MCID: CHR067
MIFTS: 33

Chronic Intestinal Vascular Insufficiency

Categories: Cardiovascular diseases, Gastrointestinal diseases

Aliases & Classifications for Chronic Intestinal Vascular Insufficiency

MalaCards integrated aliases for Chronic Intestinal Vascular Insufficiency:

Name: Chronic Intestinal Vascular Insufficiency 12 15
Chronic Mesenteric Ischemia 12 71
Cmi - Chronic Mesenteric Ischaemia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8633
ICD9CM 34 557.1
SNOMED-CT 67 266448009
UMLS 71 C0311262

Summaries for Chronic Intestinal Vascular Insufficiency

MalaCards based summary : Chronic Intestinal Vascular Insufficiency, also known as chronic mesenteric ischemia, is related to median arcuate ligament syndrome and acalculous cholecystitis, and has symptoms including abdominal angina An important gene associated with Chronic Intestinal Vascular Insufficiency is ATP12A (ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit). Affiliated tissues include colon and kidney.

Related Diseases for Chronic Intestinal Vascular Insufficiency

Diseases related to Chronic Intestinal Vascular Insufficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 273)
# Related Disease Score Top Affiliating Genes
1 median arcuate ligament syndrome 30.5 CRP ATP4A ATP12A
2 acalculous cholecystitis 30.0 CRP ALB
3 gastric dilatation 30.0 CRP ATP4A ATP12A
4 constipation 29.7 CRP ATP4A ATP12A ALB
5 crohn's disease 29.4 S100A12 CRP ALB
6 ischemia 10.9
7 vagus nerve disease 10.3 ATP4A ATP12A
8 scalp dermatosis 10.3 ATP4A ATP12A
9 hemangioma of intra-abdominal structure 10.3 ATP4A ATP12A
10 acquired gastric outlet stenosis 10.3 ATP4A ATP12A
11 lingual goiter 10.3 ATP4A ATP12A
12 displacement of cardia through esophageal hiatus 10.3 ATP4A ATP12A
13 bacterial esophagitis 10.3 ATP4A ATP12A
14 cascade stomach 10.3 ATP4A ATP12A
15 benzylpenicillin allergy 10.3 ATP4A ATP12A
16 cervix erosion 10.3 ATP4A ATP12A
17 angiodysplasia of intestine 10.3 ATP4A ATP12A
18 angiodysplasia 10.3 ATP4A ATP12A
19 granulomatous gastritis 10.3 ATP4A ATP12A
20 laryngeal tuberculosis 10.3 ATP4A ATP12A
21 fungal esophagitis 10.3 ATP4A ATP12A
22 dieulafoy lesion 10.3 ATP4A ATP12A
23 esophagus melanoma 10.3 ATP4A ATP12A
24 cefuroxime allergy 10.3 ATP4A ATP12A
25 gastric gastrinoma 10.3 ATP4A ATP12A
26 pneumatosis cystoides intestinalis 10.3 ATP4A ATP12A
27 chronic laryngitis 10.3 ATP4A ATP12A
28 gastroduodenal crohn's disease 10.3 ATP4A ATP12A
29 central nervous system origin vertigo 10.3 ATP4A ATP12A
30 rumination disorder 10.3 ATP4A ATP12A
31 acute laryngitis 10.3 ATP4A ATP12A
32 gastroduodenitis 10.3 ATP4A ATP12A
33 barbiturate abuse 10.3 ATP4A ATP12A
34 duodenal gastrinoma 10.3 ATP4A ATP12A
35 gastric hemangioma 10.3 ATP4A ATP12A
36 polycystic echinococcosis 10.3 ATP4A ATP12A
37 lymphocytic gastritis 10.3 ATP4A ATP12A
38 x-linked chondrodysplasia punctata 1 10.3 ATP4A ATP12A
39 pancreatic gastrinoma 10.3 ATP4A ATP12A
40 gastric antral vascular ectasia 10.3 ATP4A ATP12A
41 outlet dysfunction constipation 10.3 ATP4A ATP12A
42 functional diarrhea 10.3 ATP4A ATP12A
43 squamous papillomatosis 10.3 ATP4A ATP12A
44 esophageal tuberculosis 10.3 ATP4A ATP12A
45 eosinophilic gastritis 10.3 ATP4A ATP12A
46 cough variant asthma 10.3 ATP4A ATP12A
47 biliary dyskinesia 10.3 ATP4A ATP12A
48 esophageal candidiasis 10.3 ATP4A ATP12A
49 postinflammatory pulmonary fibrosis 10.3 ATP4A ATP12A
50 diarrhea 1, secretory chloride, congenital 10.3 ATP4A ATP12A

