MCID: CDN003
MIFTS: 11

Codeine Toxicity

Categories: Rare diseases

Aliases & Classifications for Codeine Toxicity

MalaCards integrated aliases for Codeine Toxicity:

Name: Codeine Toxicity 60

Classifications:



External Ids:

Orphanet 60 ORPHA240867

Summaries for Codeine Toxicity

MalaCards based summary : Codeine Toxicity is related to gastroparesis and major depressive disorder. An important gene associated with Codeine Toxicity is CYP2D6 (Cytochrome P450 Family 2 Subfamily D Member 6), and among its related pathways/superpathways are Glucose / Energy Metabolism and Statin Pathway - Generalized, Pharmacokinetics. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Codeine Toxicity

Diseases related to Codeine Toxicity via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 gastroparesis 9.6 ABCB1 CYP2D6
2 major depressive disorder 9.5 ABCB1 CYP2D6

Symptoms & Phenotypes for Codeine Toxicity

GenomeRNAi Phenotypes related to Codeine Toxicity according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.02 ABCB1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-127 9.02 ABCB1 CYP2D6
3 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.02 ABCB1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-4 9.02 CYP2D6

Drugs & Therapeutics for Codeine Toxicity

Search Clinical Trials , NIH Clinical Center for Codeine Toxicity

Genetic Tests for Codeine Toxicity

Anatomical Context for Codeine Toxicity

Publications for Codeine Toxicity

Articles related to Codeine Toxicity:

# Title Authors Year
1
Prediction of codeine toxicity in infants and their mothers using a novel combination of maternal genetic markers. ( 22398969 )
2012
2
Editors' pick: codeine toxicity prediction in young infants - genotype the mothers. ( 23186321 )
2012

Variations for Codeine Toxicity

Expression for Codeine Toxicity

Search GEO for disease gene expression data for Codeine Toxicity.

Pathways for Codeine Toxicity

Pathways related to Codeine Toxicity according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.75 ABCB1 CYP2D6
2
Show member pathways
11.21 ABCB1 CYP2D6
3
Show member pathways
11.08 ABCB1 CYP2D6
4
Show member pathways
10.43 ABCB1 CYP2D6

GO Terms for Codeine Toxicity

Sources for Codeine Toxicity

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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