MCID: CLR112
MIFTS: 25

Clear Cell Papillary Renal Cell Carcinoma

Categories: Cancer diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Clear Cell Papillary Renal Cell Carcinoma

MalaCards integrated aliases for Clear Cell Papillary Renal Cell Carcinoma:

Name: Clear Cell Papillary Renal Cell Carcinoma 58

Classifications:

Orphanet: 58  
Rare renal diseases


External Ids:

ICD10 via Orphanet 33 C64
Orphanet 58 ORPHA404511

Summaries for Clear Cell Papillary Renal Cell Carcinoma

MalaCards based summary : Clear Cell Papillary Renal Cell Carcinoma is related to adenoma and cystadenoma. An important gene associated with Clear Cell Papillary Renal Cell Carcinoma is HNF1A (HNF1 Homeobox A), and among its related pathways/superpathways is Glucose / Energy Metabolism. Affiliated tissues include kidney, breast and cortex, and related phenotypes are immune system and integument

Related Diseases for Clear Cell Papillary Renal Cell Carcinoma

Diseases related to Clear Cell Papillary Renal Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 118)
# Related Disease Score Top Affiliating Genes
1 adenoma 30.6 VHL KRT7 CDC73
2 cystadenoma 30.2 VHL MME KRT7
3 kidney cancer 30.1 VHL PBRM1 CA9
4 renal adenoma 30.0 TFE3 MME KRT7 AMACR
5 renal cell carcinoma, nonpapillary 29.8 VHL TFE3 PBRM1 MME MITF KRT7
6 clear cell renal cell carcinoma 29.7 VHL TFE3 PBRM1 MME KRT7 HNF1A
7 oncocytoma 29.7 VHL MME KRT7 CA9 AMACR
8 renal cell carcinoma, papillary, 1 29.6 VHL TFE3 PBRM1 MME MITF KRT7
9 angiomyolipoma 29.6 TFE3 MME MITF KRT7
10 chromophil renal cell carcinoma 11.1
11 end stage renal disease 10.8
12 von hippel-lindau syndrome 10.5
13 papillary carcinoma 10.3
14 multilocular cystic renal neoplasm of low malignant potential 10.3
15 rare tumor 10.3
16 nephrogenic adenoma 10.3 KRT7 AMACR
17 clear cell adenocarcinoma 10.3 KRT7 AMACR
18 bladder benign neoplasm 10.3 KRT7 AMACR
19 epithelial predominant wilms' tumor 10.3 KRT7 AMACR
20 mucinous adenocarcinoma 10.3 KRT7 AMACR
21 urethral diverticulum 10.3 KRT7 AMACR
22 glandular cystitis 10.3 KRT7 AMACR
23 urethra clear cell adenocarcinoma 10.2 KRT7 AMACR
24 subareolar duct papillomatosis 10.2 MME KRT7
25 bladder adenocarcinoma 10.2 KRT7 AMACR
26 cervical mucinous adenocarcinoma 10.2 MME KRT7
27 nipple benign neoplasm 10.2 MME KRT7
28 pancreatic serous cystadenocarcinoma 10.2 MME KRT7
29 adenofibroma 10.2 MME KRT7
30 mixed epithelial stromal tumour 10.2 MME KRT7
31 epididymal neoplasm 10.2 MME KRT7
32 ovarian mucinous adenocarcinoma 10.2 KRT7 AMACR
33 wolffian duct adenocarcinoma 10.2 MME KRT7
34 breast metaplastic carcinoma 10.2 MME KRT7
35 orbital cellulitis 10.2 MME KRT7
36 acute orbital inflammation 10.2 MME KRT7
37 seminal vesicle adenocarcinoma 10.2 KRT7 AMACR
38 balloon cell malignant melanoma 10.2 MME KRT7
39 pulmonary artery leiomyosarcoma 10.2 MME KRT7
40 clear cell hidradenoma 10.2 MME KRT7
41 metanephric adenoma 10.2 KRT7 AMACR
42 hidradenoma 10.2 MME KRT7
43 pancreatic mucinous cystadenoma 10.2 MME KRT7
44 cystadenofibroma 10.2 MME KRT7
45 squamous papillomatosis 10.2 MME KRT7
46 cutaneous adenocystic carcinoma 10.2 MME KRT7
47 nasal cavity olfactory neuroblastoma 10.2 MME KRT7
48 nephrogenic adenofibroma 10.2 TFE3 KRT7
49 ovarian sex-cord stromal tumor 10.2 MME KRT7
50 eosinophilic variant of chromophobe renal cell carcinoma 10.2 TFE3 KRT7

Graphical network of the top 20 diseases related to Clear Cell Papillary Renal Cell Carcinoma:



