CNKL
MCID: CHR680
MIFTS: 20

Chronic Lymphoproliferative Disorder of Natural Killer Cells (CNKL)

Categories: Blood diseases, Immune diseases, Rare diseases

Aliases & Classifications for Chronic Lymphoproliferative Disorder of Natural Killer Cells

MalaCards integrated aliases for Chronic Lymphoproliferative Disorder of Natural Killer Cells:

Name: Chronic Lymphoproliferative Disorder of Natural Killer Cells 60
Nk-Cell Lineage Granular Lymphocyte Proliferative Disorder 60
Chronic Lymphoproliferative Disorder of Nk-Cells 60
Chronic Nk-Cell Lymphocytosis 60
Chronic Nk Lymphocytosis 60
Clpd-Nk 60
Cnkl 60

Classifications:



External Ids:

Orphanet 60 ORPHA512017

Summaries for Chronic Lymphoproliferative Disorder of Natural Killer Cells

MalaCards based summary : Chronic Lymphoproliferative Disorder of Natural Killer Cells, also known as nk-cell lineage granular lymphocyte proliferative disorder, is related to chronic nk-cell lymphocytosis and lymphoproliferative syndrome. An important gene associated with Chronic Lymphoproliferative Disorder of Natural Killer Cells is STAT3 (Signal Transducer And Activator Of Transcription 3). Affiliated tissues include nk cells, bone and skin.

Related Diseases for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Diseases related to Chronic Lymphoproliferative Disorder of Natural Killer Cells via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 chronic nk-cell lymphocytosis 12.7
2 lymphoproliferative syndrome 10.3
3 chronic active epstein-barr virus infection 10.3
4 anemia, autoimmune hemolytic 10.1
5 autoimmune lymphoproliferative syndrome, type v 10.1
6 hemolytic anemia 10.1
7 leukemia 10.1
8 t-cell large granular lymphocyte leukemia 10.1
9 polyneuropathy 10.1
10 demyelinating polyneuropathy 10.1
11 large granular lymphocyte leukemia 10.1

Graphical network of the top 20 diseases related to Chronic Lymphoproliferative Disorder of Natural Killer Cells:



Diseases related to Chronic Lymphoproliferative Disorder of Natural Killer Cells

Symptoms & Phenotypes for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Drugs & Therapeutics for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Search Clinical Trials , NIH Clinical Center for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Genetic Tests for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Anatomical Context for Chronic Lymphoproliferative Disorder of Natural Killer Cells

MalaCards organs/tissues related to Chronic Lymphoproliferative Disorder of Natural Killer Cells:

42
Nk Cells, Bone, Skin, Kidney, Spinal Cord, T Cells

Publications for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Articles related to Chronic Lymphoproliferative Disorder of Natural Killer Cells:

(show top 50) (show all 98)
# Title Authors Year
1
Acroosteolysis in Systemic Sclerosis. ( 30454843 )
2019
2
Band acro-osteolysis in a middle-aged woman. ( 30914415 )
2019
3
STAT3 mutations in natural killer cells are associated with cytopenia in patients with chronic lymphoproliferative disorder of natural killer cells. ( 30859397 )
2019
4
Acroosteolysis in a patient with systemic lupus erythematosus/mixed connective tissue disease. ( 30184147 )
2018
5
Acroosteolysis in a patient with systemic lupus erythematosus/mixed connective tissue disease. ( 30312455 )
2018
6
Brachyonychia Associated with Acroosteolysis in Chronic Kidney Disease: How Phalange Shape Influences Nail Morphology. ( 30410893 )
2018
7
Whole genome sequencing and 6-year follow-up of a mother and daughter with frontometaphyseal dysplasia associated with keratitis, xerosis, poikiloderma, and acro-osteolysis: A case report. ( 29995760 )
2018
8
Occult dysraphism presenting with acro-osteolysis. ( 29633333 )
2018
9
Acro-osteolysis. ( 30308144 )
2018
10
Lamin A/C gene (LMNA) mutation associated with laminopathy: a rare cause of idiopathic acro-osteolysis. ( 30528549 )
2018
11
A Stab in the Back: An Unusual Case of Cutaneous Neural Infiltration as a Manifestation of Chronic Lymphoproliferative Disorder of Natural Killer Cells. ( 30371512 )
2018
12
Severe Acro-osteolysis in a Case of Limited Cutaneous Scleroderma. ( 28451545 )
2017
13
Acro-osteolysis. ( 27796661 )
2017
14
The 'Te' Technique for Restoring Fingertip Stability Post Traumatic Acro-Osteolysis - A Report and Review of Management Options. ( 29117838 )
2017
15
Digital clubbing: A patient with hypertrophic osteoarthropathy and the presence of acro-osteolysis. ( 29291924 )
2017
16
Acro-osteolysis as an indicator of severity in systemic sclerosis. ( 26746600 )
2016
17
IMAGES IN CLINICAL MEDICINE. Band Acro-osteolysis. ( 26244328 )
2015
18
Surfer's toe: trauma-induced idiopathic acro-osteolysis in the toes of a 46-year-old surfer: a case report. ( 22461275 )
2012
19
Acro-osteolysis. ( 22658741 )
2012
20
A patient with acro-osteolysis syndrome: Hajdu-Cheney. ( 20046011 )
2010
21
Chronic lymphoproliferative disorder of natural killer cells: a distinct entity with subtypes correlating with normal natural killer cell subsets. ( 20111066 )
2010
22
Acro-osteolysis of the big toe in a patient with psoriatic arthritis. ( 19738210 )
2009
23
Acro-osteolysis: a complication of Jadassohn-Lewandowsky syndrome. ( 17269978 )
2007
24
Catastrophic acro-osteolysis of hands in systemic sclerosis. ( 17551387 )
2007
25
Acro-osteolysis and symphalangism mutations. ( 15619682 )
2005
26
Hemifacial microsomia, external auditory canal atresia, deafness and Mullerian anomalies associated with acro-osteolysis: a new autosomal recessive syndrome? ( 12072792 )
2002
27
Acro-osteolysis in a patient with scleroderma. ( 11908276 )
2002
28
Isolated asymmetrical acro-osteolysis of the big toe in an elder patient with rheumatoid arthritisasymmetrical. ( 12102287 )
2002
29
Spinal dysraphism presenting as acro-osteolysis: report of four cases. ( 11358545 )
2001
30
Acro-osteolysis prior to diagnosis of leprosy. ( 11105499 )
2000
31
Osteoporosis associated with non-familial acro-osteolysis successful treatment with an anti-resorptive agent. ( 19078428 )
1999
32
Unusual and memorable. Acro-osteolysis of the terminal phalanges. ( 9797563 )
1998
33
Carpal tunnel syndrome presenting as sclerodactylia, nail dystrophy and acro-osteolysis in a 60-year-old woman. ( 9310726 )
1997
34
Congenital dysmorphism of finger and toenails associated with acro-osteolysis. ( 7999627 )
1994
35
Acro-osteolysis of phalanges in a case of cystic fibrosis. ( 1459688 )
1992
36
Idiopathic acro-osteolysis in an elderly woman. A 10-year follow-up. ( 1586583 )
1992
37
Persistent skin ulcers, mutilations, and acro-osteolysis in hereditary sensory and autonomic neuropathy with phospholipid excretion. Report of a family. ( 2808789 )
1989
38
Acro-osteolysis of the fingers in a spinal cord injury patient. A case report. ( 2913664 )
1989
39
Acroosteolysis and Raynaud's phenomenon after vinyl chloride exposure. ( 3176646 )
1988
40
Colchicine treatment in a case of pachydermoperiostosis with acroosteolysis. ( 3187331 )
1988
41
Pachydermoperiostosis and acro-osteolysis. ( 2976749 )
1988
42
Massive acroosteolysis in adult T-cell leukemia/lymphoma. ( 2887006 )
1987
43
Familial neurogenic acro-osteolysis, type Giaccai--report of two families. ( 3016383 )
1986
44
Acro-osteolysis. Etiologic and radiological considerations. ( 3485729 )
1986
45
Acro-osteolysis and the nail unit. ( 3790440 )
1986
46
Acroosteolysis: early marker of skeletal damage in patients with chronic renal insufficiency. ( 3843637 )
1985
47
Acro-osteolysis following snake and scorpion envenomation. ( 3842610 )
1985
48
Acro-osteolysis associated with hypertrophic pulmonary osteoarthropathy and pachydermoperiostosis. ( 3966121 )
1985
49
Idiopathic multicentric osteolysis with acro-osteolysis. A case report. ( 3968151 )
1985
50
Acro-osteolysis. ( 4045123 )
1985

Variations for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Expression for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Search GEO for disease gene expression data for Chronic Lymphoproliferative Disorder of Natural Killer Cells.

Pathways for Chronic Lymphoproliferative Disorder of Natural Killer Cells

GO Terms for Chronic Lymphoproliferative Disorder of Natural Killer Cells

Sources for Chronic Lymphoproliferative Disorder of Natural Killer Cells

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