MCID: CLR017
MIFTS: 50

Clear Cell Sarcoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Clear Cell Sarcoma

MalaCards integrated aliases for Clear Cell Sarcoma:

Name: Clear Cell Sarcoma 12 15
Sarcoma, Clear Cell 44 73
Adult Soft Part Clear Cell Sarcoma 12
Malignant Melanoma of Soft Tissues 12
Melanoma, Malignant, of Soft Parts 12
Clear Cell Sarcoma of Soft Parts 12
Malignant Melanoma of Soft Parts 12
Sarcoma Clear Cell 55

Classifications:



External Ids:

Disease Ontology 12 DOID:4233
MeSH 44 D018227
NCIt 50 C27370 C3745

Summaries for Clear Cell Sarcoma

Disease Ontology : 12 A sarcoma that is characterized by solid nests and fascicles of tumor cells with clear cytoplasm and prominent nucleoli. It presents as a slow growing mass that especially affects tendons and aponeuroses and it is deeply situated.

MalaCards based summary : Clear Cell Sarcoma, also known as sarcoma, clear cell, is related to kidney clear cell sarcoma and melanoma of soft tissue. An important gene associated with Clear Cell Sarcoma is ATF1 (Activating Transcription Factor 1), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Tyrosine Kinases / Adaptors. The drugs Etoposide and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and lung, and related phenotypes are cellular and embryo

Wikipedia : 76 Clear-cell sarcoma (formerly known as malignant melanoma of the soft parts) is a rare form of cancer... more...

Related Diseases for Clear Cell Sarcoma

Diseases in the Small Cell Sarcoma family:

Clear Cell Sarcoma

Diseases related to Clear Cell Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 144)
# Related Disease Score Top Affiliating Genes
1 kidney clear cell sarcoma 34.1 BCOR WT1 YWHAE
2 melanoma of soft tissue 33.3 ATF1 CREB1 EWSR1
3 malignant spindle cell melanoma 30.4 KIT MITF
4 sarcomatosis 30.3 ATF1 EWSR1 WT1
5 neurofibroma 30.0 KIT MITF S100B
6 myxoid liposarcoma 30.0 ATF1 EWSR1 FUS
7 small intestinal sarcoma 30.0 IGF2 KIT
8 congenital mesoblastic nephroma 29.1 IGF2 KIT WT1
9 ewing sarcoma 25.6 ATF1 BCOR ENO2 EWSR1 FUS IGF2
10 sarcoma 11.1
11 wilms tumor 1 11.0
12 conventional central osteosarcoma 10.8 BCOR EWSR1
13 bone osteosarcoma 10.8 BCOR EWSR1
14 lentigo maligna melanoma 10.8 MITF S100B
15 intracranial cysts 10.8 ENO2 S100B
16 orbital cancer 10.8 ENO2 EWSR1
17 bednar tumor 10.7 ENO2 S100B
18 askin's tumor 10.7 ENO2 EWSR1
19 epithelioid malignant peripheral nerve sheath tumor 10.7 ENO2 S100B
20 middle cerebral artery infarction 10.7 ENO2 S100B
21 ossifying fibromyxoid tumor 10.7 ENO2 S100B
22 head injury 10.7 ENO2 S100B
23 myxoid leiomyosarcoma 10.7 BCOR YWHAE
24 reticular perineurioma 10.7 KIT S100B
25 melanotic neuroectodermal tumor 10.7 ENO2 S100B
26 pineocytoma 10.7 ENO2 S100B
27 mixed type thymoma 10.6 KIT S100B
28 melanoma 10.6
29 aggressive digital papillary adenocarcinoma 10.6 KIT S100B
30 papillary ependymoma 10.6 ENO2 S100B
31 respiratory system benign neoplasm 10.6 ENO2 MITF
32 breast angiosarcoma 10.6 KIT MITF
33 endometrial stromal nodule 10.6 BCOR YWHAE
34 amelanotic melanoma 10.6 KIT S100B
35 vulvar melanoma 10.6 ATF1 KIT
36 subependymal giant cell astrocytoma 10.5 ENO2 S100B
37 plexiform schwannoma 10.5 ENO2 KIT
38 conventional fibrosarcoma 10.5 ENO2 KIT
39 endometrial small cell carcinoma 10.5 ENO2 KIT
40 rete testis adenocarcinoma 10.5 ENO2 KIT
41 perineurioma 10.5 KIT S100B
42 myxofibrosarcoma 10.5 FUS S100B
43 mesenchymal cell neoplasm 10.5 EWSR1 KIT
44 angiomyoma 10.5 ENO2 KIT
45 juxtacortical chondroma 10.5 EWSR1 FUS
46 ewing's family of tumors 10.5 EWSR1 KIT
47 olfactory neuroblastoma 10.5 ENO2 EWSR1 S100B
48 small cell osteogenic sarcoma 10.5 BCOR ENO2 EWSR1
49 granular cell tumor 10.5 ENO2 S100B
50 extraosseous ewing's sarcoma 10.5 ENO2 EWSR1 S100B