Diseases related to Clear Cell Papillary Renal Cell Carcinoma

Symptoms & Phenotypes for Clear Cell Papillary Renal Cell Carcinoma

MGI Mouse Phenotypes related to Clear Cell Papillary Renal Cell Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.8 CA9 CDC73 MITF MME PBRM1 TFE3
2 integument MP:0010771 9.63 CDC73 HNF1A MITF MME TFE3 VHL
3 liver/biliary system MP:0005370 9.5 AMACR CDC73 HNF1A MITF MME PBRM1
4 renal/urinary system MP:0005367 9.1 CDC73 HNF1A KRT7 MITF PBRM1 VHL

Drugs & Therapeutics for Clear Cell Papillary Renal Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Clear Cell Papillary Renal Cell Carcinoma

Genetic Tests for Clear Cell Papillary Renal Cell Carcinoma

Anatomical Context for Clear Cell Papillary Renal Cell Carcinoma

MalaCards organs/tissues related to Clear Cell Papillary Renal Cell Carcinoma:

40
Kidney, Breast, Cortex, Uterus

Publications for Clear Cell Papillary Renal Cell Carcinoma

Articles related to Clear Cell Papillary Renal Cell Carcinoma:

(show top 50) (show all 95)
# Title Authors PMID Year
1
Advances in the Characterization of Clear Cell Papillary Renal Cell Carcinoma: Identifying the Sheep in Wolf's Clothing. 61
33579573 2021
2
The Clinicopathologic and Molecular Landscape of Clear Cell Papillary Renal Cell Carcinoma: Implications in Diagnosis and Management. 61
33046271 2021
3
Clear cell papillary renal cell carcinoma: Characteristics and survival outcomes from a large single institutional series. 61
33771410 2021
4
Cytomorphologic analysis of clear cell papillary renal cell carcinoma: Distinguishing diagnostic features. 61
33036062 2021
5
Should cytologists diagnose clear cell papillary renal cell carcinoma on cytologic material? 61
33036064 2021
6
Carbonic anhydrase IX: a regulator of pH and participant in carcinogenesis. 61
33619217 2021
7
Clear cell papillary renal cell carcinoma: an update after 15 years. 61
33223139 2021
8
Defining clear cell papillary renal cell carcinoma in routine clinical practice. 61
31989679 2020
9
Clear Cell Papillary Renal Cell Carcinoma: A Recent Entity With Distinct Imaging Patterns. 61
31770020 2020
10
Computed tomography imaging characteristics of clear cell papillary renal cell carcinoma. 61
31851455 2020
11
A Case of Clear Cell Papillary Renal Cell Carcinoma With Prominent Glycogen-Containing Intranuclear Inclusions. 61
30813834 2019
12
Clear cell papillary renal cell carcinoma: molecular profile and virtual karyotype. 61
31175917 2019
13
Clear Cell Papillary Renal Cell Carcinoma. 61
30672334 2019
14
Genetic Underpinnings of Renal Cell Carcinoma With Leiomyomatous Stroma. 61
30986793 2019
15
Renal cell carcinomas with a mesenchymal stromal component: what do we know so far? 61
31266596 2019
16
Clinical and morphologic review of 60 hereditary renal tumors from 30 hereditary renal cell carcinoma syndrome patients: lessons from a contemporary single institution series. 61
31332543 2019
17
Clear cell papillary renal cell carcinoma in a transplant kidney. 61
31180312 2019
18
Clear cell papillary renal cell carcinoma: a case report and literature review. 61
31249659 2019
19
Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma. 61
30924768 2019
20
Peritumoral pseudocapsule status according to pathological characteristics from robot-assisted laparoscopic partial nephrectomy for localized renal cell carcinoma. 61
30650470 2019
21
Clear cell papillary renal cell carcinoma: A case report and review of the literature. 61
30596034 2018
22
Clear cell papillary renal cell carcinoma - An indolent subtype of renal tumor. 61
30037497 2018
23
Expression of vitamin D receptor in clear cell papillary renal cell carcinoma. 61
29966830 2018
24
Renal tumors in end-stage renal disease: A comprehensive review. 61
30066367 2018
25
Clinical features and survival analysis of clear cell papillary renal cell carcinoma: A 10-year retrospective study from two institutions. 61
29963177 2018
26
The Tumor Entity Denominated "clear cell-papillary renal cell carcinoma" According to the WHO 2016 new Classification, have the Clinical Characters of a Renal Cell Adenoma as does Harbor a Benign Outcome. 61
28695322 2018
27
Renal cell carcinoma with angioleiomyoma-like stroma and clear cell papillary renal cell carcinoma: exploring SDHB protein immunohistochemistry and the relationship to tuberous sclerosis complex. 61
29180251 2018
28
