MCID: CLM004
MIFTS: 16

Climatic Droplet Keratopathy

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Climatic Droplet Keratopathy

MalaCards integrated aliases for Climatic Droplet Keratopathy:

Name: Climatic Droplet Keratopathy 58
Honey-Droplet Corneal Dystrophy 58

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 58  
Rare eye diseases


External Ids:

ICD10 via Orphanet 33 H18.5
Orphanet 58 ORPHA98958

Summaries for Climatic Droplet Keratopathy

MalaCards based summary : Climatic Droplet Keratopathy, also known as honey-droplet corneal dystrophy, is related to keratopathy and corneal disease. An important gene associated with Climatic Droplet Keratopathy is JCHAIN (Joining Chain Of Multimeric IgA And IgM). Affiliated tissues include eye and skin.

Related Diseases for Climatic Droplet Keratopathy

Diseases related to Climatic Droplet Keratopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 15)
# Related Disease Score Top Affiliating Genes
1 keratopathy 10.9
2 corneal disease 10.5
3 keratitis, hereditary 10.4
4 bullous keratopathy 10.3
5 trachoma 10.3
6 cataract 10.3
7 exfoliation syndrome 10.1
8 leprosy 3 10.1
9 hypopyon 10.1
10 lepromatous leprosy 10.1
11 pinguecula 10.1
12 corneal degeneration 10.1
13 amyloidosis 10.1
14 interstitial keratitis 10.1
15 hansen's disease 10.1

Graphical network of the top 20 diseases related to Climatic Droplet Keratopathy:



Diseases related to Climatic Droplet Keratopathy

Symptoms & Phenotypes for Climatic Droplet Keratopathy

Drugs & Therapeutics for Climatic Droplet Keratopathy

Search Clinical Trials , NIH Clinical Center for Climatic Droplet Keratopathy

Genetic Tests for Climatic Droplet Keratopathy

Anatomical Context for Climatic Droplet Keratopathy

MalaCards organs/tissues related to Climatic Droplet Keratopathy:

40
Eye, Skin

Publications for Climatic Droplet Keratopathy

Articles related to Climatic Droplet Keratopathy:

(show top 50) (show all 71)
# Title Authors PMID Year
1
Spontaneous late reopening of a successfully operated and closed full-thickness macular hole. 61
32195442 2020
2
Phospholipidomic Studies in Human Cornea From Climatic Droplet Keratopathy. 61
28401586 2017
3
Damaging Effects of Ultraviolet Radiation on the Cornea. 61
27935054 2017
4
Climatic droplet keratopathy: an old disease in new clothes. 61
25626588 2015
5
Climatic Droplet Keratopathy in Argentina: Involvement of Environmental Agents in Its Genesis Which Would Open the Prospect for New Therapeutic Interventions. 61
26451372 2015
6
Exfoliation syndrome in sub-Saharan Africa. 61
24844849 2014
7
Ocular morbidity among refugees in Southwest Ethiopia. 61
25183929 2014
8
Ultraviolet light and ocular diseases. 61
23722672 2014
9
In vivo confocal microscopy of climatic droplet keratopathy. 61
23980269 2013
10
Genetic background and climatic droplet keratopathy incidence in a Mapuche population from Argentina. 61
24040292 2013
11
In vivo confocal microscopy study of climatic droplet keratopathy. 61
22538217 2012
12
Pro-inflammatory cytokines and gelatinases in climatic droplet keratopathy. 61
22570354 2012
13
Altered expression of matrix metalloproteinases and their tissue inhibitors as possible contributors to corneal droplet formation in climatic droplet keratopathy. 61
19900203 2011
14
The effect of vitamin C deficiency and chronic ultraviolet-B exposure on corneal ultrastructure: a preliminary investigation. 61
22171156 2011
15
Cis-urocanic acid inhibits SAPK/JNK signaling pathway in UV-B exposed human corneal epithelial cells in vitro. 61
21921982 2011
16
Accumulation of D-beta-aspartic acid-containing proteins in age-related ocular diseases. 61
20564555 2010
17
Immunohistochemical localisation of D-beta-aspartic acid-containing proteins in climatic droplet keratopathy. 61
19276099 2009
18
Quantitative analysis of N-linked glycoproteins in tear fluid of climatic droplet keratopathy by glycopeptide capture and iTRAQ. 61
19714880 2009
19
Amniotic membrane transplant with superficial keratectomy in superficial corneal degenerations: efficacy in a rural population of north India. 61
18579988 2008
20
Proteomic analysis of climatic keratopathy droplets. 61
18378572 2008
21
Epidemiological characteristics of corneal ulcers in South sharqiya region. 61
22567208 2008
22
Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy. 61
17667612 2007
23
Superficial keratectomy using microkeratome for treatment of irregular climatic droplet keratopathy (free flap). 61
16705450 2007
24
Advanced glycation end product deposits in climatic droplet keratopathy. 61
16973666 2007
25
Excimer laser phototherapeutic keratectomy. 61
17146575 2006
26
Climatic droplet keratopathy in the Argentine Patagonia. 61
16564815 2006
27
Indications and outcome of optical partial thickness lamellar keratoplasty. 61
12605042 2003
28
Photokeratitis and other phototoxic effects on the cornea and conjunctiva. 61
12537642 2002
29
Exfoliation syndrome: frequency, gender distribution and association with climatically induced alterations of the cornea and conjunctiva. 61
12390157 2002
30
Infectious keratitis in climatic droplet keratopathy. 61
10928756 2000
31
Human papilloma virus in neoplastic and non-neoplastic conditions of the external eye. 61
9290377 1997
32
Ultraviolet radiation revisited. 61
9240832 1997
33
Recurrence of climatic droplet keratopathy. Two case reports. 61
9017061 1996
34
Climatic droplet keratopathy in leprosy. 61
8627116 1996
35
Bacterial keratitis following phototherapeutic keratectomy. 61
8963801 1996
36
Phototherapeutic keratectomy for climatic droplet keratopathy, KKESH Excimer Laser Study Group. King Khaled Eye Specialist Hospital. 61
8963799 1996
37
Changes of the eye caused by the climate in Rwanda, Africa. 61
7585235 1995
38
Solar ultraviolet radiation and ocular disease: a review of the epidemiological and experimental evidence. 61
8790622 1994
39
Climatic droplet keratopathy. 61
7936560 1994
40
Climatic droplet keratopathy. 61
7936561 1994
41
The relationship between cataract and climatic droplet keratopathy in Mongolia. 61
7825419 1994
42
Light damage to the eye. 61
8046363 1994
43
Prevalence and causes of blindness and visual impairment in Mongolia: a survey of populations aged 40 years and older. 61
7955027 1994
44
The long-term effects of visible light on the eye. 61
1731731 1992
45
Climatic droplet keratopathy. 61
1549808 1992
46
Climatic droplet keratopathy, exfoliation syndrome, and cataract. 61
1768663 1991
47
Ocular and facial skin exposure to ultraviolet radiation in sunlight: a personal exposure model with application to a worker population. 61
2061052 1991
48
Climatic droplet keratopathy with corneal amyloidosis. 61
2008277 1991
49
Visual outcome and complications after cataract extraction in Saudi Arabia. 61
2322510 1990
50
Albedo concentration in the anterior eye: a phenomenon that locates some solar diseases. 61
2325997 1990

Variations for Climatic Droplet Keratopathy

Expression for Climatic Droplet Keratopathy

Search GEO for disease gene expression data for Climatic Droplet Keratopathy.

Pathways for Climatic Droplet Keratopathy

GO Terms for Climatic Droplet Keratopathy

Cellular components related to Climatic Droplet Keratopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 8.96 LACRT JCHAIN
2 extracellular space GO:0005615 8.62 LACRT JCHAIN

Sources for Climatic Droplet Keratopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....