MCID: CHR091
MIFTS: 33

Chronic Meningitis

Categories: Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Chronic Meningitis

MalaCards integrated aliases for Chronic Meningitis:

Name: Chronic Meningitis 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:10341
ICD9CM 36 322.2
SNOMED-CT 69 21664006
ICD10 34 G03.1
UMLS 74 C0154653

Summaries for Chronic Meningitis

MalaCards based summary : Chronic Meningitis is related to meningitis and lyme disease. An important gene associated with Chronic Meningitis is NLRP3 (NLR Family Pyrin Domain Containing 3), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Microglia Activation During Neuroinflammation: Microglia Polarization. Affiliated tissues include myeloid, brain and liver, and related phenotype is immune system.

Related Diseases for Chronic Meningitis

Diseases in the Meningitis family:

Viral Meningitis Chronic Meningitis
Bacterial Meningitis

Diseases related to Chronic Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 meningitis 30.9 CRP MMP9 NLRP3
2 lyme disease 29.5 CRP MMP9
3 granulomatous angiitis 29.4 CRP IL5
4 cinca syndrome 11.3
5 cryopyrin-associated periodic syndrome 10.3 CRP NLRP3
6 schnitzler syndrome 10.3 CRP NLRP3
7 muckle-wells syndrome 10.3 CRP NLRP3
8 exanthem 10.3 CRP NLRP3
9 pericardial effusion 10.2 CRP NLRP3
10 japanese spotted fever 10.2 CCL11 CRP
11 familial mediterranean fever 10.2 CRP NLRP3
12 diverticulitis 10.1 CRP MMP9
13 pelvic inflammatory disease 10.1 CRP MMP9
14 venous insufficiency 10.1 CRP MMP9
15 preterm premature rupture of the membranes 10.1 CRP MMP9
16 appendicitis 10.0 CRP MMP9
17 blepharitis 10.0 CCL11 MMP9
18 carotid stenosis 10.0 CRP MMP9
19 hydrocephalus 10.0
20 carotid artery disease 10.0 CRP MMP9
21 bone inflammation disease 10.0 CRP NLRP3
22 bacterial meningitis 10.0 CRP MMP9
23 multicentric castleman disease 10.0 CRP IL5
24 chorioamnionitis 10.0 CRP MMP9
25 paragonimiasis 10.0 IL5 MT-CO1
26 mesenteric lymphadenitis 10.0 CRP IL5
27 cercarial dermatitis 10.0 IL5 MT-CO1
28 norwegian scabies 10.0 IL5 MT-CO1
29 bladder disease 10.0 CRP MMP9
30 keratoconjunctivitis 10.0 CCL11 IL5
31 aortic disease 10.0 CRP MMP9 NLRP3
32 pemphigoid gestationis 9.9 CCL11 IL5
33 echinococcosis 9.9 IL5 MT-CO1
34 strongyloidiasis 9.9 CCL11 IL5
35 esophagitis 9.9 CCL11 IL5
36 esophagitis, eosinophilic, 1 9.9 CCL11 IL5
37 eosinophilic gastroenteritis 9.9 CCL11 IL5
38 chronic conjunctivitis 9.9 CCL11 IL5
39 eosinophilic gastritis 9.9 CCL11 IL5
40 chronic eosinophilic pneumonia 9.9 CCL11 IL5
41 eosinophilic pneumonia 9.9 CCL11 IL5
42 kimura disease 9.9 CCL11 IL5
43 parasitic helminthiasis infectious disease 9.9 IL5 MT-CO1
44 cysticercosis 9.9
45 folliculitis 9.9 CCL11 IL5
46 takayasu arteritis 9.9 CRP MMP9
47 radiculopathy 9.9 CCL11 IL5
48 pulmonary eosinophilia 9.9 CCL11 IL5
49 onchocerciasis 9.9 CCL11 IL5
50 allergic conjunctivitis 9.9 CCL11 IL5

Comorbidity relations with Chronic Meningitis via Phenotypic Disease Network (PDN):


Acute Cystitis Meningitis

Graphical network of the top 20 diseases related to Chronic Meningitis:



Diseases related to Chronic Meningitis

Symptoms & Phenotypes for Chronic Meningitis

MGI Mouse Phenotypes related to Chronic Meningitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.17 CCL11 CRP IL5 MMP9 MT-CO1 NLRP3

Drugs & Therapeutics for Chronic Meningitis

Search Clinical Trials , NIH Clinical Center for Chronic Meningitis

Genetic Tests for Chronic Meningitis

Anatomical Context for Chronic Meningitis

MalaCards organs/tissues related to Chronic Meningitis:

42
Myeloid, Brain, Liver, Eye, T Cells, Spinal Cord, Bone

Publications for Chronic Meningitis

Articles related to Chronic Meningitis:

(show top 50) (show all 119)
# Title Authors Year
1
Chronic meningitis with persistent hypoglycorrhachia: An unusual presentation of Lyme's disease. ( 31085878 )
2019
2
What's Next (Generation) for the Diagnosis of Chronic Meningitis? ( 29710076 )
2018
3
Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing. ( 29710329 )
2018
4
Chronic Meningitis and Hydrocephalus due to Sporothrix brasiliensis in Immunocompetent Adults: A Challenging Entity. ( 29977951 )
2018
5
Chronic Meningitis. ( 30273241 )
2018
6
Diagnostic Approach to Chronic Meningitis. ( 30366558 )
2018
7
Primary intracranial meningeal melanoma mimicking chronic meningitis: A case report. ( 30497968 )
2018
8
The Upside of Bias: A Case of Chronic Meningitis Due to Sporothrix Schenckii in an Immunocompetent Host. ( 28042367 )
2017
9
A Woman in Her 60s With Chronic Meningitis. ( 28114658 )
2017
10
Tracing the footprints: A case of chronic meningitis with unusual mononuclear cells in the cerebrospinal fluid. ( 28188694 )
2017
11
Primary central nervous system natural killer/T-cell lymphoma: An atypical case of chronic meningitis. ( 28222909 )
2017
12
Many faces of neurosarcoidosis: from chronic meningitis to myelopathy. ( 28598872 )
2017
13
Neurobrucellosis: an often forgotten cause of chronic meningitis. ( 26160851 )
2016
14
Chronic Meningitis: Simplifying a Diagnostic Challenge. ( 26888190 )
2016
15
Mycobacterium abscessus as a Cause of Chronic Meningitis: A Rare Clinical Entity. ( 27079354 )
2016
16
An unusual case of chronic meningitis due to histiocytic sarcoma of the central nervous system with meningeal dissemination. ( 27325388 )
2016
17
Chronic meningitis, hydrocephalus and spinal paraplegia in non-systemic histoplasmosis. ( 27338647 )
2016
18
Gliomatosis cerebri with spinal metastasis presenting with chronic meningitis in two boys. ( 26318497 )
2015
19
A 7-year-old girl with recurrent episodes of abdominal pain, seizures, and loss of vision: Primary diffuse leptomeningeal primitive neuroectodermal tumor masquerading as chronic meningitis. ( 26448234 )
2015
20
Chronic Meningitis Complicating Intracranial Hypertension in Neurobrucellosis: A Case Report. ( 24506671 )
2015
21
Evaluation and treatment of chronic meningitis. ( 25360204 )
2014
22
Chronic meningitis in systemic lupus erythematosus: An unusual etiology. ( 25506165 )
2014
23
Chronic meningitis with intracranial hypertension and bilateral neuroretinitis following Mycoplasma pneumoniae infection. ( 25538215 )
2014
24
Diffusion tensor imaging study of white matter damage in chronic meningitis. ( 24892826 )
2014
25
Chronic meningitis in immunocompromised adult Ethiopians visiting Tikur Anbessa Teaching Hospital and Ye'huleshet Clinic from 2003-2004. ( 24696988 )
2014
26
Hydrocephalus secondary to chronic meningitis. ( 24479823 )
2014
27
Primary leptomeningeal melanocytosis presenting as chronic meningitis. ( 24355206 )
2014
28
Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis. ( 24101832 )
2013
29
Chronic meningitis caused by Eikenella corrodens. ( 23906239 )
2013
30
Chronic meningitis and central nervous system vasculopathy related to Epstein Barr virus. ( 23349599 )
2012
31
Dementia, peripheral neuropathy, and chronic meningitis in Neurobrucellosis. ( 22499327 )
2012
32
A case of primary diffuse leptomeningeal gliomatosis predominantly involving the cervical spinal cord and mimicking chronic meningitis. ( 22274977 )
2012
33
Chronic meningitis as the first presentation of sarcoidosis: an uncommon finding. ( 24250841 )
2011
34
Chronic meningitis: a diagnostic challenge highlighted in a case of cryptococcal meningoencephalitis in an apparently immunocompetent older woman. ( 22675017 )
2011
35
Quantification of cerebrospinal fluid lactic acid in the differential diagnosis between HIV chronic meningitis and opportunistic meningitis. ( 21345043 )
2011
36
Investigating chronic meningitis. ( 19770493 )
2009
37
Chronic meningitis. ( 19224317 )
2009
38
Chronic meningitis by histoplasmosis: report of a child with acute myeloid leukemia. ( 19287853 )
2008
39
Detection of Cysticercus antigens and antibodies in cerebrospinal fluid of patients with chronic meningitis. ( 18026642 )
2007
40
Chronic meningitis and lacunar stroke in Fabry disease. ( 17940724 )
2007
41
Chronic meningitis caused by Erysipelothrix rhusiopathiae. ( 17893181 )
2007
42
Chronic meningitis and thalamic involvement in a woman: Fabry disease expanding phenotype. ( 17702786 )
2007
43
Primary diffuse leptomeningeal gliomatosis: report of a case presenting with chronic meningitis. ( 20396508 )
2006
44
Chronic meningitis in Thailand. Clinical characteristics, laboratory data and outcome in patients with specific reference to tuberculosis and cryptococcosis. ( 16254452 )
2006
45
Late-onset eosinophilic chronic meningitis occurring 30 years after Taenia solium infestation in a white Caucasian woman. ( 16253336 )
2006
46
Chronic meningitis. ( 16263053 )
2005
47
Difficulty in diagnosing chronic meningitis caused by capsule-deficient Cryptococcus neoformans. ( 16170098 )
2005
48
Chronic meningitis in an immunocompetent adult caused by Cryptococcus neoformans var gatti. ( 17642758 )
2004
49
An unusual case of chronic meningitis. ( 15469610 )
2004
50
Cognitive decline with chronic meningitis secondary to a COX-2 inhibitor. ( 15151910 )
2004

Variations for Chronic Meningitis

Expression for Chronic Meningitis

Search GEO for disease gene expression data for Chronic Meningitis.

Pathways for Chronic Meningitis

GO Terms for Chronic Meningitis

Biological processes related to Chronic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.43 CCL11 IL5 MMP9
2 response to radiation GO:0009314 9.16 CCL11 SNAI2
3 positive regulation of cell migration GO:0030335 9.13 CCL11 MMP9 SNAI2
4 inflammatory response GO:0006954 8.92 CCL11 CRP IL5 NLRP3

Molecular functions related to Chronic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 CRP MMP9 NLRP3 YWHAB

Sources for Chronic Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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