MCID: CHR099
MIFTS: 31

Chronic Salpingitis

Categories: Reproductive diseases

Aliases & Classifications for Chronic Salpingitis

MalaCards integrated aliases for Chronic Salpingitis:

Name: Chronic Salpingitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5731
ICD10 33 N70.11
NCIt 50 C40118
SNOMED-CT 68 55551005
UMLS 73 C0269041

Summaries for Chronic Salpingitis

MalaCards based summary : Chronic Salpingitis is related to salpingitis and chlamydia. An important gene associated with Chronic Salpingitis is OVGP1 (Oviductal Glycoprotein 1), and among its related pathways/superpathways are PI3K-Akt signaling pathway and TNFR1 Pathway. Related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Chronic Salpingitis

Diseases in the Salpingitis family:

Acute Salpingitis Chronic Salpingitis

Diseases related to Chronic Salpingitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 salpingitis 31.3 CD79A OVGP1
2 chlamydia 30.4 CD79A MCL1 TNF
3 salpingitis isthmica nodosa 28.7 AVPR2 CD79A HSPA4 KANTR
4 chronic salpingo-oophoritis 11.5
5 acute gonococcal salpingitis 10.9 CTSA TNF
6 skin sarcoidosis 10.7 TNF TNFRSF1B
7 retinitis pigmentosa 75 10.7 TNF TNFRSF1A
8 rheumatoid lung disease 10.7 TNF TNFRSF1B
9 scleral disease 10.6 TNF TNFRSF1B
10 fallopian tube disease 10.6 CD79A OVGP1
11 necrobiosis lipoidica 10.6 SLC2A1 TNFRSF1B
12 pustulosis of palm and sole 10.6 TNF TNFRSF1B
13 periodic fever, familial, autosomal dominant 10.6 TNF TNFRSF1A TNFRSF1B
14 atrophy of prostate 10.6 SLC2A1 TP53
15 post-transplant lymphoproliferative disease 10.6 TNF TNFRSF1A TNFRSF1B
16 palindromic rheumatism 10.6 TNF TNFRSF1A TNFRSF1B
17 farmer's lung 10.5 CD79A TNF
18 peroneal neuropathy 10.5 TNF TNFRSF1B
19 hypersensitivity reaction type iv disease 10.4 CD79A TNF TNFRSF1B
20 exanthem 10.4 CD79A TNF TNFRSF1B
21 epidermal appendage tumor 10.4 CLEC2A TP53
22 spondyloarthropathy 1 10.4 CD79A TNF TNFRSF1B
23 primary bacterial infectious disease 10.4 CD79A TNF TNFRSF1B
24 pericoronitis 10.4 TNFRSF1A TNFRSF1B
25 bone inflammation disease 10.3 CD79A TNF TNFRSF1B
26 lichen disease 10.3 CD79A TNF TP53
27 vasculitis 10.3 CD79A TNF TNFRSF1B
28 trench fever 10.3 KANTR TNF
29 thyroid lymphoma 10.3 TNF TP53
30 cicatricial entropion 10.3 CD79A KANTR
31 substernal goiter 10.2 CD79A KANTR
32 testicular trophoblastic tumor 10.2 CSH1 CSH2
33 glomangiosarcoma 10.2 KANTR TP53
34 cerebral arteritis 10.2 CD79A KANTR
35 guillain-barre syndrome 10.2 CD79A TNF TNFRSF1A TNFRSF1B
36 geniculate herpes zoster 10.1 CD79A KANTR
37 retinitis pigmentosa 35 10.1 CD79A HSPA4
38 sciatic neuropathy 10.1 KANTR TNFRSF1A TNFRSF1B
39 behcet syndrome 10.1 CD79A TNF TNFRSF1A TNFRSF1B
40 choriocarcinoma of ovary 10.1 CSH1 CSH2
41 parasitic protozoa infectious disease 10.1 CD79A HSPA4 TNF
42 lichen sclerosus 10.1 TNF TP53
43 intestinal disease 10.0 CD79A TNF TNFRSF1B TP53
44 uterine anomalies 9.9 CSH1 CSH2 TNF
45 myeloma, multiple 9.9 CD79A MCL1 TNF TP53
46 female reproductive system disease 9.9 CSH1 CSH2 TNF
47 testicular granulosa cell tumor 9.9 CSH1 CSH2
48 juvenile type testicular granulosa cell tumor 9.8 CSH1 CSH2
49 cogan syndrome 9.8 CD79A HSPA4 TNF TNFRSF1B
50 germ cell and embryonal cancer 9.8 CSH1 CSH2 TP53