Comorbidity relations with Chronic Intestinal Vascular Insufficiency via Phenotypic Disease Network (PDN): (show all 18)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Vascular Insufficiency of Intestine
Aortic Valve Disease 1 Deficiency Anemia
Esophagitis Familial Atrial Fibrillation
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Intermediate Coronary Syndrome
Intestinal Obstruction Iron Deficiency Anemia
Mitral Valve Disease Paralytic Ileus
Peripheral Vascular Disease Protein-Energy Malnutrition

Graphical network of the top 20 diseases related to Chronic Intestinal Vascular Insufficiency:



Diseases related to Chronic Intestinal Vascular Insufficiency

Symptoms & Phenotypes for Chronic Intestinal Vascular Insufficiency

UMLS symptoms related to Chronic Intestinal Vascular Insufficiency:


abdominal angina

Drugs & Therapeutics for Chronic Intestinal Vascular Insufficiency

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of Covered Stents Versus Bare Metal Stents for Endovascular Treatment of Chronic Atherosclerotic Mesenteric Arterial Disease:a Randomised Study. Recruiting NCT03586739
2 Investigation of Chronic Intestinal Ischemia Recruiting NCT02914912

Search NIH Clinical Center for Chronic Intestinal Vascular Insufficiency

Genetic Tests for Chronic Intestinal Vascular Insufficiency

Anatomical Context for Chronic Intestinal Vascular Insufficiency

MalaCards organs/tissues related to Chronic Intestinal Vascular Insufficiency:

40
Colon, Kidney

Publications for Chronic Intestinal Vascular Insufficiency

Articles related to Chronic Intestinal Vascular Insufficiency:

(show top 50) (show all 445)
# Title Authors PMID Year
1
Interdisciplinary approach in emergency revascularization and treatment for acute mesenteric ischemia. 61
33602217 2021
2
Non-invasive assessment of mesenteric hemodynamics in patients with suspected chronic mesenteric ischemia using 4D flow MRI. 61
33547918 2021
3
The Society for Vascular Surgery clinical practice guidelines define the optimal care of patients with chronic mesenteric ischemia. 61
33349350 2021
4
Chronic mesenteric ischemia: Clinical practice guidelines from the Society for Vascular Surgery. 61
33171195 2021
5
Evaluation of mesenteric artery disease in patients with severe aortic valve stenosis. 61
33452127 2021
6
Distal Superior Mesenteric Artery Endarterectomy Remains an Excellent Option for Mesenteric Revascularization in the Endovascular Era. 61
32634563 2021
7
Defining Duplex Ultrasound Criteria for In-Stent Restenosis of the Superior Mesenteric Artery. 61
33508454 2021
8
Revascularization of Isolated Superior Mesenteric Artery Dissection for Post-Mesenteric Infarction Exudative Enteropathy: The Contribution of a Multidisciplinary Care Teamwork. 61
33338574 2020
9
Mesenteric artery calcium scoring: a potential screening method for chronic mesenteric ischemia. 61
33263162 2020
10
Non-surgical treatment of chronic mesenteric ischemia owing to lesion in the SMA through the SMI: An option for consideration in frail patients. 61
32674881 2020
11
Percutaneous retrograde revascularization of chronic occlusions of the superior mesenteric artery via collaterals of the celiac artery. 61
33188614 2020
12
Chronic Mesenteric Ischemia: An Update. 61
32892243 2020
13
Reconstruction of superior mesenteric artery by prostheses placement in a case of chronic mesenteric ischemia: A case report and literature review. 61
32905147 2020
14
The radiologist's guide to duplex ultrasound assessment of chronic mesenteric ischemia. 61
31410506 2020
15
Long-Term Outcomes of Mesenteric Stenting and Analysis of In-Stent Restenosis Duplex Velocity Criteria. 61
32428638 2020
16
A Review on Aorta Mesenteric Bypass in Surgical Management of Mesenteric Ischemia: Indications, Techniques and Outcomes. 61
33312256 2020
17
Early and Midterm Outcomes of Open and Endovascular Revascularization of Chronic Mesenteric Ischemia. 61
32328781 2020
18
Abdominal Magnetic Resonance Angiography. 61
32624157 2020
19
The Incidence of Chronic Mesenteric Ischemia in the Well-Defined Region of a Dutch Mesenteric Ischemia Expert Center. 61
32955192 2020
20
Chronic Mesenteric Ischemia With Peristaltic Blanching. 61
32740080 2020
21
Recanalization of superior mesenteric artery chronic total occlusion using hybrid algorithm and dissection reentry device. 61
31925989 2020
22
Laser Atherectomy to Treat Severe In Stent Restenosis of the Superior Mesenteric Artery. 61
32373241 2020
23
Diagnostic and therapeutic approaches in chronic mesenteric ischemia have improved. 61
32364056 2020
24
Overweight Patients with Chronic Mesenteric Ischemia Undergo more Diagnostic Studies: A Retrospective Analysis. 61
32391770 2020
25
[Clinical implications of chronic mesenteric ischemia in elderly and senile patients]. 61
32598722 2020
26
Superior mesenteric artery endarterectomy for chronic mesenteric ischemia: A viable alternative in poor candidates for endovascular interventions. 61
31699006 2020
27
Renal and Mesenteric Artery Intervention. 61
32147118 2020
28
Dissecting visceral fibromuscular dysplasia reveals a new vascular phenotype of the disease: a report from the ARCADIA-POL study. 61
31913220 2020
29
Pearls, Pitfalls, and Conditions that Mimic Mesenteric Ischemia at CT. 61
32125953 2020
30
Endovascular Pressure Measurements to Assess the Functional Severity of Mesenteric Arterial Stenoses. 61
32007405 2020
31
Transient Reperfusion-Like Injury following Endovascular Treatment of Chronic Mesenteric Ischemia. 61
32007409 2020
32
How to manage chronic mesenteric ischemia? A deliberated strategy. 61
31580204 2020
33
A Short Series of Laparoscopic Mesenteric Bypasses for Chronic Mesenteric Ischemia. 61
32256075 2020
34
Improving midterm results justify the continued use of bare-metal stents for endovascular therapy for chronic mesenteric ischemia. 61
31327617 2020
35
Perioperative Microcirculatory Changes Detected with Gastroscopy Assisted Laser Doppler Flowmetry and Visible Light Spectroscopy in Patients with Median Arcuate Ligament Syndrome. 61
32982262 2020
36
Recanalization using direct stenting before bowel resection for acute-on-chronic superior mesenteric artery occlusion: A case report. 61
32126354 2020
37
Case report and systematic review of mesenteric artery by-pass for non-atherosclerotic mesenteric vascular disease. 61
32446211 2020
38
Symptom relief in patients undergoing endovascular management of chronic mesenteric ischemia. 61
31580041 2019
39
Total Endovascular Therapy of Abdominal Aortic Aneurysm, Peripheral Artery Disease, and Chronic Mesenteric Ischemia: A Challenging Case. 61
31915669 2019
40
The use of an upper extremity hemodialysis access site for stenting of the superior mesenteric artery for chronic mesenteric ischemia. 61
31660460 2019
41
Gastroscopy assisted laser Doppler flowmetry and visible light spectroscopy in patients with chronic mesenteric ischemia. 61
31560225 2019
42
Validation of a score chart to predict the risk of chronic mesenteric ischemia and development of an updated score chart. 61
31700639 2019
43
Gangrenous Gastritis: Unusual Cause Of Upper Gi Bleeding. 61
31933327 2019
44
[Endovascular treatment of chronic mesenteric ischemia]. 61
31474341 2019
45
Abdominal Pain in the Elderly: An Unusual Case of Chronic Mesenteric Ischemia in the Emergency Department. 61
31403102 2019
46
Weight Loss: A Significant Cue To The Diagnosis of Chronic Mesenteric Ischemia. 61
31598442 2019
47
Renal Autotransplant and Celiac Artery Bypass for Aneurysmal Degeneration Related to Neurofibromatosis Type 1. 61
31043138 2019
48
Covered stents versus Bare-metal stents in chronic atherosclerotic Gastrointestinal Ischemia (CoBaGI): study protocol for a randomized controlled trial. 61
31429792 2019
49
Laparoscopic Surgery in Chronic Mesenteric Ischemia: Release of the Superior Mesenteric Artery from the Median Arcuate Ligament Using the Transperitoneal Left Retrorenal Approach. 61
31009713 2019
50
Prevalence and Impact of Malnutrition in Patients Surgically Treated for Chronic Mesenteric Ischemia. 61
31009732 2019

Variations for Chronic Intestinal Vascular Insufficiency

Expression for Chronic Intestinal Vascular Insufficiency

Search GEO for disease gene expression data for Chronic Intestinal Vascular Insufficiency.

Pathways for Chronic Intestinal Vascular Insufficiency

GO Terms for Chronic Intestinal Vascular Insufficiency

Biological processes related to Chronic Intestinal Vascular Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular sodium ion homeostasis GO:0006883 9.26 ATP4A ATP12A
2 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
3 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
4 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP4A ATP12A

Molecular functions related to Chronic Intestinal Vascular Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Chronic Intestinal Vascular Insufficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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