MCID: CLR005
MIFTS: 24

Clear Cell Chondrosarcoma

Categories: Cancer diseases

Aliases & Classifications for Clear Cell Chondrosarcoma

MalaCards integrated aliases for Clear Cell Chondrosarcoma:

Name: Clear Cell Chondrosarcoma 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:5867
NCIt 50 C6475
UMLS 72 C1266167

Summaries for Clear Cell Chondrosarcoma

MalaCards based summary : Clear Cell Chondrosarcoma is related to chondrosarcoma and chondroblastoma, and has symptoms including pain An important gene associated with Clear Cell Chondrosarcoma is SPARC (Secreted Protein Acidic And Cysteine Rich), and among its related pathways/superpathways is Endochondral Ossification. Affiliated tissues include bone, lung and bone marrow.

Related Diseases for Clear Cell Chondrosarcoma

Graphical network of the top 20 diseases related to Clear Cell Chondrosarcoma:



Diseases related to Clear Cell Chondrosarcoma

Symptoms & Phenotypes for Clear Cell Chondrosarcoma

UMLS symptoms related to Clear Cell Chondrosarcoma:


pain

Drugs & Therapeutics for Clear Cell Chondrosarcoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase 2 Study of GDC-0449 in Patients With Advanced Chondrosarcomas Active, not recruiting NCT01267955 Phase 2 Vismodegib

Search NIH Clinical Center for Clear Cell Chondrosarcoma

Genetic Tests for Clear Cell Chondrosarcoma

Anatomical Context for Clear Cell Chondrosarcoma

MalaCards organs/tissues related to Clear Cell Chondrosarcoma:

41
Bone, Lung, Bone Marrow

Publications for Clear Cell Chondrosarcoma

Articles related to Clear Cell Chondrosarcoma:

(show top 50) (show all 129)
# Title Authors PMID Year
1
Conventional chondrosarcoma with focal clear cell change: a clinicopathological and molecular analysis. 38
31297850 2019
2
Outcome of First-Line Systemic Treatment for Unresectable Conventional, Dedifferentiated, Mesenchymal, and Clear Cell Chondrosarcoma. 38
30082492 2019
3
Clear Cell Chondrosarcoma With Chondroblastoma-Like Features: A Case for Team Diagnosis. 38
29774790 2018
4
Clear cell chondrosarcoma of the larynx. 38
30181407 2018
5
Fine needle aspiration biopsy diagnosis of primary clear cell chondrosarcoma: A case report. 38
28925593 2018
6
Periostin expression in neoplastic and non-neoplastic diseases of bone and joint. 38
30202513 2018
7
Reconstruction with iliac pedestal cup and proximal femur tumor prosthesis after wide resection of chondrosarcoma - 10-year follow-up results. 38
29234663 2017
8
Chondroblastoma: An Update. 38
28557595 2017
9
Primary Clear Cell Chondrosarcoma of Thoracic Spine. 38
27577196 2017
10
Clear cell chondrosarcoma proximal femur with secondary aneurysmal component - A rarity. 38
28360507 2017
11
The H3F3 K36M mutant antibody is a sensitive and specific marker for the diagnosis of chondroblastoma. 38
26844533 2016
12
Chondroblastoma: An Unusual Cause Of Shoulder Pain In Adolescence. 38
30151442 2016
13
Clear cell chondrosarcoma calcaneum - a case report and review of literature. 38
25619455 2015
14
ERG expression in chondrogenic bone and soft tissue tumours. 38
25378537 2015
15
Epiphyseal osteosarcoma revisited: four illustrative cases with unusual histopathology and literature review. 38
25244180 2015
16
Delayed diagnosis of clear cell chondrosarcoma after total hip replacement. A case report of a rare entity encountered in common surgery. 38
25198302 2015
17
Clear cell chondrosarcoma: Cytologic findings in six cases. 38
24167115 2014
18
[A case of clear cell chondrosarcoma in nasal septum]. 38
24820502 2014
19
Clear cell chondrosarcoma with secondary aneurysmal bone cyst changes. 38
24664395 2014
20
Multiple or metastatic clear cell chondrosarcoma: a case report. 38
25289140 2014
21
[Clear cell chondrosarcoma of cricoid cartilage: report of a case]. 38
24713250 2014
22
An unusual case of clear cell chondrosarcoma with very late recurrence and lung metastases, 29 years after primary surgery. 38
25143849 2014
23
Primary laryngeal clear cell chondrosarcoma: report of a case and literature review. 38
24715432 2014
24
Advanced chondrosarcomas: role of chemotherapy and survival. 38
24099780 2013
25
The imaging of cartilaginous bone tumours. II. Chondrosarcoma. 38
23053201 2013
26
Epithelial and cartilaginous differentiation in clear cell chondrosarcoma. 38
22944296 2013
27
Clear-cell chondrosarcoma of the humerus. 38
27330631 2013
28
Clear cell chondrosarcoma arising from the sternum: a rare tumor in an uncommon location. 38
22541211 2012
29
Clear cell chondrosarcoma of the head and neck. 38
22520362 2012
30
Response to sunitinib in combination with proton beam radiation in a patient with chondrosarcoma: a case report. 38
22289277 2012
31
Primary clear cell chondrosarcoma of the spine: a case report of a rare entity and a review of the literature. 38
23091759 2012
32
[Clear cell chondrosarcoma without osteoclast-like giant cells: report of a case]. 38
21914353 2011
33
Clear-cell chondrosarcoma of the lumbar spine: case report and review of the literature. 38
21242824 2011
34
Clear cell chondrosarcoma: an ultrastructural study. 38
19784747 2009
35
The clinical approach towards chondrosarcoma. 38
18378543 2008
36
Clear cell chondrosarcoma of bone: long time follow-up of 18 cases. 38
17522879 2008
37
Conventional intramedullary chondrosarcoma with subarticular involvement. 38
18164401 2008
38
Clear cell chondrosarcoma in the nasal septum. 38
18036435 2007
39
[Clear cell chondrosarcoma: report of a case]. 38
17845769 2007
40
[Pathohistology of femoral head necrosis]. 38
17450348 2007
41
Aggressive clear cell chondrosarcomas: do distinctive characteristics exist?: a report of 4 cases. 38
17076530 2006
42
Primary clear-cell chondrosarcoma of the cervical spine. Case illustration. 38
16703913 2006
43
Type II collagen, but not aggrecan expression, distinguishes clear cell chondrosarcoma and chondroblastoma. 38
16484006 2006
44
[Cartilage tumors. Classification, conditions for biopsy and histologic characteristics]. 38
16322881 2005
45
An institutional review of clear cell chondrosarcoma. 38
16239809 2005
46
Cytogenetic findings in clear cell chondrosarcoma. 38
16157204 2005
47
Image features of two rare mediastinal tumors: schwannoma of intrathoracic phrenic nerve and clear cell chondrosarcoma of the rib. 38
16157055 2005
48
Skull metastasis from clear cell chondrosarcoma. 38
16041184 2005
49
[Clear cell chondrosarcoma of the larynx. A rare tumor in an uncommon location]. 38
15316626 2005
50
Clear cell chondrosarcoma of the proximal femur with intrapelvic extension. 38
15558292 2005

Variations for Clear Cell Chondrosarcoma

Expression for Clear Cell Chondrosarcoma

Search GEO for disease gene expression data for Clear Cell Chondrosarcoma.

Pathways for Clear Cell Chondrosarcoma

Pathways related to Clear Cell Chondrosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.44 SOX9 RUNX2

GO Terms for Clear Cell Chondrosarcoma

Cellular components related to Clear Cell Chondrosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet alpha granule lumen GO:0031093 8.62 SPARC SERPINA3

Biological processes related to Clear Cell Chondrosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 skeletal system development GO:0001501 9.4 SOX9 RUNX2
2 platelet degranulation GO:0002576 9.37 SPARC SERPINA3
3 chondrocyte differentiation GO:0002062 9.32 SOX9 RUNX2
4 cellular response to BMP stimulus GO:0071773 9.26 SOX9 RUNX2
5 positive regulation of chondrocyte differentiation GO:0032332 9.16 SOX9 RUNX2
6 chondrocyte development GO:0002063 8.96 SOX9 RUNX2
7 ossification GO:0001503 8.92 SPARC SOX9 RUNX2 EXT2

Molecular functions related to Clear Cell Chondrosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 bHLH transcription factor binding GO:0043425 8.62 SOX9 RUNX2

Sources for Clear Cell Chondrosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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