MCID: CHR093
MIFTS: 25

Chronic Orbital Inflammation

Categories: Eye diseases

Aliases & Classifications for Chronic Orbital Inflammation

MalaCards integrated aliases for Chronic Orbital Inflammation:

Name: Chronic Orbital Inflammation 12 15
Chronic Inflammation of Orbit 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:1397
ICD9CM 36 376.1 376.10
SNOMED-CT 69 44729001
ICD10 34 H05.1
UMLS 74 C0155261

Summaries for Chronic Orbital Inflammation

MalaCards based summary : Chronic Orbital Inflammation, also known as chronic inflammation of orbit, is related to rectum squamous cell carcinoma and benign struma ovarii. An important gene associated with Chronic Orbital Inflammation is TSHR (Thyroid Stimulating Hormone Receptor), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Allograft rejection. Affiliated tissues include eye, and related phenotypes are Decreased IL-8 secretion and Decreased viability

Related Diseases for Chronic Orbital Inflammation

Diseases in the Acute Orbital Inflammation family:

Chronic Orbital Inflammation

Diseases related to Chronic Orbital Inflammation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Related Disease Score Top Affiliating Genes
1 rectum squamous cell carcinoma 10.4 SMUG1 TNFRSF1B
2 benign struma ovarii 10.4 SMUG1 TSHR
3 chondromalacia 10.4 SMUG1 TNFRSF1B
4 juvenile ankylosing spondylitis 10.4 MRAP TNFRSF1B
5 scleral disease 10.4 MRAP TNFRSF1B
6 pustulosis of palm and sole 10.4 MRAP TNFRSF1B
7 iritis 10.4 MRAP TNFRSF1B
8 tenosynovitis 10.4 MRAP TNFRSF1B
9 aortitis 10.4 MRAP SMUG1
10 pericoronitis 10.3 NCAM1 TNFRSF1B
11 rhinoscleroma 10.3 NCAM1 TNFRSF1B
12 cryptogenic organizing pneumonia 10.3 MUC1 PIK3C2A
13 sarcomatoid renal cell carcinoma 10.3 IFNA2 MUC1
14 pericardium disease 10.3 PIK3C2A SMUG1
15 gallbladder small cell carcinoma 10.3 NCAM1 SMUG1
16 plexopathy 10.3 PIK3C2A SMUG1
17 ovarian serous cystadenofibroma 10.3 MUC1 NCAM1
18 penile disease 10.3 IFNA2 MRAP
19 transitional meningioma 10.3 MUC1 NCAM1
20 mediastinal cancer 10.3 NCAM1 SMUG1
21 peroneal neuropathy 10.3 MME TNFRSF1B
22 chickenpox 10.3 MUC1 TNFRSF1B
23 myxopapillary ependymoma 10.3 MUC1 NCAM1
24 adenofibroma 10.3 MME MUC1
25 conjunctival disease 10.3 IFNA2 MRAP
26 middle ear carcinoma 10.2 CSF3 SMUG1
27 ovarian squamous cell carcinoma 10.2 CSF3 SMUG1
28 perineurioma 10.2 MUC1 NCAM1
29 postsurgical hypothyroidism 10.2 CSF3 TSHR
30 lung combined type small cell carcinoma 10.2 MME NCAM1
31 extrahepatic bile duct adenocarcinoma 10.2 MME NCAM1
32 myxedema 10.2 CTLA4 TSHR
33 adenomyoma 10.2 MME MUC1
34 hypersensitivity reaction type iv disease 10.2 MRAP SMUG1 TNFRSF1B
35 central nervous system hematologic cancer 10.2 MME SMUG1
36 perivascular epithelioid cell tumor 10.2 MME MUC1
37 mucinous tubular and spindle renal cell carcinoma 10.2 MME MUC1
38 panuveitis 10.2 MRAP TNFRSF1B
39 spermatocele 10.2 MME NCAM1
40 rete testis neoplasm 10.2 MME NCAM1
41 mixed ductal-endocrine carcinoma 10.2 MUC1 NCAM1
42 meningeal melanocytoma 10.2 MME MUC1
43 adult lymphoma 10.2 CSF3 SMUG1
44 pancreatic mucinous cystadenoma 10.2 MME MUC1
45 cogan syndrome 10.2 SMUG1 TNFRSF1B
46 lung lymphoma 10.2 NCAM1 SMUG1
47 acute salpingitis 10.1 MME MRAP TNFRSF1B
48 mammary paget's disease 10.1 CTLA4 MUC1
49 mycosis fungoides 10.1 CTLA4 IFNA2 TNFRSF1B
50 histrionic personality disorder 10.1 KNTC1 MME

Graphical network of the top 20 diseases related to Chronic Orbital Inflammation:



Diseases related to Chronic Orbital Inflammation

Symptoms & Phenotypes for Chronic Orbital Inflammation

GenomeRNAi Phenotypes related to Chronic Orbital Inflammation according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased IL-8 secretion GR00386-A-2 9.5 CSF3 CTLA4 CYCS MME MUC1 NCAM1
2 Decreased viability GR00055-A-2 9.44 MUC1 NCAM1 PIK3C2A
3 Decreased viability GR00221-A-1 9.44 PIK3C2A
4 Decreased viability GR00221-A-2 9.44 PIK3C2A
5 Decreased viability GR00221-A-4 9.44 PIK3C2A
6 Decreased viability GR00240-S-1 9.44 PIK3C2A
7 Decreased viability GR00342-S-1 9.44 PIK3C2A
8 Decreased viability GR00342-S-2 9.44 PIK3C2A
9 Decreased viability GR00342-S-3 9.44 PIK3C2A
10 Decreased viability GR00402-S-2 9.44 MUC1 NCAM1 PIK3C2A

MGI Mouse Phenotypes related to Chronic Orbital Inflammation:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.23 CSF3 CTLA4 CYCS MME PIK3C2A PRTN3

Drugs & Therapeutics for Chronic Orbital Inflammation

Search Clinical Trials , NIH Clinical Center for Chronic Orbital Inflammation

Genetic Tests for Chronic Orbital Inflammation

Anatomical Context for Chronic Orbital Inflammation

MalaCards organs/tissues related to Chronic Orbital Inflammation:

42
Eye

Publications for Chronic Orbital Inflammation

Articles related to Chronic Orbital Inflammation:

# Title Authors Year
1
Chronic Orbital Inflammation Associated to Hydroxyapatite Implants in Anophthalmic Sockets. ( 29515429 )
2017
2
Chronic orbital inflammation and fibrosis after retrobulbar alcohol and chlorpromazine injections in a patient with choroidal melanoma. ( 18806668 )
2008

Variations for Chronic Orbital Inflammation

Expression for Chronic Orbital Inflammation

Search GEO for disease gene expression data for Chronic Orbital Inflammation.

Pathways for Chronic Orbital Inflammation

GO Terms for Chronic Orbital Inflammation

Cellular components related to Chronic Orbital Inflammation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.32 CTLA4 KNTC1 MME MRAP MUC1 NCAM1

Biological processes related to Chronic Orbital Inflammation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.02 CSF3 IFNA2 MUC1 PRTN3 TNFRSF1B

Sources for Chronic Orbital Inflammation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....