Graphical network of the top 20 diseases related to Chronic Salpingitis:



Diseases related to Chronic Salpingitis

Symptoms & Phenotypes for Chronic Salpingitis

GenomeRNAi Phenotypes related to Chronic Salpingitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.47 HRK MCL1 TNF TNFRSF1A TNFRSF1B TP53
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.47 AVPR2 BAK1 HRK MCL1 TNF TNFRSF1A

MGI Mouse Phenotypes related to Chronic Salpingitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.02 BAK1 CD79A CTSA HSPA4 MCL1 SLC2A1
2 hematopoietic system MP:0005397 9.96 TNFRSF1A TNFRSF1B TP53 AVPR2 BAK1 BLK
3 neoplasm MP:0002006 9.63 BAK1 CD79A TNF TNFRSF1A TNFRSF1B TP53
4 renal/urinary system MP:0005367 9.5 AVPR2 BAK1 CD79A CTSA TNFRSF1A TNFRSF1B
5 reproductive system MP:0005389 9.28 BAK1 BLK CTSA HSPA4 MCL1 OVGP1

Drugs & Therapeutics for Chronic Salpingitis

Search Clinical Trials , NIH Clinical Center for Chronic Salpingitis

Genetic Tests for Chronic Salpingitis

Anatomical Context for Chronic Salpingitis

Publications for Chronic Salpingitis

Articles related to Chronic Salpingitis:

(show all 16)
# Title Authors Year
1
Tracing GFP-labeled WJMSCs in vivo using a chronic salpingitis model: an animal experiment. ( 29191249 )
2017
2
Treatment evaluation of Wharton's jelly-derived mesenchymal stem cells using a chronic salpingitis model: an animal experiment. ( 29041961 )
2017
3
An incidental finding of chronic salpingitis complications: Tubo-uterine fistula. ( 28976128 )
2017
4
Isolated Tubal Torsion in Patient With Chronic Salpingitis: A Challenging Diagnosis. ( 27678759 )
2015
5
Therapeutic influence of intraperitoneal injection of Wharton's jelly-derived mesenchymal stem cells on oviduct function and fertility in rats with acute and chronic salpingitis. ( 25966129 )
2015
6
"Tubal ostium sunshine": hysteroscopic sign of chronic salpingitis. ( 23084667 )
2012
7
Detection of Chlamydia trachomatis DNA in archival paraffinized specimens from chronic salpingitis cases using the polymerase chain reaction. ( 10899513 )
2000
8
Presence of the major outer-membrane protein of Chlamydia trachomatis in patients with chronic salpingitis and salpingitis isthmica nodosa with tubal occlusion. ( 9797114 )
1998
9
Humoral immune response to the chlamydial heat shock proteins hsp60 and hsp70 in Chlamydia-associated chronic salpingitis with tubal occlusion. ( 8815069 )
1996
10
Postsalpingostomy intercornual bridging with hematosalpinx, chronic salpingitis and perisalpingeal endometriosis. A case report. ( 1564706 )
1992
11
Chronic salpingitis. ( 5905411 )
1966
12
Adenomatoid tumor of the fallopian tube associated with chronic salpingitis. ( 14771022 )
1950
13
Chronic salpingitis. ( 20284795 )
1947
14
Treatment of chronic salpingitis with benzyl cinnamate ester (Jacobson's solution). ( 20252991 )
1947
15
The Treatment of Acute and Chronic Salpingitis. ( 20322471 )
1942
16
Chronic Salpingitis: Hysterosalpingectomy in Its Operative Treatment. ( 18745558 )
1940

Variations for Chronic Salpingitis

Expression for Chronic Salpingitis

Search GEO for disease gene expression data for Chronic Salpingitis.

