MCID: CLR018
MIFTS: 26

Clear Cell Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Clear Cell Meningioma

MalaCards integrated aliases for Clear Cell Meningioma:

Name: Clear Cell Meningioma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4210
MeSH 44 D008579
NCIt 50 C4722
SNOMED-CT 68 134213009 57606003
UMLS 73 C0431121

Summaries for Clear Cell Meningioma

MalaCards based summary : Clear Cell Meningioma is related to brainstem intraparenchymal clear cell meningioma and spinal multifocal clear cell meningioma. An important gene associated with Clear Cell Meningioma is SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily E, Member 1), and among its related pathways/superpathways is Signaling by ERBB4. The drugs Trabectedin and Alkylating Agents have been mentioned in the context of this disorder. Affiliated tissues include pituitary and bone.

Related Diseases for Clear Cell Meningioma

Diseases related to Clear Cell Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 83)
# Related Disease Score Top Affiliating Genes
1 brainstem intraparenchymal clear cell meningioma 12.3
2 spinal multifocal clear cell meningioma 12.2
3 epithelioid malignant peripheral nerve sheath tumor 10.4 CHGA MUC1
4 meningothelial meningioma 10.3 SMARCE1 SNRPB
5 sclerosing hemangioma 10.3 CHGA MUC1
6 breast mucoepidermoid carcinoma 10.3 MUC1 PGR
7 breast scirrhous carcinoma 10.3 MUC1 PGR
8 endosalpingiosis 10.3 MUC1 PGR
9 gastric tubular adenocarcinoma 10.3 CHGA MUC1
10 malignant mixed mullerian tumor 10.3 MUC1 PGR
11 mixed ductal-endocrine carcinoma 10.3 CHGA MUC1
12 endometrial mucinous adenocarcinoma 10.3 MUC1 PGR
13 apocrine adenocarcinoma 10.3 MUC1 PGR
14 signet ring cell adenocarcinoma 10.3 CHGA MUC1
15 perivascular epithelioid cell tumor 10.2 MUC1 PGR
16 sertoli-leydig cell tumor 10.2 MUC1 PGR
17 chickenpox 10.2 MUC1 PGR
18 breast secretory carcinoma 10.2 MUC1 PGR
19 pancreatic mucinous cystadenoma 10.2 MUC1 PGR
20 benign meningioma 10.2 PGR SMARCE1
21 peritoneal mesothelioma 10.2 MUC1 PGR
22 mammary paget's disease 10.2 MUC1 PGR
23 olfactory groove meningioma 10.1 CHGA PGR
24 pancreatic serous cystadenoma 10.1 CHGA PGR
25 papillary adenocarcinoma 10.1 MUC1 PGR
26 anterior cranial fossa meningioma 10.1 CHGA PGR
27 spindle cell carcinoma 10.1 MUC1 PGR
28 malignant ovarian surface epithelial-stromal neoplasm 10.1 MUC1 PGR
29 ovary epithelial cancer 10.1 MUC1 PGR
30 intracranial cysts 10.0 GFAP MUC1
31 cutaneous leiomyosarcoma 10.0 GFAP MUC1
32 parachordoma 10.0 GFAP MUC1
33 pneumothorax 10.0 MUC1 PGR
34 syringocystadenoma papilliferum 10.0 GFAP MUC1
35 spindle cell rhabdomyosarcoma 10.0 GFAP MUC1
36 myxopapillary ependymoma 10.0 GFAP MUC1
37 chordoid glioma 10.0 GFAP MUC1
38 syringoma 10.0 GFAP MUC1
39 breast papillary carcinoma 10.0 CHGA PGR
40 anaplastic ependymoma 10.0 GFAP MUC1
41 perineurioma 10.0 GFAP MUC1
42 cystadenocarcinoma 10.0 MUC1 PGR
43 papilloma of choroid plexus 10.0 GFAP MUC1
44 merkel cell carcinoma 10.0 CHGA MUC1
45 cellular ependymoma 9.9 CHGA GFAP
46 cell type benign neoplasm 9.9 CHGA SNRPB
47 renal cell carcinoma, nonpapillary 9.9
48 cervicitis 9.9
49 clear cell renal cell carcinoma 9.9
50 ductal carcinoma in situ 9.9 MUC1 PGR

Graphical network of the top 20 diseases related to Clear Cell Meningioma:



Diseases related to Clear Cell Meningioma

Symptoms & Phenotypes for Clear Cell Meningioma

Drugs & Therapeutics for Clear Cell Meningioma

Drugs for Clear Cell Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Trabectedin Approved, Investigational Phase 2 114899-77-3 108150
2 Alkylating Agents Phase 2
3 Antineoplastic Agents, Alkylating Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Trabectedin for Recurrent Grade II/III Meningioma Active, not recruiting NCT02234050 Phase 2 Trabectedin
2 Oncological Care for Patients With Meningioma Not yet recruiting NCT02973256

Search NIH Clinical Center for Clear Cell Meningioma

Genetic Tests for Clear Cell Meningioma

Anatomical Context for Clear Cell Meningioma

MalaCards organs/tissues related to Clear Cell Meningioma:

41
Pituitary, Bone

Publications for Clear Cell Meningioma

Articles related to Clear Cell Meningioma:

