MCID: CCN009
MIFTS: 21

Cocaine Intoxication

Categories: Rare diseases

Aliases & Classifications for Cocaine Intoxication

MalaCards integrated aliases for Cocaine Intoxication:

Name: Cocaine Intoxication 59 55 73

Characteristics:

Orphanet epidemiological data:

59
cocaine intoxication
Age of onset: All ages; Age of death: any age;

Classifications:



External Ids:

Orphanet 59 ORPHA90068
ICD10 via Orphanet 34 T40.5
UMLS 73 C0009176

Summaries for Cocaine Intoxication

MalaCards based summary : Cocaine Intoxication is related to diabetes mellitus, ketosis-prone and ventricular fibrillation, paroxysmal familial, 1. An important gene associated with Cocaine Intoxication is BCHE (Butyrylcholinesterase). The drugs Dopamine and Cocaine have been mentioned in the context of this disorder. Affiliated tissues include thyroid and liver.

Wikipedia : 76 Cocaine intoxication refers to the immediate and deleterious effects of cocaine on the body. Although... more...

Related Diseases for Cocaine Intoxication

Diseases related to Cocaine Intoxication via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 diabetes mellitus, ketosis-prone 9.9
2 ventricular fibrillation, paroxysmal familial, 1 9.8
3 hepatitis c virus 9.8
4 acute liver failure 9.8
5 alcoholic hepatitis 9.8
6 hepatitis 9.8
7 cardiac arrest 9.8
8 thrombosis 9.8
9 eclampsia 9.8
10 hepatitis c 9.8
11 perinephritis 9.8
12 lactic acidosis 9.8
13 thyroiditis 9.8

Graphical network of the top 20 diseases related to Cocaine Intoxication:



Diseases related to Cocaine Intoxication

Symptoms & Phenotypes for Cocaine Intoxication

Drugs & Therapeutics for Cocaine Intoxication

Drugs for Cocaine Intoxication (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 2 51-61-6, 62-31-7 681
2
Cocaine Approved, Illicit Phase 2 50-36-2 5760 446220
3 Central Nervous System Depressants Phase 2
4 Neurotransmitter Agents Phase 2
5 Neurotransmitter Uptake Inhibitors Phase 2
6 Anesthetics Phase 2
7 Anesthetics, Local Phase 2
8 Vaccines Phase 2
9 Dopamine Agents Phase 2
10 Vasoconstrictor Agents Phase 2
11 Dopamine Uptake Inhibitors Phase 2
12 Peripheral Nervous System Agents Phase 2
13 Antibodies Phase 2
14 Immunoglobulins Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Therapeutic Cocaine Vaccine: Human Laboratory Study Completed NCT00965263 Phase 2

Search NIH Clinical Center for Cocaine Intoxication

Genetic Tests for Cocaine Intoxication

Anatomical Context for Cocaine Intoxication

MalaCards organs/tissues related to Cocaine Intoxication:

41
Thyroid, Liver

Publications for Cocaine Intoxication

Articles related to Cocaine Intoxication:

(show all 27)
# Title Authors Year
1
Global cocaine intoxication research trends during 1975-2015: a bibliometric analysis of Web of Science publications. ( 28153037 )
2017
2
Euglycemic Diabetic Ketoacidosis in a Patient with Cocaine Intoxication. ( 27579186 )
2016
3
Gamma-hydroxybutyrate and cocaine intoxication in a Danish child. ( 27014439 )
2016
4
Fatal cocaine intoxication in a body packer. ( 27071289 )
2016
5
Out-of-hospital cardiac arrest after acute cocaine intoxication associated with Brugada ECG patterns: Insights into physiopathologic mechanisms and implications for therapy. ( 26048386 )
2015
6
Emotion recognition during cocaine intoxication. ( 26328908 )
2015
7
Bilateral hippocampal stroke secondary to acute cocaine intoxication. ( 26634127 )
2015
8
Significance of alanine aminotransferase levels in patients admitted for cocaine intoxication. ( 24518798 )
2015
9
Cocaine Intoxication and Thyroid Storm: Similarity in Presentation and Implications for Treatment. ( 26425625 )
2014
10
Managing combined critical hypothermia, diabetic ketoacidosis and cocaine intoxication noninvasively. ( 24342869 )
2013
11
Acute cocaine intoxication and questionnaires. ( 22882707 )
2013
12
Chronic cocaine dampens dopamine signaling during cocaine intoxication and unbalances D1 over D2 receptor signaling. ( 24089490 )
2013
13
Cocaine intoxication. ( 22998988 )
2012
14
Assessing the effect of patterns of cocaine and alcohol use on the risk of adverse acute cocaine intoxication. ( 22260083 )
2012
15
A fatally mistaken fruit juice drink: an unordinary way of cocaine intoxication. ( 21056879 )
2010
16
Lactic acidosis in restrained cocaine intoxicated patients. ( 21186707 )
2010
17
Spontaneous perinephric haemorrhage and acute renal failure in pregnancy due to cocaine intoxication. ( 28657049 )
2010
18
Cocaine intoxication and hypertension. ( 18191302 )
2008
19
Pupillary dilation, tachycardia and abnormal behaviour in a young cat. Diagnosis: cocaine intoxication. ( 17379557 )
2007
20
Effects of cocaine intoxication on the threshold for stun gun induction of ventricular fibrillation. ( 16904553 )
2006
21
Cocaine intoxication mimicking preeclampsia postpartum. ( 16246345 )
2006
22
Successful transplantation of organs from a donor who died from acute cocaine intoxication. ( 12709072 )
2003
23
Acute aortic thrombosis and renal infarction in acute cocaine intoxication: a case report and review of literature. ( 12940616 )
2003
24
Electrophysiologic and hemodynamic effects of sodium bicarbonate in a canine model of severe cocaine intoxication. ( 14677787 )
2003
25
Liver transplantation for fulminant hepatic failure due to cocaine intoxication in an alcoholic hepatitis C virus-infected patient. ( 11792999 )
2002
26
Therapeutic use of butyrylcholinesterase for cocaine intoxication. ( 9266811 )
1997
27
Cocaine intoxication presenting as preeclampsia and eclampsia. ( 8459963 )
1993

Variations for Cocaine Intoxication

Expression for Cocaine Intoxication

Search GEO for disease gene expression data for Cocaine Intoxication.

Pathways for Cocaine Intoxication

GO Terms for Cocaine Intoxication

Cellular components related to Cocaine Intoxication according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.62 BCHE GPT

Sources for Cocaine Intoxication

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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