Cleft Lip/palate disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

FLP MCID: CLF004 MIFTS: 55	Cleft Lip/palate (FLP) Categories: Fetal diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Cleft Lip/palate

MalaCards integrated aliases for Cleft Lip/palate:

Name: Cleft Lip/palate ⁵⁹ ²⁹

Cleft Lip and Palate ⁵⁹ ⁴³

Cleft Lip-Alveolus-Palate Syndrome ⁵⁹

Alveolar Cleft Lip and Palate ⁵⁹

Flp ⁵⁹

Classifications:

MalaCards categories:
Global: Fetal diseases Rare diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Congenital malformations, deformations and chromosomal abnormalities

Cleft lip and cleft palate

Cleft palate with cleft lip

Cleft hard and soft palate with bilateral cleft lip

Cleft hard and soft palate with unilateral cleft lip

Cleft hard palate with bilateral cleft lip

Cleft hard palate with unilateral cleft lip

Cleft soft palate with bilateral cleft lip

Cleft soft palate with unilateral cleft lip

Unspecified cleft palate with bilateral cleft lip

Unspecified cleft palate with unilateral cleft lip

Orphanet: ⁵⁹

Developmental anomalies during embryogenesis

External Ids:

Orphanet ⁵⁹ ORPHA199306

ICD10 via Orphanet ³⁴ Q37.0 Q37.4 Q37.5 more

UMLS via Orphanet ⁷⁴ C0158646

Sources

Summaries for Cleft Lip/palate

MedlinePlus : ⁴³ Cleft lip and cleft palate are birth defects that occur when a baby's lip or mouth do not form properly. They happen early during pregnancy. A baby can have a cleft lip, a cleft palate, or both. A cleft lip happens if the tissue that makes up the lip does not join completely before birth. This causes an opening in the upper lip. The opening can be a small slit or a large opening that goes through the lip into the nose. It can be on one or both sides of the lip or, rarely, in the middle of the lip. Children with a cleft lip also can have a cleft palate. The roof of the mouth is called the "palate." With a cleft palate, the tissue that makes up the roof of the mouth does not join correctly. Babies may have both the front and back parts of the palate open, or they may have only one part open. Children with a cleft lip or a cleft palate often have problems with feeding and talking. They also might have ear infections, hearing loss, and problems with their teeth. Often, surgery can close the lip and palate. Cleft lip surgery is usually done before age 12 months, and cleft palate surgery is done before 18 months. Many children have other complications. They may need additional surgeries, dental and orthodontic care, and speech therapy as they get older. With treatment, most children with clefts do well and lead a healthy life. Centers for Disease Control and Prevention

MalaCards based summary : Cleft Lip/palate, also known as cleft lip and palate, is related to ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 1 and short-rib thoracic dysplasia 7 with or without polydactyly. An important gene associated with Cleft Lip/palate is DLX4 (Distal-Less Homeobox 4), and among its related pathways/superpathways are Mesodermal Commitment Pathway and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Coagulants and Fibrin Tissue Adhesive have been mentioned in the context of this disorder. Affiliated tissues include bone, heart and skin, and related phenotypes are embryo and cellular

Sources

Related Diseases for Cleft Lip/palate

Diseases related to Cleft Lip/palate via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 281)

#	Related Disease	Score	Top Affiliating Genes
1	ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 1	34.6	EEC1 TP63
2	short-rib thoracic dysplasia 7 with or without polydactyly	32.5	INTU WDR35
3	short-rib thoracic dysplasia 3 with or without polydactyly	32.3	NEK1 WDR19 WDR35 WDR60
4	short-rib thoracic dysplasia 12	32.1	NEK1 WDR19
5	bartsocas-papas syndrome	32.0	IRF6 TP63
6	short-rib thoracic dysplasia 1 with or without polydactyly	31.8	WDR19 WDR35 WDR60
7	cleft lip	31.0	ARHGAP29 BMP4 CDH1 DLX4 FGFR1 IRF6
8	cleft lip and alveolus	30.9	IRF6 MSX1 NECTIN1 TP63
9	isolated cleft lip	30.7	IRF6 MSX1 NECTIN1 TP63
10	tooth size	30.5	BMP4 MSX1
11	tooth agenesis	29.9	BMP4 CDH1 FGFR1 IRF6 MSX1
12	cleft palate, isolated	29.9	ARHGAP29 BMP4 FGFR1 IRF6 MSX1 NECTIN1
13	ankyloblepharon-ectodermal defects-cleft lip/palate	12.9
14	cleft lip/palate-ectodermal dysplasia syndrome	12.9
15	arthrogryposis, ectodermal dysplasia, cleft lip/palate, and developmental delay	12.8
16	ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3	12.8
17	coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or mental retardation	12.7
18	microcephaly, corpus callosum dysgenesis, and cleft lip/palate	12.6
19	tibial hemimelia cleft lip palate	12.5
20	cleft lip/palate with abnormal thumbs and microcephaly	12.5
21	ectrodactyly and ectodermal dysplasia without cleft lip/palate	12.4
22	cleft lip/palate with characteristic facies, intestinal malrotation, and lethal congenital heart disease	12.4
23	radius, aplasia of, with cleft lip/palate	12.4
24	hypotrichosis, progressive patterned scalp, with wiry hair, onycholysis, and cleft lip/palate	12.4
25	cleft lip palate dysmorphism kumar type	12.4
26	cleft lip palate oligodontia syndactyly pili torti	12.4
27	cleft lip palate pituitary deficiency	12.4
28	cleft lip palate-tetraphocomelia	12.4
29	craniosynostosis cleft lip palate arthrogryposis	12.4
30	holoprosencephaly ectrodactyly cleft lip palate	12.4
31	lagophthalmia cleft lip palate	12.4
32	syndactyly ectodermal dysplasia cleft lip palate hand foot	12.4
33	cleft lip/palate-deafness-sacral lipoma syndrome	12.4
34	cleft lip and palate malrotation cardiopathy	12.3
35	cleft lip and palate-craniofacial dysmorphism-congenital heart defect-hearing loss syndrome	12.3
36	popliteal pterygium syndrome	12.2
37	rapp-hodgkin syndrome	12.2
38	hartsfield syndrome	12.2
39	blepharocheilodontic syndrome 1	12.1
40	vici syndrome	12.1
41	richieri-costa/guion-almeida syndrome	12.1
42	acrofrontofacionasal dysostosis	12.0
43	cleft palate, cardiac defects, and mental retardation	12.0
44	zlotogora syndrome	12.0
45	uveal coloboma-cleft lip and palate-intellectual disability	11.8
46	pilotto syndrome	11.8
47	orofaciodigital syndrome vi	11.8
48	martinez monasterio pinheiro syndrome	11.7
49	samson viljoen syndrome	11.6
50	kapur-toriello syndrome	11.6

Graphical network of the top 20 diseases related to Cleft Lip/palate:

Sources

Symptoms & Phenotypes for Cleft Lip/palate

MGI Mouse Phenotypes related to Cleft Lip/palate:

⁴⁶ (show all 15)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	embryo	MP:0005380	10.37	ARHGAP29 BMP4 CDH1 DLG1 FGFR1 INTU
2	cellular	MP:0005384	10.35	BMP4 CDH1 DLG1 FGFR1 INTU IRF6
3	growth/size/body region	MP:0005378	10.35	ARHGAP29 BMP4 CDH1 DLG1 FGFR1 INTU
4	craniofacial	MP:0005382	10.3	ARHGAP29 BMP4 DLG1 FGFR1 IRF6 MEIS2
5	mortality/aging	MP:0010768	10.3	ARHGAP29 BMP4 CDH1 DLG1 FGFR1 INTU
6	digestive/alimentary	MP:0005381	10.29	ARHGAP29 BMP4 CDH1 DLG1 FGFR1 IRF6
7	cardiovascular system	MP:0005385	10.2	BMP4 CDH1 FGFR1 INTU MEIS2 MSX1
8	limbs/digits/tail	MP:0005371	10.1	BMP4 DLG1 FGFR1 INTU IRF6 MSX1
9	integument	MP:0010771	10.09	BMP4 CDH1 FGFR1 IRF6 MSX1 NECTIN1
10	nervous system	MP:0003631	9.96	BMP4 DLG1 FGFR1 INTU MEIS2 MSX1
11	hearing/vestibular/ear	MP:0005377	9.93	BMP4 FGFR1 IRF6 MEIS2 MSX1 WDR19
12	muscle	MP:0005369	9.92	BMP4 DLG1 FGFR1 MSX1 TP63 WDR19
13	skeleton	MP:0005390	9.73	BMP4 DLG1 FGFR1 INTU IRF6 MEIS2
14	renal/urinary system	MP:0005367	9.7	BMP4 DLG1 FGFR1 INTU NEK1 TP63
15	vision/eye	MP:0005391	9.28	BMP4 DLG1 FGFR1 INTU MEIS2 MSX1

