insufficiency:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.23 ATP12A ATP4A DYNLL1 MEIS2 POLB TNIP1

Drugs & Therapeutics for Chronic Intestinal Vascular Insufficiency

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Investigation of Chronic Intestinal Ischemia Recruiting NCT02914912
2 Evaluation of Covered Stents Versus Bare Metal Stents for Endovascular Treatment of Chronic Atherosclerotic Mesenteric Arterial Disease:a Randomised Study. Recruiting NCT03586739

Search NIH Clinical Center for Chronic Intestinal Vascular Insufficiency

Genetic Tests for Chronic Intestinal Vascular Insufficiency

Anatomical Context for Chronic Intestinal Vascular Insufficiency

MalaCards organs/tissues related to Chronic Intestinal Vascular Insufficiency:

41
Testes, Colon, Kidney, Small Intestine, Lymph Node

Publications for Chronic Intestinal Vascular Insufficiency

Articles related to Chronic Intestinal Vascular Insufficiency:

(show top 50) (show all 399)
# Title Authors PMID Year
1
Renal Autotransplant and Celiac Artery Bypass for Aneurysmal Degeneration Related to Neurofibromatosis Type 1. 38
31043138 2019
2
Abdominal Pain in the Elderly: An Unusual Case of Chronic Mesenteric Ischemia in the Emergency Department. 38
31403102 2019
3
The radiologist's guide to duplex ultrasound assessment of chronic mesenteric ischemia. 38
31410506 2019
4
Laparoscopic Surgery in Chronic Mesenteric Ischemia: Release of the Superior Mesenteric Artery from the Median Arcuate Ligament Using the Transperitoneal Left Retrorenal Approach. 38
31009713 2019
5
Covered stents versus Bare-metal stents in chronic atherosclerotic Gastrointestinal Ischemia (CoBaGI): study protocol for a randomized controlled trial. 38
31429792 2019
6
"Aortoiliac-Mesenteric Steal Syndrome" Treated with Inferior Mesenteric to Common Iliac Artery Transposition. 38
30802588 2019
7
Improving midterm results justify the continued use of bare-metal stents for endovascular therapy for chronic mesenteric ischemia. 38
31327617 2019
8
Prevalence and Impact of Malnutrition in Patients Surgically Treated for Chronic Mesenteric Ischemia. 38
31009732 2019
9
A Rare Case of Ischemia-Reperfusion Injury After Mesenteric Revascularization. 38
30982410 2019
10
Thirty-day readmission after endovascular or surgical revascularization for chronic mesenteric ischemia: Insights from the Nationwide Readmissions Database. 38
30739588 2019
11
Acute and Chronic Ischemic Disorders of the Small Bowel. 38
31065817 2019
12
Clinical management of chronic mesenteric ischemia. 38
31080602 2019
13
Intravascular Ultrasound-Assisted Endovascular Treatment of Mesenteric Malperfusion in a Multichannel Aortic Dissection With Full True Lumen Collapse. 38
30547707 2019
14
Detection of mesenteric ischemia by means of endoscopic visible light spectroscopy after luminal feeding. 38
30055157 2019
15
[Operative treatment of acute mesenteric ischaemia]. 38
30540513 2018
16
ACR Appropriateness Criteria® Imaging of Mesenteric Ischemia. 38
30392602 2018
17
Superior mesenteric artery stenting using embolic protection device for treatment of acute or chronic mesenteric ischemia. 38
29685508 2018
18
[Chronic Mesenteric Ischemia]. 38
30286488 2018
19
Spontaneous Isolated Inferior Mesenteric Artery Dissection With Chronic Mesenteric Ischemia: Case Report and Endovascular Management. 38
29716480 2018
20
Persistent symptom relief after revascularization in patients with single-artery chronic mesenteric ischemia. 38
29523436 2018
21
[Operative revascularization of visceral arteries in chronic mesenteric ischemia]. 38
29808329 2018
22
"Mesenteric Steal" Physiology as a Cause of Claudication and Chronic Mesenteric Ischemia. 38
29777839 2018
23
Exertional Abdominal Pain as a Rare Presenting Manifestation of Chronic Mesenteric Ischemia from a Single Mesenteric Vessel Stenosis. 38
29758324 2018
24
Multicenter study of retrograde open mesenteric artery stenting through laparotomy for treatment of acute and chronic mesenteric ischemia. 38
29548812 2018
25
Celiac Plexus Block as a Predictor of Surgical Outcome for Sympathetically Mediated Abdominal Pain in a Case of Suspected Median Arcuate Ligament Syndrome: A Case Report. 38
29634547 2018
26
Improved mortality in treatment of patients with endovascular interventions for chronic mesenteric ischemia. 38
29395425 2018
27
[Modern treatment of mesenteric ischemia]. 38
29776790 2018
28
Quality Improvement Guidelines for Mesenteric Angioplasty and Stent Placement for the Treatment of Chronic Mesenteric Ischemia. 38
29574024 2018
29
A systematic review and meta-analysis of endovascular versus open surgical revascularization for chronic mesenteric ischemia. 38
29571626 2018
30
Impact of Body Mass Index on Outcomes after Mesenteric Revascularization for Chronic Mesenteric Ischemia. 38
29217441 2018
31
A Nonsurgical Approach to Mesenteric Vascular Disease. 38
29419563 2018
32
Mesenteric Ischemia. 38
29413213 2018
33
Symptomatic Celiomesenteric Trunk: Variable Presentations and Outcomes in 2 Patients. 38
29556150 2018
34
Indications to open surgical revascularization of visceral arteries in the endovascular era. 38
30646738 2018
35
Bifurcated Stent Technique: A Viable Option for Treatment of Patients With Unusual Anatomy Presenting With Combined Chronic Mesenteric Ischemia and Diffuse Ischemic Gastric Ulcers. 38
29121843 2018
36
Use of REBOA to stabilize in-hospital iatrogenic intra-abdominal hemorrhage. 38
30306138 2018
37
Reversal of Acute Mesenteric Ischemia by Salvation of the Meandering Mesenteric Artery with Stenting of the Left Internal Iliac Artery. 38
28890058 2018
38
Patients with chronic mesenteric ischemia have an altered sublingual microcirculation. 38
30425547 2018
39
Effective kissing stent to severe stenosis of the superior mesenteric artery replacing the common hepatic artery. 38
30652149 2018
40
Endovascular Versus Surgical Revascularization for Chronic Mesenteric Ischemia: Insights From the National Inpatient Sample Database. 38
29217008 2017
41
Surgical and Endovascular Management of Patients with Chronic Mesenteric Ischemia: A Single Center Experience. 38
29336771 2017
42
Endovascular-First Approach for Chronic Mesenteric Ischemia: The Critical Need for Reporting Standards and High-Grade Evidence. 38
29217009 2017
43
Endovascular-First for Chronic Mesenteric Ischemia and the Importance of Long-Term Surveillance. 38
27856668 2017
44
Infrarenal aorta as the donor site for bypasses to the superior mesenteric artery for chronic mesenteric ischemia: A prospective clinical series of 24 patients. 38
28807407 2017
45
Endovascular Management for Symptomatic Chronic Mesenteric Ischemia: A Single-Center Experience. 38
28764609 2017
46
Retrograde Aortomesenteric Bypass with Left Retrorenal Route-"French Bypass" in 16 Cases of Chronic Mesenteric Ischemia. 38
28483622 2017
47
Chronic mesenteric ischemia and gastric ischemia: a bad combination. 38
28283323 2017
48
Endovascular recanalization of occluded superior mesenteric artery using retrograde access through the inferior mesenteric artery. 38
29349407 2017
49
Symptomatic Delayed Aortic Dissection After Superior Mesenteric Artery Stenting for Chronic Mesenteric Ischemia. 38
28376703 2017
50
Celiac and Superior/Inferior Mesenteric Angioplasty and Stenting for Chronic Mesenteric Ischemia: A Single-Center Experience. 38
27539454 2017

