MCID: CHR091
MIFTS: 32

Chronic Meningitis

Categories: Neuronal diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Chronic Meningitis

MalaCards integrated aliases for Chronic Meningitis:

Name: Chronic Meningitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10341
ICD10 33 G03.1
ICD9CM 35 322.2
SNOMED-CT 68 21664006
UMLS 73 C0154653

Summaries for Chronic Meningitis

MalaCards based summary : Chronic Meningitis is related to meningitis and pneumonia. An important gene associated with Chronic Meningitis is NLRP3 (NLR Family Pyrin Domain Containing 3), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and IL4-mediated signaling events. Affiliated tissues include brain, myeloid and liver, and related phenotype is immune system.

Related Diseases for Chronic Meningitis

Diseases in the Meningitis family:

Viral Meningitis Chronic Meningitis
Bacterial Meningitis

Diseases related to Chronic Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 120)
# Related Disease Score Top Affiliating Genes
1 meningitis 30.8 CRP MMP9 NLRP3
2 pneumonia 29.3 CCL11 CRP IL5
3 cinca syndrome 11.1
4 familial cold autoinflammatory syndrome 2 10.6 CRP NLRP3
5 cryopyrin-associated periodic syndrome 10.6 CRP NLRP3
6 muckle-wells syndrome 10.6 CRP NLRP3
7 japanese spotted fever 10.6 CCL11 CRP
8 skeletal tuberculosis 10.6 CRP NLRP3
9 exanthem 10.5 CRP NLRP3
10 pericardial effusion 10.5 CRP NLRP3
11 pemphigoid gestationis 10.5 CCL11 IL5
12 multicentric castleman disease 10.5 CRP IL5
13 mesenteric lymphadenitis 10.5 CRP IL5
14 cellulitis 10.4 CRP IL5
15 strongyloidiasis 10.4 CCL11 IL5
16 eosinophilic gastroenteritis 10.4 CCL11 IL5
17 chronic eosinophilic pneumonia 10.4 CCL11 IL5
18 gastrointestinal allergy 10.4 CCL11 IL5
19 chronic conjunctivitis 10.4 CCL11 IL5
20 eosinophilic gastritis 10.4 CCL11 IL5
21 kimura disease 10.4 CCL11 IL5
22 folliculitis 10.4 CCL11 IL5
23 esophagitis, eosinophilic, 1 10.4 CCL11 IL5
24 pulmonary eosinophilia 10.4 CCL11 IL5
25 diverticulitis 10.4 CRP MMP9
26 eosinophilic pneumonia 10.4 CCL11 IL5
27 blepharitis 10.4 CCL11 MMP9
28 dirofilariasis 10.3 CRP MT-CO1
29 onchocerciasis 10.3 CCL11 IL5
30 allergic conjunctivitis 10.3 CCL11 IL5
31 nasal cavity disease 10.3 CCL11 IL5
32 pelvic inflammatory disease 10.3 CRP MMP9
33 venous insufficiency 10.3 CRP MMP9
34 paragonimiasis 10.3 IL5 MT-CO1
35 scleritis 10.3 IL5 MMP9
36 nose disease 10.3 CCL11 IL5
37 cercarial dermatitis 10.3 IL5 MT-CO1
38 common cold 10.3 CCL11 IL5
39 familial mediterranean fever 10.3 CRP NLRP3
40 upper respiratory tract disease 10.3 CCL11 IL5
41 norwegian scabies 10.3 IL5 MT-CO1
42 appendicitis 10.2 CRP MMP9
43 keratoconjunctivitis 10.2 CCL11 IL5
44 carotid artery disease 10.2 CRP MMP9
45 chorioamnionitis 10.2 CRP MMP9
46 echinococcosis 10.2 IL5 MT-CO1
47 carotid stenosis 10.2 CRP MMP9
48 bone inflammation disease 10.2 CRP NLRP3
49 aortic disease 10.2 CRP MMP9
50 parasitic helminthiasis infectious disease 10.2 IL5 MT-CO1

Comorbidity relations with Chronic Meningitis via Phenotypic Disease Network (PDN):


Acute Cystitis Meningitis

Graphical network of the top 20 diseases related to Chronic Meningitis:



Diseases related to Chronic Meningitis

Symptoms & Phenotypes for Chronic Meningitis

MGI Mouse Phenotypes related to Chronic Meningitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.17 CCL11 CRP IL5 MMP9 MT-CO1 NLRP3

Drugs & Therapeutics for Chronic Meningitis

Search Clinical Trials , NIH Clinical Center for Chronic Meningitis

Genetic Tests for Chronic Meningitis

Anatomical Context for Chronic Meningitis

MalaCards organs/tissues related to Chronic Meningitis:

41
Brain, Myeloid, Liver, Eye, T Cells, Spinal Cord

Publications for Chronic Meningitis

Articles related to Chronic Meningitis:

(show top 50) (show all 112)
# Title Authors Year
1
Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing. ( 29710329 )
2018
2
What's Next (Generation) for the Diagnosis of Chronic Meningitis? ( 29710076 )
2018
3
Chronic Meningitis and Hydrocephalus due to <i>Sporothrix brasiliensis</i> in Immunocompetent Adults: A Challenging Entity. ( 29977951 )
2018
4
A Woman in Her 60s With Chronic Meningitis. ( 28114658 )
2017
5
Tracing the footprints: A case of chronic meningitis with unusual mononuclear cells in the cerebrospinal fluid. ( 28188694 )
2017
6
The Upside of Bias: A Case of Chronic Meningitis Due to Sporothrix Schenckii in an Immunocompetent Host. ( 28042367 )
2017
7
Primary central nervous system natural killer/T-cell lymphoma: An atypical case of chronic meningitis. ( 28222909 )
2017
8
Many faces of neurosarcoidosis: from chronic meningitis to myelopathy. ( 28598872 )
2017
9
Chronic Meningitis: Simplifying a Diagnostic Challenge. ( 26888190 )
2016
10
Chronic meningitis, hydrocephalus and spinal paraplegia in non-systemic histoplasmosis. ( 27338647 )
2016
11
An unusual case of chronic meningitis due to histiocytic sarcoma of the central nervous system with meningeal dissemination. ( 27325388 )
2016
12
Mycobacterium abscessus as a Cause of Chronic Meningitis: A Rare Clinical Entity. ( 27079354 )
2016
13
Neurobrucellosis: an often forgotten cause of chronic meningitis. ( 26160851 )
2015
14
Gliomatosis cerebri with spinal metastasis presenting with chronic meningitis in two boys. ( 26318497 )
2015
15
A 7-year-old girl with recurrent episodes of abdominal pain, seizures, and loss of vision: Primary diffuse leptomeningeal primitive neuroectodermal tumor masquerading as chronic meningitis. ( 26448234 )
2015
16
Chronic Meningitis Complicating Intracranial Hypertension in Neurobrucellosis: A Case Report. ( 24506671 )
2014
17
Hydrocephalus secondary to chronic meningitis. ( 24479823 )
2014
18
Chronic meningitis with intracranial hypertension and bilateral neuroretinitis following Mycoplasma pneumoniae infection. ( 25538215 )
2014
19
Diffusion tensor imaging study of white matter damage in chronic meningitis. ( 24892826 )
2014
20
Chronic meningitis in immunocompromised adult Ethiopians visiting Tikur Anbessa Teaching Hospital and Ye'huleshet Clinic from 2003-2004. ( 24696988 )
2014
21
Evaluation and treatment of chronic meningitis. ( 25360204 )
2014
22
Chronic meningitis in systemic lupus erythematosus: An unusual etiology. ( 25506165 )
2014
23
Chronic meningitis caused by Eikenella corrodens. ( 23906239 )
2013
24
Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis. ( 24101832 )
2013
25
Primary leptomeningeal melanocytosis presenting as chronic meningitis. ( 24355206 )
2013
26
Dementia, peripheral neuropathy, and chronic meningitis in Neurobrucellosis. ( 22499327 )
2012
27
A case of primary diffuse leptomeningeal gliomatosis predominantly involving the cervical spinal cord and mimicking chronic meningitis. ( 22274977 )
2012
28
Chronic meningitis and central nervous system vasculopathy related to Epstein Barr virus. ( 23349599 )
2012
29
Chronic meningitis: a diagnostic challenge highlighted in a case of cryptococcal meningoencephalitis in an apparently immunocompetent older woman. ( 22675017 )
2011
30
Chronic meningitis as the first presentation of sarcoidosis: an uncommon finding. ( 24250841 )
2011
31
Quantification of cerebrospinal fluid lactic acid in the differential diagnosis between HIV chronic meningitis and opportunistic meningitis. ( 21345043 )
2011
32
Investigating chronic meningitis. ( 19770493 )
2009
33
Chronic meningitis. ( 19224317 )
2009
34
Chronic meningitis by histoplasmosis: report of a child with acute myeloid leukemia. ( 19287853 )
2008
35
Chronic meningitis and thalamic involvement in a woman: Fabry disease expanding phenotype. ( 17702786 )
2007
36
Chronic meningitis caused by Erysipelothrix rhusiopathiae. ( 17893181 )
2007
37
Detection of Cysticercus antigens and antibodies in cerebrospinal fluid of patients with chronic meningitis. ( 18026642 )
2007
38
Chronic meningitis and lacunar stroke in Fabry disease. ( 17940724 )
2007
39
Late-onset eosinophilic chronic meningitis occurring 30 years after Taenia solium infestation in a white Caucasian woman. ( 16253336 )
2006
40
Chronic meningitis in Thailand. Clinical characteristics, laboratory data and outcome in patients with specific reference to tuberculosis and cryptococcosis. ( 16254452 )
2006
41
Primary diffuse leptomeningeal gliomatosis: report of a case presenting with chronic meningitis. ( 20396508 )
2006
42
Chronic meningitis. ( 16263053 )
2005
43
Difficulty in diagnosing chronic meningitis caused by capsule-deficient Cryptococcus neoformans. ( 16170098 )
2005
44
Cognitive decline with chronic meningitis secondary to a COX-2 inhibitor. ( 15151910 )
2004
45
Chronic meningitis in an immunocompetent adult caused by Cryptococcus neoformans var gatti. ( 17642758 )
2004
46
Successful treatment of chronic meningitis caused by Scedosporium apiospermum with oral voriconazole. ( 15132423 )
2004
47
An unusual case of chronic meningitis. ( 15469610 )
2004
48
Chronic meningitis. ( 12881801 )
2003
49
Chronic meningitis: still a diagnostic challenge. ( 12796824 )
2003
50
Neonate with chronic meningitis and hydrocephalus. ( 14628782 )
2003

Variations for Chronic Meningitis

Expression for Chronic Meningitis

Search GEO for disease gene expression data for Chronic Meningitis.

Pathways for Chronic Meningitis

GO Terms for Chronic Meningitis

Biological processes related to Chronic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.43 CCL11 IL5 MMP9
2 response to radiation GO:0009314 9.16 CCL11 SNAI2
3 positive regulation of cell migration GO:0030335 9.13 CCL11 MMP9 SNAI2
4 inflammatory response GO:0006954 8.92 CCL11 CRP IL5 NLRP3

Molecular functions related to Chronic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 CRP MMP9 NLRP3 YWHAB

Sources for Chronic Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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