Sources

Drugs & Therapeutics for Cleft Lip/palate

Drugs for Cleft Lip/palate (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Coagulants

Phase 4

Fibrin Tissue Adhesive

Phase 4

Hemostatics

Phase 4

leucovorin

Approved

Phase 3

58-05-9

6006 143

Synonyms:

(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate

(6R,S)-5-Formyltetrahydrofolate

10-Formyl-7,8-dihydrofolate

10-Formyl-7,8-dihydrofolic acid

5 Formyltetrahydrofolate

5 Formyltetrahydropteroylglutamate

5-Formyl-5,6,7,8-tetrahydrofolate

5-Formyl-5,6,7,8-tetrahydrofolic acid

5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid

5-Formyltetrahydrofolate

5-formyltetrahydrofolic acid

5-Formyltetrahydrofolic acid

5-Formyltetrahydropteroylglutamate

5-Formyltetrahydropteroylglutamic acid

Acid, folinic

Acide folinique

Calcium citrovorum factor

Calcium folinate

Calcium leucovorin

Citrovorum factor

Factor, citrovorum

folinate

Folinate

Folinate, calcium

Folinic acid

Folinic acid calcium salt

Folinic acid calcium salt USP27

Folinic acid SF

Folinic acid-SF

L(-)-5-Formyl-5,6,7,8-tetrahydrofolate

L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid

Leucal

Leucovorin

Leucovorin calcium

Leucovorin folinic acid

Leucovorin, (D)-isomer

Leucovorin, (DL)-isomer

Leucovorin, (R)-isomer

Leucovorin, calcium

Leucovorin, calcium (1:1) salt

Leucovorin, calcium (1:1) salt, (DL)-isomer

Leucovorin, calcium (1:1) salt, pentahydrate

Leucovorin, monosodium salt

Leucovorinum

Leukovorin

Leukovorum

Levoleucovorin

L-leucovorin

L-Leucovorin

L-N-[P-[[(2-amino-5-Formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-glutamic acid

Monosodium salt leucovorin

N(5)-Formyltetrahydrofolate

N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid

N5-Formyl-5,6,7,8-tetrahydrofolate

N5-Formyl-5,6,7,8-tetrahydrofolic acid

N5-Formyltetrahydrofolate

N5-Formyltetrahydrofolic acid

Rescuvolin

Welcovorin

Wellcovorin

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 3

59-30-3

6037

Synonyms:

(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

01769_FLUKA

2d0k

33609-88-0

36653-55-1 (mono-potassium salt)

59-30-3

6484-89-5 (mono-hydrochloride salt)

AC-11682

AC1L1LNX

Acfol (Spain)

Acide folique

Acide folique [INN-French]

Acido folico

Acido folico [INN-Spanish]

Acidum folicum

Acidum folicum [INN-Latin]

Acifolic

AI3-26387

AKOS000503224

Antianemia factor

Apo-Folic

ARONIS014410

b9, Vitamin

BIDD:ER0563

BIDD:GT0641

BIF0608

bmse000299

BPBio1_000654

BSPBio_000594

BSPBio_002338

C00504

C20H20N6O6

CAS-59-30-3

CCRIS 666

CHEBI:27470

CHEMBL1622

CID6037

CPD000471860

Cytofol

D00070

DB00158

DivK1c_000494

Dosfolat b activ

Dosfolat B activ

EINECS 200-419-0

F0043

F7876_SIAL

F7876_SIGMA

F8758_SIGMA

F8798_SIAL

F8890_SIGMA

Facid

Factor U

FOL

Folacid

Folacin

Folaemin

Folaemin [Netherlands]

Folan

Folasic (Australia)

Folate

Folbal

Folcidin

Folcidin (VAN)

Folcysteine

Foldine

Foldine [France]

Folettes

Foliamin

Folic

folic acid

Folic acid (JP15/USP/INN)

Folic acid (TN)

Folic acid [BAN:INN:JAN]

Folic acid [INN:BAN:JAN]

Folic acid dihydrate

Folic acid, (D)-isomer

Folic acid, (DL)-isomer

Folic acid, calcium salt (1:1)

Folic acid, monopotassium salt

Folic acid, monosodium salt

Folic acid, potassium salt

Folic acid, sodium salt

Folicet

Folicet (TN)

Folico

Folico (Italy)

Folina

Folina (Italy)

Folipac

Folsaeure

Folsan

Folsaure

Folsäure

Folsav

Folvite

Folvron

Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L

HMS1921D20

HMS2092N17

HMS501I16

HSDB 2002

IDI1_000494

Incafolic

InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s

KBio1_000494

KBio2_001861

KBio2_004429

KBio2_006997

KBio3_001558

KBioGR_002222

KBioSS_001861

Kyselina listova

Kyselina listova [Czech]

Liver lactobacillus casei factor

Liver Lactobacillus casei factor

LS-2157

Millafol

Mission prenatal

Mittafol

MLS001304016

MLS001335861

MolPort-004-285-551

N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid

N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamate

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid

N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-Pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

NCGC00016265-01

NCGC00142391-01

nchembio.108-comp10

Nifolin

Nifolin [Denmark]

NINDS_000494

Novofolacid

Novofolacid [Canada]

N-Pteroyl-L-glutamate

N-pteroyl-L-glutamic acid

N-Pteroyl-L-glutamic acid

NSC 3073

PGA

PGA (VAN)

Prestwick_230

Prestwick3_000627

PteGlu

Pteroylglutamate

Pteroylglutamic acid

Pteroyl-L-glutamate

Pteroyl-L-glutamic acid

Pteroyl-L-monoglutamate

Pteroyl-L-monoglutamic acid

Pteroylmonoglutamate

Pteroylmonoglutamic acid

SAM002264616

SDCCGMLS-0066738.P001

Serum Folate Level

SMP2_000137

SMR000471860

SPBio_001357

Spectrum_001381

SPECTRUM1502020

Spectrum2_001459

Spectrum3_000749

Spectrum4_001751

Spectrum5_000602

UNII-935E97BOY8

Usaf cb-13

Vitamin B11

Vitamin b9

Vitamin B9

Vitamin Bc

Vitamin BC

Vitamin be

Vitamin Be

Vitamin m

Vitamin M

Vitamins

Phase 3

Vitamin B9

Phase 3

Vitamin B Complex

Phase 3

Micronutrients

Phase 3

Folate

Phase 3

Hematinics

Phase 3

Trace Elements

Phase 3

Bupivacaine

Approved, Investigational

Phase 2

2180-92-9, 38396-39-3

2474

Synonyms:

( inverted exclamation markA)-bupivacaine

(+-)-Bupivacaine

(±)-bupivacaine

(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide

(RS)-bupivacaine

15233-43-9

1-Butyl-2',6'-pipecoloxylidide

1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide

1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide

2180-92-9

38396-39-3

AB00053674

Abbott brand OF bupivacaine hydrochloride

AC1L1DRE

AC1Q5LX4

AC-2096

AH 250

AKOS001637202

Anekain

Anhydrous, bupivacaine

AR-1A0242

Astra brand OF bupivacaine hydrochloride

AstraZeneca brand OF bupivacaine hydrochloride

Aventis brand OF bupivacaine hydrochloride

Bio-0886

Bloqueina

BPBio1_000298

Braun brand OF bupivacaine hydrochloride

Braun, bupivacaina

BRD-A01636364-003-05-2

BSPBio_000270

BSPBio_002607

Bucaine

Bucaine (TN)

Bupivacain janapharm

Bupivacain RPR

Bupivacaina

Bupivacaina [INN-Spanish]

Bupivacaina braun

bupivacaine

Bupivacaine (INN)

Bupivacaine [INN:BAN]

Bupivacaine anhydrous

Bupivacaine carbonate

Bupivacaine Carbonate

Bupivacaine HCL

Bupivacaine HCL kit

Bupivacaine HCL KIT

Bupivacaine hydrochloride

Bupivacaine monohydrochloride, monohydrate

Bupivacaine Monohydrochloride, Monohydrate

Bupivacain-RPR

Bupivacainum

Bupivacainum [INN-Latin]