Pathways for Chronic Salpingitis

Pathways related to Chronic Salpingitis according to GeneCards Suite gene sharing:

(show all 26)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.8 BAK1 CSH1 CSH2 MCL1 TNF TNFRSF1A
2
Show member pathways
12.74 BAK1 TNF TNFRSF1A TNFRSF1B TP53
3
Show member pathways
12.5 CSH1 CSH2 MCL1 TNF
4
Show member pathways
12.46 BAK1 BLK HRK MCL1 TNF TNFRSF1A
5
Show member pathways
12.45 BAK1 TNF TNFRSF1A TP53
6 12.42 BLK CD79A TNF TNFRSF1A TNFRSF1B
7
Show member pathways
12.36 TNF TNFRSF1A TNFRSF1B TP53
8 12.3 SLC2A1 TNF TNFRSF1A TP53
9 12.03 BAK1 MCL1 TNF TNFRSF1A TNFRSF1B
10 11.87 TNF TNFRSF1A TP53
11
Show member pathways
11.84 TNF TNFRSF1A TNFRSF1B TP53
12
Show member pathways
11.83 SLC2A1 TNF TNFRSF1A
13 11.82 TNF TNFRSF1A TNFRSF1B
14 11.81 MCL1 TNF TNFRSF1B TP53
15
Show member pathways
11.68 BAK1 MCL1 TNFRSF1A
16 11.66 HSPA4 SLC2A1 TP53
17
Show member pathways
11.61 TNF TNFRSF1A TNFRSF1B
18 11.46 TNF TNFRSF1A TNFRSF1B
19 11.46 SLC2A1 TNF TNFRSF1A TNFRSF1B
20 11.4 TNF TNFRSF1A TNFRSF1B
21 11.34 TNF TNFRSF1A TP53
22
Show member pathways
11.26 BAK1 HRK MCL1 TNFRSF1A
23 11.18 TNF TNFRSF1A TNFRSF1B
24 11.13 BAK1 MCL1 SLC2A1 TP53
25 11.06 BAK1 MCL1 TNF TNFRSF1A TP53
26
Show member pathways
10.72 HSPA4 SLC2A1 TNF TNFRSF1A TNFRSF1B

GO Terms for Chronic Salpingitis

Cellular components related to Chronic Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.5 AVPR2 BAK1 CSH1 CSH2 CTSA LARS
2 membrane raft GO:0045121 9.02 CD79A SLC2A1 TNF TNFRSF1A TNFRSF1B

Biological processes related to Chronic Salpingitis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.85 BAK1 HRK MCL1 TNFRSF1A TNFRSF1B TP53
2 regulation of cell proliferation GO:0042127 9.81 BLK TNF TNFRSF1A TNFRSF1B
3 cytokine-mediated signaling pathway GO:0019221 9.72 MCL1 TNF TNFRSF1A TNFRSF1B TP53
4 cellular response to mechanical stimulus GO:0071260 9.67 BAK1 SLC2A1 TNFRSF1A
5 I-kappaB kinase/NF-kappaB signaling GO:0007249 9.61 AVPR2 TNF TNFRSF1A
6 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.54 TNF TNFRSF1B
7 regulation of mitochondrial membrane permeability GO:0046902 9.52 BAK1 TP53
8 positive regulation of ceramide biosynthetic process GO:2000304 9.48 TNF TNFRSF1A
9 death-inducing signaling complex assembly GO:0071550 9.46 TNF TNFRSF1A
10 apoptotic signaling pathway GO:0097190 9.46 BAK1 TNF TNFRSF1A TNFRSF1B
11 positive regulation of release of cytochrome c from mitochondria GO:0090200 9.43 BAK1 HRK TP53
12 regulation of apoptotic process GO:0042981 9.43 BAK1 HRK MCL1 TNFRSF1A TNFRSF1B TP53
13 regulation of establishment of endothelial barrier GO:1903140 9.4 TNF TNFRSF1A
14 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.02 BAK1 MCL1 TNF TNFRSF1A TNFRSF1B

Sources for Chronic Salpingitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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