MCID: CCT001
MIFTS: 25

Cicatricial Ectropion

Categories: Eye diseases

Aliases & Classifications for Cicatricial Ectropion

MalaCards integrated aliases for Cicatricial Ectropion:

Name: Cicatricial Ectropion 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:12782
ICD9CM 35 374.14
SNOMED-CT 68 28914006
UMLS 73 C0155196

Summaries for Cicatricial Ectropion

MalaCards based summary : Cicatricial Ectropion is related to skin disease and ectropion. An important gene associated with Cicatricial Ectropion is TGM1 (Transglutaminase 1). The drugs Fluorouracil and Antimetabolites have been mentioned in the context of this disorder. Affiliated tissues include skin and eye.

Related Diseases for Cicatricial Ectropion

Graphical network of the top 20 diseases related to Cicatricial Ectropion:



Diseases related to Cicatricial Ectropion

Symptoms & Phenotypes for Cicatricial Ectropion

Drugs & Therapeutics for Cicatricial Ectropion

Drugs for Cicatricial Ectropion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluorouracil Approved Phase 2 51-21-8 3385
2 Antimetabolites Phase 2
3 Antimetabolites, Antineoplastic Phase 2
4 Immunosuppressive Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 5-fluorouracil Versus Placebo in Periocular Full Thickness Skin Grafts Recruiting NCT02705352 Phase 2 5-Fluorouracil

Search NIH Clinical Center for Cicatricial Ectropion

Genetic Tests for Cicatricial Ectropion

Anatomical Context for Cicatricial Ectropion

MalaCards organs/tissues related to Cicatricial Ectropion:

41
Skin, Eye

Publications for Cicatricial Ectropion

Articles related to Cicatricial Ectropion:

(show top 50) (show all 82)
# Title Authors Year
1
Reversible cicatricial ectropion associated with EGFR inhibitors. ( 29336655 )
2018
2
Apremilast Use in a Case of Cicatricial Ectropion Secondary to Severe Lamellar Ichthyosis. ( 29346172 )
2018
3
Cicatricial ectropion surgery: a prospective study of long-term symptom control, patient satisfaction and anatomical success. ( 29920894 )
2018
4
Chromomycosis, an unusual cause of cicatricial ectropion: a case report. ( 28380102 )
2017
5
Cicatricial ectropion in a patient treated with dupilumab. ( 29260094 )
2017
6
Cicatricial Ectropion Secondary to Graft-Versus-Host Disease. ( 28746254 )
2017
7
Ablative Fractional Laser Resurfacing With Laser-Assisted Delivery of 5-Fluorouracil for the Treatment of Cicatricial Ectropion and Periocular Scarring. ( 28658179 )
2017
8
Long term follow up of mucous membrane grafting for cicatricial ectropion in Ichthyosis: A case report. ( 28314226 )
2017
9
Cicatricial Ectropion With Topical 5% Fluorouracil Cream. ( 27191780 )
2016
10
Facial Pyoderma Gangrenosum Presenting With Cranial Nerve VII Palsy and Cicatricial Ectropion. ( 27893584 )
2016
11
Lipograft in cicatricial ectropion. ( 27842016 )
2016
12
"Boomerang Technique: " Simple Excision With Periosteal Suspension for Correction of Mild-to-Moderate Cicatricial Ectropion. ( 26859652 )
2016
13
Orbicularis Oculi Myocutaneous Flap for Upper Cicatricial Ectropion. ( 26674895 )
2016
14
Cicatricial ectropion secondary to psoriatic arthritis. ( 25810938 )
2015
15
The hybrid approach for reconstruction of severely destructed lower eyelids: combination of skin grafting, temporary tarsorrhaphy, and autologous fat grafting for cicatricial ectropion after injection of commercial grade silicone. ( 25569426 )
2015
16
Non-surgical treatment of congenital ichthyosis cicatricial ectropion and eyelid retraction using Restylane hyaluronic acid. ( 25639983 )
2015
17
Use of amniotic membrane graft in the surgical management of cicatricial ectropion associated with cetuximab therapy. ( 25576167 )
2015
18
Superficial Temporal Artery Island Flap for Cicatricial Ectropion. ( 26079124 )
2015
19
Surgical Management of Cicatricial Ectropion in Pityriasis Rubra Pilaris. ( 25794020 )
2015
20
Free transplantation of autogenous palmaris longus tendon in the repair of cicatricial ectropion of lower eyelid. ( 24693868 )
2014
21
A simple method for the treatment of cicatricial ectropion and eyelid contraction in patients with periocular burn: Vertical V-Y advancement of the eyelid. ( 25306087 )
2014
22
Cicatricial ectropion in grzybowski type of multiple eruptive keratoacanthomas. ( 24481503 )
2014
23
Bisphosphonate-induced osteonecrosis of the maxilla presenting as a cicatricial ectropion. ( 24922331 )
2014
24
Management of Cicatricial Ectropion Secondary to Pyoderma Gangrenosum. ( 24410585 )
2014
25
Modified Kuhnt-Szymanowski surgical procedure for secondary cicatricial ectropion in a horse. ( 22958337 )
2013
26
Use of hyaluronic acid gel in the management of cicatricial ectropion: results and complications. ( 24063354 )
2013
27
Viability of full-thickness skin grafts used for correction of cicatricial ectropion of lower eyelid in previously irradiated field in the periocular region. ( 22287483 )
2013
28
A novel TGM1 splicing mutation in a collodion baby with cicatricial ectropion. ( 24314425 )
2013
29
Demographic characteristics of patients requiring full-thickness skin grafts for cicatricial ectropion at Duke Eye Center from 2000 to 2010. ( 23138221 )
2012
30
Cicatricial ectropion: a complication of topical 5-fluorouracil. ( 21872544 )
2012
31
A bilateral cicatricial ectropion and bilateral upper lid shortening caused by 5-fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency. ( 21077799 )
2011
32
Mucous membrane graft for cicatricial ectropion in lamellar ichthyosis: an approach revisited. ( 21346670 )
2011
33
The use of fibrin tissue glue in the repair of cicatricial ectropion of the lower eyelid. ( 20622696 )
2010
34
Complications of Cicatricial Ectropion Repair with Pre-Auricular Wolfe Graft. ( 20337312 )
2010
35
Maternal skin allograft for cicatricial ectropion in congenital icthyosis. ( 20090485 )
2010
36
Kindler syndrome causing severe cicatricial ectropion. ( 20592640 )
2010
37
Repair of cicatricial ectropion in a harlequin baby. ( 19683196 )
2009
38
Cicatricial ectropion correction in a patient with pyoderma gangrenosum: case report. ( 19668972 )
2009
39
Reversible cicatricial ectropion precipitated by topical brimonidine eye drops. ( 18209648 )
2008
40
Correction of cicatricial ectropion by autologous fat graft. ( 18293030 )
2008
41
Nonsurgical treatment of cicatricial ectropion with hyaluronic acid filler. ( 18317150 )
2008
42
Cicatricial ectropion associated with treatment of metastatic colorectal cancer with cetuximab. ( 17237696 )
2007
43
Periocular cutaneous toxicity and cicatricial ectropion: a potential class effect of antineoplastic agents that inhibit EGFR signaling. ( 18030130 )
2007
44
Resolution of pityriasis rubra pilaris-induced cicatricial ectropion with systemic low-dose methotrexate. ( 17386290 )
2007
45
Cicatricial ectropion: repair with myocutaneous flaps and canthopexy. ( 16970762 )
2006
46
Cicatricial ectropion due to herpes zoster ophthalmicus. ( 16679689 )
2006
47
Surgical management of cicatricial ectropion following scarring dermatopathies in two dogs. ( 16178849 )
2005
48
Severe post thermal burn cicatricial ectropion with corneal ulceration: an illustrative case. ( 16554865 )
2005
49
Composite Z plasty for cicatricial ectropion of Tessier III cleft. ( 14704563 )
2004
50
Repair of cicatricial ectropion in an infant with harlequin ichthyosis using engineered human skin. ( 12208260 )
2002

Variations for Cicatricial Ectropion

Expression for Cicatricial Ectropion

Search GEO for disease gene expression data for Cicatricial Ectropion.

Pathways for Cicatricial Ectropion

GO Terms for Cicatricial Ectropion

Cellular components related to Cicatricial Ectropion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 8.62 DSG4 TGM1

Biological processes related to Cicatricial Ectropion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.16 DSG4 TGM1
2 cornification GO:0070268 8.96 DSG4 TGM1
3 keratinocyte differentiation GO:0030216 8.62 DSG4 TGM1

Molecular functions related to Cicatricial Ectropion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lyase activity GO:0016829 8.62 CBS UROS

Sources for Cicatricial Ectropion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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