Bupivan

Buvacaina

C07529

C18H28N2O

Carbonate, bupivacaine

Carbostesin

cBupivacaine

CBupivacaine

CHEBI:3215

CHEMBL1098

CID2474

D07552

DB00297

DepoBupivacaine

DivK1c_000758

dl-1-Butyl-2',6'-pipecoloxylidide

DL-Bupivacaine

Dolanaest

DUR-843

EINECS 218-553-3

EINECS 253-911-2

HMS2090F12

Hydrochloride, bupivacaine

IDI1_000758

Inibsa brand OF bupivacaine hydrochloride

Janapharm, bupivacain

Jenapharm brand OF bupivacaine hydrochloride

KBio1_000758

KBio2_002004

KBio2_004572

KBio2_007140

KBio3_001827

KBioGR_001516

KBioSS_002004

KST-1A4609

L000695

LAC-43

LS-109841

LS-2222

Marcain

Marcaina

Marcaine

Marcaine HCL

Marcaine Spinal

MLS001361336

MolPort-004-955-820

NCGC00178579-01

NCGC00178579-02

NINDS_000758

NSC119660

Pisa brand OF bupivacaine hydrochloride

Prestwick0_000305

Prestwick1_000305

Prestwick2_000305

Prestwick3_000305

racemic bupivacaine

Sensorcaine

Sensorcaine-MPF

Sensorcaine-MPF Spinal

SMR000058218

SPBio_001558

SPBio_002489

Spectrum_001524

Spectrum2_001589

Spectrum3_000974

Spectrum4_001098

Spectrum5_001483

Strathmann brand OF bupivacaine hydrochloride

Svedocain sin vasoconstr

Transdur-Bupivacaine

UNII-Y8335394RO

Win 11318

Win 11318 HCl

Acetaminophen

Approved

Phase 2

103-90-2

1983

Synonyms:

4-(acetylamino)Phenol

4-(Acetylamino)phenol

4-acetamidophenol

4-Acetamidophenol

4-Acetaminophenol

4'-hydroxyacetanilide

4'-Hydroxyacetanilide

4-Hydroxyacetanilide

4-Hydroxyanilid kyseliny octove

A.F. anacin

Abenol

Abensanil

Abrol

Abrolet

AC1Q1KYJ

AC1Q1KYK

Acamol

Accu-tap

Accu-Tap

Acenol

Acephen

Acertol

Aceta elixir

Aceta Elixir

Aceta tablets

Aceta Tablets

Acetaco

Acetagesic

Acetalgin

Acetaminofen

Acetaminofén

Acetaminophen uniserts

Acetaminophene

Acétaminophène

Acetamol

Acetavance

Acetofen

Actamin

Actamin extra

Actamin super

Actifed plus

Actifed Plus

Actimol

Actimol chewable tablets

Actimol children's suspension

Actimol infants' suspension

Actimol junior strength caplets

Actron

Afebrin

Afebryl

Aferadol

Algesidal

Algina

Algomol

Algotropyl

Allay

alpha-Per

Alpiny

Alpinyl

Alvedon

Amadil

Aminofen

Aminofen max

Anacin

Anacin 3

Anacin-3

Anacin-3 extra strength

Anadin dla dzieci

Anaflon

Analter

Anapap

Andox

Anelix

Anexsia

Anexsia 10/660

Anexsia 5/325

Anexsia 7.5/325

Anexsia 7.5/650

Anhiba

Anoquan

Anti-algos

Antidol

Anuphen

Apacet

Apacet capsules

Apacet elixir

Apacet extra strength caplets

Apacet extra strength tablets

Apacet regular strength tablets

Apadon

Apamid

Apamide

APAP

a-Per

A-Per

Apitrelal

apo-Acetaminophen

Arfen

Arthralgen

Asetam

Asomal

Aspac

Aspirin free anacin maximum strength caplets

Aspirin free anacin maximum strength gel caplets

Aspirin free anacin maximum strength tablets

Aspirin-free anacin

Aspirin-free excedrin caplets

Asplin

Atasol

Atasol caplets

Atasol drops

Atasol forte caplets

Atasol forte tablets

Atasol oral solution

Atasol tablets

Atralidon

Babikan

Bacetamol

Bancap

Bancap HC

Banesin

Bayer Select

Bayer select allergy-sinus

Bayer select head cold

Bayer select headache pain

Bayer select maximum strength headache pain relief formula

Bayer select menstrual multi-symptom

Bayer select sinus pain relief

Benmyo

Ben-u-ron

Bickie-mol

Biocetamol

Bucet

Butalbital

Butapap

Cadafen

Calapol

Calmanticold

Calonal

Calpol

Capital

Capital with codeine

Captin

Causalon

CCRIS 3

Cefalex

Cetadol

CHEBI:46195

Children'S acetaminophen elixir drops

Children'S acetaminophen oral solution

Children'S tylenol chewable

Claradol codeine

Clixodyne

Codabrol

COD-Acamol forte

Codalgin

Codapane

Codicet

Codisal

Codisal forte

Codoliprane

Codral pain relief

Cofamol

Co-Gesic

CO-Gesic

Conacetol

Contac cough & sore throat formula

Contra-schmerz P

Coricidin

Coricidin D

Coricidin sinus

Cosutone

Croix blanche

Cuponol

Curadon

Curpol

Custodial

D oliprane

Dafalgan

Dapa

Dapa X-S

Darocet

Darvocet

Darvocet-N 50

Datril

Datril extra-strength

Daygrip

Demilets

Deminofen

Democyl

Demogripal

Desfebre

Dhamol

DHC Plus

Dial-a-gesic

Dial-alpha-gesic

Dimindol

Dirox

Disprol

Dolcor

Dolefin

Dolegrippin

Dolene ap-65

Dolene AP-65

Dolgesic

Doliprane

Dolko

Dolofugin

Doloreduct

Dolorfug

Dolorol forte

Dolorstop

Dolotec

Dolprone

Dol-stop

Dorocoff

Dresan

Dristan cold no drowsiness

Dristancito

Drixoral Plus

Duaneo

Dularin

Duorol

Duracetamol

Duradyne DHC

Durapan

Dymadon

Dymadon co

Dymadon Co

Dymadon forte

Dypap

Ecosetol

Elixodyne

Empracet

Endecon

Enelfa

Eneril

Esgic

Esgic-plus

Eu-med

Eu-Med

Excedrin

Excedrin caplets

Excedrin extra strength caplets

Excipain

Exdol

Exdol strong

Fanalgic

Farmadol

Febranine

Febrectal

Febrectol

Febrex

Febricet

Febridol

Febrilix

Febrin

Febrinol

febro-Gesic

Febro-Gesic

Febrolin

Femcet

Fendon

Fensum

Fepanil

Fever All

Feverall

Feverall junior strength

Feverall sprinkle caps junior strength

Fevor

Finimal

Finiweh

Fioricet

Fluparmol

Fortalidon P

Freka-cetamol

Gattaphen T

Gelocatil

Geluprane

Genapap

Genapap children's elixir

Genapap children's tablets

Genapap extra strength caplets

Genapap extra strength tablets

Genapap regular strength tablets

Genebs

Genebs extra strength caplets

Genebs regular strength tablets

Genebs X-tra

Geralgine-P

Gripin bebe

Gripin Bebe

Grippostad

Gynospasmine

Hedex

Helon N

Homoolan

Hycomine compound

Hydrocet

Hy-phen

Hy-Phen

Ildamol

Inalgex

Infadrops

Infants' feverall

Influbene N

Injectapap

Intensin

Janupap

Jin Gang

Junior disprol

Kataprin

KBio1_000660

Kinder finimal

Korum

Kratofin simplex

L024125

Labamol

Lekadol

Lemgrip

Lemsip

Lestemp

Liqiprine

Liquagesic

Liquigesic co

Liquiprin

Liquiprin children's elixir

Liquiprin infants" drops

Lonarid

Lonarid mono

Lonarid Mono

Lorcet-HD

Lortab

Lupocet

Lyteca

Lyteca syrup

Lyteca Syrup

Magnidol

Malex N

Malgis

Malidens

Maxadol

Medigesic plus

Medinol paediatric

Medocodene

Melabon infantil

Mexalen

Midol maximum strength

Midol PM night time formula

Midol regular strength

Midol teen formula

Migraleve yellow

Minafen

Minoset

Miralgin

Momentum

mono Praecimed

Multin

N-(4-Hydroxyphenyl)acetamide

N-Acetyl-4-aminophenol

N-acetyl-p-aminophenol

N-Acetyl-P-aminophenol

Naldegesic

NAPA

Napafen

Napap

Naprinol

NCX 701

Nealgyl

Nebs

NEBS

NeoCitran

Neodol

Neodolito

neo-Fepramol

Neo-Fepramol

Neopap

Neotrend

Neuridon

New cortal for children

NilnOcen

Nina

Nobedon

Nodolex

NO-Febril

Noral

Norcet

Norco

NSC3991

O-Acetaminophenol

Ofirmev

Oltyl

Oralgan

Oraphen-PD

Ortensan

Oxycet

Oxycocet

Oxycodone 2.5/apap 500

Oxycodone 5/apap 500

P-(acetylamino)Phenol

Paceco

Pacemo

Pacemol

Pacet

p-acetamidophenol

P-Acetamidophenol

p-acetaminophenol

P-Acetaminophenol

p-Acetylaminophenol

P-Acetylaminophenol

Pacimol

Paedialgon

Paedol

Painex

Paldesic

Pamol

Panacete

Panadeine

Panadeine co

Panadeine Co

Panadiene

panado-Co

Panado-Co

panado-co Caplets

Panadol

Panadol extra strength

Panadol junior strength caplets

Panadol maximum strength caplets

Panadol maximum strength tablets

Panale ve

Panaleve

Panamax

Panasorb

Panasorbe

Panets

Panex

Panodil

Panofen

Pantalgin

Papa-Deine

Papa-deine #3

Papa-deine #4

Paracemol

Paracenol

Paracet

Paracetamol

Paracétamol

Paracetamol al

Paracetamol antipanin P

Paracetamol basics

Paracetamol BC

Paracetamol DC

Paracetamol dr. schmidgall

Paracetamol fecofar

Paracetamol genericon

Paracetamol hanseler

Paracetamol harkley

Paracetamol heumann

Paracetamol hexal

Paracetamol italfarmaco

Paracetamol nycomed

Paracetamol PB

Paracetamol raffo

Paracetamol ratiopharm

Paracetamol rosch

Paracetamol saar

Paracetamol smithkline beecham

Paracetamol stada

Paracetamol von CT

Paracetamol winthrop

Paracetamole

Paracetamolo

Paracetamolum

Paracetanol

Paracetol

Paracin

Paracod

Paracodol

Parador

Paradrops

Parakapton

Parake

Paralen

Paralief

Paralink

Paralyoc

Paramol

Paramolan

Paranox

Parapan

Parasedol

Parasin

Paraspen

Para-suppo

Para-Suppo

Para-tabs

Parcetol

Parelan

Parmol

Parogal

Paroma

Pasolind

Pasolind N

PCM Paracetamol lichtenstein

Pediapirin

Pediatrix

Pedric

Percocet

Percocet-5

Percocet-demi

Percogesic with codeine

Perdolan mono

Perfalgan

Pe-tam

Pe-Tam

Phenaphen

Phenaphen caplets

Phenaphen Caplets

Phenaphen w/codeine

Phendon

Phenipirin

Phogoglandin

Phrenilin

Phrenilin forte

Phrenilin Forte

p-hydroxy-acetanilid

p-hydroxyacetanilide

P-Hydroxyacetanilide

p-hydroxyphenolacetamide

P-Hydroxyphenolacetamide

Pinex

Piramin

Pirinasol

Plicet

Polmofen

Predimol

Predualito

Prestwick_13

Prodol

Prompt

Prontina

Propacet

Propacet 100

Proval #3

Puernol

Pulmofen

Pyregesic-C

Pyrigesic

Pyrinazine

Pyromed

Quiet world

Redutemp

Reliv

Remedol

Rhinex D-lay tablets

Rivalgyl

Robigesic

Robitussin night relief

Rockamol plus

Rounox

Roxicet

Roxicet 5/500

Roxilox

RubieMol

Rubophen

Rupemol

Salzone

Sanicet

Sanicopyrine

Scanol

Scentalgyl

Scherzatabletten rezeptur 534

Schmerzex

Sedalito

Sedapap

Semolacin

Servigesic

Seskamol

Setakop

Setamol

Setol

Sifenol

Sinaspril

Sinedol

Sine-OFF sinus medicine caplets

Sinmol

Sinubid

SK-Apap

Snaplets-FR

Spalt fur die nacht

Spalt N

SPBio_002836

ST Joseph aspirin-free

ST Joseph aspirin-free for children

St. joseph cold tablets for children

St. joseph fever reducer

St. Joseph Fever Reducer

Stanback

Stopain

Sudafed severe cold formula

Sudafed sinus

Sunetheton

Supac

Supadol mono

Supofen

Suppap

Suppap-120

Suppap-325

Suppap-650

Supramol-m

Supramol-M

Synalgos-Dc-A

Synalgos-DC-a

Tabalgin

Tachiprina

Talacen

Tapanol

Tapanol extra strength caplets

Tapanol extra strength tablets

Tapar

Tavist allergy/sinus/headache

Tavist Allergy/Sinus/Headache

Tazamol

Temlo

Tempanal

Tempra

Tempra caplets

Tempra chewable tablets

Tempra d.s

Tempra drops

Tempra syrup

Tencon

Termacet

Termalgin

Termalgine

Termofren

TheraFlu

Tibinide

Tibizide

Tiffy

Tisin

Tisiodrazida

Titralgan

Tizide

Tocris-1706

Toximer P

Tralgon

Treupel mon

Treupel N

Treuphadol

Triad

Triaminic sore throat formula

Triaprin

Tricoton

Tussapap

Ty lenol

Tycolet

TYL

Tylenol

Tylenol (TN)

Tylenol allergy sinus

Tylenol arthritis extended relief

Tylenol caplets

Tylenol children's chewable tablets

Tylenol children's elixir

Tylenol children's suspension liquid

Tylenol drops

Tylenol elixir

Tylenol extra strength adult liquid pain reliever

Tylenol extra strength caplets

Tylenol extra strength gelcaps

Tylenol extra strength tablets

Tylenol gelcaps

Tylenol infants drops

Tylenol infants" suspension drops

Tylenol junior strength caplets

Tylenol junior strength chewable tablets

Tylenol regular strength caplets

Tylenol regular strength tablets

Tylenol tablets

Tylex

Tylex CD

Tylol

Tylox

Tylox-325

Tymol

Ultracet

Upsanol

Utragin

Valadol

Valgesic

Valorin

Valorin extra

Valorin Extra

Vanquish

Veralgina

Vermidon

Verpol

Viclor richet

Vicodin

Vicodin es

Vicodin HP

Vips

Viruflu

Vivimed

Volpan

Wygesic

Zatinol

Zolben

Dexmedetomidine

Approved, Vet_approved

Phase 2

113775-47-6

68602 5311068

Synonyms:

(+)-4-((S)-a,2,3-Trimethylbenzyl)imidazole

(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole

(+)-4-((S)-α,2,3-trimethylbenzyl)imidazole

(+)-medetomidine

(S)-medetomidine

113775-47-6

4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole

5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole

AC1NSJXT

C07450

CHEBI:4466

CHEMBL778

CID5311068

D00514

Dexmedetomidin

Dexmedetomidina

DEXMEDETOMIDINE

Dexmédétomidine

Dexmedetomidine (USAN/INN)

Dexmedetomidine hydrochloride

Dexmedetomidinum

Hospira brand OF dexmedetomidine hydrochloride

Hydrochloride, dexmedetomidine

Medetomidina [Spanish]

Medetomidine

Medetomidinum [Latin]

MPV 1440

MPV-1440

NCGC00025347-01

Precedex

PRECEDEX

Precedex (TN)

Tocris-2023

ZINC04632106

Acetylcholine

Approved

Phase 1, Phase 2

51-84-3

187

Synonyms:

2-(Acetyloxy)-N,N,N-trimethylethanaminium

Acetilcolina cusi

Acetyl choline ion

Acetylcholine bromide

Acetylcholine cation

acetylcholine chloride

Acetylcholine chloride

Acetylcholine Chloride

Acetylcholine fluoride

Acetylcholine hydroxide

Acetylcholine iodide

Acetylcholine L tartrate

Acetylcholine L-tartrate

Acetylcholine perchlorate

Acetylcholine picrate

Acetylcholine picrate (1:1)

Acetylcholine sulfate (1:1)

Acetylcholinium: acetyl-choline

ACh

Alcon brand OF acetylcholine chloride

Azetylcholin

Bournonville brand OF acetylcholine chloride

Bromide, acetylcholine

Bromoacetylcholine

Chloroacetylcholine

Choline acetate

Choline acetate (ester)