Variations for Chronic Intestinal Vascular Insufficiency

Expression for Chronic Intestinal Vascular Insufficiency

Search GEO for disease gene expression data for Chronic Intestinal Vascular Insufficiency.

Pathways for Chronic Intestinal Vascular Insufficiency

Pathways related to Chronic Intestinal Vascular Insufficiency according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.3 ACSL6 ACSL5
2 9.88 ACSL6 ACSL5

GO Terms for Chronic Intestinal Vascular Insufficiency

Biological processes related to Chronic Intestinal Vascular Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mesoderm formation GO:0001707 9.43 WLS GPI
2 ATP hydrolysis coupled proton transport GO:0015991 9.4 ATP4A ATP12A
3 long-chain fatty acid metabolic process GO:0001676 9.37 ACSL6 ACSL5
4 long-chain fatty-acyl-CoA biosynthetic process GO:0035338 9.32 ACSL6 ACSL5
5 cellular sodium ion homeostasis GO:0006883 9.26 ATP4A ATP12A
6 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP4A ATP12A
7 sodium ion export across plasma membrane GO:0036376 8.96 ATP4A ATP12A
8 cellular potassium ion homeostasis GO:0030007 8.62 ATP4A ATP12A

Molecular functions related to Chronic Intestinal Vascular Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 long-chain fatty acid-CoA ligase activity GO:0004467 9.26 ACSL6 ACSL5
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
3 decanoate-CoA ligase activity GO:0102391 8.96 ACSL6 ACSL5
4 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Chronic Intestinal Vascular Insufficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....