Graphical network of the top 20 diseases related to Clear Cell Sarcoma:



Diseases related to Clear Cell Sarcoma

Symptoms & Phenotypes for Clear Cell Sarcoma

MGI Mouse Phenotypes related to Clear Cell Sarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.97 IGF2 KIT MITF BCOR WT1 CREB1
2 embryo MP:0005380 9.8 IGF2 KIT MITF BCOR WT1 CREB1
3 muscle MP:0005369 9.63 IGF2 KIT WT1 YWHAE CREB1 ERBB3
4 nervous system MP:0003631 9.56 IGF2 KIT MITF BCOR YWHAE CREB1
5 respiratory system MP:0005388 9.1 IGF2 KIT WT1 CREB1 ENO2 ERBB3

Drugs & Therapeutics for Clear Cell Sarcoma

Drugs for Clear Cell Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 114)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etoposide Approved Phase 3,Phase 2,Phase 1 33419-42-0 36462
2
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
3
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
4
Vincristine Approved, Investigational Phase 3,Phase 2 2068-78-2, 57-22-7 5978
5
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
6
Dactinomycin Approved, Investigational Phase 3,Phase 2 50-76-0 2019 457193
7
Lenograstim Approved, Investigational Phase 3,Phase 2,Phase 1 135968-09-1
8
Sulfamethoxazole Approved Phase 3 723-46-6 5329
9
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1 51-75-2 4033
10
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
11
Trimethoprim Approved, Vet_approved Phase 3 738-70-5 5578
12
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
13
Cyproheptadine Approved Phase 3 129-03-3 2913
14
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
15
Doxil Approved June 1999 Phase 3,Phase 2 31703
16 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
17 Alkylating Agents Phase 3,Phase 2,Phase 1
18 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
19 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
20 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
21 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
22 Etoposide phosphate Phase 3,Phase 2,Phase 1
23 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
24 Anti-Infective Agents Phase 3,Phase 2,Phase 1
25 Antirheumatic Agents Phase 3,Phase 2,Phase 1
26 Antimitotic Agents Phase 3,Phase 2,Phase 1,Not Applicable
27 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
28 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1,Not Applicable
29
Isophosphamide mustard Phase 3,Phase 2,Phase 1 0
30 Analgesics Phase 3
31 Central Nervous System Depressants Phase 3
32 Adjuvants, Anesthesia Phase 3
33 Adjuvants, Immunologic Phase 3,Phase 2,Phase 1
34 Narcotics Phase 3
35 Analgesics, Opioid Phase 3
36 Anesthetics Phase 3
37 Anesthetics, General Phase 3
38 Anesthetics, Intravenous Phase 3
39 Peripheral Nervous System Agents Phase 3
40 Liver Extracts Phase 3,Phase 1,Phase 2,Not Applicable
41
Histamine Phosphate Phase 3 51-74-1 65513
42 Serotonin Agents Phase 3
43 Serotonin Antagonists Phase 3
44 Gastrointestinal Agents Phase 3
45 Neurotransmitter Agents Phase 3
46 Histamine Antagonists Phase 3
47 Histamine H1 Antagonists Phase 3
48 Dermatologic Agents Phase 3
49 Anti-Allergic Agents Phase 3
50 Antipruritics Phase 3

Interventional clinical trials:

(show all 36)
# Name Status NCT ID Phase Drugs
1 Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors Completed NCT00002610 Phase 3 carboplatin;cyclophosphamide;doxorubicin hydrochloride;etoposide;vincristine sulfate
2 Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer Completed NCT00002611 Phase 3 cyclophosphamide;doxorubicin hydrochloride;etoposide;vincristine sulfate
3 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
4 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3 doxorubicin hydrochloride;ifosfamide
5 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3 doxorubicin hydrochloride;ifosfamide;isolated perfusion
6 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3 Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
7 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
8 Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney Unknown status NCT00025103 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;etoposide;melphalan;vincristine sulfate
9 Phase 2 Study in Patients With MiT Tumors Completed NCT00557609 Phase 2 ARQ 197
10 A Study of R1507 in Participants With Recurrent or Refractory Sarcoma Completed NCT00642941 Phase 2 RG1507
11 Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors Completed NCT00335556 Phase 2 Doxorubicin Hydrochloride;Irinotecan Hydrochloride;Cyclophosphamide;Etoposide;Carboplatin;Vincristine Sulfate
12 Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery Completed NCT01553539 Phase 2 therapeutic angiotensin-(1-7)
13 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
14 Second Line ColoRectal Cancer Therapy in Combination With Combination of FOL- Folinic Acid(Leucovorin), F - Fluorouracil and OX - Oxaliplatin (FOLFOX) Completed NCT00278889 Phase 2 AZD2171;5-fluorouracil;Leucovorin;Oxaliplatin;Bevacizumab
15 Chemotherapy in Treating Patients With Solid Tumors Completed NCT00003103 Phase 1, Phase 2 docetaxel
16 High-dose ICE With Amifostine Completed NCT00003657 Phase 2 Amifostine;Carboplatin;Etoposide;Ifosfamide
17 QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma Recruiting NCT03132155 Phase 2 AMG 337
18 Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors Recruiting NCT02867592 Phase 2 Cabozantinib S-malate
19 Induction Therapy With Vemurafenib and Cobimetinib to Optimize Nivolumab and Ipilimumab Therapy Recruiting NCT02968303 Phase 2 Vemurafenib and Cobimetinib
20 CREATE: Cross-tumoral Phase 2 With Crizotinib Active, not recruiting NCT01524926 Phase 2 Crizotinib (PF-02341066)
21 Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By Surgery Active, not recruiting NCT01164228 Phase 2 gemcitabine hydrochloride;sunitinib malate
22 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
23 Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery Completed NCT01061411 Phase 1 Dalteparin;Sunitinib Malate
24 Thalidomide and Docetaxel in Treating Patients With Advanced Cancer Completed NCT00049296 Phase 1 docetaxel;thalidomide
25 Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors Recruiting NCT02390843 Phase 1 Simvastatin;Cyclophosphamide;Topotecan;Myeloid growth factor
26 Vaccine Trial for Clear Cell Sarcoma, Pediatric Renal Cell Carcinoma, Alveolar Soft Part Sarcoma and Children With Stage IV Melanoma Active, not recruiting NCT00258687 Phase 1
27 Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors Active, not recruiting NCT01331135 Phase 1 sirolimus
28 Study of Information Received About Fertility and Infertility in Patients Who Have Finished Treatment for Cancer Unknown status NCT01295463
29 Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom Unknown status NCT00757614
30 Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor Completed NCT01118078
31 E-MOSAIC Electronic Tool to Monitor Symptoms Completed NCT00477919
32 Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients Completed NCT00253383 Not Applicable
33 Molecular-Guided Therapy for Childhood Cancer Recruiting NCT02162732 Not Applicable
34 Study of Kidney Tumors in Younger Patients Recruiting NCT00898365
35 Studying Biomarkers in Samples From Younger Patients With Kidney Cancer Withdrawn NCT01642095
36 Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors Withdrawn NCT00499291 Not Applicable paclitaxel albumin-stabilized nanoparticle formulation

Search NIH Clinical Center for Clear Cell Sarcoma

Cochrane evidence based reviews: sarcoma, clear cell

Genetic Tests for Clear Cell Sarcoma

Anatomical Context for Clear Cell Sarcoma

MalaCards organs/tissues related to Clear Cell Sarcoma:

41
Kidney, Bone, Lung, Liver, Lymph Node, Myeloid, Tongue

Publications for Clear Cell Sarcoma

Articles related to Clear Cell Sarcoma:

(show top 50) (show all 473)
# Title Authors Year
1
Clear cell sarcoma arising from paraspinal ligament of thoracic spine: Report of an unusual case. ( 29676368 )
2018
2
Clear Cell Sarcoma-like Tumor of the Gastrointestinal Tract: Clinical Outcome and Pathologic Features of a Molecularly Characterized Tertiary Center Case Series. ( 29491075 )
2018
3
Corrigendum: Zekri W, Alfaar AS, Yehia D, etA al. Clear cell sarcoma of the kidney: Patients' characteristics and improved outcome in developing countries. Pediatr Blood Cancer. 2014;61:2185-2190. DOI: 10.1002/pbc.25192. ( 29575451 )
2018
4
The epidemiology and survivorship of clear cell sarcoma: a National Cancer Database (NCDB) review. ( 29961184 )
2018
5
Delayed Metastasis of Clear Cell Sarcoma of Kidney to Bladder After 7 Disease-Free Years. ( 29509095 )
2018
6
Diffuse Strong BCOR Immunoreactivity Is a Sensitive and Specific Marker for Clear Cell Sarcoma of the Kidney (CCSK) in Pediatric Renal Neoplasia. ( 29851702 )
2018
7
Clear Cell Sarcoma of the Tongue on MRI and PET/CT. ( 29401145 )
2018
8
Dysregulated mitogen-activated protein kinase signalling as an oncogenic basis for clear cell sarcoma of the kidney. ( 29243812 )
2018
9
Clear Cell Sarcoma: A Case Report and Review of Literature. ( 29951180 )
2018
10
Clear Cell Sarcoma-Like Tumor of the Gastrointestinal Tract. ( 29623567 )
2018
11
Renal clear cell sarcoma presenting as a spontaneous renal hematoma: A rare presentation. ( 29607435 )
2018
12
Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 'CREATE'. ( 29741569 )
2018
13
Establishment and proteomic characterization of patient-derived clear cell sarcoma xenografts and cell lines. ( 29197033 )
2018
14
Cutaneous Melanocytoma With CRTC1-TRIM11 Fusion: Report of 5 Cases Resembling Clear Cell Sarcoma. ( 29240581 )
2018
15
Clear cell sarcoma of the gastrointestinal tract and malignant gastrointestinal neuroectodermal tumour: distinct or related entities? A review. ( 29970252 )
2018
16
Therapeutic potential of CPI-613 for targeting tumorous mitochondrial energy metabolism and inhibiting autophagy in clear cell sarcoma. ( 29879220 )
2018
17
FNAC aided diagnosis of clear cell sarcoma of kidney: Report of two cases in infants. ( 28421721 )
2017
18
Clear cell sarcoma of the scalp: A case report. ( 28791725 )
2017
19
Complete response of mediastinal clear cell sarcoma to pembrolizumab with radiotherapy. ( 28725344 )
2017
20
Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma. ( 28745431 )
2017
21
Subcutaneous pigmented clear cell sarcoma as a challenging simulator of melanoma. ( 28815555 )
2017
22
Imprint cytology of clear cell sarcoma-like tumor of the gastrointestinal tract in the small intestine: A case report. ( 28695686 )
2017
23
Malignant melanocytic neoplasm of pancreas with liver metastasis: Is it malignant melanoma or clear cell sarcoma? ( 28195103 )
2017
24
Clear cell sarcoma of kidney involving a horseshoe kidney and harboring EGFR internal tandem duplication. ( 28440018 )
2017
25
Primary Clear Cell Sarcoma of the Dermis Mimicking Malignant Melanoma. ( 29072181 )
2017
26
Clear cell sarcoma-like tumor of the gastrointestinal tract: A clinicopathological review. ( 28887884 )
2017
27
Percutaneous radiofrequency ablation for a recurrent metastasis after resection of liver metastases from an ileal clear-cell sarcoma: Long-term local tumor control. ( 29484066 )
2017
28
Renal Clear Cell Sarcoma - Anaplastic Variant: A Rare Entity. ( 28273978 )
2017
29
Brain metastasis from gastrointestinal clear cell sarcoma. ( 27719746 )
2017
30
Concurrent occurrence of neuroblastoma and clear cell sarcoma of kidney in an infant: Is it a random event? ( 28195107 )
2017
31
Primary mediastinal clear cell sarcoma: a case report and review of the literature. ( 28086809 )
2017
32
A case of clear cell sarcoma-A rare malignancy. ( 28587971 )
2017
33
Diagnostic utility of cyclin D1 in the diagnosis of small round blue cell tumors in children and adolescents: beware of cyclin D1 expression in clear cell sarcoma of the kidney and CIC-DUX4 fusion-positive sarcomas. Comment on Magro et al (2016). ( 28499544 )
2017
34
Primary Renal Sarcomas With BCOR-CCNB3 Gene Fusion: A Report of 2 Cases Showing Histologic Overlap With Clear Cell Sarcoma of Kidney, Suggesting Further Link Between BCOR-related Sarcomas of the Kidney and Soft Tissues. ( 28817404 )
2017
35
Bladder Recurrence of Clear Cell Sarcoma of the Kidney Seven Years After Initial Presentation. ( 28438624 )
2017
36
Clear cell sarcoma with intraepidermal nests requiring the differential diagnosis of malignant melanoma. ( 28256744 )
2017
37
Dual tumor - Clear cell sarcoma of kidney with differentiating neuroblastoma: A rare case with review of literature. ( 28195106 )
2017
38
Diagnostic utility of cyclin D1 in the diagnosis of small round blue cell tumors in children and adolescents: beware of cyclin D1 expression in clear cell sarcoma of the kidney and CIC-DUX4 fusion-positive sarcomas. Comment on Magro et al (2016)-reply. ( 28499546 )
2017
39
Activity and safety of crizotinib in patients with advanced clear cell sarcoma with MET alterations. European Organization for Research and Treatment of Cancer phase 2 trial 90101 "CREATE". ( 28950372 )
2017
40
Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of Infancy: Overlapping Genetic Features With Clear Cell Sarcoma of Kidney. ( 26945340 )
2016
41
Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression. ( 26848979 )
2016
42
Biology and management of clear cell sarcoma: state of the art and future perspectives. ( 27253849 )
2016
43
Revealing the role of VEGFA in clear cell sarcoma of the kidney by protein-protein interaction network and significant pathway analysis. ( 26893674 )
2016
44
Gastrointestinal clear cell sarcoma-like tumour of the ascending colon. ( 26890846 )
2016
45
A giant clear cell sarcoma on right scapular: A case report. ( 27452744 )
2016
46
Clear cell sarcoma of vulva. A case report. ( 27869448 )
2016
47
Clear cell sarcoma of the paraspinal ligament - A rare tumor at an unusual location: A review. ( 27381137 )
2016
48
Mutually exclusive BCOR internal tandem duplications and YWHAE-NUTM2 fusions in clear cell sarcoma of kidney: not the full story. ( 27000436 )
2016
49
Primary pulmonary clear cell sarcoma-the first two reported cases. ( 27112339 )
2016
50
Intraperitoneal Rosai-Dorfman disease associated with clear cell sarcoma: first case report. ( 27814905 )
2016