Choline acetic acid

Ciba vision brand OF acetylcholine chloride

Cusi, acetilcolina

Fluoride, acetylcholine

Hydroxide, acetylcholine

Iodide, acetylcholine

Iolab brand OF acetylcholine chloride

L-Tartrate, acetylcholine

Miochol

O-Acetylcholine

Perchlorate, acetylcholine

Anesthetics

Phase 2,Not Applicable

Antipyretics

Phase 2

Adrenergic Agonists

Phase 2

Anesthetics, Local

Phase 2

Neurotransmitter Agents

Phase 2,Phase 1

Central Nervous System Depressants

Phase 2,Not Applicable

Peripheral Nervous System Agents

Phase 2,Phase 1,Not Applicable

Adrenergic alpha-Agonists

Phase 2

Analgesics

Phase 2,Not Applicable

Adrenergic alpha-2 Receptor Agonists

Phase 2

Adrenergic Agents

Phase 2

Hypnotics and Sedatives

Phase 2

Analgesics, Non-Narcotic

Phase 2

Acetylcholine Release Inhibitors

Phase 1, Phase 2

Botulinum Toxins, Type A

Phase 1, Phase 2

Cholinergic Agents

Phase 1, Phase 2

abobotulinumtoxinA

Phase 1, Phase 2

Neuromuscular Agents

Phase 1, Phase 2

onabotulinumtoxinA

Phase 1, Phase 2

Botulinum Toxins

Phase 1, Phase 2

Fentanyl

Approved, Illicit, Investigational, Vet_approved

Not Applicable

437-38-7

3345

Synonyms:

1-Phenethyl-4-(N-phenylpropionamido)piperidine

1-phenethyl-4-N-propionylanilinopiperidine

1-Phenethyl-4-N-propionylanilinopiperidine

437-38-7

5-22-08-00049 (Beilstein Handbook Reference)

80832-90-2

990-73-8 (citrate)

AC1L1FQ2

Actiq

BIDD:GT0555

BRN 0494484

Cephalon brand OF fentanyl buccal oravescent

CHEBI:119915

CHEMBL596

CID3345

D00320

DB00813

Duragesic

Duragesic (TN)

Duragesic-100

Duragesic-12

Duragesic-25

Duragesic-50

Duragesic-75

Durogesic

EINECS 207-113-6

Fentanest

Fentanil

Fentanil [DCIT]

Fentanila

Fentanila [INN-Spanish]

Fentanilo

fentanyl

Fentanyl

Fentanyl (JAN/USAN/INN)

Fentanyl [INN:BAN]

Fentanyl CII

Fentanyl citrate

Fentanyl-100

Fentanyl-12

Fentanyl-25

Fentanyl-50

Fentanyl-75

Fentanylum

Fentanylum [INN-Latin]

Fentora

HSDB 3329

IONSYS

Janssen pharmaceutica brand OF fentanyl

JNS020QD

L001275

LS-124439

Matrifen

MolPort-003-847-369

N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide

N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide

N-(1-phenethyl-4-piperidyl)propionanilide

N-(1-Phenethyl-4-piperidyl)propionanilide

N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide

N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide

N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide

N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide

Nasalfent

NCGC00168252-01

N-phenethyl-4-(N-propionylanilino)piperidine

N-Phenethyl-4-(N-propionylanilino)piperidine

N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide

N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide

N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide

Oprea1_152073

Oprea1_207148

PDSP1_000860

PDSP2_000846

Pentanyl

Phentanyl

Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)

R 4263

Rapinyl

Sentonil

Sublimase

Sublimaze

Transmucosal oral fentanyl citrate

UNII-UF599785JZ

Morphine

Approved, Investigational

Not Applicable

57-27-2

5288826

Synonyms:

(-)(5.alpha.,6.alpha.)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol

(-)-Heroin hydrochloride

(−)-morphine

(-)-Morphine

(-)Morphine sulfate

(5a,6a)-17-Methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol

(5a,6a)-didehydro-4,5-Epoxy-17-methylmorphinan-3,6-diol

(5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol

(5alpha,6alpha)-17-Methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol

(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol

(5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol

(5alpha,6alpha)-didehydro-4,5-Epoxy-17-methylmorphinan-3,6-diol

(5alpha,6alpha)-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol

(5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol

(5R,6S,9R,13S,14R)-4,5-Epoxy-N-methyl-7-morphinen-3,6-diol

(5α,6α)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol

(5α,6α)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol

(7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol

(7R,7AS,12BS)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol

(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL

17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol

4,5alpha-Epoxy-17-methyl-7-morphinen-3,6alpha-diol

47106-99-0

4-methyl-(13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol

57-27-2

6211-15-0 (sulfate (2:1) (salt) pentahydrate)

64-31-3

64-31-3 (sulfate (2:1) (salt) anhydrous)

7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol

7,8-Didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol

8053-16-5

85201-37-2

Anhydrous morphine

Apokyn

Astramorph PF

Avinza

BIDD:GT0147

C01516

CCRIS 5762

CHEBI:17303

CHEMBL70

Chloride, morphine

CID5288826

Contin, MS

Cube juice

D-(-)-Morphine

DB00295

DEA No. 9300

Depodur

DepoDur

Diacetylmorphine hydrochloride

Diamorphine hydrochloride

Dolcontin

Dreamer

Dulcontin

Duramorph

Duramorph PF

Duromorph

EINECS 200-320-2

Epimorph

Hard stuff

Heroin hydrochloride

Heroine hydrochloride

Hocus

HSDB 2134

Infumorph

Kadian

l-Morphine

LS-91748

M.O.S

Meconium

M-Eslon

MOI

MolPort-003-849-273

morfina

Morfina

Morfina [Italian]

Morphia

Morphin

Morphin [German]

Morphina

Morphina [Italian]

morphine

Morphine [BAN]

Morphine chloride

Morphine Extra-Forte

Morphine Forte

Morphine H.P

Morphine sulfate

Morphine Sulfate

MORPHINE SULFATE

Morphine sulfate (2:1), anhydrous

Morphine sulfate (2:1), pentahydrate

MORPHINE, (5A,6A)-7,8-DIDEHYDRO-4,5-EPOXY-17-METHYLMORPHINIAN-3,6-DIOL, MORPHIUM, MORPHIA, DOLCONTIN, DUROMORPH, MORPHINA, NEPENTHE

Morphinism

Morphinum

Morphitec

Morphium

Morpho

Moscontin

Ms Contin

MS Contin

Ms Emma

MS/L

MS/S

MSIR

nchembio.317-comp1

nchembio.64-comp1

Nepenthe

NSC11441

O,O'-Diacetylmorphine hydrochloride

OMS Concentrate

Oramorph SR

Ospalivina

Rescudose

RMS

RMS Uniserts

Roxanol

Roxanol 100

Roxanol UD

SDZ 202-250

SDZ202-250

Statex

Statex Drops

Statex SR

Sulfate, morphine

UNII-76I7G6D29C

Unkie

Adjuvants, Anesthesia

Not Applicable

Analgesics, Opioid

Not Applicable

Narcotics

Not Applicable

Anesthetics, Intravenous

Not Applicable

Anesthetics, General

Not Applicable

Interventional clinical trials:

(show top 50) (show all 56)

