MCID: CLC003
MIFTS: 23

Cloacogenic Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Cloacogenic Carcinoma

MalaCards integrated aliases for Cloacogenic Carcinoma:

Name: Cloacogenic Carcinoma 12 15 70
Cloacogenic Anal Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7173
NCIt 50 C8255
SNOMED-CT 67 84570003
UMLS 70 C0334273

Summaries for Cloacogenic Carcinoma

MalaCards based summary : Cloacogenic Carcinoma, also known as cloacogenic anal carcinoma, is related to basaloid squamous cell carcinoma and neuroendocrine carcinoma. An important gene associated with Cloacogenic Carcinoma is KERA (Keratocan). Affiliated tissues include pineal, lung and colon.

Related Diseases for Cloacogenic Carcinoma

Diseases related to Cloacogenic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 180)
# Related Disease Score Top Affiliating Genes
1 basaloid squamous cell carcinoma 30.4 SYP ENO2
2 neuroendocrine carcinoma 29.9 SYP ENO2
3 rectal cloacogenic carcinoma 11.3
4 rare tumor 10.3
5 spindle cell thymoma 10.2 KRT5 ENO2
6 vulvar apocrine adenocarcinoma 10.2 KRT5 ENO2
7 liver leiomyosarcoma 10.2 KRT5 ENO2
8 uterus leiomyosarcoma 10.2 KRT5 ENO2
9 rectum cancer 10.1
10 squamous cell papilloma 10.1
11 papilloma 10.1
12 bartholin's gland adenocarcinoma 10.1 SLC45A3 KRT5
13 sweat gland benign neoplasm 10.1 ZNF444 KRT5
14 sweat gland disease 10.1 ZNF444 KRT5
15 reticulate acropigmentation of kitamura 10.0 KRT5 KRT4
16 dyschromatosis universalis hereditaria 10.0 KRT5 KRT4
17 skin benign neoplasm 10.0 KRT5 ENO2
18 epidermolysis bullosa simplex with mottled pigmentation 10.0 KRT5 KRT4
19 olfactory neuroblastoma 10.0 SYP ENO2
20 malignant melanocytic neoplasm of the peripheral nerve sheath 10.0 SYP ENO2
21 anal neuroendocrine tumor 10.0 SYP ENO2
22 optic nerve astrocytoma 10.0 SYP ENO2
23 cerebral neuroblastoma 10.0 SYP ENO2
24 neuronal intestinal dysplasia, type b 10.0 SYP ENO2
25 lung meningioma 10.0 SYP ENO2
26 sinonasal undifferentiated carcinoma 10.0 SYP ENO2
27 papillary tumor of the pineal region 10.0 SYP ENO2
28 auditory system cancer 10.0 SYP ENO2
29 pineal region teratoma 10.0 SYP ENO2
30 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.0 SYP ENO2
31 cauda equina neoplasm 10.0 SYP ENO2
32 intracranial primitive neuroectodermal tumor 10.0 SYP ENO2
33 bile duct mucinous adenocarcinoma 10.0 SYP ENO2
34 nodular prostate 10.0 SYP ENO2
35 ampulla of vater benign neoplasm 10.0 SYP ENO2
36 appendix carcinoid tumor 10.0 SYP ENO2
37 carotid body cancer 10.0 SYP ENO2
38 small cell carcinoma 10.0 SYP ENO2
39 gallbladder small cell carcinoma 10.0 SYP ENO2
40 ureter small cell carcinoma 10.0 SYP ENO2
41 cerebellar liponeurocytoma 10.0 SYP ENO2
42 middle ear adenoma 10.0 SYP ENO2
43 cerebellopontine angle primitive neuroectodermal tumor 10.0 SYP ENO2
44 urinary bladder small cell neuroendocrine carcinoma 10.0 SYP ENO2
45 gastric small cell carcinoma 10.0 SYP ENO2
46 extracranial neuroblastoma 10.0 SYP ENO2
47 jejunal neoplasm 10.0 SYP ENO2
48 epidermolysis bullosa simplex, dowling-meara type 10.0 KRT5 KRT4
49 frontal lobe neoplasm 10.0 SYP ENO2
50 cervical neuroblastoma 10.0 SYP ENO2

Graphical network of the top 20 diseases related to Cloacogenic Carcinoma:



Diseases related to Cloacogenic Carcinoma

Symptoms & Phenotypes for Cloacogenic Carcinoma

Drugs & Therapeutics for Cloacogenic Carcinoma

Search Clinical Trials , NIH Clinical Center for Cloacogenic Carcinoma

Genetic Tests for Cloacogenic Carcinoma

Anatomical Context for Cloacogenic Carcinoma

MalaCards organs/tissues related to Cloacogenic Carcinoma:

40
Pineal, Lung, Colon, Thymus, Kidney, Breast, Prostate

Publications for Cloacogenic Carcinoma

Articles related to Cloacogenic Carcinoma:

(show top 50) (show all 115)
# Title Authors PMID Year
1
HPV related cloacogenic carcinoma of the anal canal with divergent histomorphology. 61
31361242 2019
2
Survival rate variation with different histological subtypes of poor prognostic male anal squamous cell carcinoma: a population-based study. 61
29137429 2017
3
Basaloid Squamous Cell Carcinoma of the Anus Revisited. 61
26866355 2016
4
The rising incidence of anal cancer in England 1990-2010: a population-based study. 61
24410872 2014
5
Molecular and immunohistochemical profile of a basaloid (cloacogenic) carcinoma of the sigmoid colon: possible predictive value for clinical outcomes. 61
24584270 2014
6
[Hepatic cyst in a patient with anorectal cloacogenic carcinoma: metastasis or benign liver disease?]. 61
22177268 2012
7
What is the clinicopathological characteristic of cloacogenic carcinoma outside the anorectal zone? 61
21510286 2011
8
FDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma. 61
20137093 2010
9
Aggressive treatment approach for cloacogenic carcinoma of the anorectum: report from a single cancer center. 61
20689291 2010
10
Basaloid (Cloacogenic) Carcinoma Mimicking Intraabdominal Abscess: Report of a Case and Review of the Literature. 61
21103283 2009
11
PNET/Ewing's sarcoma of the rectum: a case report and review of the literature. 61
21691396 2009
12
[Protruding isolated rectal and anal neoplastic polyps removed by local transanal excision: our experience with 16 cases]. 61
18689170 2008
13
Anal canal carcinoma: experience from a single Korean institution. 61
17963341 2007
14
Case report of long term survivor of metastatic cloacogenic carcinoma of the anal canal with chemotherapy. 61
20084726 2007
15
The demographics, histopathology and patterns of treatment of anal cancer in Connecticut: 1980-2000. 61
16114640 2005
16
Chemotherapy and radiation of anal canal cancer: the first approach. 61
15137959 2004
17
HIV-positive patients with anal carcinoma have poorer treatment tolerance and outcome than HIV-negative patients. 61
11598480 2001
18
Anal carcinoma: a 15-year retrospective analysis. 61
11145292 2000
19
Extrauterine malignancies. Role of Pap smears in diagnosis and management. 61
10518134 1999
20
Cloacogenic adenocarcinoma of the vulva. 61
10419750 1999
21
An unusual location of cloacogenic carcinoma. 61
10096758 1998
22
Diagnosis and differential diagnosis of small-cell lesions of the liver. 61
9664180 1998
23
[Cancer of the anal canal]. 61
9480525 1997
24
Inflammatory cutaneous metastases from cloacogenic carcinoma of the anus. 61
7633821 1995
25
Skin cancers associated with acquired immunodeficiency syndrome. 61
7630215 1995
26
Transanal excision of rectal carcinoma. 61
7618812 1995
27
[A cloacogenic anal carcinoma in an adolescent]. 61
7612375 1995
28
Cloacogenic anal carcinoma presenting with humoral hypercalcemia: report of a case. 61
8640024 1995
29
[Cloacogenic carcinoma with reference to malignant tumors of the anal canal]. 61
7837635 1994
30
[The prognostic factors following the simultaneous radiochemotherapy of anal canal carcinoma in a multicenter series of 139 patients]. 61
8052938 1994
31
[Surgical treatment of anorectal disorders in 32 HIV-seropositive patients]. 61
8015620 1994
32
[Perianal basal cell carcinoma. Apropos of 2 cases]. 61
7702280 1994
33
[Heterotopic cloacogenic carcinoma of the lower lip]. 61
7979028 1994
34
[Cloacogenic carcinoma with reference to malignant tumors of the anal canal]. 61
7736207 1994
35
[Adenocarcinoma of anal canal. Report of a case and review of the literature]. 61
7701908 1994
36
Irradiation in the management of anal cancer with literature review. 61
8320504 1993
37
External radiation therapy without chemotherapy in the management of anal cancer. 61
8448738 1993
38
Perianal basal cell carcinoma. 61
1458647 1992
39
Surgical treatment of female urethral carcinoma. 61
1574827 1992
40
Mixed cloacogenic carcinoma of male urethra. 61
1737633 1992
41
Cloacogenic carcinoma of the anal canal and associated viral lesions. An in situ hybridization study for human papilloma virus. 61
1657356 1991
42
Newer variants and simulants of basal cell carcinoma. 61
1885825 1991
43
[Spontaneous regression of liver metastases in neuroendocrine tumors of the abdomen]. 61
2057755 1991
44
Cytokeratin polypeptide expression in a cloacogenic carcinoma and in the normal anal canal epithelium. 61
1709765 1991
45
Transitional cloacogenic carcinoma of the female urethra treated with external irradiation and afterloading with cobalt-60. 61
2024362 1991
46
Multicentric cloacogenic carcinoma: report of a case with anogenital pruritus at presentation. 61
2229531 1990
47
Neurologic complications of cloacogenic carcinoma. 61
2389732 1990
48
[A case of cloacogenic carcinoma with extra-visceral localization]. 61
2392255 1990
49
Combined chemotherapy and radiotherapy for carcinomas of the anus. 61
2334018 1990
50
Anal cloacogenic and squamous carcinomas. Comparative histologic analysis using in situ hybridization for human papillomavirus DNA. 61
2154141 1990

Variations for Cloacogenic Carcinoma

Expression for Cloacogenic Carcinoma

Search GEO for disease gene expression data for Cloacogenic Carcinoma.

Pathways for Cloacogenic Carcinoma

GO Terms for Cloacogenic Carcinoma

Sources for Cloacogenic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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