MCID: CLV002
MIFTS: 42

Clivus Chordoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Clivus Chordoma

MalaCards integrated aliases for Clivus Chordoma:

Name: Clivus Chordoma 12 15
Chordoma of Clivus 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:6312
NCIt 50 C5412
UMLS 73 C1333071

Summaries for Clivus Chordoma

Disease Ontology : 12 A chordoma of skull base that is located in the clivus.

MalaCards based summary : Clivus Chordoma, also known as chordoma of clivus, is related to chordoma and tuberous sclerosis, and has symptoms including headache An important gene associated with Clivus Chordoma is HOXA10 (Homeobox A10), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. Affiliated tissues include bone, brain and lung, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Clivus Chordoma

Diseases related to Clivus Chordoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 chordoma 10.8
2 tuberous sclerosis 10.2
3 spastic paraplegia 25, autosomal recessive 10.1 FGF13 FGF2
4 adhesive otitis media 10.1 ATM FGF2
5 mucinous lung adenocarcinoma 10.1 ERBB3 FGFR1 IGF1R
6 diffuse glomerulonephritis 10.1 FGF13 FGF2
7 tuberous sclerosis 1 10.1
8 quadriplegia 10.1
9 herpes simplex 10.1
10 meningitis 10.1
11 arachnoid cysts 10.1
12 gastric signet ring cell adenocarcinoma 10.1 FGF13 FGF2
13 crouzon syndrome 10.1 FGF13 FGF2 FGFR1
14 muenke syndrome 10.1 FGF13 FGF2 FGFR1
15 cornea cancer 10.0 CDK4 FGF2
16 synovial chondromatosis 10.0 FGF2 FGFR1
17 dedifferentiated liposarcoma 10.0 CDK4 IGF1R
18 brachydactyly, type b2 10.0 FGF13 FGF2
19 synchronous bilateral breast carcinoma 10.0 ATM PTEN
20 sporadic breast cancer 10.0 ATM CHEK2 PTEN
21 hereditary breast ovarian cancer syndrome 10.0 ATM CHEK2 PTEN
22 li-fraumeni syndrome 9.9 ATM CHEK2 PTEN
23 endometrial adenocarcinoma 9.9 FGF2 HOXA10 PTEN
24 gliosarcoma 9.9 CDK4 FGFR1 PTEN
25 mantle cell lymphoma 9.9 ATM CDK4 PARP1
26 hematologic cancer 9.9 ATM CXCL12 FGFR1 HOXA9
27 infiltrating lipoma 9.9 CDK4 FGF2
28 aging 9.9 CHEK2 PARP1 PTEN
29 adenocarcinoma 9.8 CDK4 ERBB3 FGFR1 PTEN
30 lung cancer susceptibility 3 9.8 CDK4 ERBB3 IGF1R PARP1
31 myeloma, multiple 9.8 CDK4 CXCL12 FGF2 PARP1
32 squamous cell carcinoma, head and neck 9.8 CDK4 ERBB3 FGF2 PTEN
33 glioma 9.7 CDK4 FGF2 FGFR1 PTEN
34 glioblastoma 9.7 CDK4 ERBB3 FGFR1 IGF1R PTEN
35 adamantinoma of long bones 9.7 CDK4 FGF2 PARP1 PTEN
36 ewing sarcoma 9.7 CDK4 FGF2 FGFR1 IGF1R PARP1
37 esophageal cancer 9.6 CDK4 CHEK2 FGF2 IGF1R PTEN
38 leukemia, acute myeloid 9.5 CXCL12 HOXA10 HOXA7 HOXA9 PARP1
39 medulloblastoma 9.5 CDK4 ERBB3 FGFR1 IGF1R PARP1 PTEN
40 ovarian cancer 9.5 ATM CDK4 CHEK2 ERBB3 PARP1 PTEN
41 large intestine cancer 9.4 CDK4 CHEK2 CXCL12 ERBB3 IGF1R PARP1
42 hepatocellular carcinoma 9.4 CDK4 FGF2 FGFR1 IGF1R PARP1 PTEN
43 lung cancer 9.3 ATM CDK4 CHEK2 ERBB3 FGFR1 IGF1R
44 prostate cancer 9.2 CDK4 CHEK2 ERBB3 FGF2 FGFR1 IGF1R
45 breast cancer 9.0 ATM CDK4 CHEK2 CXCL12 ERBB3 FGF2

Graphical network of the top 20 diseases related to Clivus Chordoma:



Diseases related to Clivus Chordoma

Symptoms & Phenotypes for Clivus Chordoma

UMLS symptoms related to Clivus Chordoma:


headache

GenomeRNAi Phenotypes related to Clivus Chordoma according to GeneCards Suite gene sharing:

26 (show all 47)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00106-A-0 10.11 ERBB3
2 Decreased viability GR00221-A-1 10.11 IGF1R
3 Decreased viability GR00221-A-2 10.11 CHEK2 ERBB3 IGF1R
4 Decreased viability GR00221-A-3 10.11 CHEK2 IGF1R
5 Decreased viability GR00221-A-4 10.11 CHEK2 ERBB3
6 Decreased viability GR00301-A 10.11 ERBB3 IGF1R
7 Decreased viability GR00342-S-2 10.11 CHEK2 ERBB3 IGF1R
8 Decreased viability GR00342-S-3 10.11 ERBB3
9 Decreased viability GR00402-S-2 10.11 CHEK2 ERBB3 IGF1R
10 Decreased substrate adherent cell growth GR00193-A-1 10.1 ERBB3 IGF1R
11 Decreased substrate adherent cell growth GR00193-A-2 10.1 ATM CDK4 ERBB3
12 Decreased substrate adherent cell growth GR00193-A-3 10.1 CDK4 CHEK2
13 Decreased substrate adherent cell growth GR00193-A-4 10.1 CDK4 CHEK2 FGFR1 IGF1R
14 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.9 ATM
15 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.9 ATM
16 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.9 ATM CHEK2 IGF1R
17 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.9 CDK4
18 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.9 ERBB3
19 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.9 CHEK2
20 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.9 ATM
21 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.9 CHEK2
22 Increased shRNA abundance (Z-score > 2) GR00366-A-127 9.9 IGF1R
23 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.9 ATM
24 Increased shRNA abundance (Z-score > 2) GR00366-A-151 9.9 ATM
25 Increased shRNA abundance (Z-score > 2) GR00366-A-159 9.9 ATM
26 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.9 ATM ERBB3
27 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.9 IGF1R
28 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.9 IGF1R
29 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.9 ERBB3
30 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.9 IGF1R
31 Increased shRNA abundance (Z-score > 2) GR00366-A-207 9.9 CHEK2
32 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.9 CDK4
33 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.9 ATM IGF1R
34 Increased shRNA abundance (Z-score > 2) GR00366-A-215 9.9 ATM
35 Increased shRNA abundance (Z-score > 2) GR00366-A-41 9.9 ATM
36 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.9 CDK4
37 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.9 IGF1R
38 Increased shRNA abundance (Z-score > 2) GR00366-A-46 9.9 CDK4
39 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.9 IGF1R
40 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.9 IGF1R
41 Increased shRNA abundance (Z-score > 2) GR00366-A-8 9.9 ATM
42 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.9 ATM
43 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.9 ATM CDK4 CHEK2 ERBB3 IGF1R
44 Decreased human cytomegalovirus (HCMV) strain AD169 replication GR00248-A 9.72 ATM CHEK2 ERBB3 FGFR1 IGF1R
45 Condensed cis-Golgi GR00365-A 9.67 ERBB3 FGFR1 IGF1R PTEN
46 Apoptosis resistance GR00093-A-0 9.58 ATM CHEK2 PTEN
47 Increased cell viability after pRB stimulation GR00230-A-1 9.26 CDK4 CHEK2 ERBB3 IGF1R

MGI Mouse Phenotypes related to Clivus Chordoma:

46 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.28 ATM CDK4 CHEK2 CXCL12 ERBB3 FGF13
2 behavior/neurological MP:0005386 10.21 ATM CDK4 ERBB3 FGF13 FGF2 FGFR1
3 hematopoietic system MP:0005397 10.2 ATM CDK4 CHEK2 CXCL12 FGF2 FGFR1
4 endocrine/exocrine gland MP:0005379 10.19 ATM CDK4 CHEK2 ERBB3 FGFR1 HOXA10
5 immune system MP:0005387 10.17 ATM CDK4 CHEK2 CXCL12 ERBB3 FGFR1
6 cardiovascular system MP:0005385 10.15 ATM CDK4 CXCL12 ERBB3 FGF2 FGFR1
7 growth/size/body region MP:0005378 10.13 ATM CDK4 ERBB3 FGFR1 HOXA10 HOXA9
8 mortality/aging MP:0010768 10.11 ATM CDK4 CHEK2 CXCL12 ERBB3 FGF13
9 embryo MP:0005380 10.05 ATM CDK4 ERBB3 FGFR1 IGF1R PARP1
10 integument MP:0010771 10.01 ATM CDK4 ERBB3 FGFR1 HOXA9 IGF1R
11 digestive/alimentary MP:0005381 10 CDK4 ERBB3 FGFR1 HOXA10 IGF1R PTEN
12 nervous system MP:0003631 9.93 ATM CDK4 CHEK2 CXCL12 ERBB3 FGF13
13 muscle MP:0005369 9.87 CDK4 CXCL12 ERBB3 FGF2 FGFR1 IGF1R
14 neoplasm MP:0002006 9.8 ATM CDK4 CHEK2 ERBB3 FGF2 IGF1R
15 reproductive system MP:0005389 9.65 ATM CDK4 CXCL12 FGF2 FGFR1 HOXA10
16 skeleton MP:0005390 9.17 FGF2 FGFR1 HOXA10 HOXA7 HOXA9 IGF1R

