MCID: CHR093
MIFTS: 22

Chronic Orbital Inflammation

Categories: Bone diseases, Eye diseases

Aliases & Classifications for Chronic Orbital Inflammation

MalaCards integrated aliases for Chronic Orbital Inflammation:

Name: Chronic Orbital Inflammation 12 15
Chronic Inflammation of Orbit 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1397
ICD9CM 34 376.1
SNOMED-CT 67 44729001
ICD10 32 H05.1
UMLS 71 C0155261

Summaries for Chronic Orbital Inflammation

MalaCards based summary : Chronic Orbital Inflammation, also known as chronic inflammation of orbit, is related to orbital cancer and anca-associated vasculitis. An important gene associated with Chronic Orbital Inflammation is KNTC1 (Kinetochore Associated 1), and among its related pathways/superpathways is Inflammatory Response Pathway. Affiliated tissues include eye, bone and thyroid.

Related Diseases for Chronic Orbital Inflammation

Diseases in the Acute Orbital Inflammation family:

Chronic Orbital Inflammation

Diseases related to Chronic Orbital Inflammation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 253)
# Related Disease Score Top Affiliating Genes
1 orbital cancer 10.4 PRTN3 KNTC1
2 anca-associated vasculitis 10.4 PRTN3 CTLA4
3 skin sarcoidosis 10.3 TNFRSF1B CTLA4
4 orbital granuloma 10.3 PRTN3 CRP
5 tolosa-hunt syndrome 10.3 PRTN3 CRP
6 bicipital tenosynovitis 10.3 PRTN3 CRP
7 granulomatous angiitis 10.3 PRTN3 CRP
8 esophageal tuberculosis 10.3 TNFRSF1B CTLA4
9 cholesterol embolism 10.3 PRTN3 CRP
10 rheumatoid arthritis interstitial lung disease 10.3 TNFRSF1B CRP
11 ankylosing spondylitis 1 10.3 TNFRSF1B CRP
12 cogan syndrome 10.3 PRTN3 CRP
13 nocardiosis 10.3 TNFRSF1B CRP
14 allergic cutaneous vasculitis 10.3 PRTN3 CD40LG
15 neurosarcoidosis 10.2 TNFRSF1B CRP
16 glossopharyngeal nerve paralysis 10.2 TNFRSF1B CD40LG
17 autoimmune vasculitis 10.2 PRTN3 CRP
18 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.2 TSHR CTLA4
19 hyperglobulinemic purpura 10.2 TNFRSF1B CD40LG
20 myxedema 10.2 TSHR CTLA4
21 spotted fever 10.2 CTLA4 CD40LG
22 granulomatous dermatitis 10.2 TNFRSF1B CD40LG
23 tracheal stenosis 10.2 RHNO1 PRTN3
24 excessive tearing 10.2 TSHR RHNO1
25 cartilage disease 10.2 TNFRSF1B CRP
26 nasopharyngitis 10.2 TNFRSF1B CRP
27 acute maxillary sinusitis 10.2 RHNO1 CRP
28 intestinal perforation 10.2 CTLA4 CRP
29 sphenoid sinusitis 10.2 RHNO1 CRP
30 japanese spotted fever 10.2 CRP CD40LG
31 cavernous sinus thrombosis 10.1 RHNO1 CRP
32 autoimmune disease of urogenital tract 10.1 PRTN3 CD40LG
33 subdural empyema 10.1 RHNO1 CRP
34 intracranial sinus thrombosis 10.1 RHNO1 CRP
35 splenic abscess 10.1 CRP CD40LG
36 meningovascular neurosyphilis 10.1 CRP CD40LG
37 subacute thyroiditis 10.1 TSHR CRP
38 orchitis 10.1 CRP CD40LG
39 viral exanthem 10.1 CRP CD40LG
40 tertiary syphilis 10.1 CRP CD40LG
41 acrodermatitis 10.1 TNFRSF1B CD40LG
42 acalculous cholecystitis 10.1 CRP CD40LG
43 gastrointestinal tuberculosis 10.1 CRP CD40LG
44 epiglottitis 10.1 CRP CD40LG
45 evans' syndrome 10.1 CTLA4 CD40LG
46 viral laryngitis 10.1 CRP CD40LG
47 laryngitis 10.1 CRP CD40LG
48 klebsiella pneumonia 10.1 CRP CD40LG
49 mediastinitis 10.1 RHNO1 CRP
50 ornithosis 10.1 CRP CD40LG

Graphical network of the top 20 diseases related to Chronic Orbital Inflammation:



Diseases related to Chronic Orbital Inflammation

Symptoms & Phenotypes for Chronic Orbital Inflammation

Drugs & Therapeutics for Chronic Orbital Inflammation

Search Clinical Trials , NIH Clinical Center for Chronic Orbital Inflammation

Genetic Tests for Chronic Orbital Inflammation

Anatomical Context for Chronic Orbital Inflammation

MalaCards organs/tissues related to Chronic Orbital Inflammation:

40
Eye, Bone, Thyroid

Publications for Chronic Orbital Inflammation

Articles related to Chronic Orbital Inflammation:

# Title Authors PMID Year
1
Chronic Orbital Inflammation Associated to Hydroxyapatite Implants in Anophthalmic Sockets. 61
29515429 2017
2
Enlargement of the infraorbital nerve: an important sign associated with orbital reactive lymphoid hyperplasia or immunoglobulin g4-related disease. 61
24613826 2014
3
Selenium supplementation in thyroid associated ophthalmopathy: an update. 61
24790886 2014
4
Orbital inflammation in IgG4-related sclerosing disease. 61
21957960 2011
5
[Chronic or subacute orbital inflammation (inflammatory pseudotumors)]. 61
20334884 2010
6
Chronic orbital inflammation and fibrosis after retrobulbar alcohol and chlorpromazine injections in a patient with choroidal melanoma. 61
18806668 2008
7
Treatment of intraorbital lesions using the Accuray CyberKnife system. 61
18415869 2008
8
Magnetic resonance imaging features of orbital inflammation with intracranial extension in four dogs. 61
17899971 2007
9
Sinuorbital complications after intranasal cocaine abuse. 61
15545138 2004
10
Mouse exophthalmic chronic orbital inflammatory disease. Induction by human leucocyte intracellular Mollicutes. 61
3140479 1988

Variations for Chronic Orbital Inflammation

Expression for Chronic Orbital Inflammation

Search GEO for disease gene expression data for Chronic Orbital Inflammation.

Pathways for Chronic Orbital Inflammation

Pathways related to Chronic Orbital Inflammation according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.14 TNFRSF1B CD40LG

GO Terms for Chronic Orbital Inflammation

Biological processes related to Chronic Orbital Inflammation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of T cell proliferation GO:0042129 8.62 TNFRSF1B CTLA4

Sources for Chronic Orbital Inflammation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....