Variations for Clear Cell Sarcoma

Expression for Clear Cell Sarcoma

Search GEO for disease gene expression data for Clear Cell Sarcoma.

Pathways for Clear Cell Sarcoma

GO Terms for Clear Cell Sarcoma

Biological processes related to Clear Cell Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.86 ATF1 BCOR CREB1 EWSR1 FUS IGF2
2 positive regulation of protein kinase B signaling GO:0051897 9.58 ERBB3 IGF2 KIT
3 negative regulation of apoptotic process GO:0043066 9.55 ERBB3 IGF2 KIT MITF WT1
4 positive regulation of MAPK cascade GO:0043410 9.54 ERBB3 IGF2 KIT
5 melanocyte differentiation GO:0030318 9.32 KIT MITF
6 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.13 ERBB3 IGF2 KIT
7 positive regulation of cardiac muscle tissue development GO:0055025 8.62 CREB1 ERBB3

Molecular functions related to Clear Cell Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription coregulator activity GO:0003712 9.33 CREB1 EWSR1 FUS
2 obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.32 ERBB3 KIT
3 identical protein binding GO:0042802 9.17 ATF1 CREB1 ERBB3 EWSR1 FUS S100B
4 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705 9.13 ATF1 CREB1 MITF
5 protein binding GO:0005515 10.07 ATF1 BCOR CREB1 ENO2 ERBB3 EWSR1

Sources for Clear Cell Sarcoma

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34 ICD10 via Orphanet
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45 MESH via Orphanet
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64 QIAGEN
69 SNOMED-CT via HPO
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