Drugs & Therapeutics for Clivus Chordoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors Completed NCT00931931 Phase 1

Search NIH Clinical Center for Clivus Chordoma

Genetic Tests for Clivus Chordoma

Anatomical Context for Clivus Chordoma

MalaCards organs/tissues related to Clivus Chordoma:

41
Bone, Brain, Lung, Breast, Prostate, T Cells, Myeloid

Publications for Clivus Chordoma

Articles related to Clivus Chordoma:

(show all 29)
# Title Authors Year
1
Cardiac Metastasis from Clivus Chordoma. ( 29454123 )
2018
2
An unusual case of acquired pedophilic behavior following compression of orbitofrontal cortex and hypothalamus by a Clivus Chordoma. ( 27159984 )
2016
3
Sustained response of a clivus chordoma to erlotinib after imatinib failure. ( 25762924 )
2015
4
Experimental Study on Differences in Clivus Chordoma Bone Invasion: An iTRAQ-Based Quantitative Proteomic Analysis. ( 25793716 )
2015
5
On "clivus chordoma: is it enough to image the primary site?" (skull base 2010;20:111-113). ( 22470272 )
2011
6
Clivus chordoma: is it enough to image the primary site? ( 20808536 )
2010
7
The transnasal transclival approach for clivus chordoma. ( 21302187 )
2010
8
Clivus chordoma in continuity with a large pontine cyst. ( 19721775 )
2009
9
[Limitation of medical treatment and ethics in chronic recurrent Clivus chordoma]. ( 19165442 )
2008
10
Infantile clivus chordoma without clivus involvement: case report and review of the literature. ( 16565853 )
2006
11
Recurrent and metastatic clivus chordoma: systemic palliative therapy retards disease progression. ( 16222158 )
2005
12
Clivus chordoma associated with a pontine arachnoid cyst. ( 15992705 )
2005
13
Candida albicans granuloma imitate clivus chordoma. ( 12111509 )
2002
14
Does the tuberous sclerosis complex include clivus chordoma? A case report. ( 11271387 )
2001
15
Clivus chordoma. ( 9322379 )
1997
16
Herpes simplex meningitis after surgical removal of a clivus chordoma. ( 9177973 )
1997
17
Congenital clivus chordoma. ( 8517337 )
1993
18
Proton radiation therapy for clivus chordoma--case report. ( 7683125 )
1993
19
Transoral transpalatal removal of a giant premesencephalic clivus chordoma. ( 1776517 )
1991
20
Clivus chordoma: a report of 12 recent cases and review of the literature. ( 17170837 )
1991
21
Surgical access for clivus chordoma. The University of California, San Francisco, experience. ( 2917064 )
1989
22
Clivus chordoma in childhood. ( 3589943 )
1987
23
Clivus chordoma in a child with tuberous sclerosis: CT and MR demonstration. ( 3805419 )
1987
24
Clivus chordoma in a 9-year-old child: case report and review of the literature. ( 3152925 )
1987
25
Bilateral abducens nerve palsies from clivus chordoma. ( 7258964 )
1981
26
Clivus chordoma with distinct vascularity demonstrated by angiography. ( 896037 )
1977
27
Clivus chordoma with unusual bone sclerosis and brainstem invasion. A case report with review of the radiology of cranial chordomas. ( 1212128 )
1975
28
Transcervical removal of a clivus chordoma in a 2-year-old child. Reversal of quadriplegia and bulbar paralysis. ( 5531855 )
1970
29
A transcervical transclival approach to the ventral surface of the brain stem for removal of a clivus chordoma. ( 5295919 )
1966

Variations for Clivus Chordoma

Expression for Clivus Chordoma

Search GEO for disease gene expression data for Clivus Chordoma.