(show top 50) (show all 80)
# Title Authors Year
1
Pediatric nondura-based clear cell meningioma of the cauda equina: case report and review of literature. ( 29363346 )
2018
2
SMARCE1 mutation screening in classification of clear cell meningiomas. ( 27891692 )
2017
3
Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis. ( 28474749 )
2017
4
Molecular progression in unusual recurrent non-pediatric intracranial clear cell meningioma. ( 28680293 )
2017
5
Clear-cell meningioma: Intraoperative diagnosis by squash cytology: Case report and review of the literature. ( 28484556 )
2017
6
Clear cell meningioma: A case report with review of the literature. ( 27773164 )
2016
7
Osteolytic clear cell meningioma of the petrous bone occurring 36 years after posterior cranial fossa irradiation: Case report. ( 27375148 )
2016
8
Pediatric intracranial clear cell meningioma: a clinicopathological study of seven cases and literature review. ( 27787647 )
2016
9
Suprasellar Clear Cell Meningioma in an Infant. ( 27606120 )
2016
10
Clinical features of clear cell meningioma: a retrospective study of 36 cases among 10,529 patients in a single institution. ( 26573513 )
2015
11
SMARCE1 mutations in pediatric clear cell meningioma: case report. ( 26114992 )
2015
12
Intrasellar Clear Cell Meningioma Mimicking Invasive Pituitary Adenoma: A Case Report and Review of the Literature. ( 26617154 )
2015
13
Clear cell meningioma in a child: A case report and review of literature. ( 25767587 )
2015
14
Clear cell meningioma: clinical features, CT, and MR imaging findings in 23 patients. ( 24625613 )
2014
15
Pediatric intracranial clear cell meningioma associated with a germline mutation of SMARCE1: a novel case. ( 25249420 )
2014
16
Germline SMARCE1 mutations predispose to both spinal and cranial clear cell meningiomas. ( 25143307 )
2014
17
Spinal Clear Cell Meningioma in a 3-Year-Old: A Case Report. ( 25377168 )
2014
18
A case of clear cell meningioma with tyrosine-rich crystals. ( 23248340 )
2013
19
Nondura-based clear cell meningioma of the cauda equina in an adult. ( 22437332 )
2013
20
An intracranial and intraspinal clear cell meningioma. ( 22727208 )
2013
21
Malignant (anaplastic) transformation of orbital clear cell meningioma. ( 21386740 )
2012
22
Clear cell meningioma masquerading as trigeminal schwannoma. ( 23050207 )
2012
23
Clear-cell meningioma presenting as an infiltrative external auditory canal mass. ( 27326268 )
2012
24
Clear cell meningioma of the cauda equina in an adult. ( 22771665 )
2012
25
Clear cell meningioma with histologically aggressive appearance and clinically aggressive behavior: a case report. ( 22082299 )
2012
26
Paediatric clear cell meningioma with multiple distant recurrences after presumed intra-operative cell spread. ( 22218777 )
2012
27
Intracranial clear cell meningioma in two children with blood relations: two case reports and literature review. ( 22814951 )
2012
28
Intracranial clear cell meningioma: a clinicopathologic study of 15 cases. ( 21643672 )
2011
29
Non-dura based intaspinal clear cell meningioma. ( 21494369 )
2011
30
Clear cell meningioma with frequent chordoid features and aggressive behavior: a clinicopathologic study of ten cases at a single institution. ( 20872042 )
2011
31
The cytology of intracranial clear cell meningioma with an unusual scalp presentation. ( 21897546 )
2011
32
Clear cell meningioma: a clinicopathologic study of 18 tumors and examination of the use of CD10, CA9, and RCC antibodies to distinguish between clear cell meningioma and metastatic clear cell renal cell carcinoma. ( 20453815 )
2010
33
Clear cell meningioma of the fourth ventricle in a child: a case report and literature review. ( 21540624 )
2010
34
Supratentorial clear cell meningioma in a child: A rare tumor at unusual location. ( 21559163 )
2010
35
Clear cell meningioma causing Castleman syndrome in a child. ( 20515337 )
2010
36
Clear cell meningioma with anaplastic features: case report and review of literature. ( 19857933 )
2010
37
[Report of seven cases of clear-cell meningioma and a literature review]. ( 20451062 )
2010
38
An unusual case of clear cell meningioma. ( 20160375 )
2009
39
Extradural middle fossa approach to a clear cell meningioma in a child. ( 19378726 )
2009
40
Posterior fossa clear cell meningioma without dural attachment in a child. ( 19030867 )
2009
41
Clear-cell meningioma of the anterior cranial fossa. Case report and review of the literature. ( 20075823 )
2009
42
Intracranial clear-cell meningioma. ( 19277460 )
2009
43
Clear cell meningioma presenting as rapidly deteriorating visual field and acuity during pregnancy. ( 19632846 )
2009
44
Pediatric spinal clear cell meningioma. Case report. ( 19119906 )
2009
45
Primary clear cell meningioma of the orbit mimicking a metastatic carcinoma: usefulness of immunohistochemistry and cytogenetic analysis. ( 18193452 )
2008
46
An intraventricular clear cell meningioma revealed by an inflammatory syndrome in a male adult: a case report. ( 18514392 )
2008
47
Clear cell meningioma, an uncommon variant of meningioma: a clinicopathologic study of nine cases. ( 16955223 )
2007
48
An unusual case of cervical clear-cell meningioma in pediatric age. ( 17021731 )
2007
49
Frontotemporal clear cell meningioma. Report of 3 cases. ( 17498592 )
2007
50
Intramedullary clear cell meningioma. ( 16341630 )
2006

Variations for Clear Cell Meningioma

Expression for Clear Cell Meningioma

Search GEO for disease gene expression data for Clear Cell Meningioma.

Pathways for Clear Cell Meningioma

Pathways related to Clear Cell Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.66 GFAP PGR

GO Terms for Clear Cell Meningioma

Molecular functions related to Clear Cell Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 8.8 MUC1 PGR SMARCE1

Sources for Clear Cell Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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