Renal cell tumors with clear cell histology and intact VHL and chromosome 3p: a histological review of tumors from the Cancer Genome Atlas database. 61
28731045 2017
29
Genitourinary Malignancies in Transplant or Dialysis Patients: The Frequency of Two Newly Described 2016 World Health Organization Histopathologic Types. 61
28923625 2017
30
GATA3 as a valuable marker to distinguish clear cell papillary renal cell carcinomas from morphologic mimics. 61
28705707 2017
31
A contemporary series of renal masses with emphasis on recently recognized entities and tumors of low malignant potential: A report based on 624 consecutive tumors from a single tertiary center. 61
28554741 2017
32
Do clear cell papillary renal cell carcinomas have malignant potential? Diolombi ML, Cheng L, Argani P, Epstein JI.Am J Surg Pathol. December 2015;39(12):1621-1634. 61
28416105 2017
33
Clear Cell Papillary Renal Cell Carcinoma: New Clinical and Imaging Characteristics. 61
28130179 2017
34
MiR-1202 functions as a tumor suppressor in glioma cells by targeting Rab1A. 61
28443461 2017
35
Primary Renal Carcinoid with Bilateral Multiple Clear Cell Papillary Renal Cell Carcinomas. 61
28620558 2017
36
Cytomorphology of clear cell papillary renal cell carcinoma. 61
27636377 2017
37
Validation of 34betaE12 immunoexpression in clear cell papillary renal cell carcinoma as a sensitive biomarker. 61
27923499 2017
38
Reply to Williamson S.R. What is the malignant potential of clear cell papillary renal cell carcinoma? Urol Oncol 2016; 34: 420. 61
27697387 2016
39
What is the malignant potential of clear cell papillary renal cell carcinoma? 61
27364705 2016
40
Cytopathologic features of clear cell papillary renal cell carcinoma: A recently described variant to be considered in the differential diagnosis of clear cell renal epithelial neoplasms. 61
27062008 2016
41
Clear cell renal cell tumors: Not all that is "clear" is cancer. 61
26988177 2016
42
Multiple and bilateral kidney tumors with clear cells of three different histotypes: A case report with clinicopathologic and molecular study. 61
27061669 2016
43
Genetic mutations in accordance with a low malignant potential tumour are not demonstrated in clear cell papillary renal cell carcinoma. 61
26941183 2016
44
Incidence of Clear Cell Papillary Renal Cell Carcinoma in Low-Grade Renal Cell Carcinoma Cases: A 12-Year Retrospective Clinicopathologic Study From a Single Cancer Center. 61
26510859 2016
45
Clear cell papillary renal cell carcinoma, renal angiomyoadenomatous tumor, and renal cell carcinoma with leiomyomatous stroma relationship of 3 types of renal tumors: a review. 61
26897641 2016
46
Cystic clear cell papillary renal cell carcinoma: is it related to multilocular clear cell cystic neoplasm of low malignant potential? 61
26256827 2016
47
Clear cell papillary renal cell carcinoma as part of histologically discordant multifocal renal cell carcinoma: A case report and review of literature. 61
26857533 2016
48
Renal Neoplasms With Overlapping Features of Clear Cell Renal Cell Carcinoma and Clear Cell Papillary Renal Cell Carcinoma: A Clinicopathologic Study of 37 Cases From a Single Institution. 61
26752401 2016
49
Atypical Renal Cysts: A Morphologic, Immunohistochemical, and Molecular Study. 61
26574846 2016
50
Emerging Entities in Renal Neoplasia. 61
26612218 2015

Variations for Clear Cell Papillary Renal Cell Carcinoma

Expression for Clear Cell Papillary Renal Cell Carcinoma

Search GEO for disease gene expression data for Clear Cell Papillary Renal Cell Carcinoma.

Pathways for Clear Cell Papillary Renal Cell Carcinoma

Pathways related to Clear Cell Papillary Renal Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.29 HNF1A CA9 AMACR

GO Terms for Clear Cell Papillary Renal Cell Carcinoma

Biological processes related to Clear Cell Papillary Renal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.46 VHL TFE3 MITF HNF1A
2 placenta development GO:0001890 9.26 MME HNF1A
3 bile acid biosynthetic process GO:0006699 8.96 HNF1A AMACR
4 regulation of osteoclast differentiation GO:0045670 8.62 TFE3 MITF

Molecular functions related to Clear Cell Papillary Renal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein dimerization activity GO:0046983 8.8 TFE3 MITF HNF1A

Sources for Clear Cell Papillary Renal Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....