Pathways for Clivus Chordoma

Pathways related to Clivus Chordoma according to GeneCards Suite gene sharing:

(show all 49)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.71 ATM CHEK2 CXCL12 ERBB3 FGF13 FGF2
2
Show member pathways
13.66 ATM CDK4 CHEK2 CXCL12 ERBB3 FGF13
3
Show member pathways
13.32 CXCL12 ERBB3 FGF13 FGF2 FGFR1 IGF1R
4
Show member pathways
13.21 CXCL12 FGF13 FGF2 FGFR1 IGF1R PTEN
5
Show member pathways
13.21 CXCL12 ERBB3 FGF13 FGF2 FGFR1 IGF1R
6
Show member pathways
13.19 CXCL12 ERBB3 FGF13 FGF2 FGFR1 IGF1R
7
Show member pathways
12.98 CXCL12 FGF13 FGF2 FGFR1 IGF1R PTEN
8
Show member pathways
12.97 ATM CDK4 CXCL12 FGF2 PTEN
9
Show member pathways
12.96 CXCL12 FGF13 FGF2 FGFR1 IGF1R
10
Show member pathways
12.71 ATM CDK4 ERBB3 FGF2 FGFR1 IGF1R
11
Show member pathways
12.69 CDK4 FGF2 FGFR1 IGF1R PTEN
12 12.67 ERBB3 FGF2 FGFR1 IGF1R
13
Show member pathways
12.64 ERBB3 FGF2 FGFR1 PTEN
14 12.63 CDK4 CXCL12 FGF2 FGFR1 IGF1R PTEN
15
Show member pathways
12.61 ATM CDK4 CHEK2 PARP1
16
Show member pathways
12.61 CXCL12 FGF13 FGF2 FGFR1
17 12.54 CXCL12 FGF13 FGF2 FGFR1
18
Show member pathways
12.42 ERBB3 FGFR1 IGF1R PTEN
19
Show member pathways
12.34 FGF13 FGF2 FGFR1 PARP1
20
Show member pathways
12.32 ATM CDK4 CHEK2 PTEN
21
Show member pathways
12.28 ATM CHEK2 ERBB3 FGFR1 IGF1R
22 12.24 ERBB3 FGF2 FGFR1 IGF1R
23 12.19 ATM HOXA10 HOXA9 IGF1R
24
Show member pathways
12.18 CXCL12 ERBB3 FGF13 FGF2 FGFR1 IGF1R
25
Show member pathways
12.17 ATM CDK4 CHEK2 PTEN
26 12.1 ATM CDK4 CHEK2 PTEN
27 12.06 ATM CDK4 CHEK2 PTEN
28
Show member pathways
12.06 CDK4 ERBB3 FGFR1 IGF1R PTEN
29 12.03 ERBB3 FGF2 FGFR1 IGF1R
30 12.01 FGF2 FGFR1 IGF1R
31
Show member pathways
12 ATM IGF1R PTEN
32
Show member pathways
12 CXCL12 FGF13 FGF2 FGFR1
33
Show member pathways
11.94 ATM CXCL12 FGF13 FGF2 FGFR1 IGF1R
34 11.92 CDK4 ERBB3 FGFR1 IGF1R PTEN
35 11.89 CDK4 IGF1R PTEN
36
Show member pathways
11.84 ATM CDK4 ERBB3 FGF2 FGFR1 IGF1R
37 11.82 ATM CXCL12 PARP1
38 11.64 ATM CHEK2 PTEN
39 11.63 FGF2 FGFR1 IGF1R
40 11.45 ERBB3 FGFR1 IGF1R
41 11.42 ATM CDK4 CHEK2
42 11.22 CXCL12 FGF2 FGFR1
43 11.12 FGF2 FGFR1
44 11.12 ATM CDK4 CHEK2 PTEN
45 11.12 CXCL12 ERBB3 FGF13 FGF2 FGFR1 IGF1R
46 11.06 ATM CHEK2 PARP1
47 11.04 ATM PTEN
48 11.01 FGF13 FGF2 FGFR1 PARP1
49 10.89 CXCL12 ERBB3 FGF13 FGF2 FGFR1 IGF1R

GO Terms for Clivus Chordoma

Cellular components related to Clivus Chordoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.9 ATM CDK4 CHEK2 CXCL12 ERBB3 FGF13
2 nucleus GO:0005634 9.7 ATM CDK4 CHEK2 FGF13 FGF2 FGFR1
3 transcription factor complex GO:0005667 8.92 CDK4 HOXA10 HOXA9 PARP1

Biological processes related to Clivus Chordoma according to GeneCards Suite gene sharing:

(show all 29)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein kinase B signaling GO:0051897 9.82 ERBB3 FGF2 FGFR1
2 angiogenesis GO:0001525 9.81 FGF2 FGFR1 HOXA7 PTEN
3 regulation of cell cycle GO:0051726 9.8 ATM CDK4 PTEN
4 negative regulation of signal transduction GO:0009968 9.79 ERBB3 FGFR1 IGF1R
5 phosphatidylinositol phosphorylation GO:0046854 9.78 ERBB3 FGF2 FGFR1
6 MAPK cascade GO:0000165 9.78 ERBB3 FGF13 FGF2 FGFR1
7 neuron migration GO:0001764 9.77 CXCL12 FGF13 FGFR1
8 anterior/posterior pattern specification GO:0009952 9.77 HOXA10 HOXA7 HOXA9
9 regulation of gene expression GO:0010468 9.76 CDK4 FGFR1 HOXA10 HOXA9
10 cellular response to insulin stimulus GO:0032869 9.73 CDK4 PARP1 PTEN
11 phosphorylation GO:0016310 9.73 ATM CDK4 CHEK2 ERBB3 FGFR1 IGF1R
12 positive regulation of neuron differentiation GO:0045666 9.71 CXCL12 FGFR1 PTEN
13 peptidyl-tyrosine phosphorylation GO:0018108 9.67 ERBB3 FGF2 FGFR1 IGF1R
14 proximal/distal pattern formation GO:0009954 9.64 HOXA10 HOXA9
15 negative regulation of cell cycle arrest GO:0071157 9.63 CDK4 CHEK2
16 positive regulation of vascular endothelial cell proliferation GO:1905564 9.63 FGF2 FGFR1
17 protein phosphorylation GO:0006468 9.63 ATM CDK4 CHEK2 ERBB3 FGFR1 IGF1R
18 uterus development GO:0060065 9.62 HOXA10 HOXA9
19 protein autophosphorylation GO:0046777 9.62 ATM CHEK2 FGFR1 IGF1R
20 phosphatidylinositol-3-phosphate biosynthetic process GO:0036092 9.61 ATM FGF2 FGFR1
21 positive regulation of phospholipase C activity GO:0010863 9.58 FGF2 FGFR1
22 replicative senescence GO:0090399 9.58 ATM CHEK2
23 DNA damage induced protein phosphorylation GO:0006975 9.52 ATM CHEK2
24 obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle GO:0031658 9.49 CDK4 PTEN
25 positive regulation of cell proliferation GO:0008284 9.43 CDK4 CXCL12 FGF2 FGFR1 IGF1R PTEN
26 positive regulation of endothelial cell chemotaxis to fibroblast growth factor GO:2000546 9.4 FGF2 FGFR1
27 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.02 ERBB3 FGF2 FGFR1 IGF1R PTEN
28 signal transduction GO:0007165 10.11 ATM CDK4 CXCL12 ERBB3 FGF13 FGF2
29 positive regulation of transcription by RNA polymerase II GO:0045944 10.02 ATM FGF2 HOXA10 HOXA7 HOXA9 PARP1

Molecular functions related to Clivus Chordoma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.93 CHEK2 ERBB3 FGFR1 IGF1R PARP1 PTEN
2 protein kinase activity GO:0004672 9.83 CDK4 CHEK2 ERBB3 FGFR1 IGF1R
3 growth factor activity GO:0008083 9.71 CXCL12 FGF13 FGF2
4 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.69 ERBB3 FGF2 FGFR1
5 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.58 ERBB3 FGF2 FGFR1
6 nucleotide binding GO:0000166 9.55 ATM CDK4 CHEK2 ERBB3 FGFR1
7 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.54 ERBB3 FGFR1 IGF1R
8 1-phosphatidylinositol-3-kinase activity GO:0016303 9.43 ATM FGF2 FGFR1
9 receptor-receptor interaction GO:0090722 9.32 FGF2 FGFR1
10 protein tyrosine kinase activity GO:0004713 9.26 ERBB3 FGF2 FGFR1 IGF1R
11 kinase activity GO:0016301 9.1 ATM CDK4 CHEK2 ERBB3 FGFR1 IGF1R
12 protein binding GO:0005515 10.31 ATM CDK4 CHEK2 CXCL12 ERBB3 FGF13
13 transferase activity GO:0016740 10.02 ATM CDK4 CHEK2 ERBB3 FGFR1 IGF1R
14 ATP binding GO:0005524 10 ATM CDK4 CHEK2 ERBB3 FGFR1 IGF1R

Sources for Clivus Chordoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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