#	Name	Status	NCT ID	Phase	Drugs
1	The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate Surgery	Recruiting	NCT02953145	Phase 4	Tisseel
2	Oral Cleft Prevention Program	Completed	NCT00397917	Phase 3	Folic acid: 4 mg versus 0.4 mg per day
3	Silicone Gel in the Treatment of Cleft Lip Scars	Completed	NCT03314090	Phase 3	Silicone Gels
4	Oral Cleft Prevention Trial in Brazil	Completed	NCT00098319	Phase 3	Folic acid (0.4mg vs. 4.0mg)
5	Bone Tissue Engineering With Dental Pulp Stem Cells for Alveolar Cleft Repair	Not yet recruiting	NCT03766217	Phase 3
6	Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?	Completed	NCT00930124	Phase 2
7	Cleft Palate Surgery and Speech Development	Completed	NCT00004639	Phase 2
8	Suprazygomatic Block in Cleft Palate Surgery in Children	Completed	NCT03412474	Phase 2	Bupivacaine;Dexmedetomidine;paracetamol
9	Improvement of the Appearance of Cleft Lip Scars Using Botox	Recruiting	NCT02247193	Phase 1, Phase 2	Botulinum Toxin Type A;Normal Saline Injection
10	One-Piece Le Fort I Osteotomy Versus Segmental Le Fort I Osteotomy	Unknown status	NCT01871623	Not Applicable
11	Alveolar Bone Grafting Outcome Between Patient With and Without Orthodontic Treatment	Unknown status	NCT02454998	Not Applicable
12	Osteogenesis and Dental Eruption Through Electrical Stimuli	Unknown status	NCT00975208
13	Functional Nasal Surgery at the Time of Le Fort I Osteotomy: A Prospective, Single-blind, Randomized Trial	Unknown status	NCT01883687	Not Applicable
14	IAN Injury After BSSO in Oral Clefts	Unknown status	NCT01875965
15	Validation of a Production Method of Stem Cell Isolated From the Nasal Cavity for an Innovative Cell Therapy of Cleft Palate	Unknown status	NCT02900014	Not Applicable
16	Ultrasound Diagnosis of Cleft Lip and Palate	Completed	NCT03582111
17	A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate	Completed	NCT00156442
18	Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients	Completed	NCT01932164	Not Applicable
19	Electromyographic Analysis of the Masticatory Muscles in Cleft Lip and Palate Children With Temporomandibular Disorders	Completed	NCT03308266
20	Articulation and Phonology in Children With Unilateral Cleft Lip and Palate	Completed	NCT00829101
21	Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients	Completed	NCT02329509	Not Applicable
22	Effect Of Combination of Morphine+Fentanyl on Emergence Delirium in Patients of Cleft Lip and Palate Repair	Completed	NCT03010540	Not Applicable	MORPHINE PLUS FENTANYL;Fentanyl
23	Assessing the Results of Lip Surgery in Patients With Cleft Lip and Palate	Completed	NCT00070811
24	Efficacy of Maxillo-facial Treatment on Cleft Lip and Palate Patients Faces: Aesthetic Considerations	Completed	NCT03395015
25	Periodontal Changes Following Mid Maxillary Distraction	Completed	NCT03686761	Not Applicable
26	Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes	Completed	NCT01380171
27	Tissue Engineered Constructs for Alveolar Cleft Repair	Completed	NCT03563495	Not Applicable
28	Relational Development in Children With Cleft Lips and Palates: Influence of the Waiting Period Prior to the First Surgical Intervention and the Parents' Psychological Perception of the Abnormality	Completed	NCT00993993
29	Systematic Pediatric Care for Oral Clefts - South America	Completed	NCT00097149	Not Applicable
30	Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences	Completed	NCT00340964
31	Tympanometric Analysis in Cleft Palate	Completed	NCT01820689	Not Applicable
32	Study of the Experiences and Needs of Parents Continuing a Pregnancy Following a Prenatal Diagnosis of Holopresencephaly	Completed	NCT00005016
33	Svangerskap, Arv, Og Miljo (Pregnancy, Heredity and Environment)	Completed	NCT00340977
34	Child and Infant Learning Project	Completed	NCT00077831
35	Clinical Effectiveness of Late Maxillary Protraction for Cleft Lip and Palate	Recruiting	NCT02789787
36	Three Dimensional Facial Growth Analysis	Recruiting	NCT03514563
37	Evaluation of the Clinical Effectiveness of Naso-alveolar Molding (NAM) Versus Computer Aided Design NAM (CAD/NAM) in Infants With Bilateral Cleft Lip and Palate: A Randomized Clinical Trial	Recruiting	NCT02881606	Not Applicable
38	Otologic and Rhinologic Outcomes in Children With Clef Palate	Recruiting	NCT03708406
39	Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing	Recruiting	NCT03065686	Not Applicable
40	Prospective Data-collection System for the Comprehensive Appraisal of Cleft Care	Recruiting	NCT02702869
41	Ability of a Molecule (Prima) to Restore Physiological Differentiation in Epithelium Expressing Gene p63	Recruiting	NCT02896387
42	Extended Criteria For Fetal Myelomeningocele Repair	Recruiting	NCT02664207	Not Applicable
43	Targeting Surgeons' Decision-Making for Cleft Lip Surgery	Recruiting	NCT03537976	Not Applicable
44	Nasoalveolar Molding for Egyptian Cleft Lip Palate Infants	Active, not recruiting	NCT03029195	Not Applicable
45	Efficiency of Novel Nasoalveolar Molding Techniques on Parents' Satisfaction and Short Term Treatment Outcomes in Unilateral Cleft Lip and Palate Infants: A Randomized Controlled Trial	Active, not recruiting	NCT02845193	Not Applicable
46	Follow Ups of Parents With Infants With Cleft Lip and Palate	Active, not recruiting	NCT02415361	Not Applicable
47	Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study	Active, not recruiting	NCT03165331	Not Applicable
48	Parent's Satisfaction and Evaluation of Postsurgical Outcomes in Unilateral Cleft Lip / Palate Newly Born Infants With / Without Vacuum Formed Nasoalveolar Molding Aligners : A Controlled Clinical Trial	Not yet recruiting	NCT03011489	Not Applicable
49	Oral Hygiene and Connected Toothbrush Before Alveolar Bone Graft for Cleft Lip and Palate	Not yet recruiting	NCT03750708	Not Applicable
50	Evaluation of Arch Dimensions of Children With Surgically Repaired Unilateral Cleft Lip and Palate	Not yet recruiting	NCT03219021

Search NIH Clinical Center for Cleft Lip/palate

Sources

Genetic Tests for Cleft Lip/palate

Genetic tests related to Cleft Lip/palate:

#	Genetic test	Affiliating Genes
1	Cleft Lip/palate ²⁹

Sources

Anatomical Context for Cleft Lip/palate

MalaCards organs/tissues related to Cleft Lip/palate:

⁴¹

Bone, Heart, Skin, Kidney, Lung, Breast, Thymus

Sources

Publications for Cleft Lip/palate

Articles related to Cleft Lip/palate:

(show top 50) (show all 1774)

