MCID: CLR013
MIFTS: 26

Clear Cell Hidradenoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Clear Cell Hidradenoma

MalaCards integrated aliases for Clear Cell Hidradenoma:

Name: Clear Cell Hidradenoma 12 15 70
Clear Cell Myoepithelioma 12
Eccrine Acrospiroma 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5443
NCIt 50 C7567
SNOMED-CT 67 254719003
UMLS 70 C0206671 C1370701

Summaries for Clear Cell Hidradenoma

MalaCards based summary : Clear Cell Hidradenoma, also known as clear cell myoepithelioma, is related to malignant acrospiroma and nodular hidradenoma. An important gene associated with Clear Cell Hidradenoma is MAML2 (Mastermind Like Transcriptional Coactivator 2). Affiliated tissues include skin, breast and lymph node.

Related Diseases for Clear Cell Hidradenoma

Diseases related to Clear Cell Hidradenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 300)
# Related Disease Score Top Affiliating Genes
1 malignant acrospiroma 31.1 PIP MAML2 KRT7 KRT5 CEACAM5
2 nodular hidradenoma 30.8 PIP CEACAM5
3 pleomorphic adenoma 30.6 MAML2 KRT7 CRTC1
4 intraductal papilloma 29.9 KRT7 KRT5
5 sebaceous adenocarcinoma 29.9 PIP KRT5
6 mammary paget's disease 29.9 PIP KRT7
7 hidradenoma 29.6 PIP MME MAML2 KRT7 KRT5 CRTC3
8 eccrine acrospiroma 29.4 PIP MAML2 KRT7 KRT5 CEACAM5
9 basal cell carcinoma 29.4 MME KRT7 KRT5 CEACAM5
10 mucoepidermoid carcinoma 28.5 PAX8 MAML2 KRT7 KRT5 CRTC3 CRTC1
11 rare tumor 10.3
12 lacrimal gland mucoepidermoid carcinoma 10.3 MAML2 CRTC1
13 schneiderian carcinoma 10.3 MAML2 CRTC1
14 renal cell carcinoma, nonpapillary 10.3
15 cervical adenosquamous carcinoma 10.3 MAML2 CRTC1
16 fox-fordyce disease 10.2 PIP CEACAM5
17 vulvar eccrine porocarcinoma 10.2 PIP CEACAM5
18 fallopian tube endometriosis 10.2 MME CEACAM5
19 cervical serous adenocarcinoma 10.2 MME CEACAM5
20 mucocele of appendix 10.2 MME CEACAM5
21 anal canal paget's disease 10.2 PIP KRT7
22 gastric signet ring cell adenocarcinoma 10.2 PIP KRT7
23 syringoma 10.2 KRT7 CEACAM5
24 oncocytic breast carcinoma 10.2 PIP KRT7
25 bartholin's gland disease 10.2 PIP KRT7
26 atrophoderma vermiculata 10.2 MME CEACAM5
27 lipoadenoma 10.2 KRT7 CRTC1
28 eyelid carcinoma 10.2 PIP KRT7
29 cervical mucinous adenocarcinoma 10.2 MME KRT7
30 mixed epithelial stromal tumour 10.2 MME KRT7
31 leukoplakia of penis 10.2 KRT7 CEACAM5
32 erysipeloid 10.2 PIP KRT7
33 epididymal neoplasm 10.2 MME KRT7
34 urethral villous adenoma 10.2 KRT7 CEACAM5
35 villous adenoma 10.2 KRT7 CEACAM5
36 adenoma 10.2
37 mucinous adenofibroma 10.2 KRT7 CEACAM5
38 clear cell papillary renal cell carcinoma 10.2 MME KRT7
39 pancreatic foamy gland adenocarcinoma 10.2 KRT7 CEACAM5
40 chromophil adenoma of the kidney 10.2 MME KRT7
41 dacryocystocele 10.2 PIP KRT7
42 chronic inflammation of lacrimal passage 10.2 PIP KRT7
43 urinary bladder villous adenoma 10.2 KRT7 CEACAM5
44 tinea cruris 10.2 PIP KRT7
45 orbital cellulitis 10.2 MME KRT7
46 vaginal tubulovillous adenoma 10.2 KRT7 CEACAM5
47 acute orbital inflammation 10.2 MME KRT7
48 bile duct cystadenocarcinoma 10.2 KRT7 CEACAM5
49 mucinous ovarian cystadenoma 10.2 KRT7 CEACAM5
50 pulmonary artery leiomyosarcoma 10.2 MME KRT7

Graphical network of the top 20 diseases related to Clear Cell Hidradenoma:



Diseases related to Clear Cell Hidradenoma

Symptoms & Phenotypes for Clear Cell Hidradenoma

Drugs & Therapeutics for Clear Cell Hidradenoma

Search Clinical Trials , NIH Clinical Center for Clear Cell Hidradenoma

Genetic Tests for Clear Cell Hidradenoma

Anatomical Context for Clear Cell Hidradenoma

MalaCards organs/tissues related to Clear Cell Hidradenoma:

40
Skin, Breast, Lymph Node, Eye, Smooth Muscle

Publications for Clear Cell Hidradenoma

Articles related to Clear Cell Hidradenoma:

(show top 50) (show all 170)
# Title Authors PMID Year
1
Clear Cell Hidradenoma-Basal Cell Carcinoma Collision. 61
32804693 2021
2
Three Cases of Clear Cell Hidradenoma With "Benign" Lymph Node Involvement. 61
33464750 2021
3
Clear cell papillary neoplasm of the breast with MAML2 gene rearrangement: Clear cell hidradenoma or low-grade mucoepidermoid carcinoma? 61
32853960 2020
4
Perineal Clear Cell Hidradenoma: A GATA3-positive Neoplasm With Potential for Misdiagnosis. 61
32925441 2020
5
Clear Cell Hidradenoma of the Breast Diagnosed on a Core Needle Biopsy: A case report and review of the literature. 61
33110653 2020
6
Clear cell hidradenoma of the hand: A case report in an 83-year old patient. 61
32979831 2020
7
Clear Cell Hidradenoma: Characteristic Imaging Features on Ultrasonography, Computed Tomography, and Magnetic Resonance Imaging. 61
29388236 2018
8
Hidradenoma of the Chin. 61
28570408 2017
9
The utility of using immunohistochemistry in the differentiation of metastatic, cutaneous clear cell renal cell carcinoma and clear cell hidradenoma. 61
28374447 2017
10
Large Eccrine Acrospiroma of the Hand. 61
28892973 2017
11
Malignant Clear Cell Hidradenoma of the Breast. 61
28409065 2017
12
Clear cell hidradenoma of the breast with MAML2 gene rearrangement. 61
27914681 2017
13
Lymph node location of a clear cell hidradenoma: report of a patient and review of literature. 61
27080562 2016
14
Clear Cell Hidradenoma of the Ear Lobule: An Unusual Site of Presentation. 61
26435960 2015
15
Cytological features of malignant eccrine acrospiroma presenting as a soft tissue mass axilla: A rare sweat gland tumor with histologic correlation. 61
26097826 2015
16
Expression and diagnostic implications of carbonic anhydrase IX in several tumours with predominantly clear cell morphology. 61
25431204 2015
17
What is your diagnosis? Clear cell hidradenoma. 61
25566574 2014
18
Balloon cell nevus of the iris. 61
24951244 2014
19
Clear cell hidradenoma on the palm. 61
24966646 2014
20
Clear cell hidradenoma of breast mimicking atypical breast lesion: a diagnostic pitfall in breast cytology. 61
25002948 2014
21
Histopathological study of skin adnexal tumours-institutional study in South India. 61
24649367 2014
22
[Expression of carbonic anhydrase IX, PAX2 and PAX8 and their association with clinicopathologic characteristics in renal epithelial tumors]. 61
24246861 2013
23
Clear cell hidradenoma. 61
24516840 2013
24
Clear cell hidradenoma: An unusual tumor of the oral cavity. 61
23798849 2013
25
Malignant eccrine acrospiroma: a case report. 61
22659768 2012
26
Nodular hidradenoma in a 19-year-old woman. 61
22393689 2011
27
A giant benign clear cell hidradenoma on the anterior trunk. 61
25386297 2011
28
Dermoscopy of eccrine acrospiroma masquerading as nodular malignant melanoma. 61
21390477 2010
29
Giant benign nodular hidradenoma of the shoulder: A rare tumor in orthopedic practice. 61
21655004 2010
30
Giant clear cell hidradenoma of the knee. 61
19615032 2010
31
Clear cell hidradenoma of the axilla: a case report with literature review. 61
20592936 2010
32
A skin tumor in a young girl. Diagnosis: Clear cell hidradenoma. 61
20657141 2010
33
Perianal nodular hidradenocarcinoma. Case report. 61
20478121 2010
34
Immunophenotypic aspects of cylindroma and nodular hidradenoma. 61
19796089 2010
35
Clear-cell hidradenoma in a child: a diagnostic dilemma for the cytopathologist. 61
19459171 2009
36
Apocrine hidradenocarcinoma showing Paget's disease and mucinous metaplasia. 61
19476529 2009
37
Nodular hidradenoma of the breast: A case report with literature review. 61
23133109 2009
38
Clear cell hidradenoma of the gluteal region: a case report. 61
19595274 2009
39
t(11;19) translocation and CRTC1-MAML2 fusion oncogene in mucoepidermoid carcinoma. 61
18486532 2009
40
Cytomorphological diagnosis of malignant eccrine tumors: report of two cases. 61
18831018 2008
41
Clear cell hidradenoma: an unusual vulvar tumor. 61
18580328 2008
42
Adnexal skin tumors in Zaria, Nigeria. 61
18702242 2008
43
Dermoscopic features of clear cell hidradenoma. 61
18663309 2008
44
Malignant clear cell hidradenoma of the vulva: report of a unique case and review of the literature. 61
18156989 2008
45
Clear cell hidradenoma of the ankle. 61
17761324 2007
46
Clear cell hidradenoma in a young boy. 61
17921627 2007
47
Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23). 61
17551948 2007
48
Mucinous hidradenoma: a report of three cases. 61
17518780 2007
49
Clinicopathologic features and BRAF(V600E) mutation analysis in cutaneous metastases from well-differentiated thyroid carcinomas. 61
17387744 2007
50
Metastatic hidradenocarcinoma with demonstration of Her-2/neu gene amplification by fluorescence in situ hybridization: potential treatment implications. 61
17214855 2007

Variations for Clear Cell Hidradenoma

Expression for Clear Cell Hidradenoma

Search GEO for disease gene expression data for Clear Cell Hidradenoma.

Pathways for Clear Cell Hidradenoma

GO Terms for Clear Cell Hidradenoma

Biological processes related to Clear Cell Hidradenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 energy homeostasis GO:0097009 9.16 CRTC3 CRTC1
2 positive regulation of long-term synaptic potentiation GO:1900273 8.96 MME CRTC1
3 positive regulation of CREB transcription factor activity GO:0032793 8.62 CRTC3 CRTC1

Molecular functions related to Clear Cell Hidradenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cAMP response element binding protein binding GO:0008140 8.62 CRTC3 CRTC1

Sources for Clear Cell Hidradenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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