MCID: CDN003
MIFTS: 11

Codeine Toxicity

Categories: Rare diseases

Aliases & Classifications for Codeine Toxicity

MalaCards integrated aliases for Codeine Toxicity:

Name: Codeine Toxicity 59

Classifications:



External Ids:

Orphanet 59 ORPHA240867

Summaries for Codeine Toxicity

MalaCards based summary : Codeine Toxicity is related to gastroparesis and major depressive disorder. An important gene associated with Codeine Toxicity is CYP2D6 (Cytochrome P450 Family 2 Subfamily D Member 6), and among its related pathways/superpathways are Glucose / Energy Metabolism and Statin Pathway - Generalized, Pharmacokinetics. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Codeine Toxicity

Diseases related to Codeine Toxicity via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 gastroparesis 9.2 ABCB1 CYP2D6
2 major depressive disorder 9.0 ABCB1 CYP2D6

Symptoms & Phenotypes for Codeine Toxicity

GenomeRNAi Phenotypes related to Codeine Toxicity according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.02 ABCB1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-127 9.02 ABCB1 CYP2D6
3 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.02 ABCB1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-4 9.02 CYP2D6

Drugs & Therapeutics for Codeine Toxicity

Search Clinical Trials , NIH Clinical Center for Codeine Toxicity

Genetic Tests for Codeine Toxicity

Anatomical Context for Codeine Toxicity

Publications for Codeine Toxicity

Articles related to Codeine Toxicity:

# Title Authors Year
1
Editors' pick: codeine toxicity prediction in young infants - genotype the mothers. ( 23186321 )
2012
2
Prediction of codeine toxicity in infants and their mothers using a novel combination of maternal genetic markers. ( 22398969 )
2012

Variations for Codeine Toxicity

Expression for Codeine Toxicity

Search GEO for disease gene expression data for Codeine Toxicity.

Pathways for Codeine Toxicity

Pathways related to Codeine Toxicity according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.86 ABCB1 CYP2D6
2
Show member pathways
11.26 ABCB1 CYP2D6
3
Show member pathways
11.15 ABCB1 CYP2D6
4
Show member pathways
10.95 ABCB1 CYP2D6
5
Show member pathways
10.7 ABCB1 CYP2D6
6
Show member pathways
10.2 ABCB1 CYP2D6

GO Terms for Codeine Toxicity

Sources for Codeine Toxicity

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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