#	Title	Authors	Year
1	Child development skills and language in toddlers with cleft lip and palate. ( 30554694 )	Cavalheiro MG...Maximino LP	2019
2	Bilateral suprazygomatic maxillary nerve blocks vs. infraorbital and palatine nerve blocks in cleft lip and palate repair: A double-blind, randomised study. ( 30308523 )	Echaniz G...Bosenberg A	2019
3	The Difference in Cervical Vertebral Skeletal Maturation between Cleft Lip/Palate and Non-Cleft Lip/Palate Orthodontic Patients. ( 29619373 )	Batwa W....Zawawi K.H.	2018
4	Rethinking isolated cleft lip and palate as a syndrome. ( 29500156 )	Koruyucu M....Vieira A.R.	2018
5	Effects of Nasoalveolar Molding Therapy on Alveolar and Palatal Cleft Deformities in Unilateral and Bilateral Cleft Lip and Palate. ( 29381641 )	Isik Aslan B....A9AsA1ncA1 N.	2018
6	Cleft Lip and Palate in CHARGE Syndrome: Phenotypic Features That Influence Management. ( 29437513 )	Isaac K.V....Mulliken J.B.	2018
7	The Impact of Maxillary Advancement on Consonant Proficiency in Patients With Cleft Lip and Palate, Lay Listeners' Opinion, and Patients' Satisfaction With Speech. ( 29949386 )	Hagberg E....Lohmander A.	2018
8	A case of cleft lip and palate with severe maxillary retrognathism treated by distraction osteogenesis and custom made intraoral rapid maxillary expansion appliance: A 2-year follow-up of retention. ( 29937663 )	Singaraju G.S....Kanabaddy S.R.	2018
9	Acoustic analysis of misarticulated trills in cleft lip and palate children. ( 29960457 )	Vikram C.M....Mahadeva Prasanna S.R.	2018
10	Teeth agenesis evaluation in an Italian sample of complete unilateral and bilateral cleft lip and palate patients. ( 29388416 )	De Stefani A....Gracco A.	2018
11	Long-Term Skeletal Changes After Maxillary Distraction Osteogenesis in Growing Children With Cleft Lip/Palate. ( 29461366 )	Liu K....Zhou N.	2018
12	3D Assessment of Nasolabial Appearance in Patients With Complete Unilateral Cleft Lip and Palate. ( 29351025 )	Bagante I....Akota I.	2018
13	The use of throat packs in pediatric cleft lip/palate surgery: a retrospective study. ( 29473105 )	Smarius B.J.A....Breugem C.C.	2018
14	A Case of Ankyloblepharon-ectodermal Defects-cleft Lip/palate-syndrome with Choanal Atresia and Skin Erosions: Phenotypic Variability of TP63-related Disorders. ( 29956718 )	Niculescu L....Giehl K.A.	2018
15	Bone-anchored maxillary protraction in a patient with complete cleft lip and palate: A case report. ( 29407507 )	Garib D....de Clerck H.	2018
16	Tooth-borne distraction osteogenesis versus conventional Le Fort I in maxillary advancement of cleft lip and palate patients. ( 29388417 )	Jamilian A....Perillo L.	2018
17	BRCA1 and BRCA2 gene variants and nonsyndromic cleft lip/palate. ( 29921024 )	Rodriguez N....Letra A.	2018
18	Novel <i>TBX22</i> mutations in Chinese nonsyndromic cleft lip/palate families. ( 29932061 )	Dai J....Yang Y.	2018
19	Influence of involuntary facial expressions on reproducibility of 3D stereophotogrammetry in children with and without complete unilateral cleft lip and palate from 3 to 18A months of age. ( 29943366 )	Brons S....Kuijpers-Jagtman A.M.	2018
20	Comprehensive Genetic Screening Recommended for Nonsyndromic Cleft Lip/Palate: Even in the absence of any signs of a syndrome, patients with cleft lip/palate may still carry a mutation in a gene linked to a syndrome and should receive comprehensive genetic testing. ( 29878711 )		2018
21	PVR/CD155 Ala67Thr Mutation and Cleft Lip/Palate. ( 29381645 )	Vieira A.R....Orioli I.M.	2018
22	Strong Association of C677T Polymorphism of Methylenetetrahydrofolate Reductase Gene With Nosyndromic Cleft Lip/Palate (nsCL/P). ( 29371764 )	Rai V.	2018
23	Single-Stage Primary Cleft Lip and Palate Repair: A Review of the Literature. ( 29944528 )		2018
24	A Comparative Evaluation of Efficacy and Efficiency of Grayson's Presurgical Nasoalveolar Molding Technique in Patients with Complete Unilateral Cleft Lip and Palate with Those Treated with Figueroa's Modified Technique. ( 29962760 )		2018
25	Assessment of facial asymmetry before and after the surgical repair of cleft lip in unilateral cleft lip and palate cases. ( 28967531 )		2018
26	3D-Printed Models of Cleft Lip and Palate for Surgical Training and Patient Education. ( 29437509 )		2018
27	A novel non-coding RNA within an intron of CDH2 and association of its SNP with non-syndromic cleft lip and palate. ( 29524576 )		2018
28	Evaluation of Airway Volume in Cleft Lip and Palate Following Nasoalveolar Molding. ( 29944553 )		2018
29	Minimally invasive versus standard approach in LeFort 1 osteotomy in patients with history of cleft lip and palate. ( 29408322 )		2018
30	Three-dimensional radiological evaluation of secondary alveolar bone grafting in cleft lip and palate patients: a systematic review. ( 29947253 )		2018
31	A Pediatrician's Guide to Communication Disorders Secondary to Cleft Lip/Palate. ( 29173718 )		2018
32	Quantifying Soft Tissue Shape and Symmetry: Patients with Cleft Lip/Palate and Facial Paralysis. ( 29707466 )		2018
33	The Effect of Nasoalveolar Molding on Nasal Airway Anatomy: A 9-Year Follow-up of Patients With Unilateral Cleft Lip and Palate. ( 29356619 )		2018
34	Impact of Temporomandibular Disorders and Sleep Bruxism on Oral Health-Related Quality of Life of Individuals With Complete Cleft Lip and Palate. ( 30074958 )	Silva FCD...Soares S	2018
35	Caregiver-Reported Outcomes and Barriers to Care among Patients with Cleft Lip and Palate. ( 30489528 )	Bennett KG...Waljee JF	2018
36	Associated parameters of canine impaction in patients with unilateral cleft lip and palate after secondary alveolar bone grafting: a retrospective study. ( 30500916 )	Hereman V...Verdonck A	2018
37	A Novel Approach for the Reconstruction of Premaxilla by Archwise Distraction in Bilateral Cleft Lip and Palate. ( 30507876 )	Yilmaz HN...Erverdi N	2018
38	The role of external aetiological factors in dental anomalies in non-syndromic cleft lip and palate patients. ( 30511277 )	Korolenkova MV...Udalova NV	2018
39	Early Weight Gain in Infants With Cleft Lip and Palate Treated With and Without Nasoalveolar Molding: A Retrospective Study. ( 30514093 )	Woods SM...Doyle LM	2018
40	Quality of life and mastication in denture wearers and cleft lip and palate adults. ( 30517426 )	Palmeiro MRL...Shinkai RSA	2018
41	Importance of glottis landmarks for the assessment of cleft lip and palate speech intelligibility. ( 30522275 )	Kalita S...Dandapat S	2018
42	The effect of facial expression on facial symmetry in surgically managed unilateral cleft lip and palate patients (UCLP). ( 30522896 )	Al Rudainy D...Ayoub A	2018
43	Clinical Outcomes Utilizing a "Modified Latham" Appliance for Presurgical Infant Orthopedics in Patients With Unilateral Complete Cleft Lip and Palate. ( 30526003 )	Jodeh DS...Rottgers SA	2018
44	A Programmable Expander for Patients With Cleft Lip and Palate. ( 30526006 )	Torres A...Yen S	2018
45	Comment on Malmborn, Becker, and Klintö: Problems With Reliability of Speech Variables for Use in Quality Registries for Cleft Lip and Palate-Experiences From the Swedish Cleft Lip and Palate Registry, CPCJ 2018. ( 30526009 )	Lohmander A	2018
46	Secondary alveolar bone grafting in cleft lip and palate: A comparative analysis of donor site morbidity in different age groups. ( 30527380 )	Brudnicki A...Sawicka E	2018
47	Combined Primary Cleft Lip and Palate Repair: Is It Safe? ( 30531281 )	Kantar RS...Flores RL	2018
48	Outcome of Patients with Complete Unilateral Cleft Lip and Palate: 20-Years Follow-up of Treatment Protocol. ( 30531628 )	Pai BC...Lo LJ	2018
49	OSC10: Observation of the Teeth Position in Cleft Lip and Palate Patients using Three-Dimensional Assessment. ( 30532403 )	Manjin Z...Hisashi T	2018
50	Prenatal diagnosis of cleft lip and cleft lip palate - a case series. ( 30534664 )	Marginean C...Marginean MO	2018

Sources

Genes for Cleft Lip/palate

Genes related to Cleft Lip/palate (9 elite genes):

(show all 39)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	DLX4	Distal-Less Homeobox 4	Protein Coding	357.08	Causative germline mutation ⁵⁹ GeneCards inferred via : Publications (show sections)
2	TP63	Tumor Protein P63	Protein Coding	75.27	Susceptibility factor ⁵⁹ GeneCards inferred via : Disorders Publications Summaries Variants (show sections)
3	NECTIN1	Nectin Cell Adhesion Molecule 1	Protein Coding	62.41	Susceptibility factor ⁵⁹ GeneCards inferred via : Disorders Publications Variants (show sections)
4	IRF6	Interferon Regulatory Factor 6	Protein Coding	52.34	Susceptibility factor ⁵⁹ GeneCards inferred via : Disorders Publications (show sections)
5	MSX1	Msh Homeobox 1	Protein Coding	42.97	Susceptibility factor ⁵⁹ GeneCards inferred via : Publications (show sections)
6	CDH1	Cadherin 1	Protein Coding	32.08	Susceptibility factor ⁵⁹ GeneCards inferred via : Publications (show sections)
7	ARHGAP29	Rho GTPase Activating Protein 29	Protein Coding	32.08	Susceptibility factor ⁵⁹ GeneCards inferred via : Publications (show sections)
8	YAP1	Yes Associated Protein 1	Protein Coding	27.33	GeneCards inferred via : Disorders Variants (show sections)
9	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	26.76	GeneCards inferred via : Disorders Publications (show sections)
10	DLG1	Discs Large MAGUK Scaffold Protein 1	Protein Coding	25	Susceptibility factor ⁵⁹
11	BMP4	Bone Morphogenetic Protein 4	Protein Coding	25	Susceptibility factor ⁵⁹
12	INTU	Inturned Planar Cell Polarity Protein	Protein Coding	18.24	GeneCards inferred via : Disorders (show sections)
13	WDR35	WD Repeat Domain 35	Protein Coding	18.24	GeneCards inferred via : Disorders (show sections)
14	EEC1	Ectrodactyly, Ectodermal Dysplasia And Cleft Lip/Palate Syndrome 1	Genetic Locus	18.04	GeneCards inferred via : Publications Gene name (show sections)
15	SPECC1L	Sperm Antigen With Calponin Homology And Coiled-Coil Domains 1 Like	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
16	WDR19	WD Repeat Domain 19	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
17	WNT3	Wnt Family Member 3	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
18	WDR60	WD Repeat Domain 60	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
19	MEIS2	Meis Homeobox 2	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
20	NEK1	NIMA Related Kinase 1	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
21	MID1	Midline 1	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
22	TCTEX1D2	Tctex1 Domain Containing 2	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
23	WDR34	WD Repeat Domain 34	Protein Coding	17.9	GeneCards inferred via : Disorders (show sections)
24	TGFA	Transforming Growth Factor Alpha	Protein Coding	17.54	GeneCards inferred via : Publications Summaries (show sections)
25	EEC2	Ectrodactyly, Ectodermal Dysplasia And Cleft Lip/Palate Syndrome 2	Genetic Locus	8.67	GeneCards inferred via : Gene name (show sections)
26	IFT80	Intraflagellar Transport 80	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
27	IFT172	Intraflagellar Transport 172	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
28	IFT140	Intraflagellar Transport 140	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
29	KIAA0586	KIAA0586	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
30	CEP120	Centrosomal Protein 120	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
31	DYNC2LI1	Dynein Cytoplasmic 2 Light Intermediate Chain 1	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
32	DYNC2H1	Dynein Cytoplasmic 2 Heavy Chain 1	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
33	IFT81	Intraflagellar Transport 81	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
34	TTC21B	Tetratricopeptide Repeat Domain 21B	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
35	IFT52	Intraflagellar Transport 52	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
36	IFT43	Intraflagellar Transport 43	Protein Coding	7.9	GeneCards inferred via : Disorders (show sections)
37	MTHFR	Methylenetetrahydrofolate Reductase	Protein Coding	7.77	GeneCards inferred via : Publications (show sections)
38	TBX22	T-Box 22	Protein Coding	7.63	GeneCards inferred via : Publications (show sections)
39	FOXE1	Forkhead Box E1	Protein Coding	7.63	GeneCards inferred via : Publications (show sections)

Sources

Variations for Cleft Lip/palate

Sources

Expression for Cleft Lip/palate

Search GEO for disease gene expression data for Cleft Lip/palate.

Sources

Pathways for Cleft Lip/palate

Pathways related to Cleft Lip/palate according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Mesodermal Commitment Pathway ¹ Show member pathways Endoderm Differentiation ¹	12.19	BMP4 FGFR1 WNT3 YAP1
2	Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.68	BMP4 IRF6 MSX1 TP63
3	Hippo signaling pathway ³⁷	11.54	BMP4 CDH1 DLG1 WNT3 YAP1
4	Neural Crest Differentiation ¹	11.47	BMP4 CDH1 FGFR1 MSX1
5	Adherens junction ³⁷	11.4	CDH1 FGFR1 NECTIN1
6	Intraflagellar transport ⁶⁶	11.11	WDR19 WDR35 WDR60
7	Hypothetical Craniofacial Development Pathway ¹	9.7	ARHGAP29 IRF6 TP63

Sources

GO Terms for Cleft Lip/palate

Cellular components related to Cleft Lip/palate according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	apical junction complex	GO:0043296	9.26	CDH1 NECTIN1
2	pericentriolar material	GO:0000242	9.16	NEK1 WDR60
3	intraciliary transport particle A	GO:0030991	8.96	WDR19 WDR35
4	ciliary tip	GO:0097542	8.8	WDR19 WDR35 WDR60

Biological processes related to Cleft Lip/palate according to GeneCards Suite gene sharing:

(show all 30)

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of transcription by RNA polymerase II	GO:0000122	9.98	BMP4 DLG1 DLX4 FGFR1 MEIS2 MSX1
2	embryonic digit morphogenesis	GO:0042733	9.74	BMP4 INTU MSX1
3	odontogenesis of dentin-containing tooth	GO:0042475	9.73	BMP4 MSX1 TP63
4	cilium assembly	GO:0060271	9.72	INTU NEK1 WDR19 WDR35 WDR60
5	embryonic skeletal system morphogenesis	GO:0048704	9.71	BMP4 DLG1 WDR60
6	ureteric bud development	GO:0001657	9.7	BMP4 DLG1 FGFR1
7	intraciliary transport involved in cilium assembly	GO:0035735	9.69	WDR19 WDR35 WDR60
8	keratinocyte differentiation	GO:0030216	9.67	INTU IRF6 TP63 YAP1
9	camera-type eye morphogenesis	GO:0048593	9.65	BMP4 NECTIN1
10	embryonic forelimb morphogenesis	GO:0035115	9.65	MSX1 TP63 WNT3
11	middle ear morphogenesis	GO:0042474	9.64	FGFR1 MSX1
12	anterior/posterior axis specification	GO:0009948	9.63	BMP4 WNT3
13	establishment of planar polarity	GO:0001736	9.63	INTU TP63
14	pituitary gland development	GO:0021983	9.63	BMP4 CDH1 MSX1
15	epithelial to mesenchymal transition involved in endocardial cushion formation	GO:0003198	9.62	BMP4 MSX1
16	intraciliary retrograde transport	GO:0035721	9.62	WDR19 WDR35
17	organ induction	GO:0001759	9.61	BMP4 FGFR1
18	smooth muscle tissue development	GO:0048745	9.61	BMP4 DLG1
19	mammary gland epithelium development	GO:0061180	9.6	MSX1 WNT3
20	paraxial mesoderm development	GO:0048339	9.59	FGFR1 YAP1
21	bud elongation involved in lung branching	GO:0060449	9.58	BMP4 YAP1
22	anatomical structure formation involved in morphogenesis	GO:0048646	9.58	BMP4 TP63 WNT3
23	cell morphogenesis	GO:0000902	9.56	MSX1 WDR19 WNT3 YAP1
24	BMP signaling pathway involved in heart development	GO:0061312	9.55	BMP4 MSX1
25	cell projection organization	GO:0030030	9.55	INTU NEK1 WDR19 WDR35 WDR60
26	cloacal septation	GO:0060197	9.49	BMP4 TP63
27	embryonic hindlimb morphogenesis	GO:0035116	9.26	BMP4 MSX1 TP63 WNT3
28	embryonic limb morphogenesis	GO:0030326	9.02	BMP4 FGFR1 MSX1 TP63 WDR19
29	multicellular organism development	GO:0007275	10.13	BMP4 DLX4 INTU MEIS2 MSX1 TP63
30	positive regulation of transcription, DNA-templated	GO:0045893	10.04	BMP4 CDH1 IRF6 TP63 YAP1

Molecular functions related to Cleft Lip/palate according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	sequence-specific DNA binding	GO:0043565	9.02	DLX4 IRF6 MEIS2 MSX1 TP63

Sources

Sources for Cleft Lip/palate

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia

Cleft Lip/palate (FLP)

Aliases & Classifications for Cleft Lip/palate

MalaCards integrated aliases for Cleft Lip/palate:

Classifications:

External Ids:

Summaries for Cleft Lip/palate

Related Diseases for Cleft Lip/palate

Diseases related to Cleft Lip/palate via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Cleft Lip/palate:

Symptoms & Phenotypes for Cleft Lip/palate

MGI Mouse Phenotypes related to Cleft Lip/palate:

Drugs & Therapeutics for Cleft Lip/palate

Drugs for Cleft Lip/palate (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Genetic Tests for Cleft Lip/palate

Genetic tests related to Cleft Lip/palate:

Anatomical Context for Cleft Lip/palate

MalaCards organs/tissues related to Cleft Lip/palate:

Publications for Cleft Lip/palate

Articles related to Cleft Lip/palate:

Genes for Cleft Lip/palate

Genes related to Cleft Lip/palate (9 elite genes):

Variations for Cleft Lip/palate

Expression for Cleft Lip/palate

Pathways for Cleft Lip/palate

Pathways related to Cleft Lip/palate according to GeneCards Suite gene sharing:

GO Terms for Cleft Lip/palate

Cellular components related to Cleft Lip/palate according to GeneCards Suite gene sharing:

Biological processes related to Cleft Lip/palate according to GeneCards Suite gene sharing:

Molecular functions related to Cleft Lip/palate according to GeneCards Suite gene sharing:

Sources for Cleft Lip/palate